Wang P et al. |
The antagonistic actions of endogenous interleukin-1β and 15-deoxy-Δ12,14-prostaglandin J2 regulate the temporal synthesis of matrix metalloproteinase-9 in sheared chondrocytes. |
2012 |
J. Biol. Chem. |
pmid:22829602
|
Tokumoto H et al. |
An NADP-linked 15-hydroxyprostaglandin dehydrogenase specific for prostaglandin D2 from swine brain. |
1982 |
J. Biol. Chem. |
pmid:6958674
|
Nelson SM et al. |
Selenoprotein Expression in Macrophages Is Critical for Optimal Clearance of Parasitic Helminth Nippostrongylus brasiliensis. |
2016 |
J. Biol. Chem. |
pmid:26644468
|
Mathurin K et al. |
An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production. |
2011 |
J. Biol. Chem. |
pmid:21112970
|
Jiang JG et al. |
Peroxisome proliferator-activated receptor gamma-mediated transcriptional up-regulation of the hepatocyte growth factor gene promoter via a novel composite cis-acting element. |
2001 |
J. Biol. Chem. |
pmid:11292834
|
Cheng S et al. |
Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. |
2004 |
J. Biol. Chem. |
pmid:15023995
|
Kawamoto Y et al. |
Cyclopentenone prostaglandins as potential inducers of phase II detoxification enzymes. 15-deoxy-delta(12,14)-prostaglandin j2-induced expression of glutathione S-transferases. |
2000 |
J. Biol. Chem. |
pmid:10753940
|
Alvarez-Maqueda M et al. |
15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes. |
2004 |
J. Biol. Chem. |
pmid:15024026
|
Nie M et al. |
Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists. |
2005 |
J. Biol. Chem. |
pmid:15531761
|
Shimizu T et al. |
Specific binding of prostaglandin D2 to rat brain synaptic membrane. Occurrence, properties, and distribution. |
1982 |
J. Biol. Chem. |
pmid:6292197
|
Eling TE et al. |
Oxidation of glutathione to its thiyl free radical metabolite by prostaglandin H synthase. A potential endogenous substrate for the hydroperoxidase. |
1986 |
J. Biol. Chem. |
pmid:3007487
|
Koizumi T et al. |
Identification of a cis-regulatory element for delta 12-prostaglandin J2-induced expression of the rat heme oxygenase gene. |
1995 |
J. Biol. Chem. |
pmid:7665598
|
Wang YL et al. |
Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival. |
2002 |
J. Biol. Chem. |
pmid:12082115
|
Hirata Y et al. |
Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine. |
1988 |
J. Biol. Chem. |
pmid:3053696
|
Wilhelm D et al. |
SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development. |
2007 |
J. Biol. Chem. |
pmid:17277314
|
Amir-Moazami O et al. |
Phospholipid scramblase 1 modulates a selected set of IgE receptor-mediated mast cell responses through LAT-dependent pathway. |
2008 |
J. Biol. Chem. |
pmid:18579528
|
Lapointe DS and Olson MS |
Platelet-activating factor-stimulated hepatic glycogenolysis is not mediated through cyclooxygenase-derived metabolites of arachidonic acid. |
1989 |
J. Biol. Chem. |
pmid:2501299
|
Urade Y et al. |
Mast cells contain spleen-type prostaglandin D synthetase. |
1990 |
J. Biol. Chem. |
pmid:2403560
|
Bishop-Bailey D and Hla T |
Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. |
1999 |
J. Biol. Chem. |
pmid:10358055
|
Kwon G et al. |
Tumor necrosis factor alpha-induced pancreatic beta-cell insulin resistance is mediated by nitric oxide and prevented by 15-deoxy-Delta12,14-prostaglandin J2 and aminoguanidine. A role for peroxisome proliferator-activated receptor gamma activation and inos expression. |
1999 |
J. Biol. Chem. |
pmid:10373483
|
Lee TS et al. |
Induction of heme oxygenase-1 expression in murine macrophages is essential for the anti-inflammatory effect of low dose 15-deoxy-Delta 12,14-prostaglandin J2. |
2003 |
J. Biol. Chem. |
pmid:12642589
|
Richman JG et al. |
Nicotinic acid receptor agonists differentially activate downstream effectors. |
2007 |
J. Biol. Chem. |
pmid:17452318
|
Baek SJ et al. |
Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. |
2004 |
J. Biol. Chem. |
pmid:14662774
|
