Cabrera M et al. |
Identification of chalcones as in vivo liver monofunctional phase II enzymes inducers. |
2010 |
Bioorg. Med. Chem. |
pmid:20639112
|
Chen IL et al. |
Synthesis and antiproliferative evaluation of amide-containing flavone and isoflavone derivatives. |
2008 |
Bioorg. Med. Chem. |
pmid:18662883
|
Lin YM et al. |
Chalcones and flavonoids as anti-tuberculosis agents. |
2002 |
Bioorg. Med. Chem. |
pmid:12057669
|
Cabrera M et al. |
Synthetic chalcones, flavanones, and flavones as antitumoral agents: biological evaluation and structure-activity relationships. |
2007 |
Bioorg. Med. Chem. |
pmid:17383189
|
Golub AG et al. |
Discovery and characterization of synthetic 4'-hydroxyflavones-New CK2 inhibitors from flavone family. |
2013 |
Bioorg. Med. Chem. |
pmid:24011954
|
Kuemmerle J et al. |
Synthesis of caged 2,3,3a,7a-tetrahydro-3,6-methanobenzofuran-7(6H)-ones: Evaluating the minimum structure for apoptosis induction by gambogic acid. |
2008 |
Bioorg. Med. Chem. |
pmid:18337106
|
Springsteel MF et al. |
Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain. |
2003 |
Bioorg. Med. Chem. |
pmid:12927873
|
Betti L et al. |
Design, synthesis, and alpha(1)-adrenoceptor binding properties of new arylpiperazine derivatives bearing a flavone nucleus as the terminal heterocyclic molecular portion. |
2004 |
Bioorg. Med. Chem. |
pmid:15018926
|
Ono M et al. |
Synthesis and characterization of styrylchromone derivatives as beta-amyloid imaging agents. |
2007 |
Bioorg. Med. Chem. |
pmid:17035032
|
Kubo I et al. |
Flavonols from Heterotheca inuloides: tyrosinase inhibitory activity and structural criteria. |
2000 |
Bioorg. Med. Chem. |
pmid:10976523
|
Ullah Mughal E et al. |
Synthesis and antibacterial activity of substituted flavones, 4-thioflavones and 4-iminoflavones. |
2006 |
Bioorg. Med. Chem. |
pmid:16603364
|
Dong X et al. |
Identification of SVM-based classification model, synthesis and evaluation of prenylated flavonoids as vasorelaxant agents. |
2008 |
Bioorg. Med. Chem. |
pmid:18678502
|
Iori F et al. |
Theoretical quantitative structure-activity relationships of flavone ligands interacting with cytochrome P450 1A1 and 1A2 isozymes. |
2005 |
Bioorg. Med. Chem. |
pmid:15914008
|
Marder M et al. |
Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABA(A) receptor complex. |
2001 |
Bioorg. Med. Chem. |
pmid:11249125
|
Lewin G et al. |
Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
2011 |
Bioorg. Med. Chem. |
pmid:21146994
|
Li HQ et al. |
Synthesis of C(7) modified chrysin derivatives designing to inhibit beta-ketoacyl-acyl carrier protein synthase III (FabH) as antibiotics. |
2009 |
Bioorg. Med. Chem. |
pmid:19664929
|
Lewin G et al. |
Influence of the skeleton on the cytotoxicity of flavonoids. |
2012 |
Bioorg. Med. Chem. |
pmid:22257529
|
Liu H et al. |
New synthetic flavone derivatives induce apoptosis of hepatocarcinoma cells. |
2010 |
Bioorg. Med. Chem. |
pmid:20674374
|
Wang SQ et al. |
Flavonoids from Dracocephalum tanguticum and their cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20932762
|
Nilsson J et al. |
Azaflavones compared to flavones as ligands to the benzodiazepine binding site of brain GABA(A) receptors. |
2008 |
Bioorg. Med. Chem. Lett. |
pmid:18851913
|
Chen WQ et al. |
A new antifungal and cytotoxic C-methylated flavone glycoside from Picea neoveitchii. |
2012 |
Bioorg. Med. Chem. Lett. |
pmid:22901896
|
An JY et al. |
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE2 in LPS-induced RAW 264.7 cells. |
2017 |
Bioorg. Med. Chem. Lett. |
pmid:28408221
|
Nakagawa-Goto K et al. |
Total synthesis and bioactivity of unique flavone desmosdumotin B and its analogs. |
2005 |
Bioorg. Med. Chem. Lett. |
pmid:15913998
|
Auffret G et al. |
Synthesis and antimalarial evaluation of a series of piperazinyl flavones. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17166718
|
Ryu YB et al. |
Structural characteristics of flavanones and flavones from Cudrania tricuspidata for neuraminidase inhibition. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19660948
|
Lebeau J et al. |
