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Pharmacodynamics and causes of dose-dependent pharmacokinetics of flavone-8-acetic acid (LM-975; NSC-347512) in mice. |
1989 |
Cancer Chemother. Pharmacol. |
pmid:2597279
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Ching LM and Baguley BC |
Reduction of cytotoxic effector cell activity in colon 38 tumours following treatment with flavone acetic acid. |
1989 |
Eur J Cancer Clin Oncol |
pmid:2597283
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Baguley BC et al. |
Comparison of the effects of flavone acetic acid, fostriecin, homoharringtonine and tumour necrosis factor alpha on colon 38 tumours in mice. |
1989 |
Eur J Cancer Clin Oncol |
pmid:2702981
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Lewis CR et al. |
Autonomic neuropathy following treatment with flavone acetic acid. |
1989 |
Eur J Cancer Clin Oncol |
pmid:2703010
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Nagai T et al. |
Inhibition of mouse liver sialidase by plant flavonoids. |
1989 |
Biochem. Biophys. Res. Commun. |
pmid:2775264
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Sun JR and Brown JM |
Enhancement of the antitumor effect of flavone acetic acid by the bioreductive cytotoxic drug SR 4233 in a murine carcinoma. |
1989 |
Cancer Res. |
pmid:2790784
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Cassidy J et al. |
Could interspecies differences in the protein binding of flavone acetic acid contribute to the failure to predict lack of efficacy in patients? |
1989 |
Cancer Chemother. Pharmacol. |
pmid:2713962
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Ertan R et al. |
Synthesis of new annellated flavonoid derivatives possessing spasmolytic activity--VII. |
1989 |
Arch. Pharm. (Weinheim) |
pmid:2751412
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Chabot GG et al. |
Flavone acetic acid (LM-975; NSC-347512) activation to cytotoxic species in vivo and in vitro. |
1989 |
Cancer Chemother. Pharmacol. |
pmid:2758556
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Cummings J et al. |
Characterization of the major metabolites of flavone acetic acid and comparison of their disposition in humans and mice. |
1989 |
Cancer Res. |
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Bibby MC et al. |
Influence of site on the chemosensitivity of transplantable murine colon tumours to flavone acetic acid (LM975, NSC 347512). |
1989 |
Cancer Chemother. Pharmacol. |
pmid:2731316
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Lee DW and Park KH |
Testosterone metabolism by microsomal cytochrome P-450 in liver of rats treated with some inducers. |
1989 |
Int. J. Biochem. |
pmid:2502444
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Urba WJ et al. |
Enhancement of natural killer activity in human peripheral blood by flavone acetic acid. |
1988 |
J. Natl. Cancer Inst. |
pmid:2452890
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Weiss GR et al. |
New anticancer agents. |
1988 |
Cancer Chemother Biol Response Modif |
pmid:2484323
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Hornung RL et al. |
Augmentation of natural killer activity, induction of IFN and development tumor immunity during the successful treatment of established murine renal cancer using flavone acetic acid and IL-2. |
1988 |
J. Immunol. |
pmid:2460546
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Verweij J et al. |
Rapid alkalinisation for flavone acetic acid administration: a potentially hazardous procedure. |
1988 |
Lancet |
pmid:2893206
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Davis HP et al. |
Immune thrombocytopenia caused by flavone-8-acetic acid. |
1988 |
Lancet |
pmid:2893207
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Yamazoe Y et al. |
Metabolic activation of a protein pyrolysate promutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by rat liver microsomes and purified cytochrome P-450. |
1988 |
Carcinogenesis |
pmid:3121205
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Yamazoe Y et al. |
Metabolic activation of pyrolysate arylamines by human liver microsomes; possible involvement of a P-488-H type cytochrome P-450. |
1988 |
Jpn. J. Cancer Res. |
pmid:3147272
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Armand J et al. |
Flavonoids: a new class of anticancer agents? Preclinical and clinical data of flavone acetic acid. |
1988 |
Prog. Clin. Biol. Res. |
pmid:3051027
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Pratesi G et al. |
Response of chemically induced primary colon tumours of the mouse to flavone acetic acid (NSC 347 512). |
1988 |
Br. J. Cancer |
pmid:3166904
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Weiss RB et al. |
Phase I and clinical pharmacology study of intravenous flavone acetic acid (NSC 347512). |
1988 |
Cancer Res. |
pmid:3167843
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Bibby MC et al. |
Experimental anti-tumor effects of flavone acetic acid (LM975). |
1988 |
Prog. Clin. Biol. Res. |
pmid:3174695
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Bibby MC et al. |
Unique chemosensitivity of MAC 16 tumours to flavone acetic acid (LM975, NSC 347512). |
1988 |
Br. J. Cancer |
pmid:3179187
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Ching LM and Baguley BC |
