PGD2
Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.
Cross Reference
Introduction
To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PGD2?
PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PGD2
PubChem Associated disorders and diseases
What pathways are associated with PGD2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PGD2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with PGD2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PGD2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PGD2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with PGD2?
Knock-out
Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).
Rodent Model
Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with PGD2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sanchez Mejia RO et al. | Matrix-associated transforming growth factor-beta1 primes mouse bone marrow-derived mast cells for increased high-affinity Fc receptor for immunoglobulin E-dependent eicosanoid biosynthesis. | 2000 | Am. J. Respir. Cell Mol. Biol. | pmid:10783127 |
| Feng J et al. | Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gamma. | 2000 | J. Lipid Res. | pmid:10787429 |
| Macfarlane AJ et al. | Sputum cysteinyl leukotrienes increase 24 hours after allergen inhalation in atopic asthmatics. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:10806153 |
| Taba Y et al. | Fluid shear stress induces lipocalin-type prostaglandin D(2) synthase expression in vascular endothelial cells. | 2000 | Circ. Res. | pmid:10807869 |
| Sharif NA et al. | Affinities, selectivities, potencies, and intrinsic activities of natural and synthetic prostanoids using endogenous receptors: focus on DP class prostanoids. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10772998 |
| Marvin KW et al. | The 15-deoxy-delta(12,14)-prostaglandin J(2)receptor, peroxisome proliferator activated receptor-gamma (PPARgamma) is expressed in human gestational tissues and is functionally active in JEG3 choriocarcinoma cells. | 2000 | Placenta | pmid:10833383 |
| Shirahase H et al. | Inhibitory effects of PGD2, PGJ2 and 15-deoxy-delta12,14-PGJ2 on iNOS induction in rat mesenteric artery. | 2000 | Life Sci. | pmid:10834301 |
| Bernardo A et al. | Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions. | 2000 | Eur. J. Neurosci. | pmid:10947800 |
| Kozak KR et al. | Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2. | 2000 | J. Biol. Chem. | pmid:10931854 |
| Hartert TV et al. | Prostaglandin E(2) decreases allergen-stimulated release of prostaglandin D(2) in airways of subjects with asthma. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:10934099 |
| Maxey KM et al. | The nature and composition of 15-deoxy-Delta(12,14)PGJ(2). | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10936412 |
| Clay CE et al. | 15-deoxy-Delta(12,14)PGJ(2) induces diverse biological responses via PPARgamma activation in cancer cells. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10936413 |
| Mc Clay EF | The effects of Delta(12)-PGJ(2) on malignant cells. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10936416 |
| Yokoyama Y et al. | Synergistic antiproliferative effect of delta 12-prostaglandin J2 (delta 12-PGJ2) and hyperthermia on human esophageal cancer cell lines. | 2000 | Hum. Cell | pmid:10937344 |
| Davis TL and Sharif NA | Pharmacological characterization of [(3)H]-prostaglandin E(2) binding to the cloned human EP(4) prostanoid receptor. | 2000 | Br. J. Pharmacol. | pmid:10952683 |
| Tanaka K et al. | Cutting edge: differential production of prostaglandin D2 by human helper T cell subsets. | 2000 | J. Immunol. | pmid:10679060 |
| Chan CL et al. | Characterization of prostanoid receptors mediating inhibition of histamine release from anti-IgE-activated rat peritoneal mast cells. | 2000 | Br. J. Pharmacol. | pmid:10711359 |
| Urade Y and Hayaishi O | Prostaglandin D synthase: structure and function. | 2000 | Vitam. Horm. | pmid:10668396 |
| Li L et al. | 15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors. | 2001 | J. Biol. Chem. | pmid:11477100 |
| Ahluwalia P et al. | Nedocromil sodium and levocabastine reduce the symptoms of conjunctival allergen challenge by different mechanisms. | 2001 | J. Allergy Clin. Immunol. | pmid:11544467 |
