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The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux. |
2006 |
Eur J Pharm Sci |
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Feng Y et al. |
Iridoid glucosides and flavones from the aerial parts of Avicennia marina. |
2006 |
Chem. Biodivers. |
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Kim JH et al. |
Characterization of flavonoid 7-O-glucosyltransferase from Arabidopsis thaliana. |
2006 |
Biosci. Biotechnol. Biochem. |
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Cytisus scoparius link--a natural antioxidant. |
2006 |
BMC Complement Altern Med |
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Anti-inflammatory activity of 5-O-demethylnobiletin, a polymethoxyflavone isolated from Sideritis tragoriganum. |
2006 |
Planta Med. |
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Tsuji PA et al. |
Accumulation and metabolism of the anticancer flavonoid 5,7-dimethoxyflavone compared to its unmethylated analog chrysin in the Atlantic killifish. |
2006 |
Chem. Biol. Interact. |
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Bandyopadhyay S et al. |
Attenuation of osteoclastogenesis and osteoclast function by apigenin. |
2006 |
Biochem. Pharmacol. |
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Ferrer-Sueta G et al. |
Reduction of manganese porphyrins by flavoenzymes and submitochondrial particles: a catalytic cycle for the reduction of peroxynitrite. |
2006 |
Free Radic. Biol. Med. |
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Kim SK et al. |
The mitogen-activated protein kinase kinase (mek) inhibitor PD98059 elevates primary cultured rat hepatocyte glutathione levels independent of inhibiting mek. |
2006 |
Drug Metab. Dispos. |
pmid:16443668
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Lotito SB and Frei B |
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism. |
2006 |
J. Biol. Chem. |
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[Effects of Pollen Typhae total flavone on glucose and lipid metabolism in 3T3-L1 adipocytes]. |
2006 |
Zhong Xi Yi Jie He Xue Bao |
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[Simultaneous determination of total flavone and total saponin in Gynostemma pentaphyllum by signal multiplier spectrophotometry]. |
2006 |
Guang Pu Xue Yu Guang Pu Fen Xi |
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Sato S et al. |
Total synthesis of three naturally occurring 6,8-di-C-glycosylflavonoids: phloretin, naringenin, and apigenin bis-C-beta-D-glucosides. |
2006 |
Carbohydr. Res. |
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Cheng XP et al. |
Inhibitory effect of total flavone of Abelmoschus manihot L. Medic on NMDA receptor-mediated current in cultured rat hippocampal neurons. |
2006 |
Neurosci. Res. |
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Herath W et al. |
Microbial metabolism. Part 6. Metabolites of 3- and 7-hydroxyflavones. |
2006 |
Chem. Pharm. Bull. |
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Molecular interactions between human cytochrome P450 1A2 and flavone derivatives. |
2006 |
Med Chem |
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Tumor inhibition and improved immunity in mice treated with flavone from Cirsium japonicum DC. |
2006 |
Int. Immunopharmacol. |
pmid:16846832
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Synthesis and immunosuppressive activity of L-rhamnopyranosyl flavonoids. |
2006 |
Org. Biomol. Chem. |
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Stipcevic T et al. |
Effect of different flavonoids on collagen synthesis in human fibroblasts. |
2006 |
Plant Foods Hum Nutr |
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Gupta A et al. |
Influence of sea buckthorn (Hippophae rhamnoides L.) flavone on dermal wound healing in rats. |
2006 |
Mol. Cell. Biochem. |
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Ullah Mughal E et al. |
Synthesis and antibacterial activity of substituted flavones, 4-thioflavones and 4-iminoflavones. |
2006 |
Bioorg. Med. Chem. |
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Caddick S et al. |
Synthetic ligands for apo-neocarzinostatin. |
2006 |
J. Am. Chem. Soc. |
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Qi S et al. |
Simultaneous determination of bioactive flavone derivatives in Chinese herb extraction by capillary electrophoresis used different electrolyte systems--borate and ionic liquids. |
2006 |
J Chromatogr A |
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Xanthine oxidase inhibitors from the flowers of Chrysanthemum sinense. |
2006 |
Planta Med. |
pmid:16450295
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Sandabe UK et al. |
Phytochemical screening and effect of aqueous extract of Ficus sycomorus L. (Moraceae) stem bark on muscular activity in laboratory animals. |
2006 |
J Ethnopharmacol |
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Sun JL et al. |
Immunologic enhancement of compound Chinese herbal medicinal ingredients and their efficacy comparison with compound Chinese herbal medicines. |
2006 |
Vaccine |
pmid:16378665
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Wurglics M and Schubert-Zsilavecz M |
