| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
Total
3
20-HEDE
20-hede is a lipid of Fatty Acyls (FA) class. 20-hede is associated with abnormalities such as Myocardial Infarction and Hypertensive disease. The involved functions are known as Infarction, Obstruction, Anabolism, inhibitors and caspase-3 activity. 20-hede often locates in Myocardium, Blood, Microsomes, cell body and Protoplasm. The associated genes with 20-HEDE are SLC33A1 gene and AGT gene.
Cross Reference
Introduction
To understand associated biological information of 20-HEDE, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 20-HEDE?
20-HEDE is suspected in Myocardial Infarction, Hypertensive disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 20-HEDE
PubChem Associated disorders and diseases
What pathways are associated with 20-HEDE
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 20-HEDE?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 20-HEDE?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 20-HEDE?
There are no associated biomedical information in the current reference collection.
What genes are associated with 20-HEDE?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 20-HEDE?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 20-HEDE
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Garcia V et al. | Androgen-induced hypertension in angiotensinogen deficient mice: role of 20-HETE and EETS. | 2015 Jan-Mar | Prostaglandins Other Lipid Mediat. | pmid:25526688 |
| Ren Y et al. | Mechanism of impaired afferent arteriole myogenic response in Dahl salt-sensitive rats: role of 20-HETE. | 2014 | Am. J. Physiol. Renal Physiol. | pmid:24990891 |
| Ding Y et al. | 20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension. | 2013 | Am. J. Physiol. Renal Physiol. | pmid:23825080 |
| Tunctan B et al. | Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock. | 2013 | Nitric Oxide | pmid:23684565 |
| Yu W et al. | Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer. | 2012 | Toxicol. Appl. Pharmacol. | pmid:22841774 |
| Renic M et al. | Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures. | 2012 | Am. J. Physiol. Heart Circ. Physiol. | pmid:22245774 |
| Hoff U et al. | Inhibition of 20-HETE synthesis and action protects the kidney from ischemia/reperfusion injury. | 2011 | Kidney Int. | pmid:20962739 |
| Roman RJ et al. | 20-HETE in acute kidney injury. | 2011 | Kidney Int. | pmid:21157458 |
| Sodhi K et al. | CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent. | 2010 | Hypertension | pmid:20837888 |
| Medhora M et al. | 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells. | 2008 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:18296498 |