| Nicolaidis S et al. | [Variations of hypothalamic and cortical prostaglandins and monoamines reveal transitions in arousal states: microdialysis study in the rat]. | 2001 | Rev. Neurol. (Paris) | pmid:11924034 |
| Keelan J et al. | 15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11785780 |
| Pignatelli M et al. | The peroxisome proliferator-activated receptor gamma is an inhibitor of ErbBs activity in human breast cancer cells. | 2001 | J. Cell. Sci. | pmid:11739643 |
| Gervais FG et al. | Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP. | 2001 | J. Allergy Clin. Immunol. | pmid:11742277 |
| Reilly TP et al. | A protective role for cyclooxygenase-2 in drug-induced liver injury in mice. | 2001 | Chem. Res. Toxicol. | pmid:11743745 |
| Takeda K et al. | 15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells. | 2001 | J. Biol. Chem. | pmid:11687581 |
| Tanaka T et al. | Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet. | 2001 | Life Sci. | pmid:11693274 |
| Niyonsaba F et al. | Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells. | 2001 | Eur. J. Immunol. | pmid:11298331 |
| Harris SG and Phipps RP | The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis. | 2001 | Eur. J. Immunol. | pmid:11298334 |
| Tanaka H and Nagai H | [Inflammation-allergy and prostanoids. (2). The role of prostanoids in allergic inflammation]. | 2001 | Nippon Yakurigaku Zasshi | pmid:11338375 |
| Tomlinson JW et al. | Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines. | 2001 | Endocrinology | pmid:11316764 |
| Thévenon C et al. | Gas chromatographic-mass spectrometric measurement of 15-deoxy-delta(12,14)-prostaglandin J(2), the peroxisome proliferator-activated receptor gamma ligand, in urine. | 2001 | Clin. Chem. | pmid:11274037 |
| Rohn TT et al. | 15-deoxy-delta12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-gamma, induces neuronal apoptosis. | 2001 | Neuroreport | pmid:11277593 |
| Satoh T et al. | Neurotrophic actions of novel compounds designed from cyclopentenone prostaglandins. | 2001 | J. Neurochem. | pmid:11279261 |
| Drew PD and Chavis JA | The cyclopentone prostaglandin 15-deoxy-Delta(12,14) prostaglandin J2 represses nitric oxide, TNF-alpha, and IL-12 production by microglial cells. | 2001 | J. Neuroimmunol. | pmid:11282151 |
| Guyton K et al. | Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation. | 2001 | J. Leukoc. Biol. | pmid:11310850 |
| Govoni S et al. | The Cycloxygenase-2 inhibitor SC58236 is neuroprotective in an in vivo model of focal ischemia in the rat. | 2001 | Neurosci. Lett. | pmid:11311500 |
| Tsubouchi Y et al. | Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11350047 |
| Wang C et al. | Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1. | 2001 | Mol. Cell. Biol. | pmid:11287611 |
| Jiang JG et al. | Peroxisome proliferator-activated receptor gamma-mediated transcriptional up-regulation of the hepatocyte growth factor gene promoter via a novel composite cis-acting element. | 2001 | J. Biol. Chem. | pmid:11292834 |
| Serghides L and Kain KC | Peroxisome proliferator-activated receptor gamma-retinoid X receptor agonists increase CD36-dependent phagocytosis of Plasmodium falciparum-parasitized erythrocytes and decrease malaria-induced TNF-alpha secretion by monocytes/macrophages. | 2001 | J. Immunol. | pmid:11359831 |
| Urquhart P et al. | Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487303 |
| Angeli V et al. | Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection. | 2001 | J. Exp. Med. | pmid:11369785 |
| Krawiec ME et al. | Persistent wheezing in very young children is associated with lower respiratory inflammation. | 2001 | Am. J. Respir. Crit. Care Med. | pmid:11371398 |
| Saarinen JV et al. | Modulation of the immediate allergic wheal reaction in the skin by drugs inhibiting the effects of leukotriene C4 and prostaglandin D2. | 2001 | Eur. J. Clin. Pharmacol. | pmid:11372583 |
| Buechler C et al. | Adipophilin is a sensitive marker for lipid loading in human blood monocytes. | 2001 | Biochim. Biophys. Acta | pmid:11420178 |
