PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Zollinger-Ellison Syndrome D015043 1 associated lipids
Anal Gland Neoplasms D000694 1 associated lipids
Mastocytosis, Systemic D034721 1 associated lipids
Trigeminal Neuralgia D014277 1 associated lipids
Pulmonary Aspergillosis D055732 1 associated lipids
Persistent Fetal Circulation Syndrome D010547 1 associated lipids
Angioedemas, Hereditary D054179 2 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
Cryptorchidism D003456 2 associated lipids
Decapitation D049248 2 associated lipids
Cystitis, Interstitial D018856 2 associated lipids
Asthma, Aspirin-Induced D055963 2 associated lipids
Choroid Diseases D015862 2 associated lipids
Optic Neuropathy, Ischemic D018917 2 associated lipids
Wounds, Stab D014951 3 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Cryptococcosis D003453 3 associated lipids
Cholangitis D002761 3 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Dirofilariasis D004184 3 associated lipids
Airway Remodeling D056151 3 associated lipids
HTLV-I Infections D015490 3 associated lipids
Respiratory Sounds D012135 3 associated lipids
Ascariasis D001196 3 associated lipids
Sleep Disorders, Circadian Rhythm D020178 3 associated lipids
Idiopathic Pulmonary Fibrosis D054990 4 associated lipids
Goiter D006042 4 associated lipids
Headache D006261 4 associated lipids
Actinobacillus Infections D000189 4 associated lipids
Urticaria Pigmentosa D014582 4 associated lipids
Meningoencephalitis D008590 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Nasal Obstruction D015508 4 associated lipids
Muscular Dystrophy, Animal D009137 5 associated lipids
Vasculitis, Leukocytoclastic, Cutaneous D018366 5 associated lipids
Hematoma D006406 5 associated lipids
Myeloproliferative Disorders D009196 5 associated lipids
Sneezing D012912 6 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Tauopathies D024801 6 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Thrombophilia D019851 6 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Leukodystrophy, Globoid Cell D007965 6 associated lipids
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Folliculitis D005499 7 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Carotid Artery Thrombosis D002341 7 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Thyroid Diseases D013959 8 associated lipids
Leiomyoma D007889 8 associated lipids
Leukemia, Basophilic, Acute D015471 9 associated lipids
Chondrosarcoma D002813 9 associated lipids
Thyroiditis, Autoimmune D013967 9 associated lipids
Retinopathy of Prematurity D012178 9 associated lipids
Rhinitis D012220 10 associated lipids
Coronary Restenosis D023903 10 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Dehydration D003681 11 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Fetal Weight D020567 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Urticaria D014581 13 associated lipids
Sarcoidosis D012507 13 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Hypercalcemia D006934 13 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Encephalitis D004660 15 associated lipids
Astrocytoma D001254 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
HIV Seropositivity D006679 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Blister D001768 16 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Bronchial Spasm D001986 18 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Down Syndrome D004314 18 associated lipids
Cough D003371 19 associated lipids
Hypothermia D007035 19 associated lipids
Peptic Ulcer D010437 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Per page 10 20 50 100 | Total 189

PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with PGD2

Download all related citations
Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Lebel B et al. Spontaneous and non-specific release of histamine and PGD2 by bronchoalveolar lavage cells from asthmatic and normal subjects: effect of nedocromil sodium. 1988 Clin. Allergy pmid:2468432
Thomas RK et al. Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies. 2005 Clin. Cancer Res. pmid:16299251
Shin SW et al. 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity. 2009 Clin. Cancer Res. pmid:19690198
Koyama M et al. Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis. 2010 Clin. Cancer Res. pmid:20371690
Thévenon C et al. Gas chromatographic-mass spectrometric measurement of 15-deoxy-delta(12,14)-prostaglandin J(2), the peroxisome proliferator-activated receptor gamma ligand, in urine. 2001 Clin. Chem. pmid:11274037
Nakagawa T et al. A prostaglandin D2 metabolite is elevated in the urine of Duchenne muscular dystrophy patients and increases further from 8 years old. 2013 Clin. Chim. Acta pmid:23603101
Weiler H et al. Studies on the effects of aminopterin and methotrexate on the release of prostaglandin PGE2, PGD2, and PGI2 from small intestine in the rat in vivo. 1991 Clin. Chim. Acta pmid:1769112
Charlesworth EN et al. Cutaneous late-phase response in food-allergic children and adolescents with atopic dermatitis. 1993 Clin. Exp. Allergy pmid:7687509
Pipkorn U H1-antagonists as a tool in clarifying the pathophysiology of nasal allergy. 1990 Clin. Exp. Allergy pmid:1699643
de Graaf-in t Veld C et al. Relationship between nasal hyperreactivity, mediators and eosinophils in patients with perennial allergic rhinitis and controls. 1996 Clin. Exp. Allergy pmid:8877155
Lewis A et al. Heterogeneity in the responses of human lung mast cells to stem cell factor. 2013 Clin. Exp. Allergy pmid:23278880
Genovese A et al. Loratadine and desethoxylcarbonyl-loratadine inhibit the immunological release of mediators from human Fc epsilon RI+ cells. 1997 Clin. Exp. Allergy pmid:9179431
Wang DY et al. Prostaglandin D2 measurement in nasal secretions is not a reliable marker for mast cell activation in atopic patients. 1995 Clin. Exp. Allergy pmid:8821304
Okayama Y et al. Inhibition profiles of sodium cromoglycate and nedocromil sodium on mediator release from mast cells of human skin, lung, tonsil, adenoid and intestine. 1992 Clin. Exp. Allergy pmid:1375128
Benyon RC The human skin mast cell. 1989 Clin. Exp. Allergy pmid:2667702
Shin MH et al. The effect of azelastine on the early allergic response. 1992 Clin. Exp. Allergy pmid:1349259
Wagenmann M et al. Unilateral nasal allergen challenge leads to bilateral release of prostaglandin D2. 1996 Clin. Exp. Allergy pmid:8732233
Salari H and Chan-Yeung M Interleukin-1 potentiates antigen-mediated arachidonic acid metabolite formation in mast cells. 1989 Clin. Exp. Allergy pmid:2513105
Hewson CA et al. A differential role for ceramide kinase in antigen/FcɛRI-mediated mast cell activation and function. 2011 Clin. Exp. Allergy pmid:21255156
Blom HM et al. Intranasal capsaicin is efficacious in non-allergic, non-infectious perennial rhinitis. A placebo-controlled study. 1997 Clin. Exp. Allergy pmid:9249272
Ono E et al. Increased production of cysteinyl leukotrienes and prostaglandin D2 during human anaphylaxis. 2009 Clin. Exp. Allergy pmid:19128354
Levy JH Biomarkers in the diagnosis of anaphylaxis: making nature disclose her mysteries. 2009 Clin. Exp. Allergy pmid:19032357
Makker HK et al. Airway endothelin levels in asthma: influence of endobronchial hypertonic saline challenge. 1999 Clin. Exp. Allergy pmid:10051729
Shichijo M et al. A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep. 2009 Clin. Exp. Allergy pmid:19486034
Miadonna A et al. Nasal response to a single antigen challenge in patients with allergic rhinitis - inflammatory cell recruitment persists up to 48 hours. 1999 Clin. Exp. Allergy pmid:10383595