Schröder R et al. |
The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation. |
2009 |
J. Biol. Chem. |
pmid:19010788
|
Ho TC et al. |
15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53. |
2008 |
J. Biol. Chem. |
pmid:18718914
|
Liston TE and Roberts LJ |
Metabolic fate of radiolabeled prostaglandin D2 in a normal human male volunteer. |
1985 |
J. Biol. Chem. |
pmid:3863815
|
Hosoya T et al. |
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells. |
2005 |
J. Biol. Chem. |
pmid:15917255
|
Chen Y et al. |
Formation of reactive cyclopentenone compounds in vivo as products of the isoprostane pathway. |
1999 |
J. Biol. Chem. |
pmid:10196163
|
Xin X et al. |
Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. |
1999 |
J. Biol. Chem. |
pmid:10085162
|
Gao L et al. |
Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase. |
2003 |
J. Biol. Chem. |
pmid:12746435
|
Pérez-Sala D et al. |
Molecular basis for the direct inhibition of AP-1 DNA binding by 15-deoxy-Delta 12,14-prostaglandin J2. |
2003 |
J. Biol. Chem. |
pmid:14532268
|
Worley JR et al. |
Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid. |
2003 |
J. Biol. Chem. |
pmid:14534304
|
Lee S et al. |
Lipocalin-type prostaglandin D2 synthase protein regulates glial cell migration and morphology through myristoylated alanine-rich C-kinase substrate: prostaglandin D2-independent effects. |
2012 |
J. Biol. Chem. |
pmid:22275363
|
Shibata T et al. |
Thioredoxin as a molecular target of cyclopentenone prostaglandins. |
2003 |
J. Biol. Chem. |
pmid:12709421
|
Murakami M et al. |
Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells. |
1994 |
J. Biol. Chem. |
pmid:8071353
|
Shan ZZ et al. |
A potential role of 15-deoxy-delta(12,14)-prostaglandin J2 for induction of human articular chondrocyte apoptosis in arthritis. |
2004 |
J. Biol. Chem. |
pmid:15213234
|
Fitzpatrick FA and Wynalda MA |
Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro. |
1983 |
J. Biol. Chem. |
pmid:6578214
|
Pugliese G et al. |
Hepatic transformation of prostaglandin D2 to a new prostanoid, 9 alpha,11 beta-prostaglandin F2, that inhibits platelet aggregation and constricts blood vessels. |
1985 |
J. Biol. Chem. |
pmid:3863819
|
Clay CE et al. |
Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells. |
2001 |
J. Biol. Chem. |
pmid:11668172
|
Hilliard M et al. |
The anti-inflammatory prostaglandin 15-deoxy-delta(12,14)-PGJ2 inhibits CRM1-dependent nuclear protein export. |
2010 |
J. Biol. Chem. |
pmid:20457605
|
Paruchuri S et al. |
Leukotriene E4 activates peroxisome proliferator-activated receptor gamma and induces prostaglandin D2 generation by human mast cells. |
2008 |
J. Biol. Chem. |
pmid:18411276
|
Shiraya K et al. |
A novel transporter of SLC22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules. |
2010 |
J. Biol. Chem. |
pmid:20448048
|
Guo N et al. |
Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease. |
2010 |
J. Biol. Chem. |
pmid:20308056
|
Ishimoto T et al. |
Importance of the phospholipase D-initiated sequential pathway for arachidonic acid release and prostaglandin D2 generation by rat peritoneal mast cells. |
1996 |
J. Biochem. |
pmid:8902628
|
Kimura K et al. |
Modulation of platelet activating factor-induced glycogenolysis in the perfused rat liver after administration of endotoxin in vivo. |
1998 |
J. Biochem. |
pmid:9504421
|
Matsumoto K et al. |
Novel function of prostaglandins as inducers of gene expression of HGF and putative mediators of tissue regeneration. |
1995 |
J. Biochem. |
pmid:7608139
|
Sakamoto H et al. |
Effect of intracellular glutathione on the production of prostaglandin D2 in RBL-2H3 cells oxidized by tert-butyl hydroperoxide. |
1999 |
J. Biochem. |
pmid:9880802
|
Irikura D et al. |
Cloning, expression, crystallization, and preliminary X-ray analysis of recombinant mouse lipocalin-type prostaglandin D synthase, a somnogen-producing enzyme. |
2003 |
J. Biochem. |