Hypericum perforatum: a 'modern' herbal antidepressant: pharmacokinetics of active ingredients. |
2006 |
Clin Pharmacokinet |
pmid:16640452
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Moon BH et al. |
Complete assignment of (1)H and (13)C NMR data of dihydroxyflavone derivatives. |
2006 |
Magn Reson Chem |
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Sandabe UK et al. |
Phytochemical screening and effect of aqueous extract of Ficus sycomorus L. (Moraceae) stembark on muscular activity in laboratory animals. |
2006 |
J Ethnopharmacol |
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Hamada M et al. |
TCDD-induced CYP1A1 expression, an index of dioxin toxicity, is suppressed by flavonoids permeating the human intestinal Caco-2 cell monolayers. |
2006 |
J. Agric. Food Chem. |
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González B et al. |
Respiratory system of Gluconacetobacter diazotrophicus PAL5. Evidence for a cyanide-sensitive cytochrome bb and cyanide-resistant cytochrome ba quinol oxidases. |
2006 |
Biochim. Biophys. Acta |
pmid:16934215
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Zhou JM et al. |
Sequential O-methylation of tricetin by a single gene product in wheat. |
2006 |
Biochim. Biophys. Acta |
pmid:16730127
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Kim BG et al. |
Regioselectivity of 7-O-methyltransferase of poplar to flavones. |
2006 |
J. Biotechnol. |
pmid:16713650
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Capasso R et al. |
Inhibition of rat vas deferens contractions by flavonoids in-vitro. |
2006 |
J. Pharm. Pharmacol. |
pmid:16536906
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Meyer H et al. |
Bioavailability of apigenin from apiin-rich parsley in humans. |
2006 |
Ann. Nutr. Metab. |
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Schutte ME et al. |
An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers. |
2006 |
Toxicol. Appl. Pharmacol. |
pmid:16997339
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Mavel S et al. |
Synthesis and biological evaluation of a series of flavone derivatives as potential radioligands for imaging the multidrug resistance-associated protein 1 (ABCC1/MRP1). |
2006 |
Bioorg. Med. Chem. |
pmid:16263302
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Verschoyle RD et al. |
Preliminary safety evaluation of the putative cancer chemopreventive agent tricin, a naturally occurring flavone. |
2006 |
Cancer Chemother. Pharmacol. |
pmid:16001171
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Stintzing FC et al. |
Thermal degradation kinetics of isoflavone aglycones from soy and red clover. |
2006 |
Mol Nutr Food Res |
pmid:16598813
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Lee MH et al. |
Bioactive constituents of Spatholobus suberectus in regulating tyrosinase-related proteins and mRNA in HEMn cells. |
2006 |
Phytochemistry |
pmid:16782143
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Chemler JA et al. |
Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae. |
2006 |
Microb. Cell Fact. |
pmid:16719921
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Expression of a soluble flavone synthase allows the biosynthesis of phytoestrogen derivatives in Escherichia coli. |
2006 |
Appl. Microbiol. Biotechnol. |
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Sagar SM et al. |
Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 1. |
2006 |
Curr Oncol |
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Leishmania donovani: intracellular ATP level regulates apoptosis-like death in luteolin induced dyskinetoplastid cells. |
2006 |
Exp. Parasitol. |
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Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. |
2006 |
J. Mol. Graph. Model. |
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Kostova I et al. |
Structure-Activity Relationships of Synthetic Coumarins as HIV-1 Inhibitors. |
2006 |
Bioinorg Chem Appl |
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Opassiri R et al. |
Analysis of rice glycosyl hydrolase family 1 and expression of Os4bglu12 beta-glucosidase. |
2006 |
BMC Plant Biol. |
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Anti-inflammatory activity of the synthetic C-C biflavonoids. |
2006 |
J. Pharm. Pharmacol. |
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Lévy V et al. |
A phase I dose-finding and pharmacokinetic study of subcutaneous semisynthetic homoharringtonine (ssHHT) in patients with advanced acute myeloid leukaemia. |
2006 |
Br. J. Cancer |
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Apigenin-induced-apoptosis is mediated by the activation of PKCdelta and caspases in leukemia cells. |
2006 |
Biochem. Pharmacol. |
pmid:16844095
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Inhibition of intestinal carcinogenesis by a new flavone derivative, chafuroside, in oolong tea. |
2006 |
Cancer Sci. |
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Bradshaw PC and Pfeiffer DR |
Loss of NAD(H) from swollen yeast mitochondria. |
2006 |
BMC Biochem. |
pmid:16433924
