PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Pulmonary Aspergillosis D055732 1 associated lipids
Persistent Fetal Circulation Syndrome D010547 1 associated lipids
Zollinger-Ellison Syndrome D015043 1 associated lipids
Anal Gland Neoplasms D000694 1 associated lipids
Mastocytosis, Systemic D034721 1 associated lipids
Trigeminal Neuralgia D014277 1 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
Cryptorchidism D003456 2 associated lipids
Cystitis, Interstitial D018856 2 associated lipids
Decapitation D049248 2 associated lipids
Asthma, Aspirin-Induced D055963 2 associated lipids
Choroid Diseases D015862 2 associated lipids
Optic Neuropathy, Ischemic D018917 2 associated lipids
Angioedemas, Hereditary D054179 2 associated lipids
Respiratory Sounds D012135 3 associated lipids
HTLV-I Infections D015490 3 associated lipids
Sleep Disorders, Circadian Rhythm D020178 3 associated lipids
Ascariasis D001196 3 associated lipids
Wounds, Stab D014951 3 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Cryptococcosis D003453 3 associated lipids
Cholangitis D002761 3 associated lipids
Dirofilariasis D004184 3 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Nasal Obstruction D015508 4 associated lipids
Idiopathic Pulmonary Fibrosis D054990 4 associated lipids
Goiter D006042 4 associated lipids
Headache D006261 4 associated lipids
Actinobacillus Infections D000189 4 associated lipids
Urticaria Pigmentosa D014582 4 associated lipids
Meningoencephalitis D008590 4 associated lipids
Coronavirus Infections D018352 4 associated lipids
Myeloproliferative Disorders D009196 5 associated lipids
Muscular Dystrophy, Animal D009137 5 associated lipids
Vasculitis, Leukocytoclastic, Cutaneous D018366 5 associated lipids
Hematoma D006406 5 associated lipids
Thrombophilia D019851 6 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Leukodystrophy, Globoid Cell D007965 6 associated lipids
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Sneezing D012912 6 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Tauopathies D024801 6 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Folliculitis D005499 7 associated lipids
Carotid Artery Thrombosis D002341 7 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Thyroid Diseases D013959 8 associated lipids
Leiomyoma D007889 8 associated lipids
Thyroiditis, Autoimmune D013967 9 associated lipids
Retinopathy of Prematurity D012178 9 associated lipids
Leukemia, Basophilic, Acute D015471 9 associated lipids
Chondrosarcoma D002813 9 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Rhinitis D012220 10 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Coronary Restenosis D023903 10 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Dehydration D003681 11 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Fetal Weight D020567 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Urticaria D014581 13 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Sarcoidosis D012507 13 associated lipids
Hypercalcemia D006934 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
HIV Seropositivity D006679 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Encephalitis D004660 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Astrocytoma D001254 15 associated lipids
Blister D001768 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Down Syndrome D004314 18 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Bronchial Spasm D001986 18 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Hypothermia D007035 19 associated lipids
Peptic Ulcer D010437 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Cough D003371 19 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PGD2

Download all related citations
Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Takeda K et al. 15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells. 2001 J. Biol. Chem. pmid:11687581