Beneficial effects of different flavonoids, on functional recovery after ischemia and reperfusion in isolated rat heart. |
2001 |
Bioorg. Med. Chem. Lett. |
pmid:11140725
|
Balboni G et al. |
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins. |
2012 |
Bioorg. Med. Chem. Lett. |
pmid:22487176
|
Choe H et al. |
Structure-based design of flavone-based inhibitors of wild-type and T315I mutant of ABL. |
2013 |
Bioorg. Med. Chem. Lett. |
pmid:23790540
|
Hyup YH et al. |
2,3-Diarylbenzopyran derivatives as a novel class of selective cyclooxygenase-2 inhibitors. |
2003 |
Bioorg. Med. Chem. Lett. |
pmid:12565941
|
Tamura S et al. |
New inhibitors for expression of IgE receptor on human mast cell. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20202836
|
Kang Y et al. |
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain. |
2017 |
Bioorg. Med. Chem. Lett. |
pmid:28049590
|
Hatnapure GD et al. |
Synthesis and biological evaluation of novel piperazine derivatives of flavone as potent anti-inflammatory and antimicrobial agent. |
2012 |
Bioorg. Med. Chem. Lett. |
pmid:22981334
|
Ahmed N et al. |
Synthesis, characterization, and estrogen receptor binding affinity of flavone-, indole-, and furan-estradiol conjugates. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17379515
|
Shin SY et al. |
Relationship between the structures of flavonoids and their NF-κB-dependent transcriptional activities. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21907578
|
Ono M et al. |
99mTc/Re complexes based on flavone and aurone as SPECT probes for imaging cerebral β-amyloid plaques. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20797860
|
Gao L et al. |
3D QSAR and docking study of flavone derivatives as potent inhibitors of influenza H1N1 virus neuraminidase. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21843936
|
Jin J et al. |
Design, synthesis and biological evaluation of new arylpiperazine derivatives bearing a flavone moiety as α1-adrenoceptor antagonists. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21236664
|
Baxter A et al. |
Non-covalent inhibitors of rhinovirus 3C protease. |
2011 |
Bioorg. Med. Chem. Lett. |
pmid:21183345
|
Liu XH et al. |
Synthesis and molecular docking studies of novel 2-chloro-pyridine derivatives containing flavone moieties as potential antitumor agents. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20538457
|
Aboul-Enein HY et al. |
Scavenging effects of phenolic compounds on reactive oxygen species. |
2007 |
Biopolymers |
pmid:17373654
|
Xu H et al. |
Molecular cloning and characterization of phenylalanine ammonia-lyase, cinnamate 4-hydroxylase and genes involved in flavone biosynthesis in Scutellaria baicalensis. |
2010 |
Bioresour. Technol. |
pmid:20708926
|
Kim JH et al. |
Characterization of flavonoid 7-O-glucosyltransferase from Arabidopsis thaliana. |
2006 |
Biosci. Biotechnol. Biochem. |
pmid:16794327
|
Kanho H et al. |
Glucosylation of phenolic compounds by Pharbitis nil hairy roots: I. Glucosylation of coumarin and flavone derivatives. |
2004 |
Biosci. Biotechnol. Biochem. |
pmid:15502347
|
Ueda H et al. |
A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-alpha production. |
2004 |
Biosci. Biotechnol. Biochem. |
pmid:14745173
|
Han DH et al. |
Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids. |
2002 |
Biosci. Biotechnol. Biochem. |
pmid:12224631
|
Matsui T et al. |
Luteolin, a flavone, does not suppress postprandial glucose absorption through an inhibition of alpha-glucosidase action. |
2002 |
Biosci. Biotechnol. Biochem. |
pmid:12005074
|
Gao H et al. |
Structure-activity relationships for alpha-glucosidase inhibition of baicalein, 5,6,7-trihydroxyflavone: the effect of A-ring substitution. |
2004 |
Biosci. Biotechnol. Biochem. |
pmid:14981300
|
Yun CS et al. |
Expression of parsley flavone synthase I establishes the flavone biosynthetic pathway in Arabidopsis thaliana. |
2008 |
Biosci. Biotechnol. Biochem. |
pmid:18391443
|
Feng XT et al. |
Pollen Typhae total flavone improves insulin resistance in high-fat diet and low-dose streptozotocin-induced type 2 diabetic rats. |
2014 |
Biosci. Biotechnol. Biochem. |
pmid:25273139
|
Watanabe J et al. |
