PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Airway Remodeling D056151 3 associated lipids
Asthma, Aspirin-Induced D055963 2 associated lipids
Pulmonary Aspergillosis D055732 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Idiopathic Pulmonary Fibrosis D054990 4 associated lipids
Angioedemas, Hereditary D054179 2 associated lipids
Atherosclerosis D050197 85 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Decapitation D049248 2 associated lipids
Mastocytosis, Systemic D034721 1 associated lipids
Tauopathies D024801 6 associated lipids
Coronary Restenosis D023903 10 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Fetal Weight D020567 12 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Stroke D020521 32 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Sleep Disorders, Circadian Rhythm D020178 3 associated lipids
Thrombophilia D019851 6 associated lipids
Endotoxemia D019446 27 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Optic Neuropathy, Ischemic D018917 2 associated lipids
Cystitis, Interstitial D018856 2 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Vasculitis, Leukocytoclastic, Cutaneous D018366 5 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Coronavirus Infections D018352 4 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Helicobacter Infections D016481 21 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Choroid Diseases D015862 2 associated lipids
Nasal Obstruction D015508 4 associated lipids
HTLV-I Infections D015490 3 associated lipids
Leukemia, Basophilic, Acute D015471 9 associated lipids
Leukemia, T-Cell D015458 23 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Weight Loss D015431 56 associated lipids
Reperfusion Injury D015427 65 associated lipids
Zollinger-Ellison Syndrome D015043 1 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Wounds, Stab D014951 3 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Urticaria Pigmentosa D014582 4 associated lipids
Urticaria D014581 13 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Uremia D014511 33 associated lipids
Trigeminal Neuralgia D014277 1 associated lipids
Translocation, Genetic D014178 20 associated lipids
Thyroiditis, Autoimmune D013967 9 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Thyroid Diseases D013959 8 associated lipids
Thrombosis D013927 49 associated lipids
Thrombocytopenia D013921 15 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Stomach Ulcer D013276 75 associated lipids
Sneezing D012912 6 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
Seizures D012640 87 associated lipids
Osteosarcoma D012516 50 associated lipids
Sarcoma 180 D012510 21 associated lipids
Sarcoidosis D012507 13 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Rhinitis D012220 10 associated lipids
Retinopathy of Prematurity D012178 9 associated lipids
Respiratory Sounds D012135 3 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Precancerous Conditions D011230 48 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Polycystic Ovary Syndrome D011085 14 associated lipids
Pleurisy D010998 20 associated lipids
Persistent Fetal Circulation Syndrome D010547 1 associated lipids
Peritonitis D010538 38 associated lipids
Peptic Ulcer D010437 19 associated lipids
Parkinson Disease D010300 53 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Pain D010146 64 associated lipids
Neuroblastoma D009447 66 associated lipids
Nerve Degeneration D009410 53 associated lipids
Nasal Polyps D009298 26 associated lipids
Myocardial Infarction D009203 21 associated lipids
Myeloproliferative Disorders D009196 5 associated lipids
Muscular Dystrophy, Animal D009137 5 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Meningoencephalitis D008590 4 associated lipids
Melanoma D008545 69 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lung Diseases D008171 37 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PGD2

Download all related citations
Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Hayden RE et al. Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2. 2009 Leukemia pmid:18923439
Csanky E et al. Lipid metabolite levels of prostaglandin D2 and eicosapentaenoic acid recovered from bronchoalveolar lavage fluid correlate with lung function of chronic obstructive pulmonary disease patients and controls. 2009 Electrophoresis pmid:19294692
Kase K et al. Inhibitory action of roxithromycin on histamine release and prostaglandin D2 production from beta-defensin 2-stimulated mast cells. 2009 Int. J. Mol. Med. pmid:19212651
Ricart KC et al. The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. 2009 Biochem. J. pmid:19161347