Tanaka T et al. Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet. 2001 Life Sci. pmid:11693274
Niyonsaba F et al. Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells. 2001 Eur. J. Immunol. pmid:11298331
Harris SG and Phipps RP The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis. 2001 Eur. J. Immunol. pmid:11298334
Tanaka H and Nagai H [Inflammation-allergy and prostanoids. (2). The role of prostanoids in allergic inflammation]. 2001 Nippon Yakurigaku Zasshi pmid:11338375
Urquhart P et al. Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11487303
Eto K et al. Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle. 2001 Eur. J. Pharmacol. pmid:11438300
Zhang X et al. Differential regulation of chemokine gene expression by 15-deoxy-delta 12,14 prostaglandin J2. 2001 J. Immunol. pmid:11390455
Inoue T et al. Serum prostaglandin D synthase level after coronary angioplasty may predict occurrence of restenosis. 2001 Thromb. Haemost. pmid:11204569
Hirai H et al. Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. 2001 J. Exp. Med. pmid:11208866
Azuma Y et al. 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-10 and IL-12 production by macrophages. 2001 Biochem. Biophys. Res. Commun. pmid:11327705
Equils O et al. Bacterial lipopolysaccharide activates HIV long terminal repeat through Toll-like receptor 4. 2001 J. Immunol. pmid:11160291
Kitatani K et al. Ceramide accelerates dephosphorylation of extracellular signal-regulated kinase 1/2 to decrease prostaglandin D(2) production in RBL-2H3 cells. 2001 Arch. Biochem. Biophys. pmid:11697858
Levonen AL et al. Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells. 2001 Arterioscler. Thromb. Vasc. Biol. pmid:11701476
Ianaro A et al. Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. 2001 FEBS Lett. pmid:11707269
Azuma Y et al. 15-Deoxy-delta(12,14)-prostaglandin J2 is a negative regulator of macrophage functions. 2001 Int. Immunopharmacol. pmid:11710539
Robbins IM et al. Increased levels of prostaglandin D(2) suggest macrophage activation in patients with primary pulmonary hypertension. 2001 Chest pmid:11713147
Jozkowicz A et al. Prostaglandin-J2 induces synthesis of interleukin-8 by endothelial cells in a PPAR-gamma-independent manner. 2001 Prostaglandins Other Lipid Mediat. pmid:11577781
Garcia Palacios V et al. Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Delta(12,14)-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728175
Levine L Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728177
Marx N et al. Peroxisome proliferator-activated receptor-gamma activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells. 2000 J. Immunol. pmid:10843708
Pica F et al. Delta(12)-prostaglandin J(2) is a potent inhibitor of influenza A virus replication. 2000 Antimicrob. Agents Chemother. pmid:10602750
Rossi A et al. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. 2000 Nature pmid:10638762
Clark RB et al. The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. 2000 J. Immunol. pmid:10640751
Reilly CM et al. Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists. 2000 J. Immunol. pmid:10640767
Dumont I et al. Regulation of endothelial nitric oxide synthase by PGD(2) in the developing choroid. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:10644584
Nojima H et al. Arachidonic acid and prostaglandin D2 cooperatively accelerate desensitization of nicotinic acetylcholine receptor channel in mouse skeletal muscles. 2000 Brain Res. pmid:10661520
Galli A et al. Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells. 2000 Hepatology pmid:10613734
Kuwamoto K et al. Possible involvement of enhanced prostaglandin E2 production in the photosensitivity in xeroderma pigmentosum group A model mice. 2000 J. Invest. Dermatol. pmid:10651981
Padilla J et al. PPAR-gamma-mediated regulation of normal and malignant B lineage cells. 2000 Ann. N. Y. Acad. Sci. pmid:10818446
