| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
chrysin
chrysin is a lipid of Polyketides (PK) class. Chrysin is associated with abnormalities such as Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and Colitis. The involved functions are known as Hypoxia, enzyme activity, Oxidation, inhibitors and Cell Survival. Chrysin often locates in Protoplasm, Plasma membrane, Back, Extracellular and Mitochondria. The associated genes with chrysin are CFB gene, P4HTM gene, UGT1A9 gene, CYP1A1 gene and UGT1A1 gene. The related lipids are Promega, estradiol-3-glucuronide, Steroids and Lipopolysaccharides. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of chrysin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with chrysin?
chrysin is suspected in Colitis, Toxic nephropathy, Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with chrysin
PubChem Associated disorders and diseases
What pathways are associated with chrysin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with chrysin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with chrysin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with chrysin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with chrysin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with chrysin?
Mouse Model
Mouse Model are used in the study 'Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathway.' (Dou W et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with chrysin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Goes ATR et al. | Protective role of chrysin on 6-hydroxydopamine-induced neurodegeneration a mouse model of Parkinson's disease: Involvement of neuroinflammation and neurotrophins. | 2018 | Chem. Biol. Interact. | pmid:29054324 |
| Park W et al. | Chrysin disrupts intracellular homeostasis through mitochondria-mediated cell death in human choriocarcinoma cells. | 2018 | Biochem. Biophys. Res. Commun. | pmid:30139515 |
| Yang Z et al. | Chrysin attenuates carrageenan-induced pleurisy and lung injury via activation of SIRT1/NRF2 pathway in rats. | 2018 | Eur. J. Pharmacol. | pmid:30118661 |
| Kang MK et al. | Chrysin Ameliorates Malfunction of Retinoid Visual Cycle through Blocking Activation of AGE-RAGE-ER Stress in Glucose-Stimulated Retinal Pigment Epithelial Cells and Diabetic Eyes. | 2018 | Nutrients | pmid:30096827 |
| Hwang SH et al. | Anti-glycation, Carbonyl Trapping and Anti-inflammatory Activities of Chrysin Derivatives. | 2018 | Molecules | pmid:30018253 |
| Zhao X et al. | Simultaneous Determination of Chrysin and Tectochrysin from Fruits by UPLC-MS/MS and Its Application to a Comparative Pharmacokinetic Study in Normal and Dementia Rats. | 2018 | Molecules | pmid:30002311 |
| Lee EJ et al. | Chrysin Inhibits Advanced Glycation End Products-Induced Kidney Fibrosis in Renal Mesangial Cells and Diabetic Kidneys. | 2018 | Nutrients | pmid:29987200 |
| Firouzi-Amandi A et al. | Chrysin-nanoencapsulated PLGA-PEG for macrophage repolarization: Possible application in tissue regeneration. | 2018 | Biomed. Pharmacother. | pmid:29909345 |
| Nagasaka M et al. | Anti-Tumorigenic Activity of Chrysin from via Non-Genotoxic p53 Activation through the ATM-Chk2 Pathway. | 2018 | Molecules | pmid:29890668 |
| Kalhotra P et al. | Structureâ»Activity Relationship and Molecular Docking of Natural Product Library Reveal Chrysin as a Novel Dipeptidyl Peptidase-4 (DPP-4) Inhibitor: An Integrated In Silico and In Vitro Study. | 2018 | Molecules | pmid:29882783 |
| Mehnath S et al. | Co-encapsulation of dual drug loaded in MLNPs: Implication on sustained drug release and effectively inducing apoptosis in oral carcinoma cells. | 2018 | Biomed. Pharmacother. | pmid:29803180 |
| Babangida S et al. | The role of molecular modelling strategies in validating the effects of chrysin on sodium arsenite-induced chromosomal and DNA damage. | 2018 | Hum Exp Toxicol | pmid:29308674 |
| Lin YM et al. | Chrysin Attenuates Cell Viability of Human Colorectal Cancer Cells through Autophagy Induction Unlike 5-Fluorouracil/Oxaliplatin. | 2018 | Int J Mol Sci | pmid:29899208 |
| Menon AH et al. | Sustained release of chrysin from chitosan-based scaffolds promotes mesenchymal stem cell proliferation and osteoblast differentiation. | 2018 | Carbohydr Polym | pmid:29804987 |
| Rasouli S and Zarghami N | Synergistic Growth Inhibitory Effects of Chrysin and Metformin Combination on Breast Cancer Cells through hTERT and Cyclin D1 Suppression | 2018 | Asian Pac. J. Cancer Prev. | pmid:29693804 |
| Wang J et al. | Chrysin suppresses proliferation, migration, and invasion in glioblastoma cell lines via mediating the ERK/Nrf2 signaling pathway. | 2018 | Drug Des Devel Ther | pmid:29662304 |
| KuÅ› P et al. | Extraction of bioactive phenolics from black poplar (Populus nigra L.) buds by supercritical CO and its optimization by response surface methodology. | 2018 | J Pharm Biomed Anal | pmid:29414004 |
| Bortolotto VC et al. | Chrysin reverses the depressive-like behavior induced by hypothyroidism in female mice by regulating hippocampal serotonin and dopamine. | 2018 | Eur. J. Pharmacol. | pmid:29355556 |
| Larit F et al. | Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants. | 2018 | Phytomedicine | pmid:29496172 |
| Chassagne F et al. | A metabolomic approach to identify anti-hepatocarcinogenic compounds from plants used traditionally in the treatment of liver diseases. | 2018 | Fitoterapia | pmid:29477305 |