Coumarin and flavone derivatives from estragon and thyme as inhibitors of chemical mediator release from RBL-2H3 Cells. |
2005 |
Biosci. Biotechnol. Biochem. |
pmid:15665459
|
Cao H et al. |
Microbial biotransformation of bioactive flavonoids. |
|
Biotechnol. Adv. |
pmid:25447420
|
Takahashi-Ando N et al. |
A screening system for inhibitors of trichothecene biosynthesis: hydroxylation of trichodiene as a target. |
2008 |
Biotechnol. Lett. |
pmid:18239857
|
Wilczańska-Barska A et al. |
Enhanced accumulation of secondary metabolites in hairy root cultures of Scutellaria lateriflora following elicitation. |
2012 |
Biotechnol. Lett. |
pmid:22639092
|
Park NI et al. |
Enhancement of rutin in Fagopyrum esculentum hairy root cultures by the Arabidopsis transcription factor AtMYB12. |
2012 |
Biotechnol. Lett. |
pmid:22113884
|
Kunnumakkara AB et al. |
Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. |
2007 |
Blood |
pmid:17332240
|
Lee YJ et al. |
Characterization of flavone synthase I from rice. |
2008 |
BMB Rep |
pmid:18304453
|
Bradshaw PC and Pfeiffer DR |
Loss of NAD(H) from swollen yeast mitochondria. |
2006 |
BMC Biochem. |
pmid:16433924
|
Clark ST and Verwoerd WS |
A systems approach to identifying correlated gene targets for the loss of colour pigmentation in plants. |
2011 |
BMC Bioinformatics |
pmid:21849042
|
Zuk M et al. |
Flavonoid engineering of flax potentiate its biotechnological application. |
2011 |
BMC Biotechnol. |
pmid:21276227
|
Lin CH et al. |
Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway. |
2015 |
BMC Cancer |
pmid:26675309
|
Nirmal J et al. |
Evaluation of behavioural and antioxidant activity of Cytisus scoparius Link in rats exposed to chronic unpredictable mild stress. |
2008 |
BMC Complement Altern Med |
pmid:18435835
|
Sundararajan R et al. |
Cytisus scoparius link--a natural antioxidant. |
2006 |
BMC Complement Altern Med |
pmid:16542432
|
Duraipandiyan V et al. |
Antimicrobial activity of sesquiterpene lactones isolated from traditional medicinal plant, Costus speciosus (Koen ex.Retz.) Sm. |
2012 |
BMC Complement Altern Med |
pmid:22397713
|
Chantarudee A et al. |
Chemical constituents and free radical scavenging activity of corn pollen collected from Apis mellifera hives compared to floral corn pollen at Nan, Thailand. |
2012 |
BMC Complement Altern Med |
pmid:22513008
|
Elmann A et al. |
Anti-neuroinflammatory effects of the extract of Achillea fragrantissima. |
2011 |
BMC Complement Altern Med |
pmid:22018032
|
Wang YZ et al. |
In vivo effects of Pain Relieving Plaster on closed soft tissue injury in rabbit ears. |
2008 |
BMC Complement Altern Med |
pmid:18793392
|
Picon PD et al. |
Randomized clinical trial of a phytotherapic compound containing Pimpinella anisum, Foeniculum vulgare, Sambucus nigra, and Cassia augustifolia for chronic constipation. |
2010 |
BMC Complement Altern Med |
pmid:20433751
|
Chen S and Li X |
Transposable elements are enriched within or in close proximity to xenobiotic-metabolizing cytochrome P450 genes. |
2007 |
BMC Evol. Biol. |
pmid:17381843
|
Ibanez S et al. |
Plant chemical defence: a partner control mechanism stabilising plant--seed-eating pollinator mutualisms. |
2009 |
BMC Evol. Biol. |
pmid:19887006
|
Luo H et al. |
Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers. |
2011 |
BMC Genomics |
pmid:22369100
|
Barrero RA et al. |
De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes. |
2011 |
BMC Genomics |
pmid:22151917
|
Hu J et al. |
Genome-wide analysis of DNA methylation in photoperiod- and thermo-sensitive male sterile rice Peiai 64S. |
2015 |
BMC Genomics |
pmid:25887533
|
Zamboni A et al. |
Genome-wide microarray analysis of tomato roots showed defined responses to iron deficiency. |
2012 |
BMC Genomics |
pmid:22433273
|
Goettel W and Messing J |
Divergence of gene regulation through chromosomal rearrangements. |
2010 |
BMC Genomics |
pmid:21118519
|
Studholme DJ et al. |
A draft genome sequence and functional screen reveals the repertoire of type III secreted proteins of Pseudomonas syringae pathovar tabaci 11528. |
2009 |
BMC Genomics |
pmid:19703286
|
Horvath DP et al. |