Yoshimura-Uchiyama C et al. Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2. 2004 Clin. Exp. Allergy pmid:15298571
Shichijo M et al. The effects of anti-asthma drugs on mediator release from cultured human mast cells. 1998 Clin. Exp. Allergy pmid:9824389
Obata T et al. Eicosapentaenoic acid inhibits prostaglandin D2 generation by inhibiting cyclo-oxygenase-2 in cultured human mast cells. 1999 Clin. Exp. Allergy pmid:10457118
Szczeklik A et al. Safety of a specific COX-2 inhibitor in aspirin-induced asthma. 2001 Clin. Exp. Allergy pmid:11251623
Nielsen PN et al. Cetirizine inhibits skin reactions but not mediator release in immediate and developing late-phase allergic cutaneous reactions. A double-blind, placebo-controlled study. 2001 Clin. Exp. Allergy pmid:11591187
Higashi N et al. A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma. 2002 Clin. Exp. Allergy pmid:12372129
Mutalithas K et al. CRTH2 expression on T cells in asthma. 2010 Clin. Exp. Immunol. pmid:20491797
Vicenzi E et al. Human mononuclear phagocytes from different anatomical sites differ in their capacity to metabolize arachidonic acid. 1984 Clin. Exp. Immunol. pmid:6432383
Eguchi M et al. Lipopolysaccharide induces proinflammatory cytokines and chemokines in experimental otitis media through the prostaglandin D2 receptor (DP)-dependent pathway. 2011 Clin. Exp. Immunol. pmid:21166666
Xue L et al. Interaction between prostaglandin D and chemoattractant receptor-homologous molecule expressed on Th2 cells mediates cytokine production by Th2 lymphocytes in response to activated mast cells. 2009 Clin. Exp. Immunol. pmid:19220324
Kim SH et al. Toluene diisocyanate (TDI) regulates haem oxygenase-1/ferritin expression: implications for toluene diisocyanate-induced asthma. 2010 Clin. Exp. Immunol. pmid:20345975
Nithipatikom K et al. Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion. 2002 Clin. Exp. Metastasis pmid:12498388
Wang XS and Lau HY Beta-adrenoceptor-mediated inhibition of mediator release from human peripheral blood-derived mast cells. 2006 Clin. Exp. Pharmacol. Physiol. pmid:16895550
Kanamori S et al. Effects of dietary fibre on dimethylhydrazine-induced changes in prostanoid concentrations in rat colonic mucosa. 1995 Clin. Exp. Pharmacol. Physiol. pmid:8575110
Nolan PN et al. Participation of prostanoids in chemical activation of the pericardial pressor reflex in dogs. 1985 Jan-Feb Clin. Exp. Pharmacol. Physiol. pmid:3924453
Fukui A et al. Effects of prostaglandin D2 and omeprazole on indomethacin-induced gastric ulcers in rats. 1988 Clin. Exp. Pharmacol. Physiol. pmid:3149561
Zhang J et al. Peroxisome proliferator-activated receptor-gamma agonists attenuate angiotensin II-induced collagen type I expression in adventitial fibroblasts. 2008 Clin. Exp. Pharmacol. Physiol. pmid:18047631
Inoue K et al. Effects of 15-deoxy-Delta12,14-prostaglandin J2 on the expression of Toll-like receptor 4 and 2 in the murine lung in the presence of lipopolysaccharide. 2005 Clin. Exp. Pharmacol. Physiol. pmid:15743408
Ray DM et al. Human multiple myeloma cells express peroxisome proliferator-activated receptor gamma and undergo apoptosis upon exposure to PPARgamma ligands. 2004 Clin. Immunol. pmid:15451478
Scher JU and Pillinger MH 15d-PGJ2: the anti-inflammatory prostaglandin? 2005 Clin. Immunol. pmid:15639643
Woolhiser MR et al. Activation of human mast cells by aggregated IgG through FcgammaRI: additive effects of C3a. 2004 Clin. Immunol. pmid:15003814
Padilla J et al. Human B lymphocytes and B lymphomas express PPAR-gamma and are killed by PPAR-gamma agonists. 2002 Clin. Immunol. pmid:11987982
