FLAVONE

FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.

Cross Reference

Introduction

To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with FLAVONE?

FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with FLAVONE

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Per page 10 20 50 | Total 32

PubChem Associated disorders and diseases

What pathways are associated with FLAVONE

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with FLAVONE?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with FLAVONE?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with FLAVONE?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with FLAVONE?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with FLAVONE?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Disease model

Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Animal Disease Models

Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with FLAVONE

Download all related citations
Per page 10 20 50 100 | Total 1492
Authors Title Published Journal PubMed Link
Duraipandiyan V et al. Antimicrobial activity of sesquiterpene lactones isolated from traditional medicinal plant, Costus speciosus (Koen ex.Retz.) Sm. 2012 BMC Complement Altern Med pmid:22397713
Fan Y et al. Liposome and epimedium polysaccharide-propolis flavone can synergistically enhance immune effect of vaccine. 2012 Int. J. Biol. Macromol. pmid:22020157
Zhou G and Lv G [Comparative studies on scavenging DPPH free radicals activity of flavone C-glycosides from different parts of Dendrobium officinale]. 2012 Zhongguo Zhong Yao Za Zhi pmid:22993976
Furukawa Y et al. Isolation and characterization of activators of ERK/MAPK from citrus plants. 2012 Int J Mol Sci pmid:22408427
Shi L et al. Gossypin induces G2/M arrest in human malignant glioma U251 cells by the activation of Chk1/Cdc25C pathway. 2012 Cell. Mol. Neurobiol. pmid:21984341
Skizim NJ et al. Metabolic pathways for photobiological hydrogen production by nitrogenase- and hydrogenase-containing unicellular cyanobacteria Cyanothece. 2012 J. Biol. Chem. pmid:22128188
Chung MJ et al. Suppressive effects of Schizandra chinensis Baillon water extract on allergy-related cytokine generation and degranulation in IgE-antigen complex-stimulated RBL-2H3 cells. 2012 Nutr Res Pract pmid:22586497
Lolli G et al. Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight. 2012 Biochemistry pmid:22794353
Zhang T et al. Inhibitory effects and underlying mechanism of 7-hydroxyflavone phosphate ester in HeLa cells. 2012 PLoS ONE pmid:22574207
Lin TY et al. Hispidulin inhibits the release of glutamate in rat cerebrocortical nerve terminals. 2012 Toxicol. Appl. Pharmacol. pmid:22759588