Yamamoto M et al. Expression and characterization of PGD2 receptors in chronic rhinosinusitis: modulation of DP and CRTH2 by PGD2. 2009 Int. Arch. Allergy Immunol. pmid:18802357
Pirianov G et al. The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse. 2009 Endocrinology pmid:18845626
Tsuji T et al. Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen. 2009 Neurochem. Res. pmid:18946735
Waku T et al. Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids. 2009 J. Mol. Biol. pmid:18977231
Bruck R et al. Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor. 2009 Dig. Dis. Sci. pmid:18594976
O'Brien JJ et al. 15-deoxy-Delta12,14 prostaglandin J2-induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis. 2009 J. Thromb. Haemost. pmid:18983509
Kalantari P et al. 15-Deoxy-Delta12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification. 2009 FASEB J. pmid:19299483
Mohri I et al. Inhibition of prostaglandin D synthase suppresses muscular necrosis. 2009 Am. J. Pathol. pmid:19359520
Moriai M et al. Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells. 2009 Int. J. Oncol. pmid:19360348
Boehme SA et al. Murine bone marrow-derived mast cells express chemoattractant receptor-homologous molecule expressed on T-helper class 2 cells (CRTh2). 2009 Int. Immunol. pmid:19346259
Ma XM et al. Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma. 2009 World J. Gastroenterol. pmid:19701967
Levy JH Biomarkers in the diagnosis of anaphylaxis: making nature disclose her mysteries. 2009 Clin. Exp. Allergy pmid:19032357
Boehme SA et al. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation. 2009 Int. Immunol. pmid:19066314
Boehme SA et al. Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms. 2009 Int. Immunol. pmid:19066315
Ding Q et al. Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. 2009 Endocrinology pmid:19074584
Schröder R et al. The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation. 2009 J. Biol. Chem. pmid:19010788
Eichele K et al. R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. 2009 Pharm. Res. pmid:19015962
Gressner OA et al. Elevated concentrations of 15-deoxy-Delta12,14-prostaglandin J2 in chronic liver disease propose therapeutic trials with peroxisome proliferator activated receptor gamma-inducing drugs. 2009 Liver Int. pmid:19018984
Kobayashi M et al. The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. 2009 Mol. Cell. Biol. pmid:19001094
Irikura D et al. Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase. 2009 J. Biol. Chem. pmid:19131342
Johansson S et al. CC16 inhibits the migration of eosinophils towards the formyl peptide fMLF but not towards PGD2. 2009 Inflammation pmid:19132521
Kim DH et al. 15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS. 2009 Carcinogenesis pmid:19136476
Di Francesco L et al. Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells. 2009 Circ. Res. pmid:19122175
Wang WM et al. PPAR-gamma agonists inhibit TGF-beta1-induced chemokine expression in human tubular epithelial cells. 2009 Acta Pharmacol. Sin. pmid:19098936
Ulbrich SE et al. Quantitative characterization of prostaglandins in the uterus of early pregnant cattle. 2009 Reproduction pmid:19470711
Shichijo M et al. A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep. 2009 Clin. Exp. Allergy pmid:19486034
Wang X et al. Potential effects of peroxisome proliferator-activated receptor activator on LPS-induced lung injury in rats. 2009 Pulm Pharmacol Ther pmid:19489131
Tokudome S et al. Glucocorticoid protects rodent hearts from ischemia/reperfusion injury by activating lipocalin-type prostaglandin D synthase-derived PGD2 biosynthesis. 2009 J. Clin. Invest. pmid:19451694
Mickleborough TD et al. Eicosapentaenoic acid is more effective than docosahexaenoic acid in inhibiting proinflammatory mediator production and transcription from LPS-induced human asthmatic alveolar macrophage cells. 2009 Clin Nutr pmid:19054597
Arnaud LT et al. Proteasome-caspase-cathepsin sequence leading to tau pathology induced by prostaglandin J2 in neuronal cells. 2009 J. Neurochem. pmid:19457109
Olmos G et al. 15-Deoxy-Delta(12,14)-prostaglandin-J(2) reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1alpha degradation. 2009 Cell. Mol. Life Sci. pmid:19458911
Brechbuhl HM et al. Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport. 2009 Free Radic. Biol. Med. pmid:19520157
Ramji DP Growth hormone-releasing peptides, CD36, and stimulation of cholesterol efflux: cyclooxygenase-2 is the link. 2009 Cardiovasc. Res. pmid:19520704
Xue L et al. Novel function of CRTH2 in preventing apoptosis of human Th2 cells through activation of the phosphatidylinositol 3-kinase pathway. 2009 J. Immunol. pmid:19494281