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Carrara M et al. |
Mono- or di-fluorinated analogues of flavone-8-acetic acid: synthesis and in vitro biological activity. |
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Anticancer Res. |
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Kanho H et al. |
Biotransformation of benzaldehyde-type and acetophenone-type derivatives by Pharbitis nil hairy roots. |
2005 |
Chem. Pharm. Bull. |
pmid:15802832
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Fernández SP et al. |
Synergistic interaction between hesperidin, a natural flavonoid, and diazepam. |
2005 |
Eur. J. Pharmacol. |
pmid:15840404
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Yoon JH and Baek SJ |
Molecular targets of dietary polyphenols with anti-inflammatory properties. |
2005 |
Yonsei Med. J. |
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[Study on extraction of zhuyun 3# by supercritical CO2]. |
2005 |
Zhong Yao Cai |
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Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro. |
2005 |
J. Med. Chem. |
pmid:15658870
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Ebert B et al. |
Induction of phase-1 metabolizing enzymes by oltipraz, flavone and indole-3-carbinol enhance the formation and transport of benzo[a]pyrene sulfate conjugates in intestinal Caco-2 cells. |
2005 |
Toxicol. Lett. |
pmid:15890477
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Erhart LM et al. |
Flavone initiates a hierarchical activation of the caspase-cascade in colon cancer cells. |
2005 |
Apoptosis |
pmid:15909122
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Nakagawa-Goto K et al. |
Total synthesis and bioactivity of unique flavone desmosdumotin B and its analogs. |
2005 |
Bioorg. Med. Chem. Lett. |
pmid:15913998
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Wang TC et al. |
Synthesis, antiproliferative, and antiplatelet activities of oxime- and methyloxime-containing flavone and isoflavone derivatives. |
2005 |
Bioorg. Med. Chem. |
pmid:15990314
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Wang TC et al. |
Synthesis, and cytotoxic and antiplatelet activities of oxime- and methyloxime-containing flavone, isoflavone, and xanthone derivatives. |
2005 |
Chem. Biodivers. |
pmid:17191978
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Horvath CR et al. |
Identification and quantification of eight flavones in root and shoot tissues of the medicinal plant huang-qin (Scutellaria baicalensis Georgi) using high-performance liquid chromatography with diode array and mass spectrometric detection. |
2005 |
J Chromatogr A |
pmid:15679157
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Cappelli C et al. |
Computational study of conformational and chiroptical properties of (2R,3S,4R)-(+)-3,3',4,4',7-flavanpentol. |
2005 |
Chirality |
pmid:16196026
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Martens S and Mithöfer A |
Flavones and flavone synthases. |
2005 |
Phytochemistry |
pmid:16137727
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Wenzel U et al. |
Increased mitochondrial palmitoylcarnitine/carnitine countertransport by flavone causes oxidative stress and apoptosis in colon cancer cells. |
2005 |
Cell. Mol. Life Sci. |
pmid:16314920
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Cong Y et al. |
A new flavonoside from Leonurus heterophyllus. |
2005 |
J Asian Nat Prod Res |
pmid:15621638
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Singh RP et al. |
Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: structure-activity relationship with linarin and linarin acetate. |
2005 |
Carcinogenesis |
pmid:15637089
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Melidou M et al. |
Protection against nuclear DNA damage offered by flavonoids in cells exposed to hydrogen peroxide: the role of iron chelation. |
2005 |
Free Radic. Biol. Med. |
pmid:16298684
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Radioiodinated flavones for in vivo imaging of beta-amyloid plaques in the brain. |
2005 |
J. Med. Chem. |
pmid:16279784
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Wang F et al. |
Neuroactive flavonoids interacting with GABAA receptor complex. |
2005 |
Curr Drug Targets CNS Neurol Disord |
pmid:16266290
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Kim H et al. |
Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid. |
2005 |
J. Agric. Food Chem. |
pmid:16248550
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Kovacic P |
Fundamental, electron transfer mechanism by pyrylium-type ions for the anticancer drugs 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA). |
2005 |
Curr Med Chem Anticancer Agents |
pmid:16178775
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Ozbey S et al. |
Antibacterial 4-amino-N-(5-methylisoxazol-3-yl)-N-[(4-oxo-2-phenyl-4H-1-benzopyran-6-yl)methyl]benzenesulfonamide. |
2005 |
Acta Crystallogr C |
pmid:16143780
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Huong DT et al. |
A new flavone and cytotoxic activity of flavonoid constituents isolated from Miliusa balansae (Annonaceae). |
2005 |
Pharmazie |
pmid:16124409