Padilla J et al. Effects of 15-deoxy-delta 12,14-PGJ2 on B lineage cells. 2000 Ann. N. Y. Acad. Sci. pmid:10818475
Hwang SW et al. Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10823958
Inoue H et al. Feedback control of cyclooxygenase-2 expression through PPARgamma. 2000 J. Biol. Chem. pmid:10827178
Marvin KW et al. The 15-deoxy-delta(12,14)-prostaglandin J(2)receptor, peroxisome proliferator activated receptor-gamma (PPARgamma) is expressed in human gestational tissues and is functionally active in JEG3 choriocarcinoma cells. 2000 Placenta pmid:10833383
Shirahase H et al. Inhibitory effects of PGD2, PGJ2 and 15-deoxy-delta12,14-PGJ2 on iNOS induction in rat mesenteric artery. 2000 Life Sci. pmid:10834301
Koppal T et al. Cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) acts as a general inhibitor of inflammatory responses in activated BV-2 microglial cells. 2000 Brain Res. pmid:10837804
Asano T et al. Peroxisome proliferator-activated receptor gamma1 (PPARgamma1) expresses in rat mesangial cells and PPARgamma agonists modulate its differentiation. 2000 Biochim. Biophys. Acta pmid:10838168
Viergutz T et al. Relationship between different stages of the corpus luteum and the expression of the peroxisome proliferator-activated receptor gamma protein in bovine large lutein cells. 2000 J. Reprod. Fertil. pmid:10793637
Fennekohl A et al. Induction by interleukin 6 of G(s)-coupled prostaglandin E(2) receptors in rat hepatocytes mediating a prostaglandin E(2)-dependent inhibition of the hepatocyte's acute phase response. 2000 Hepatology pmid:10796889
Rubin GL et al. Peroxisome proliferator-activated receptor gamma ligands inhibit estrogen biosynthesis in human breast adipose tissue: possible implications for breast cancer therapy. 2000 Cancer Res. pmid:10749129
Tsubouchi Y et al. Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis. 2000 Biochem. Biophys. Res. Commun. pmid:10753637
Kawamoto Y et al. Cyclopentenone prostaglandins as potential inducers of phase II detoxification enzymes. 15-deoxy-delta(12,14)-prostaglandin j2-induced expression of glutathione S-transferases. 2000 J. Biol. Chem. pmid:10753940
Lee KH et al. Stimulatory function of gp49A, a murine Ig-like receptor, in rat basophilic leukemia cells. 2000 J. Immunol. pmid:11046024
Kasai K et al. 15-Deoxy-Delta(12,14)-prostaglandin J(2) facilitates thyroglobulin production by cultured human thyrocytes. 2000 Am. J. Physiol., Cell Physiol. pmid:11078701
Dieter P et al. Functional coupling of cyclooxygenase 1 and 2 to discrete prostanoid synthases in liver macrophages. 2000 Biochem. Biophys. Res. Commun. pmid:11027502
Enomoto A et al. Redundant and segregated functions of granule-associated heparin-binding group II subfamily of secretory phospholipases A2 in the regulation of degranulation and prostaglandin D2 synthesis in mast cells. 2000 J. Immunol. pmid:11034411
Sugiyama H et al. Peroxisome proliferator-activated receptors are expressed in human cultured mast cells: a possible role of these receptors in negative regulation of mast cell activation. 2000 Eur. J. Immunol. pmid:11093153
Faveeuw C et al. Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-12 production in murine dendritic cells. 2000 FEBS Lett. pmid:11119715
Padilla J et al. Peroxisome proliferator activator receptor-gamma agonists and 15-deoxy-Delta(12,14)(12,14)-PGJ(2) induce apoptosis in normal and malignant B-lineage cells. 2000 J. Immunol. pmid:11120820
Sharif NA et al. Pharmacology and autoradiography of human DP prostanoid receptors using [(3)H]-BWA868C, a DP receptor-selective antagonist radioligand. 2000 Br. J. Pharmacol. pmid:11082108
Hortelano S et al. Contribution of cyclopentenone prostaglandins to the resolution of inflammation through the potentiation of apoptosis in activated macrophages. 2000 J. Immunol. pmid:11086094
Fukushima S et al. Preparation and evaluation of o/w type emulsions containing antitumor prostaglandin. 2000 Adv. Drug Deliv. Rev. pmid:11104898