Yamamura K et al. Intracellular protein phosphorylation in eosinophils and the functional relevance in cytokine production. 2009 Int. Arch. Allergy Immunol. pmid:19494504
Chiba T et al. 15-Deoxy-Delta(12,14)-prostaglandin J2 induces IL-8 and GM-CSF in a human airway epithelial cell line (NCI-H292). 2009 Int. Arch. Allergy Immunol. pmid:19494510
Niki E Lipid peroxidation: physiological levels and dual biological effects. 2009 Free Radic. Biol. Med. pmid:19500666
Suk FM et al. 15-deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells. 2009 Toxicol. Lett. pmid:19429239
Kansanen E et al. Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2. 2009 Free Radic. Biol. Med. pmid:19573595
Cocca C et al. 15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest. 2009 Biochem. Pharmacol. pmid:19576185
Thura M et al. GIF-0173 protects against cerebral infarction through DP1 receptor activation. 2009 Exp. Neurol. pmid:19576888
Bernardo A et al. Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells. 2009 J. Neuropathol. Exp. Neurol. pmid:19535992
Strakhova MI et al. In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties. 2009 Br. J. Pharmacol. pmid:19413570
Bujold K et al. CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages. 2009 Cardiovasc. Res. pmid:19377069
Mrabet-Dahbi S et al. Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands. 2009 Exp. Dermatol. pmid:19382314
Li H and Pauza CD Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells. 2009 PLoS ONE pmid:19888466
Landrier JF et al. Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism. 2009 Endocrinology pmid:19833717
Lauring B et al. Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. 2009 J Clin Pharmacol pmid:19833861
Hironaka A et al. 15-Deoxy-Delta(12,14)-prostaglandin J(2) impairs the functions of histone acetyltransferases through their insolubilization in cells. 2009 Biochem. Biophys. Res. Commun. pmid:19799872
Davies NJ et al. AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects. 2009 Cancer Res. pmid:19487289
Pustovrh MC et al. MMP/ TIMP balance is modulated in vitro by 15dPGJ(2) in fetuses and placentas from diabetic rats. 2009 Eur. J. Clin. Invest. pmid:19811527
Piprek RP Genetic mechanisms underlying male sex determination in mammals. 2009 J. Appl. Genet. pmid:19875885
Csányi G et al. Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. 2008 May-Jun Pharmacol Rep pmid:18622059
Kalogeromitros D et al. A quercetin containing supplement reduces niacin-induced flush in humans. 2008 Jul-Sep Int J Immunopathol Pharmacol pmid:18831918
Papageorgiou E et al. Rosiglitazone attenuates insulin-like growth factor 1 receptor survival signaling in PC-3 cells. 2008 Jul-Aug Mol. Med. pmid:18475308
Pettipher R and Hansel TT Antagonists of the prostaglandin D2 receptor CRTH2. 2008 Jul-Aug Drug News Perspect. pmid:18836589
Takahashi N et al. Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators. 2008 Jul-Aug Channels (Austin) pmid:18769139
Tokuda H et al. Function of Rho-kinase in prostaglandin D2-induced interleukin-6 synthesis in osteoblasts. 2008 Jul-Aug Prostaglandins Leukot. Essent. Fatty Acids pmid:18771907
Wang S et al. AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells. 2008 Mol. Cell. Endocrinol. pmid:18508192
Curfs DM et al. Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology. 2008 J. Biol. Chem. pmid:18511424
Qiao L et al. Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor effects of troglitazone and 15-PGJ2. 2008 Cancer Lett. pmid:18477501
Reddy RC et al. Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}. 2008 Blood pmid:18535203
Tajima T et al. Lipopolysaccharide induces macrophage migration via prostaglandin D(2) and prostaglandin E(2). 2008 J. Pharmacol. Exp. Ther. pmid:18492946
Ghosh AK et al. Constitutive Smad signaling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferator-activated receptor-gamma. 2008 Biochem. Biophys. Res. Commun. pmid:18627765
Genovese T et al. Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury. 2008 Shock pmid:18628687
Alba G et al. Heme oxygenase-1 expression is down-regulated by angiotensin II and under hypertension in human neutrophils. 2008 J. Leukoc. Biol. pmid:18515325
Yoon HJ et al. Regulation of TLR2 expression by prostaglandins in brain glia. 2008 J. Immunol. pmid:18523308
Bissonnette SL et al. An endogenous prostaglandin enhances environmental phthalate-induced apoptosis in bone marrow B cells: activation of distinct but overlapping pathways. 2008 J. Immunol. pmid:18641309
