| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neoplasm Invasiveness | D009361 | 23 associated lipids |
| Lymphedema | D008209 | 4 associated lipids |
FLAVONE
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
Cross Reference
Introduction
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with FLAVONE?
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with FLAVONE
PubChem Associated disorders and diseases
What pathways are associated with FLAVONE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with FLAVONE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with FLAVONE?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with FLAVONE?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with FLAVONE?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with FLAVONE?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with FLAVONE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| O'Leary KA et al. | Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription. | 2004 | Mutat. Res. | pmid:15225597 |
| Vaher M and Koel M | Separation of polyphenolic compounds extracted from plant matrices using capillary electrophoresis. | 2003 | J Chromatogr A | pmid:12685601 |
| Wenzel U et al. | Nitric oxide levels in human preneoplastic colonocytes determine their susceptibility toward antineoplastic agents. | 2003 | Mol. Pharmacol. | pmid:14645680 |
| Jasso-Chávez R and Moreno-Sánchez R | Cytosol-mitochondria transfer of reducing equivalents by a lactate shuttle in heterotrophic Euglena. | 2003 | Eur. J. Biochem. | pmid:14653820 |
| Morimoto M et al. | Insect antifeedant activity of flavones and chromones against Spodoptera litura. | 2003 | J. Agric. Food Chem. | pmid:12517100 |
| Fang H et al. | Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. | 2003 | Chem. Res. Toxicol. | pmid:14565775 |
| Lin HY et al. | Inhibition of lipopolysaccharide-induced nitric oxide production by flavonoids in RAW264.7 macrophages involves heme oxygenase-1. | 2003 | Biochem. Pharmacol. | pmid:14563492 |
| Zhang P et al. | A maize QTL for silk maysin levels contains duplicated Myb-homologous genes which jointly regulate flavone biosynthesis. | 2003 | Plant Mol. Biol. | pmid:12825685 |
| Xiao Z et al. | [The inhibitory effect of total flavonoids of hippophae on the activation of NF-kappa B by stretching cultured cardiac myocytes]. | 2003 | Sichuan Da Xue Xue Bao Yi Xue Ban | pmid:12947714 |
| Ahlemeyer B and Krieglstein J | Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. | 2003 | Pharmacopsychiatry | pmid:13130383 |
| Kang KW et al. | Activation of CCAAT/enhancer-binding protein beta by 2'-amino-3'-methoxyflavone (PD98059) leads to the induction of glutathione S-transferase A2. | 2003 | Carcinogenesis | pmid:12663507 |
| Gafner S et al. | Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora. | 2003 | J. Nat. Prod. | pmid:12713409 |
| Suzuki R et al. | Two flavone C-glycosides from the style of Zea mays with glycation inhibitory activity. | 2003 | J. Nat. Prod. | pmid:12713418 |
| Rudek MA et al. | Clinical pharmacology of flavopiridol following a 72-hour continuous infusion. | 2003 | Ann Pharmacother | pmid:14519054 |
| Nørbaek R et al. | Flavone C-glycoside, phenolic acid, and nitrogen contents in leaves of barley subject to organic fertilization treatments. | 2003 | J. Agric. Food Chem. | pmid:12537462 |
| Zuo L et al. | 2D-IR correlation analysis of deteriorative process of traditional Chinese medicine 'Qing Kai Ling' injection. | 2003 | J Pharm Biomed Anal | pmid:12467920 |
| Schwalm K et al. | Flavonoid-related regulation of auxin accumulation in Agrobacterium tumefaciens-induced plant tumors. | 2003 | Planta | pmid:14523649 |
| Mihara M et al. | Flavopiridol, a cyclin dependent kinase (CDK) inhibitor, induces apoptosis by regulating Bcl-x in oral cancer cells. | 2003 | Oral Oncol. | pmid:12457721 |
| Carcache-Blanco EJ et al. | Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase. | 2003 | J. Nat. Prod. | pmid:14510596 |
| Suetsugi M et al. | Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors. | 2003 | Mol. Cancer Res. | pmid:14638870 |