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Woodman OL et al. |
Vasorelaxant and antioxidant activity of flavonols and flavones: structure-activity relationships. |
2005 |
J. Cardiovasc. Pharmacol. |
pmid:16116335
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Shiono M et al. |
Phytochemistry: structure of the blue cornflower pigment. |
2005 |
Nature |
pmid:16094358
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Han Y |
Ginkgo terpene component has an anti-inflammatory effect on Candida albicans-caused arthritic inflammation. |
2005 |
Int. Immunopharmacol. |
pmid:15829420
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Sawada Y and Ayabe S |
Multiple mutagenesis of P450 isoflavonoid synthase reveals a key active-site residue. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15809082
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Malolanarasimhan K et al. |
Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe. |
2005 |
Bioorg. Med. Chem. |
pmid:15781383
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Ngadjui BT et al. |
Prenylated chalcones, flavone and other constituents of the twigs of Dorstenia angusticornis and Dorstenia barteri var. subtriangularis. |
2005 |
Phytochemistry |
pmid:15771891
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Zhang J and Brodbelt JS |
Silver complexation and tandem mass spectrometry for differentiation of isomeric flavonoid diglycosides. |
2005 |
Anal. Chem. |
pmid:15762583
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Göker H et al. |
Synthesis and potent antimicrobial activity of some novel 2-phenyl or methyl-4H-1-benzopyran-4-ones carrying amidinobenzimidazoles. |
2005 |
Bioorg. Med. Chem. |
pmid:15698788
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Schütz K et al. |
Characterization of phenolic acids and flavonoids in dandelion (Taraxacum officinale WEB. ex WIGG.) root and herb by high-performance liquid chromatography/electrospray ionization mass spectrometry. |
2005 |
Rapid Commun. Mass Spectrom. |
pmid:15593267
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Nagai S et al. |
Kinetic study of the quenching reaction of singlet oxygen by flavonoids in ethanol solution. |
2005 |
J Phys Chem B |
pmid:16851486
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Likhitwitayawuid K et al. |
Phenolics with antiviral activity from Millettia erythrocalyx and Artocarpus lakoocha. |
2005 |
Nat. Prod. Res. |
pmid:15715263
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Furuya H et al. |
Some flavonoids and DHEA-S prevent the cis-effect of expanded CTG repeats in a stable PC12 cell transformant. |
2005 |
Biochem. Pharmacol. |
pmid:15652241
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Wenzig E et al. |
Flavonolignans from Avena sativa. |
2005 |
J. Nat. Prod. |
pmid:15730266
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Cai H et al. |
The rice bran constituent tricin potently inhibits cyclooxygenase enzymes and interferes with intestinal carcinogenesis in ApcMin mice. |
2005 |
Mol. Cancer Ther. |
pmid:16170019
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Takeda K et al. |
Components of protocyanin, a blue pigment from the blue flowers of Centaurea cyanus. |
2005 |
Phytochemistry |
pmid:16005311
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Garritano S et al. |
Assessment of estrogenic activity of flavonoids from Mediterranean plants using an in vitro short-term test. |
2005 |
Phytomedicine |
pmid:15693722
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Girish KS and Kemparaju K |
Inhibition of Naja naja venom hyaluronidase by plant-derived bioactive components and polysaccharides. |
2005 |
Biochemistry Mosc. |
pmid:16212553
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Ahmed-Belkacem A et al. |
Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2. |
2005 |
Cancer Res. |
pmid:15930306
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UydeÅŸ-DoÄŸan BS et al. |
The comparison of the relaxant effects of two methoxylated flavones in rat aortic rings. |
2005 |
Vascul. Pharmacol. |
pmid:16169284
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Simons AL et al. |
Human gut microbial degradation of flavonoids: structure-function relationships. |
2005 |
J. Agric. Food Chem. |
pmid:15884869
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Chi YS and Kim HP |
Suppression of cyclooxygenase-2 expression of skin fibroblasts by wogonin, a plant flavone from Scutellaria radix. |
2005 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:15589400
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Lu H et al. |
Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin. |
2005 |
J. Med. Chem. |
pmid:15689157
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Capodice JL et al. |
Complementary and alternative medicine for chronic prostatitis/chronic pelvic pain syndrome. |
2005 |
Evid Based Complement Alternat Med |
pmid:16322807
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Xie F et al. |
The osteoprotective effect of Herba epimedii (HEP) extract in vivo and in vitro. |
2005 |
Evid Based Complement Alternat Med |
pmid:16136213
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