chrysin

chrysin is a lipid of Polyketides (PK) class. Chrysin is associated with abnormalities such as Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and Colitis. The involved functions are known as Hypoxia, enzyme activity, Oxidation, inhibitors and Cell Survival. Chrysin often locates in Protoplasm, Plasma membrane, Back, Extracellular and Mitochondria. The associated genes with chrysin are CFB gene, P4HTM gene, UGT1A9 gene, CYP1A1 gene and UGT1A1 gene. The related lipids are Promega, estradiol-3-glucuronide, Steroids and Lipopolysaccharides. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of chrysin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with chrysin?

chrysin is suspected in Colitis, Toxic nephropathy, Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with chrysin

MeSH term MeSH ID Detail
Leukemia, Myeloid D007951 52 associated lipids
Seizures D012640 87 associated lipids
Hyperalgesia D006930 42 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Weight Loss D015431 56 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with chrysin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with chrysin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with chrysin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with chrysin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with chrysin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with chrysin?

Mouse Model

Mouse Model are used in the study 'Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathway.' (Dou W et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with chrysin

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Authors Title Published Journal PubMed Link
Zhao Q et al. Two CYP82D Enzymes Function as Flavone Hydroxylases in the Biosynthesis of Root-Specific 4'-Deoxyflavones in Scutellaria baicalensis. 2018 Mol Plant pmid:28842248
Kalhotra P et al. Structure⁻Activity Relationship and Molecular Docking of Natural Product Library Reveal Chrysin as a Novel Dipeptidyl Peptidase-4 (DPP-4) Inhibitor: An Integrated In Silico and In Vitro Study. 2018 Molecules pmid:29882783
Mehnath S et al. Co-encapsulation of dual drug loaded in MLNPs: Implication on sustained drug release and effectively inducing apoptosis in oral carcinoma cells. 2018 Biomed. Pharmacother. pmid:29803180
Babangida S et al. The role of molecular modelling strategies in validating the effects of chrysin on sodium arsenite-induced chromosomal and DNA damage. 2018 Hum Exp Toxicol pmid:29308674
Bagheri R et al. Synergistic Effect of Free and Nano-encapsulated Chrysin-Curcumin on Inhibition of hTERT Gene Expression in SW480 Colorectal Cancer Cell Line. 2018 Drug Res (Stuttg) pmid:29294495
Shoieb SM et al. Chrysin attenuates testosterone-induced benign prostate hyperplasia in rats. 2018 Food Chem. Toxicol. pmid:29247772
Zeinali M et al. Protective effects of chrysin on sub-acute diazinon-induced biochemical, hematological, histopathological alterations, and genotoxicity indices in male BALB/c mice. 2018 Drug Chem Toxicol pmid:29092670
KuÅ› P et al. Extraction of bioactive phenolics from black poplar (Populus nigra L.) buds by supercritical CO and its optimization by response surface methodology. 2018 J Pharm Biomed Anal pmid:29414004
Bortolotto VC et al. Chrysin reverses the depressive-like behavior induced by hypothyroidism in female mice by regulating hippocampal serotonin and dopamine. 2018 Eur. J. Pharmacol. pmid:29355556
George MY et al. In vivo cellular and molecular gastroprotective mechanisms of chrysin; Emphasis on oxidative stress, inflammation and angiogenesis. 2018 Eur. J. Pharmacol. pmid:29126792