Enhancement of in vitro cytotoxicity of mouse peritoneal exudate cells by flavone acetic acid (NSC 347512). |
1988 |
Eur J Cancer Clin Oncol |
pmid:3181272
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Damia G et al. |
Dose-dependent pharmacokinetics of flavone acetic acid in mice. |
1988 |
Cancer Chemother. Pharmacol. |
pmid:3396145
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Evelhoch JL et al. |
Flavone acetic acid (NSC 347512)-induced modulation of murine tumor physiology monitored by in vivo nuclear magnetic resonance spectroscopy. |
1988 |
Cancer Res. |
pmid:3409216
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Gouyette A et al. |
Flavone acetic acid: a nonlinear pharmacokinetic model. |
1988 |
Cancer Chemother. Pharmacol. |
pmid:3409441
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Abdalla S et al. |
Effects of hispidulin, a flavone isolated from Inula viscosa, on isolated guinea-pig smooth muscle. |
1988 |
Gen. Pharmacol. |
pmid:3410278
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Hornung RL et al. |
Immunomodulation of natural killer cell activity by flavone acetic acid: occurrence via induction of interferon alpha/beta. |
1988 |
J. Natl. Cancer Inst. |
pmid:3418728
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Oberpichler H et al. |
Effects of Ginkgo biloba constituents related to protection against brain damage caused by hypoxia. |
1988 |
Pharmacol Res Commun |
pmid:3420139
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Bissery MC et al. |
Flavone acetic acid (NSC 347512)-induced DNA damage in Glasgow osteogenic sarcoma in vivo. |
1988 |
Cancer Res. |
pmid:3422592
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Finlay GJ et al. |
Effect of flavone acetic acid on Lewis lung carcinoma: evidence for an indirect effect. |
1988 |
J. Natl. Cancer Inst. |
pmid:3351960
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Giavazzi R et al. |
Response to flavone acetic acid (NSC 347512) of primary and metastatic human colorectal carcinoma xenografts. |
1988 |
Br. J. Cancer |
pmid:3355765
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Gachályi A et al. |
Mobilization of 85Sr by flavone derivatives (morin and ipriflavone) in normal and pregnant rats. |
1988 |
Radiobiol Radiother (Berl) |
pmid:3186955
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Chen JC et al. |
[Anti-arrhythmic action of 4'-methyl-7-([2-hydroxy-3-(beta-propinamidoethyl)amino]propoxy) flavone hydrochloride (SIPI-644)]. |
1988 |
Zhongguo Yao Li Xue Bao |
pmid:3188948
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Fisher RF et al. |
Specific binding of proteins from Rhizobium meliloti cell-free extracts containing NodD to DNA sequences upstream of inducible nodulation genes. |
1988 |
Genes Dev. |
pmid:3288541
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Hayashi T et al. |
A cytotoxic flavone from Scoparia dulcis L. |
1988 |
Chem. Pharm. Bull. |
pmid:3246045
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Abbiati GA et al. |
Receptor binding studies of the flavone, REC 15/2053, and other bladder spasmolytics. |
1988 |
Pharm. Res. |
pmid:3247311
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Wiltrout RH et al. |
Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer. |
1988 |
J. Immunol. |
pmid:3258894
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Rabinovitz M |
The structure of flavone-8-acetic acid, a chemotherapeutic agent, and its application to drug design. |
1988 |
J. Enzym. Inhib. |
pmid:3236069
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Robbins RC |
Flavones in citrus exhibit antiadhesive action on platelets. |
1988 |
Int J Vitam Nutr Res |
pmid:3243696
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Armitage JP et al. |
Comparison of the chemotactic behaviour of Rhizobium leguminosarum with and without the nodulation plasmid. |
1988 |
Mol. Microbiol. |
pmid:3210967
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Bourdillat B et al. |
Mechanism of action of hispidulin, a natural flavone, on human platelets. |
1988 |
Prog. Clin. Biol. Res. |
pmid:2845433
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Gao F et al. |
Sesquiterpene lactones and flavonoids from Helianthus species. |
1987 Jan-Feb |
J. Nat. Prod. |
pmid:3598595
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Rubin J et al. |
Flavone-8-acetic acid inhibits ristocetin-induced platelet agglutination and prolongs bleeding time. |
1987 |
Lancet |
pmid:2889983
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Dodion P et al. |
Sensitivity of normal human bone marrow myeloid progenitor cells to anthracycline, cisplatin, anthracene and flavone acetic acid derivatives, and its relevance for the prediction of human plasma concentrations of anticancer drugs. |
1987 |
Eur J Cancer Clin Oncol |
pmid:3436354
|
Ching LM and Baguley BC |
Induction of natural killer cell activity by the antitumour compound flavone acetic acid (NSC 347 512). |
1987 |
Eur J Cancer Clin Oncol |
pmid:3665989
|
Abdalla SS and Abu Zarga MH |
Effects of cirsimaritin, a flavone isolated from Artemisia judaica, on isolated guinea-pig ileum. |
1987 |
Planta Med. |
pmid:3671552
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Kerr DJ et al. |
Phase I and pharmacokinetic study of flavone acetic acid. |
1987 |
Cancer Res. |
pmid:3677106
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