| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neoplasms, Experimental | D009374 | 10 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
FLAVONE
FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
Cross Reference
Introduction
To understand associated biological information of FLAVONE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with FLAVONE?
FLAVONE is suspected in Diabetes Mellitus, Non-Insulin-Dependent, Obesity, Chronic Disease, Disintegration, Cardiovascular Diseases, Cerebrovascular accident and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with FLAVONE
PubChem Associated disorders and diseases
What pathways are associated with FLAVONE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with FLAVONE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with FLAVONE?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with FLAVONE?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with FLAVONE?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with FLAVONE?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Disease model
Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Animal Disease Models
Animal Disease Models are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with FLAVONE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Relling MV et al. | Anticancer drugs as inhibitors of two polymorphic cytochrome P450 enzymes, debrisoquin and mephenytoin hydroxylase, in human liver microsomes. | 1989 | Cancer Res. | pmid:2908853 |
| Desoize B et al. | Response of primary tumour, spontaneous metastases and recurrence of Lewis lung carcinoma (3LL) to flavone acetic acid (FAA, LM975). | 1989 Nov-Dec | Anticancer Res. | pmid:2627123 |
| Morita K et al. | Stimulatory actions of bioflavonoids on tyrosine uptake into cultured bovine adrenal chromaffin cells. | 1990 | Biochem. Biophys. Res. Commun. | pmid:1977385 |
| Ibrahim AR and Abul-Hajj YJ | Microbiological transformation of flavone and isoflavone. | 1990 | Xenobiotica | pmid:2346033 |
| Liu H and Wehmeyer KR | Solid-phase extraction with supercritical fluid elution as a sample preparation technique for the ultratrace analysis of flavone in blood plasma. | 1992 | J. Chromatogr. | pmid:1400746 |
| Le Bon AM et al. | Inhibition of microsome-mediated binding of benzo[a]pyrene to DNA by flavonoids either in vitro or after dietary administration to rats. | 1992 | Chem. Biol. Interact. | pmid:1643669 |
| Siess MH et al. | Dietary modification of drug-metabolizing enzyme activities: dose-response effect of flavonoids. | 1992 | J Toxicol Environ Health | pmid:1602520 |
| Minagawa N et al. | Possible involvement of superoxide anion in the induction of cyanide-resistant respiration in Hansenula anomala. | 1992 | FEBS Lett. | pmid:1318225 |
| Barrellier MT | [Lymphedema: is there a treatment?]. | 1992 Jan-Feb | Rev Med Interne | pmid:1410875 |
| Monici M et al. | Flavone photoreactivity. UV-induced reactions in organic solvents and micellar systems. | 1993 | J. Photochem. Photobiol. B, Biol. | pmid:8271117 |
| Valenti P et al. | Benzo-gamma-pyrone analogues of geiparvarin: synthesis and biological evaluation against B16 melanoma cells. | 1993 | Anticancer Drug Des. | pmid:8251042 |
| Liu H and Wehmeyer KR | Supercritical fluid extraction as a sample preparation technique for the direct isolation of drugs from plasma prior to analysis. | 1994 | J. Chromatogr. B, Biomed. Appl. | pmid:7952070 |
| Ching LM et al. | Induction of tumor necrosis factor-alpha messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimethylxanthenone-4-acetic acid (NSC 640488). | 1994 | Cancer Res. | pmid:8313372 |
| Tamura M et al. | Effects of flavonoid compounds on the activity of NADPH diaphorase prepared from the mouse brain. | 1994 | Jpn. J. Pharmacol. | pmid:7990275 |
| Nijhoff WA et al. | Enhancement of rat hepatic and gastrointestinal glutathione and glutathione S-transferases by alpha-angelicalactone and flavone. | 1995 | Carcinogenesis | pmid:7697820 |
| Shin W et al. | Structure-taste correlations in sweet dihydrochalcone, sweet dihydroisocoumarin, and bitter flavone compounds. | 1995 | J. Med. Chem. | pmid:7473560 |
| Canivenc-Lavier MC et al. | Comparative effects of flavonoids and model inducers on drug-metabolizing enzymes in rat liver. | 1996 | Toxicology | pmid:8931757 |
| Karton Y et al. | Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. | 1996 | J. Med. Chem. | pmid:8691424 |
| Siess MH et al. | Time course of induction of rat hepatic drug-metabolizing enzyme activities following dietary administration of flavonoids. | 1996 | J Toxicol Environ Health | pmid:8968409 |
| Ji XD et al. | Interactions of flavonoids and other phytochemicals with adenosine receptors. | 1996 | J. Med. Chem. | pmid:8576921 |