Reilly CM et al. Prostaglandin J(2) inhibition of mesangial cell iNOS expression. 2001 Clin. Immunol. pmid:11237557
Downard CD et al. Topical benzoic acid induces the increased biosynthesis of prostaglandin D2 in human skin in vivo. 1995 Clin. Pharmacol. Ther. pmid:7712673
Brouwer A et al. Production of eicosanoids and cytokines by Kupffer cells from young and old rats stimulated by endotoxin. 1995 Clin. Sci. pmid:7720347
Robinson C and Holgate ST Mast cell-dependent inflammatory mediators and their putative role in bronchial asthma. 1985 Clin. Sci. pmid:2981650
Horn EH et al. Longitudinal studies of platelet cyclic AMP during healthy pregnancy and pregnancies at risk of pre-eclampsia. 1995 Clin. Sci. pmid:7545563
Oku H and Umino T Molecular characterization of peroxisome proliferator-activated receptors (PPARs) and their gene expression in the differentiating adipocytes of red sea bream Pagrus major. 2008 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:18691667
He S et al. Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella). 2012 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:22079418
Sawyer MM et al. Arachidonic acid immunoregulation in lambs persistently infected with border disease virus. 1993 Comp. Immunol. Microbiol. Infect. Dis. pmid:8281741
Wallace DI et al. A Model for Spheroid versus Monolayer Response of SK-N-SH Neuroblastoma Cells to Treatment with 15-Deoxy-PGJ2. 2016 Comput Math Methods Med pmid:28044089
Fujishima H et al. Prostaglandin D2 induces chemotaxis in eosinophils via its receptor CRTH2 and eosinophils may cause severe ocular inflammation in patients with allergic conjunctivitis. 2005 Cornea pmid:16227827
Kaye AD et al. Analysis of thromboxane receptor-mediated responses in the feline pulmonary vascular bed. 1995 Crit. Care Med. pmid:7528116
Collin M et al. Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15-deoxydelta12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin. 2004 Crit. Care Med. pmid:15090969
Trottein F et al. Role of the D prostanoid receptor 1 in the modulation of immune and inflammatory responses. 2004 Crit. Rev. Immunol. pmid:15663363
Frieri M et al. Mast cell activation syndrome: a review. 2013 Curr Allergy Asthma Rep pmid:23179866
Niyonsaba F et al. Epithelial cell-derived antibacterial peptides human beta-defensins and cathelicidin: multifunctional activities on mast cells. 2003 Curr Drug Targets Inflamm Allergy pmid:14561157
Ji Y et al. Nutrient-induced inflammation in the intestine. 2011 Curr Opin Clin Nutr Metab Care pmid:21587069
Huang ZL et al. Prostaglandins and adenosine in the regulation of sleep and wakefulness. 2007 Curr Opin Pharmacol pmid:17129762
Cuzzocrea S Peroxisome proliferator-activated receptors and acute lung injury. 2006 Curr Opin Pharmacol pmid:16580256
Huang ZL et al. The role of adenosine in the regulation of sleep. 2011 Curr Top Med Chem pmid:21401496
Ulven T and Kostenis E Targeting the prostaglandin D2 receptors DP and CRTH2 for treatment of inflammation. 2006 Curr Top Med Chem pmid:16918458
Sasaguri T and Miwa Y Prostaglandin J2 family and the cardiovascular system. 2004 Curr Vasc Pharmacol pmid:15320511
Arima M and Fukuda T Prostaglandin D2 receptors DP and CRTH2 in the pathogenesis of asthma. 2008 Curr. Mol. Med. pmid:18691063
Stenson WF The universe of arachidonic acid metabolites in inflammatory bowel disease: can we tell the good from the bad? 2014 Curr. Opin. Gastroenterol. pmid:24837228
Mitsumori S Recent progress in work on PGD2 antagonists for drugs targeting allergic diseases. 2004 Curr. Pharm. Des. pmid:15579050
Meier CA et al. Regulation of the interleukin-1 receptor antagonist in THP-1 cells by ligands of the peroxisome proliferator-activated receptor gamma. 2002 Cytokine pmid:12160520
Moulin D et al. Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells. 2007 Cytokine pmid:18023358