Honma S et al. Effects of naturally-occurring acid fog on inflammatory mediators in airway and pulmonary functions in asthmatic patients. 2000 Respir Med pmid:11059945
Schaiff WT et al. Peroxisome proliferator-activated receptor-gamma modulates differentiation of human trophoblast in a ligand-specific manner. 2000 J. Clin. Endocrinol. Metab. pmid:11061552
Saarinen JV et al. Release of histamine and leukotriene C4 in immediate allergic wheal reaction as measured with the microdialysis technique. 2000 Arch. Dermatol. Res. pmid:10966057
Miyahara T et al. Peroxisome proliferator-activated receptors and hepatic stellate cell activation. 2000 J. Biol. Chem. pmid:10969082
Vanaja DK et al. Tumor prevention and antitumor immunity with heat shock protein 70 induced by 15-deoxy-delta12,14-prostaglandin J2 in transgenic adenocarcinoma of mouse prostate cells. 2000 Cancer Res. pmid:10987274
Soler M et al. Human vascular smooth muscle cells but not endothelial cells express prostaglandin E synthase. 2000 Circ. Res. pmid:10988243
Sakamoto H et al. Involvement of phospholipid hydroperoxide glutathione peroxidase in the modulation of prostaglandin D2 synthesis. 2000 J. Biol. Chem. pmid:11010961
Yokoyama Y et al. Synergistic antiproliferative effect of delta 12-prostaglandin J2 (delta 12-PGJ2) and hyperthermia on human esophageal cancer cell lines. 2000 Hum. Cell pmid:10937344
Davis TL and Sharif NA Pharmacological characterization of [(3)H]-prostaglandin E(2) binding to the cloned human EP(4) prostanoid receptor. 2000 Br. J. Pharmacol. pmid:10952683
Woodward DF et al. Replacement of the carboxylic acid group of prostaglandin f(2alpha) with a hydroxyl or methoxy substituent provides biologically unique compounds. 2000 Br. J. Pharmacol. pmid:10952685
Nishio T et al. Molecular identification of a rat novel organic anion transporter moat1, which transports prostaglandin D(2), leukotriene C(4), and taurocholate. 2000 Biochem. Biophys. Res. Commun. pmid:10973807
Heneka MT et al. Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. 2000 J. Neurosci. pmid:10995830
Uchida K Induction of glutathione S-transferase by prostaglandins. 2000 Mech. Ageing Dev. pmid:10996013
Miwa Y et al. 15-Deoxy-Delta(12,14)-prostaglandin J(2) induces G(1) arrest and differentiation marker expression in vascular smooth muscle cells. 2000 Mol. Pharmacol. pmid:10999955
Jozkowicz A et al. Ligands of peroxisome proliferator-activated receptor-gamma increase the generation of vascular endothelial growth factor in vascular smooth muscle cells and in macrophages. 2000 Acta Biochim. Pol. pmid:11996104
Steinbrink K et al. Induction of dendritic cell maturation and modulation of dendritic cell-induced immune responses by prostaglandins. 2000 Arch. Dermatol. Res. pmid:11000287
Sugimoto Y et al. Influences of everninomicin, vancomycin and teicoplanin on chemical mediator release from rat peritoneal mast cells. 2000 Jpn. J. Pharmacol. pmid:11001175
Kawahito Y et al. 15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats. 2000 J. Clin. Invest. pmid:10903334
Kershenovich A et al. Angiotensin II does not mediate the pressor response to PGD2 (icv). 2000 J Renin Angiotensin Aldosterone Syst pmid:11967813
Gaspar Elsas MI et al. Murine myeloid progenitor responses to GM-CSF and eosinophil precursor responses to IL-5 represent distinct targets for downmodulation by prostaglandin E(2). 2000 Br. J. Pharmacol. pmid:10903977
Karimi K et al. Stem cell factor and interleukin-4 increase responsiveness of mast cells to substance P. 2000 Exp. Hematol. pmid:10880748
Chattopadhyay N et al. Expression of peroxisome proliferator-activated receptors (PPARS) in human astrocytic cells: PPARgamma agonists as inducers of apoptosis. 2000 J. Neurosci. Res. pmid:10861801
Paik JH et al. Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways. 2000 J. Biol. Chem. pmid:10866999
