| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
chrysin
chrysin is a lipid of Polyketides (PK) class. Chrysin is associated with abnormalities such as Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and Colitis. The involved functions are known as Hypoxia, enzyme activity, Oxidation, inhibitors and Cell Survival. Chrysin often locates in Protoplasm, Plasma membrane, Back, Extracellular and Mitochondria. The associated genes with chrysin are CFB gene, P4HTM gene, UGT1A9 gene, CYP1A1 gene and UGT1A1 gene. The related lipids are Promega, estradiol-3-glucuronide, Steroids and Lipopolysaccharides. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of chrysin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with chrysin?
chrysin is suspected in Colitis, Toxic nephropathy, Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with chrysin
PubChem Associated disorders and diseases
What pathways are associated with chrysin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with chrysin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with chrysin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with chrysin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with chrysin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with chrysin?
Mouse Model
Mouse Model are used in the study 'Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathway.' (Dou W et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with chrysin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wu TC et al. | Quercetin and chrysin inhibit nickel-induced invasion and migration by downregulation of TLR4/NF-κB signaling in A549 cells. | 2018 | Chem. Biol. Interact. | pmid:30016632 |
| Šarić Mustapić D et al. | The Inhibitory Effect of Flavonoid Aglycones on the Metabolic Activity of CYP3A4 Enzyme. | 2018 | Molecules | pmid:30301254 |
| Heriniaina RM et al. | Effects of six compounds with different chemical structures on melanogenesis. | 2018 | Chin J Nat Med | pmid:30322610 |
| Sun L et al. | Potential Antinociceptive Effects of Chinese Propolis and Identification on Its Active Compounds. | 2018 | J Immunol Res | pmid:30356413 |
| Aksu EH et al. | Improvement in colistin-induced reproductive damage, apoptosis, and autophagy in testes via reducing oxidative stress by chrysin. | 2018 | J. Biochem. Mol. Toxicol. | pmid:30273961 |
| Yang M et al. | Chrysin attenuates interstitial fibrosis and improves cardiac function in a rat model of acute myocardial infarction. | 2018 | J. Mol. Histol. | pmid:30225683 |
| Park W et al. | Chrysin disrupts intracellular homeostasis through mitochondria-mediated cell death in human choriocarcinoma cells. | 2018 | Biochem. Biophys. Res. Commun. | pmid:30139515 |
| Yang Z et al. | Chrysin attenuates carrageenan-induced pleurisy and lung injury via activation of SIRT1/NRF2 pathway in rats. | 2018 | Eur. J. Pharmacol. | pmid:30118661 |
| Kang MK et al. | Chrysin Ameliorates Malfunction of Retinoid Visual Cycle through Blocking Activation of AGE-RAGE-ER Stress in Glucose-Stimulated Retinal Pigment Epithelial Cells and Diabetic Eyes. | 2018 | Nutrients | pmid:30096827 |
| Hwang SH et al. | Anti-glycation, Carbonyl Trapping and Anti-inflammatory Activities of Chrysin Derivatives. | 2018 | Molecules | pmid:30018253 |
| Sassi A et al. | Chrysin, a natural and biologically active flavonoid suppresses tumor growth of mouse B16F10 melanoma cells: In vitro and In vivo study. | 2018 | Chem. Biol. Interact. | pmid:29352974 |
| Mani R and Natesan V | Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action. | 2018 | Phytochemistry | pmid:29161583 |
| Ribeiro NCS et al. | Prepubertal chrysin exposure upregulates either AR in male ventral prostate or AR and ERα in Skene's paraurethral gland of pubertal and adult gerbils. | 2018 | Fitoterapia | pmid:29132837 |
| Das S et al. | Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses. | 2018 | J. Photochem. Photobiol. B, Biol. | pmid:29102848 |
| Lin YM et al. | Chrysin Attenuates Cell Viability of Human Colorectal Cancer Cells through Autophagy Induction Unlike 5-Fluorouracil/Oxaliplatin. | 2018 | Int J Mol Sci | pmid:29899208 |
| Menon AH et al. | Sustained release of chrysin from chitosan-based scaffolds promotes mesenchymal stem cell proliferation and osteoblast differentiation. | 2018 | Carbohydr Polym | pmid:29804987 |
| Rasouli S and Zarghami N | Synergistic Growth Inhibitory Effects of Chrysin and Metformin Combination on Breast Cancer Cells through hTERT and Cyclin D1 Suppression | 2018 | Asian Pac. J. Cancer Prev. | pmid:29693804 |
| Wang J et al. | Chrysin suppresses proliferation, migration, and invasion in glioblastoma cell lines via mediating the ERK/Nrf2 signaling pathway. | 2018 | Drug Des Devel Ther | pmid:29662304 |
| Deldar Y et al. | An in vitro examination of the antioxidant, cytoprotective and anti-inflammatory properties of chrysin-loaded nanofibrous mats for potential wound healing applications. | 2018 | Artif Cells Nanomed Biotechnol | pmid:28595461 |
| Khaligh F et al. | Effects of in ovo injection of chrysin, quercetin and ascorbic acid on hatchability, somatic attributes, hepatic oxidative status and early post-hatch performance of broiler chicks. | 2018 | J Anim Physiol Anim Nutr (Berl) | pmid:28636279 |