| VanderEnde DS and Morrow JD | Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans after the application of cinnamic aldehyde. | 2001 | J. Am. Acad. Dermatol. | pmid:11423836 |
| Park JM | Role of prostaglandins in bladder smooth muscle cell gene expression. | 2001 | Urology | pmid:11378068 |
| Chang TS et al. | NQ-Y15 inhibits the calcium mobilization by elevation of cyclic AMP in rat platelets. | 2001 | Biol. Pharm. Bull. | pmid:11379764 |
| Fajas L et al. | PPAR gamma: an essential role in metabolic control. | 2001 | Nutr Metab Cardiovasc Dis | pmid:11383325 |
| Boutaud O et al. | Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid. | 2001 | Biochemistry | pmid:11389610 |
| Chen NG and Han X | Dual function of troglitazone in ICAM-1 gene expression in human vascular endothelium. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11401521 |
| Lau HY and Chan CL | Modulation of intracellular cyclic AMP in immunologically activated rat peritoneal mast cells by prostaglandin D2. | 2001 | Inflamm. Res. | pmid:11411605 |
| Serhan CN and Devchand PR | Novel antiinflammatory targets for asthma. A role for PPARgamma? | 2001 | Am. J. Respir. Cell Mol. Biol. | pmid:11415929 |
| Wang AC et al. | Peroxisome proliferator-activated receptor-gamma regulates airway epithelial cell activation. | 2001 | Am. J. Respir. Cell Mol. Biol. | pmid:11415933 |
| Eto K et al. | Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle. | 2001 | Eur. J. Pharmacol. | pmid:11438300 |
| Zhang X et al. | Differential regulation of chemokine gene expression by 15-deoxy-delta 12,14 prostaglandin J2. | 2001 | J. Immunol. | pmid:11390455 |
| Inoue T et al. | Serum prostaglandin D synthase level after coronary angioplasty may predict occurrence of restenosis. | 2001 | Thromb. Haemost. | pmid:11204569 |
| Hirai H et al. | Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. | 2001 | J. Exp. Med. | pmid:11208866 |
| Guan Y et al. | Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature. | 2001 | Am. J. Physiol. Renal Physiol. | pmid:11704554 |
| Bochenek G et al. | [Prostaglandin D2: biosynthesis, biological properties and participation in bronchial asthma]. | 2001 | Pol. Arch. Med. Wewn. | pmid:11928572 |
| Azuma Y et al. | 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-10 and IL-12 production by macrophages. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11327705 |
| Equils O et al. | Bacterial lipopolysaccharide activates HIV long terminal repeat through Toll-like receptor 4. | 2001 | J. Immunol. | pmid:11160291 |
| Wilmer WA et al. | A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11178960 |
| Kang SS et al. | Cyclooxygenase-2 inhibitory cerebrosides from phytolaccae radix. | 2001 | Chem. Pharm. Bull. | pmid:11253924 |
| Okayama Y et al. | A comparison of mediators released or generated by IFN-gamma-treated human mast cells following aggregation of Fc gamma RI or Fc epsilon RI. | 2001 | J. Immunol. | pmid:11254731 |
| Fahmi H et al. | Peroxisome proliferator--activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondrocytes. | 2001 | Arthritis Rheum. | pmid:11263774 |
| Hsieh FH et al. | T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4. | 2001 | J. Exp. Med. | pmid:11136826 |
| Tunaz H et al. | Prostaglandin biosynthesis by fat body from true armyworms, Pseudaletia unipuncta. | 2001 | Insect Biochem. Mol. Biol. | pmid:11222953 |
| Person EC et al. | Albumin regulates induction of peroxisome proliferator-activated receptor-gamma (PPARgamma) by 15-deoxy-delta(12-14)-prostaglandin J(2) in vitro and may be an important regulator of PPARgamma function in vivo. | 2001 | Endocrinology | pmid:11159824 |
| Reilly CM et al. | Prostaglandin J(2) inhibition of mesangial cell iNOS expression. | 2001 | Clin. Immunol. | pmid:11237557 |
| Kitamura Y et al. | Effects of 15-deoxy-delta(12,14) prostaglandin J(2) and interleukin-4 in Toll-like receptor-4-mutant glial cells. | 2001 | Eur. J. Pharmacol. | pmid:11164379 |
| Kadekaro M et al. | Central interactions between angiotensin II and PGD(2) in the regulation of vasopressin and oxytocin secretion in dehydrated rats. | 2001 | Brain Res. | pmid:11166690 |
