| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Cystitis | D003556 | 23 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Encephalitis | D004660 | 15 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
FLAVONE
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
Cross Reference
Introduction
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with FLAVONE?
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with FLAVONE
PubChem Associated disorders and diseases
What pathways are associated with FLAVONE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with FLAVONE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with FLAVONE?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with FLAVONE?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with FLAVONE?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with FLAVONE?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with FLAVONE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tunçbilek M et al. | Synthesis and antioxidant properties of some new flavone derivatives on lipid peroxidation in the rat liver. | 2000 | Pharmazie | pmid:11828615 |
| Kulevanova S et al. | HPLC identification and determination of flavone aglycones in Helichrysum plicatum DC. (Asteraceae). | 2000 | Pharmazie | pmid:11828624 |
| BozdaÄŸ O et al. | Synthesis and hypoglycemic activity of some new flavone derivatives. 2nd communication: 4'-flavonyl-2,4-thiazolidinediones. | 2000 | Arzneimittelforschung | pmid:10918947 |
| Wenzel U et al. | Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells. | 2000 | Cancer Res. | pmid:10919656 |
| Ramelet AA | Pharmacologic aspects of a phlebotropic drug in CVI-associated edema. | 2000 | Angiology | pmid:10667639 |
| Viola H et al. | 6-Chloro-3'-nitroflavone is a potent ligand for the benzodiazepine binding site of the GABA(A) receptor devoid of intrinsic activity. | 2000 | Pharmacol. Biochem. Behav. | pmid:10672984 |
| da Silva EL et al. | Inhibitory effect of flavonoids on low-density lipoprotein peroxidation catalyzed by mammalian 15-lipoxygenase. | 2000 | IUBMB Life | pmid:10995031 |
| Wollenweber E et al. | Epicuticular flavonoids of some Scrophulariaceae. | 2000 Jan-Feb | Z. Naturforsch., C, J. Biosci. | pmid:10739092 |
| Harris SR et al. | Oxidative stress contributes to the anti-proliferative effects of flavone acetic acid on endothelial cells. | 2000 Jul-Aug | Anticancer Res. | pmid:10953282 |
| Shao ZM et al. | Genistein's "ER-dependent and independent" actions are mediated through ER pathways in ER-positive breast carcinoma cell lines. | 2000 Jul-Aug | Anticancer Res. | pmid:10953303 |
| Duportail G et al. | Neutral fluorescence probe with strong ratiometric response to surface charge of phospholipid membranes. | 2001 | FEBS Lett. | pmid:11718715 |
| Krakauer T et al. | The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines. | 2001 | FEBS Lett. | pmid:11434925 |
| Fabre N et al. | Determination of flavone, flavonol, and flavanone aglycones by negative ion liquid chromatography electrospray ion trap mass spectrometry. | 2001 | J. Am. Soc. Mass Spectrom. | pmid:11401161 |
| Tanaka S et al. | Influence of natural and synthetic compounds on cell surface expression of cell adhesion molecules, ICAM-1 and VCAM-1. | 2001 | Planta Med. | pmid:11301853 |
| Rajendran NN et al. | Modulation by insulin rather than blood glucose of the pain threshold in acute physiological and flavone induced antinociception in mice. | 2001 | Indian J. Exp. Biol. | pmid:11883508 |
| Kim SJ | Effect of biflavones of Ginkgo biloba against UVB-induced cytotoxicity in vitro. | 2001 | J. Dermatol. | pmid:11449670 |
| Chi YS et al. | Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxygenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells. | 2001 | Biochem. Pharmacol. | pmid:11322923 |
| Lim SS et al. | Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues. | 2001 | J. Pharm. Pharmacol. | pmid:11370705 |
| Huang X et al. | 3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors. | 2001 | J. Med. Chem. | pmid:11384234 |
| Velázquez I and Pardo JP | Kinetic characterization of the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae. | 2001 | Arch. Biochem. Biophys. | pmid:11370674 |