Transcriptome analysis identifies novel responses and potential regulatory genes involved in seasonal dormancy transitions of leafy spurge (Euphorbia esula L.). |
2008 |
BMC Genomics |
pmid:19014493
|
Puckette MC et al. |
Transcriptomic changes induced by acute ozone in resistant and sensitive Medicago truncatula accessions. |
2008 |
BMC Plant Biol. |
pmid:18433496
|
Li D et al. |
Transcriptional profiling of Medicago truncatula under salt stress identified a novel CBF transcription factor MtCBF4 that plays an important role in abiotic stress responses. |
2011 |
BMC Plant Biol. |
pmid:21718548
|
Göpfert JC et al. |
Identification, functional characterization and developmental regulation of sesquiterpene synthases from sunflower capitate glandular trichomes. |
2009 |
BMC Plant Biol. |
pmid:19580670
|
Zhou JM et al. |
Structure-function relationships of wheat flavone O-methyltransferase: Homology modeling and site-directed mutagenesis. |
2010 |
BMC Plant Biol. |
pmid:20670441
|
Sharma M et al. |
Expression of flavonoid 3'-hydroxylase is controlled by P1, the regulator of 3-deoxyflavonoid biosynthesis in maize. |
2012 |
BMC Plant Biol. |
pmid:23113982
|
Guttikonda SK et al. |
Whole genome co-expression analysis of soybean cytochrome P450 genes identifies nodulation-specific P450 monooxygenases. |
2010 |
BMC Plant Biol. |
pmid:21062474
|
Luo H et al. |
Comparison of 454-ESTs from Huperzia serrata and Phlegmariurus carinatus reveals putative genes involved in lycopodium alkaloid biosynthesis and developmental regulation. |
2010 |
BMC Plant Biol. |
pmid:20854695
|
Galla G et al. |
Computational annotation of genes differentially expressed along olive fruit development. |
2009 |
BMC Plant Biol. |
pmid:19852839
|
Heller G et al. |
Transcriptional analysis of Pinus sylvestris roots challenged with the ectomycorrhizal fungus Laccaria bicolor. |
2008 |
BMC Plant Biol. |
pmid:18298811
|
Zabala G et al. |
Transcriptome changes in the phenylpropanoid pathway of Glycine max in response to Pseudomonas syringae infection. |
2006 |
BMC Plant Biol. |
pmid:17083738
|
Opassiri R et al. |
Analysis of rice glycosyl hydrolase family 1 and expression of Os4bglu12 beta-glucosidase. |
2006 |
BMC Plant Biol. |
pmid:17196101
|
Parravicini C et al. |
Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach. |
2010 |
BMC Struct. Biol. |
pmid:20233425
|
NORTHOVER BJ and SUBRAMANIAN G |
A study of possible mediators of inflammatory reactions in the mouse foot. |
1962 |
Br J Pharmacol Chemother |
pmid:14480419
|
Ching LM et al. |
Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice. |
2004 |
Br. J. Cancer |
pmid:14970872
|
Zhao L et al. |
The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice. |
2002 |
Br. J. Cancer |
pmid:12177785
|
Hori K et al. |
A novel combretastatin A-4 derivative, AC7700, strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organs. |
2002 |
Br. J. Cancer |
pmid:12085211
|
Ching LM et al. |
Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid. |
2002 |
Br. J. Cancer |
pmid:12085190
|
Jones DJ et al. |
Characterisation of metabolites of the putative cancer chemopreventive agent quercetin and their effect on cyclo-oxygenase activity. |
2004 |
Br. J. Cancer |
pmid:15292928
|
Peterson J et al. |
Flavonoid intake and breast cancer risk: a case--control study in Greece. |
2003 |
Br. J. Cancer |
pmid:14520456
|
Kerr DJ et al. |
Phase II trials of flavone acetic acid in advanced malignant melanoma and colorectal carcinoma. |
1989 |
Br. J. Cancer |
pmid:2803908
|
Murray JC et al. |
Flavone acetic acid induces a coagulopathy in mice. |
1989 |
Br. J. Cancer |
pmid:2803949
|
Pratesi G et al. |
Response of chemically induced primary colon tumours of the mouse to flavone acetic acid (NSC 347 512). |
1988 |
Br. J. Cancer |
pmid:3166904
|
Giavazzi R et al. |
Response to flavone acetic acid (NSC 347512) of primary and metastatic human colorectal carcinoma xenografts. |
1988 |
Br. J. Cancer |
pmid:3355765
|
Lévy V et al. |
A phase I dose-finding and pharmacokinetic study of subcutaneous semisynthetic homoharringtonine (ssHHT) in patients with advanced acute myeloid leukaemia. |
2006 |
Br. J. Cancer |
pmid:16847470
|