Maggi LB et al. Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression. 2000 Diabetes pmid:10868955
Abdelaziz MM et al. The potential of active metabolites of antihistamines in the management of allergic disease. 2000 Allergy pmid:10843422
Norwitz ER and Wilson T Secretory component: a potential regulator of endometrial-decidual prostaglandin production in early human pregnancy. 2000 Am. J. Obstet. Gynecol. pmid:10920317
Yoshida Y et al. Prostaglandin E (EP) receptor subtypes and sleep: promotion by EP4 and inhibition by EP1/EP2. 2000 Neuroreport pmid:10923657
Marra F et al. Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells. 2000 Gastroenterology pmid:10930382
Ikeda Y et al. Suppression of rat thromboxane synthase gene transcription by peroxisome proliferator-activated receptor gamma in macrophages via an interaction with NRF2. 2000 J. Biol. Chem. pmid:10930400
Bamba H et al. Prostaglandins up-regulate vascular endothelial growth factor production through distinct pathways in differentiated U937 cells. 2000 Biochem. Biophys. Res. Commun. pmid:10873632
Ikeda U et al. Peroxisome proliferator-activated receptor-gamma ligands inhibit nitric oxide synthesis in vascular smooth muscle cells. 2000 Hypertension pmid:10856269
Ajuebor MN et al. Cyclooxygenase-2-derived prostaglandin D(2) is an early anti-inflammatory signal in experimental colitis. 2000 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:10898767
Sugiyama H et al. Peroxisome proliferator-activated receptors are expressed in mouse bone marrow-derived mast cells. 2000 FEBS Lett. pmid:10675550
Matsuoka T et al. Prostaglandin D2 as a mediator of allergic asthma. 2000 Science pmid:10720327
Urade Y and Hayaishi O Prostaglandin D synthase: structure and function. 2000 Vitam. Horm. pmid:10668396
Castrillo A et al. Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-Delta(12,14)-prostaglandin J(2) in activated murine macrophages. 2000 Mol. Cell. Biol. pmid:10669746
Butler R et al. Nonapoptotic cell death associated with S-phase arrest of prostate cancer cells via the peroxisome proliferator-activated receptor gamma ligand, 15-deoxy-delta12,14-prostaglandin J2. 2000 Cell Growth Differ. pmid:10672903
Liu JH Circadian variations of prostaglandins in the rabbit aqueous humor. 2000 J Ocul Pharmacol Ther pmid:10673131
Kowalski ML et al. Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients. 2000 Am. J. Respir. Crit. Care Med. pmid:10673176
Yamashita M et al. Inhibition by troglitazone of the antigen-induced production of leukotrienes in immunoglobulin E-sensitized RBL-2H3 cells. 2000 Br. J. Pharmacol. pmid:10694244
Kubata BK et al. Identification of a novel prostaglandin f(2alpha) synthase in Trypanosoma brucei. 2000 J. Exp. Med. pmid:11067881
Takeda K et al. Peroxisome proliferator-activated receptor gamma activators downregulate angiotensin II type 1 receptor in vascular smooth muscle cells. 2000 Circulation pmid:11023940
Łazarewicz JW et al. NMDA receptors and nitric oxide regulate prostaglandin D2 synthesis in the rabbit hippocampus in vivo. 2000 Acta Neurobiol Exp (Wars) pmid:11200170
Zuckerman SH et al. The effect of gamma-interferon to inhibit macrophage-high density lipoprotein interactions is reversed by 15-deoxy-delta12,14-prostaglandin J2. 2000 Lipids pmid:11132183
Wright DH et al. The human prostanoid DP receptor stimulates mucin secretion in LS174T cells. 2000 Br. J. Pharmacol. pmid:11139429
Li LH and Ku BS [Regulation of SWS by hormones and cytokines]. 2000 Sheng Li Ke Xue Jin Zhan pmid:12532764
Kitatani K et al. Role of phospholipase D-derived phosphatidic acid as a substrate for phospholipase A2 in RBL-2H3 cells. 2000 Biol. Pharm. Bull. pmid:11145171
Hamel L et al. Induction of heat shock protein 70 by herbimycin A and cyclopentenone prostaglandins in smooth muscle cells. 2000 Cell Stress Chaperones pmid:11147963