| Szczeklik A et al. | Safety of a specific COX-2 inhibitor in aspirin-induced asthma. | 2001 | Clin. Exp. Allergy | pmid:11251623 |
| Nielsen PN et al. | Cetirizine inhibits skin reactions but not mediator release in immediate and developing late-phase allergic cutaneous reactions. A double-blind, placebo-controlled study. | 2001 | Clin. Exp. Allergy | pmid:11591187 |
| Satoh K et al. | Lipid peroxidation end products-responded induction of a preneoplastic marker enzyme glutathione S-transferase P-form (GST-P) in rat liver on admistration via the portal vein. | 2001 | Mutat. Res. | pmid:11600134 |
| Kitatani K et al. | Ceramide accelerates dephosphorylation of extracellular signal-regulated kinase 1/2 to decrease prostaglandin D(2) production in RBL-2H3 cells. | 2001 | Arch. Biochem. Biophys. | pmid:11697858 |
| Levonen AL et al. | Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells. | 2001 | Arterioscler. Thromb. Vasc. Biol. | pmid:11701476 |
| Ianaro A et al. | Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. | 2001 | FEBS Lett. | pmid:11707269 |
| Azuma Y et al. | 15-Deoxy-delta(12,14)-prostaglandin J2 is a negative regulator of macrophage functions. | 2001 | Int. Immunopharmacol. | pmid:11710539 |
| Robbins IM et al. | Increased levels of prostaglandin D(2) suggest macrophage activation in patients with primary pulmonary hypertension. | 2001 | Chest | pmid:11713147 |
| Jozkowicz A et al. | Prostaglandin-J2 induces synthesis of interleukin-8 by endothelial cells in a PPAR-gamma-independent manner. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11577781 |
| Garcia Palacios V et al. | Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Delta(12,14)-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728175 |
| Levine L | Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728177 |
| Tanimoto A et al. | Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells. | 2001 | FEBS Lett. | pmid:11728449 |
| Mizoguchi A et al. | Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11562489 |
| Inoue K et al. | Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11563856 |
| Clay CE et al. | Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells. | 2001 | J. Biol. Chem. | pmid:11668172 |
| Monneret G et al. | Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor. | 2001 | Blood | pmid:11535533 |
| Akrishnan VR and Menon VP | Potential role of antioxidants during ethanol-induced changes in the fatty acid composition and arachidonic acid metabolites in male Wistar rats. | 2001 | Cell Biol. Toxicol. | pmid:11504446 |
| Chiba Y et al. | PPARgamma ligands inhibit TNF-alpha-induced LOX-1 expression in cultured endothelial cells. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11511093 |
| Kozawa O et al. | Mechanism of prostaglandin D(2)-stimulated heat shock protein 27 induction in osteoblasts. | 2001 | Cell. Signal. | pmid:11483406 |
| Nakashiro KI et al. | Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells. | 2001 | Am. J. Pathol. | pmid:11485917 |
| Takashima T et al. | PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity. | 2001 | Int. J. Oncol. | pmid:11494023 |
| Rovin BH et al. | Cyclopentenone prostaglandins inhibit cytokine-induced nf-kappab activation and chemokine production by human mesangial cells. | 2001 | J. Am. Soc. Nephrol. | pmid:11461938 |
| Cernuda-Morollón E et al. | 15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit. | 2001 | J. Biol. Chem. | pmid:11466314 |
| Boyault S et al. | 15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways. | 2001 | FEBS Lett. | pmid:11457450 |
| Nishimura H et al. | Acute effects of prostaglandin D2 to induce airflow obstruction and airway microvascular leakage in guinea pigs: role of thromboxane A2 receptors. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11519790 |
| Clay CE et al. | Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells. | 2001 | J. Investig. Med. | pmid:11523697 |
| Hunter JG et al. | Peroxisome proliferator-activated receptor gamma ligands differentially modulate muscle cell differentiation and MyoD gene expression via peroxisome proliferator-activated receptor gamma -dependent and -independent pathways. | 2001 | J. Biol. Chem. | pmid:11477074 |