MeSH term | MeSH ID | Detail |
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Neoplasm Invasiveness | D009361 | 23 associated lipids |
Lymphedema | D008209 | 4 associated lipids |
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with FLAVONE
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Jameson MB et al. | Clinical aspects of a phase I trial of 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent. | 2003 | Br. J. Cancer | pmid:12799625 |
Caristi C et al. | Flavonoids detection by HPLC-DAD-MS-MS in lemon juices from Sicilian cultivars. | 2003 | J. Agric. Food Chem. | pmid:12769519 |
MartÃnez-Richa A and Joseph-Nathan P | Carbon-13 CP-MAS nuclear magnetic resonance studies of teas. | 2003 | Solid State Nucl Magn Reson | pmid:12763559 |
Gleye C et al. | Acaricidal activity of tonka bean extracts. Synthesis and structure-activity relationships of bioactive derivatives. | 2003 | J. Nat. Prod. | pmid:12762809 |
Tombola F et al. | Plant polyphenols inhibit VacA, a toxin secreted by the gastric pathogen Helicobacter pylori. | 2003 | FEBS Lett. | pmid:12753930 |
Suzuki R et al. | Two flavone C-glycosides from the style of Zea mays with glycation inhibitory activity. | 2003 | J. Nat. Prod. | pmid:12713418 |
Gafner S et al. | Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora. | 2003 | J. Nat. Prod. | pmid:12713409 |
Selloum L et al. | Anti-inflammatory effect of rutin on rat paw oedema, and on neutrophils chemotaxis and degranulation. | 2003 | Exp. Toxicol. Pathol. | pmid:12710715 |
Boué SM et al. | Identification of flavone aglycones and glycosides in soybean pods by liquid chromatography-tandem mass spectrometry. | 2003 | J Chromatogr A | pmid:12703901 |
Rustin GJ et al. | 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a novel antivascular agent: phase I clinical and pharmacokinetic study. | 2003 | Br. J. Cancer | pmid:12698178 |
Schauber J et al. | Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. | 2003 | Gut | pmid:12692061 |
Pepper C et al. | Flavopiridol induces apoptosis in B-cell chronic lymphocytic leukaemia cells through a p38 and ERK MAP kinase-dependent mechanism. | 2003 | Leuk. Lymphoma | pmid:12688354 |
Vaher M and Koel M | Separation of polyphenolic compounds extracted from plant matrices using capillary electrophoresis. | 2003 | J Chromatogr A | pmid:12685601 |
López-Lázaro M | Flavonoids as anticancer agents: structure-activity relationship study. | 2002 | Curr Med Chem Anticancer Agents | pmid:12678721 |
Kang KW et al. | Activation of CCAAT/enhancer-binding protein beta by 2'-amino-3'-methoxyflavone (PD98059) leads to the induction of glutathione S-transferase A2. | 2003 | Carcinogenesis | pmid:12663507 |
Fukui Y et al. | A rationale for the shift in colour towards blue in transgenic carnation flowers expressing the flavonoid 3',5'-hydroxylase gene. | 2003 | Phytochemistry | pmid:12657292 |
Wu SN et al. | Differential effects of quercetin, a natural polyphenolic flavonoid, on L-type calcium current in pituitary tumor (GH3) cells and neuronal NG108-15 cells. | 2003 | J. Cell. Physiol. | pmid:12652656 |
Caci E et al. | CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12651632 |
Reddy MK et al. | A flavone and an unusual 23-carbon terpenoid from Andrographis paniculata. | 2003 | Phytochemistry | pmid:12648550 |
Zhou JG et al. | Species-specific transcriptional activity of synthetic flavonoids in guinea pig and mouse cells as a result of differential activation of the aryl hydrocarbon receptor to interact with dioxin-responsive elements. | 2003 | Mol. Pharmacol. | pmid:12644593 |