Dubertret L et al. Biological and cellular responses to grass pollen in sensitive patients. 1989 Dermatologica pmid:2476344
Ikai K et al. Prostaglandin D2, a mediator in both immediate and delayed-type immune reactions in the skin. 1989 Dermatologica pmid:2506083
Huddleston KW et al. Influence of prostaglandin D2 on hemodynamic effects of group B streptococcus in neonatal lambs. 1986 Dev Pharmacol Ther pmid:3530674
Wilhelm D et al. Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. 2005 Dev. Biol. pmid:16185683
Moniot B et al. Hematopoietic prostaglandin D synthase (H-Pgds) is expressed in the early embryonic gonad and participates to the initial nuclear translocation of the SOX9 protein. 2011 Dev. Dyn. pmid:21887724
Yasugi E et al. Peroxisome proliferator-activated receptor gamma ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells. 2006 Dev. Growth Differ. pmid:16573735
Adams IR and McLaren A Sexually dimorphic development of mouse primordial germ cells: switching from oogenesis to spermatogenesis. 2002 Development pmid:11874911
Moniot B et al. Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis. 2014 Development pmid:25142465
Moniot B et al. The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation. 2009 Development pmid:19429785
Souza SC et al. BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones. 1998 Diabetes pmid:9568706
Maggi LB et al. Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression. 2000 Diabetes pmid:10868955
Kämpfer H et al. Wound inflammation in diabetic ob/ob mice: functional coupling of prostaglandin biosynthesis to cyclooxygenase-1 activity in diabetes-impaired wound healing. 2005 Diabetes pmid:15855344
Xie Y et al. Differentiation-dependent regulation of the cyclooxygenase cascade during adipogenesis suggests a complex role for prostaglandins. 2006 Diabetes Obes Metab pmid:16367886
Flachs P et al. Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids. 2011 Diabetologia pmid:21779874
Casimir DA et al. Preadipocyte differentiation blocked by prostaglandin stimulation of prostanoid FP2 receptor in murine 3T3-L1 cells. 1996 Differentiation pmid:8765050
Fox CC et al. Modulation of mediator release from human intestinal mast cells by sulfasalazine and 5-aminosalicylic acid. 1991 Dig. Dis. Sci. pmid:1703070
Giardiello FM et al. Prostaglandin levels in human colorectal mucosa: effects of sulindac in patients with familial adenomatous polyposis. 1998 Dig. Dis. Sci. pmid:9512123
Bruck R et al. Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor. 2009 Dig. Dis. Sci. pmid:18594976
Zhang S et al. Prostaglandin D2 receptor D-type prostanoid receptor 2 mediates eosinophil trafficking into the esophagus. 2014 Dis. Esophagus pmid:24165271
Birbian N et al. No association of PTGDR -441C/T polymorphism with asthma in a North Indian population. 2011 Dis. Markers pmid:22182808
PPAR activators and gastroenterology. 2004 Drug News Perspect. pmid:15801147
Pettipher R and Hansel TT Antagonists of the prostaglandin D2 receptor CRTH2. 2008 Jul-Aug Drug News Perspect. pmid:18836589
Campbell A et al. Overview of allergic mechanisms. Ebastine has more than an antihistamine effect. 1996 Drugs pmid:8983912
Woodward DF et al. Studies on leukotriene D4 as an eosinophil chemoattractant. 1991 Drugs Exp Clin Res pmid:1841046
Naclerio R et al. The role of inflammatory mediators in allergic rhinitis. 1986 Ear Nose Throat J pmid:3459645
Ito S et al. Problems in production of prostaglandin D2-specific antibody. 1988 Eicosanoids pmid:3273218
Seregi A et al. Functionally diverse purinergic P2Y-receptors mediate prostanoid synthesis in cultured rat astrocytes: the role of ATP-induced phosphatidyl-inositol breakdown. 1992 Eicosanoids pmid:1333251