FLAVONE

FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.

Cross Reference

Introduction

To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with FLAVONE?

FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with FLAVONE

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Per page 10 20 50 | Total 32

PubChem Associated disorders and diseases

What pathways are associated with FLAVONE

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with FLAVONE?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with FLAVONE?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with FLAVONE?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with FLAVONE?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with FLAVONE?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Disease model

Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Animal Disease Models

Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with FLAVONE

Download all related citations
Per page 10 20 50 100 | Total 1492
Authors Title Published Journal PubMed Link
Kulevanova S et al. HPLC identification and determination of flavone aglycones in Helichrysum plicatum DC. (Asteraceae). 2000 Pharmazie pmid:11828624
Frangne N et al. Flavone glucoside uptake into barley mesophyll and Arabidopsis cell culture vacuoles. Energization occurs by H(+)-antiport and ATP-binding cassette-type mechanisms. 2002 Plant Physiol. pmid:11842175
Fang J and Beattie DS Novel FMN-containing rotenone-insensitive NADH dehydrogenase from Trypanosoma brucei mitochondria: isolation and characterization. 2002 Biochemistry pmid:11863445
Cai H et al. A straightforward means of coupling preparative high-performance liquid chromatography and mass spectrometry. 2002 Rapid Commun. Mass Spectrom. pmid:11870892
Rajendran NN et al. Modulation by insulin rather than blood glucose of the pain threshold in acute physiological and flavone induced antinociception in mice. 2001 Indian J. Exp. Biol. pmid:11883508
Isobe T et al. [Antibacterial constituents against Helicobacter pylori of Brazilian medicinal plant, Pariparoba]. 2002 Yakugaku Zasshi pmid:11968842
Kragh M et al. Acute effects of vascular modifying agents in solid tumors assessed by noninvasive laser Doppler flowmetry and near infrared spectroscopy. 2002 May-Jun Neoplasia pmid:11988846
Matsui T et al. Luteolin, a flavone, does not suppress postprandial glucose absorption through an inhibition of alpha-glucosidase action. 2002 Biosci. Biotechnol. Biochem. pmid:12005074
Hadjokas NE et al. Arginine to lysine 108 substitution in recombinant CYP1A2 abolishes methoxyresorufin metabolism in lymphoblastoid cells. 2002 Br. J. Pharmacol. pmid:12023936
Lin YM et al. Chalcones and flavonoids as anti-tuberculosis agents. 2002 Bioorg. Med. Chem. pmid:12057669
Rawel HM et al. Interactions of different phenolic acids and flavonoids with soy proteins. 2002 Int. J. Biol. Macromol. pmid:12063116
Kuffel MJ et al. Activation of the antitumor agent aminoflavone (NSC 686288) is mediated by induction of tumor cell cytochrome P450 1A1/1A2. 2002 Mol. Pharmacol. pmid:12065765
Jacobson KA et al. Interactions of flavones and other phytochemicals with adenosine receptors. 2002 Adv. Exp. Med. Biol. pmid:12083460
Ching LM et al. Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid. 2002 Br. J. Cancer pmid:12085190
Hori K et al. A novel combretastatin A-4 derivative, AC7700, strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organs. 2002 Br. J. Cancer pmid:12085211
Choi J et al. Flavones from Scutellaria baicalensis Georgi attenuate apoptosis and protein oxidation in neuronal cell lines. 2002 Biochim. Biophys. Acta pmid:12090934
Shimizu E and Ogata Y Activation of bone sialoprotein gene transcription by flavonoids is mediated through an inverted CCAAT box in ROS 17/2.8 cells. 2002 J. Cell. Biochem. pmid:12112014
Blatt CT et al. Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis. 2002 Phytother Res pmid:12112286
Voskresensky ON and Levitsky AP QSAR aspects of flavonoids as a plentiful source of new drugs. 2002 Curr. Med. Chem. pmid:12132993
Marder M and Paladini AC GABA(A)-receptor ligands of flavonoid structure. 2002 Curr Top Med Chem pmid:12171576