Qiao L et al. Down-regulation of X-linked inhibitor of apoptosis synergistically enhanced peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition in colon cancer. 2008 Mol. Cancer Ther. pmid:18645029
Ragolia L et al. Lipocalin-type prostaglandin D(2) synthase stimulates glucose transport via enhanced GLUT4 translocation. 2008 Prostaglandins Other Lipid Mediat. pmid:18619553
Moreira V et al. Secretory phospholipases A(2) isolated from Bothrops asper and from Crotalus durissus terrificus snake venoms induce distinct mechanisms for biosynthesis of prostaglandins E2 and D2 and expression of cyclooxygenases. 2008 Toxicon pmid:18619987
Capobianco E et al. Effects of natural ligands of PPARgamma on lipid metabolism in placental tissues from healthy and diabetic rats. 2008 Mol. Hum. Reprod. pmid:18621767
Yang JH et al. Anti-allergic activity of an ethanol extract from Salviae miltiorrhiza. 2008 Arch. Pharm. Res. pmid:19099230
Dubourdeau M et al. Opposite roles of STAT and PPARgamma in the induction of p21WAF1 expression by IL-13 in human peripheral blood monocytes. 2008 Eur. Cytokine Netw. pmid:19103521
Horváth B et al. Carbon monoxide-prostaglandin E2 interaction in the hypothalamic circulation. 2008 Neuroreport pmid:18815586
Fujimori K et al. Enhancement of prostaglandin D(2) production through cyclooxygenase-2 and lipocalin-type prostaglandin D synthase by upstream stimulatory factor 1 in human brain-derived TE671 cells under serum starvation. 2008 Gene pmid:18817855
García-Bueno B et al. Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats. 2008 Endocrinology pmid:18079203
Muñoz U et al. On the mechanism of inhibition of p27 degradation by 15-deoxy-Delta12,14-prostaglandin J2 in lymphoblasts of Alzheimer's disease patients. 2008 Cell. Mol. Life Sci. pmid:18818877
Hounoki H et al. Activation of peroxisome proliferator-activated receptor gamma inhibits TNF-alpha-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocyte chemoattractant protein-1 expression. 2008 Bone pmid:18242157
Zhao H et al. Rubimetide (Met-Arg-Trp) derived from Rubisco exhibits anxiolytic-like activity via the DP1 receptor in male ddY mice. 2008 Peptides pmid:18243414
Ohinata K et al. Central prostaglandin D(2) stimulates food intake via the neuropeptide Y system in mice. 2008 FEBS Lett. pmid:18258196
Perbandt M et al. Structure of the extracellular glutathione S-transferase OvGST1 from the human pathogenic parasite Onchocerca volvulus. 2008 J. Mol. Biol. pmid:18258257
Kim EH et al. 15-Deoxy-Delta12,14-prostaglandin J2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: a potential role of ROS. 2008 Carcinogenesis pmid:18192694
Prenn C et al. CRTH2 is not involved in the anti-enteropooling effect of PGD2 in the small intestine. 2008 Pharmacology pmid:18212515
Rajakariar R et al. Novel biphasic role for lymphocytes revealed during resolving inflammation. 2008 Blood pmid:18218853
Kuesap J et al. Prostaglandin D2 induces heme oxygenase-1 in human retinal pigment epithelial cells. 2008 Biochem. Biophys. Res. Commun. pmid:18174022
Crabb SJ et al. BAG-1 inhibits PPARgamma-induced cell death, but not PPARgamma-induced transcription, cell cycle arrest or differentiation in breast cancer cells. 2008 Oncol. Rep. pmid:18288403
Hong HY et al. Up-regulation of heme oxygenase-1 expression through the Rac1/NADPH oxidase/ROS/p38 signaling cascade mediates the anti-inflammatory effect of 15-deoxy-delta 12,14-prostaglandin J2 in murine macrophages. 2008 FEBS Lett. pmid:18291107
Giannini L et al. Activation of cannabinoid receptors prevents antigen-induced asthma-like reaction in guinea pigs. 2008 J. Cell. Mol. Med. pmid:18266975
Malki S et al. [Prostaglandin D2: new roles in the embryonic and pathological gonad]. 2008 Med Sci (Paris) pmid:18272080
Ono E et al. Salicylamide-induced anaphylaxis: increased urinary leukotriene E4 and prostaglandin D2 metabolite. 2008 Allergy pmid:18315738
Hao GH et al. Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts. 2008 Br. J. Pharmacol. pmid:18278065
Khan AH et al. Effect of femto to nano molar concentrations of prostaglandin analogues on pregnant rat uterine contractility. 2008 Eur. J. Pharmacol. pmid:18177857
Inoue T et al. Lipocalin-type prostaglandin D synthase is a powerful biomarker for severity of stable coronary artery disease. 2008 Atherosclerosis pmid:18436228
Nomiya R et al. CRTH2 plays an essential role in the pathophysiology of Cry j 1-induced pollinosis in mice. 2008 J. Immunol. pmid:18390753
Liu Y et al. Increased expression of the peroxisome proliferator-activated receptor gamma in the immune system of weaned pigs after Escherichia coli lipopolysaccharide injection. 2008 Vet. Immunol. Immunopathol. pmid:18394717