| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
chrysin
chrysin is a lipid of Polyketides (PK) class. Chrysin is associated with abnormalities such as Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and Colitis. The involved functions are known as Hypoxia, enzyme activity, Oxidation, inhibitors and Cell Survival. Chrysin often locates in Protoplasm, Plasma membrane, Back, Extracellular and Mitochondria. The associated genes with chrysin are CFB gene, P4HTM gene, UGT1A9 gene, CYP1A1 gene and UGT1A1 gene. The related lipids are Promega, estradiol-3-glucuronide, Steroids and Lipopolysaccharides. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of chrysin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with chrysin?
chrysin is suspected in Colitis, Toxic nephropathy, Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with chrysin
PubChem Associated disorders and diseases
What pathways are associated with chrysin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with chrysin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with chrysin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with chrysin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with chrysin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with chrysin?
Mouse Model
Mouse Model are used in the study 'Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathway.' (Dou W et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with chrysin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Shin JS et al. | Synthesis and hypoglycemic effect of chrysin derivatives. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10206552 |
| Jeong HJ et al. | Inhibition of aromatase activity by flavonoids. | 1999 | Arch. Pharm. Res. | pmid:10403137 |
| Paladini AC et al. | Flavonoids and the central nervous system: from forgotten factors to potent anxiolytic compounds. | 1999 | J. Pharm. Pharmacol. | pmid:10411210 |
| Walle UK et al. | Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2. | 1999 | Biochem. Pharmacol. | pmid:10424761 |
| Breinholt V et al. | Differential effects of dietary flavonoids on drug metabolizing and antioxidant enzymes in female rat. | 1999 | Xenobiotica | pmid:10647909 |
| Galijatovic A et al. | Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells. | 1999 | Xenobiotica | pmid:10647910 |
| Chan EC et al. | Relaxation to flavones and flavonols in rat isolated thoracic aorta: mechanism of action and structure-activity relationships. | 2000 | J. Cardiovasc. Pharmacol. | pmid:10672869 |
| Galijatovic A et al. | Induction of UDP-glucuronosyltransferase by the flavonoids chrysin and quercetin in Caco-2 cells. | 2000 | Pharm. Res. | pmid:10714603 |
| Zanoli P et al. | Behavioral characterisation of the flavonoids apigenin and chrysin. | 2000 | Fitoterapia | pmid:10930722 |
| Walle T et al. | Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in the human hepatoma cell line hep G2. | 2000 | Drug Metab. Dispos. | pmid:10950852 |
| Brown GA et al. | Effects of anabolic precursors on serum testosterone concentrations and adaptations to resistance training in young men. | 2000 | Int J Sport Nutr Exerc Metab | pmid:10997957 |
| De Santi C et al. | Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids. | 2000 | Xenobiotica | pmid:11055264 |
| Fang H et al. | Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens. | 2001 | Chem. Res. Toxicol. | pmid:11258977 |
| Heijnen CG et al. | Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups. | 2001 | Toxicol In Vitro | pmid:11259863 |
| Walle T et al. | Disposition and metabolism of the flavonoid chrysin in normal volunteers. | 2001 | Br J Clin Pharmacol | pmid:11259985 |
| Comte G et al. | C-Isoprenylation of flavonoids enhances binding affinity toward P-glycoprotein and modulation of cancer cell chemoresistance. | 2001 | J. Med. Chem. | pmid:11262086 |
| Liang YC et al. | Suppression of inducible cyclooxygenase and nitric oxide synthase through activation of peroxisome proliferator-activated receptor-gamma by flavonoids in mouse macrophages. | 2001 | FEBS Lett. | pmid:11343698 |
| Galijatovic A et al. | Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in Caco-2 cells--potential role in carcinogen bioinactivation. | 2001 | Pharm. Res. | pmid:11442279 |
| Oberdörster E et al. | Common phytochemicals are ecdysteroid agonists and antagonists: a possible evolutionary link between vertebrate and invertebrate steroid hormones. | 2001 | J. Steroid Biochem. Mol. Biol. | pmid:11457661 |