pmid:12761195
|
Spatz M et al. |
Vasoactive peptides and prostaglandin D2 in human cerebromicrovascular endothelium. |
1994 |
J. Auton. Nerv. Syst. |
pmid:7836668
|
Hardy CC et al. |
Bronchoconstrictor and antibronchoconstrictor properties of inhaled prostacyclin in asthma. |
1988 |
J. Appl. Physiol. |
pmid:3288608
|
Cummings JJ |
Pulmonary vasodilator drugs decrease lung liquid production in fetal sheep. |
1995 |
J. Appl. Physiol. |
pmid:8567564
|
Hayaishi O |
Molecular genetic studies on sleep-wake regulation, with special emphasis on the prostaglandin D(2) system. |
2002 |
J. Appl. Physiol. |
pmid:11796702
|
Phillips GD and Holgate ST |
Interaction of inhaled LTC4 with histamine and PGD2 on airway caliber in asthma. |
1989 |
J. Appl. Physiol. |
pmid:2917934
|
Fredberg JJ et al. |
Tissue resistance and the contractile state of lung parenchyma. |
1993 |
J. Appl. Physiol. |
pmid:8482682
|
Kleeberger SR et al. |
Central role of cyclooxygenase in the response of canine peripheral airways to antigen. |
1986 |
J. Appl. Physiol. |
pmid:2430928
|
Emery DL et al. |
Prostaglandin D2 causes accumulation of eosinophils in the lumen of the dog trachea. |
1989 |
J. Appl. Physiol. |
pmid:2793725
|
Serio R and Daniel EE |
Thromboxane effects on canine trachealis neuromuscular function. |
1988 |
J. Appl. Physiol. |
pmid:2839451
|
Underwood DC et al. |
Blockade of thromboxane responses in the airway of the cat by SQ 29,548. |
1987 |
J. Appl. Physiol. |
pmid:2440845
|
Beasley RC et al. |
Effect of a thromboxane receptor antagonist on PGD2- and allergen-induced bronchoconstriction. |
1989 |
J. Appl. Physiol. |
pmid:2525122
|
Tilden SJ et al. |
Effects of OKY 1581 on bronchoconstrictor responses to arachidonic acid and PGH2. |
1987 |
J. Appl. Physiol. |
pmid:2954941
|
Myers AC et al. |
Influence of antigen on membrane properties of guinea pig bronchial ganglion neurons. |
1991 |
J. Appl. Physiol. |
pmid:1721906
|
Walmrath D et al. |
Intravascular anti-IgE challenge in perfused lungs: mediator release and vascular pressor response. |
1991 |
J. Appl. Physiol. |
pmid:1723406
|
Rajakulasingam K et al. |
Interactive effect of inhaled bradykinin with histamine and PGD2 in bronchial asthma. |
1993 |
J. Appl. Physiol. |
pmid:8307852
|
McMahon TJ et al. |
Influence of SQ 30741 on thromboxane receptor-mediated responses in the feline pulmonary vascular bed. |
1991 |
J. Appl. Physiol. |
pmid:1837015
|
Tamaoki J et al. |
Cholinergic neuromodulation by prostaglandin D2 in canine airway smooth muscle. |
1987 |
J. Appl. Physiol. |
pmid:2891674
|
Piprek RP |
Genetic mechanisms underlying male sex determination in mammals. |
2009 |
J. Appl. Genet. |
pmid:19875885
|
Tsutsumi S et al. |
Cerebrospinal fluid drainage through the diploic and spinal epidural veins. |
2015 |
J. Anat. |
pmid:26184099
|
Stamatakis K et al. |
Identification of novel protein targets for modification by 15-deoxy-Delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton. |
2006 |
J. Am. Soc. Nephrol. |
pmid:16291835
|
Ito H et al. |
PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis. |
2012 |
J. Am. Soc. Nephrol. |
pmid:22997255
|
Ruan XZ et al. |
PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway. |
2003 |
J. Am. Soc. Nephrol. |
pmid:12595494
|
Arici M et al. |
Stimulation of proximal tubular cell apoptosis by albumin-bound fatty acids mediated by peroxisome proliferator activated receptor-gamma. |
2003 |
J. Am. Soc. Nephrol. |
pmid:12506134
|
Rovin BH et al. |
Cyclopentenone prostaglandins inhibit cytokine-induced nf-kappab activation and chemokine production by human mesangial cells. |
2001 |
J. Am. Soc. Nephrol. |
pmid:11461938
|
Li Y et al. |
Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist. |
2007 |
J. Am. Chem. Soc. |
pmid:17691773
|
Yamaguchi S et al. |
Delta12-prostaglandin J2 as a product and ligand of human serum albumin: formation of an unusual covalent adduct at His146. |
2010 |
J. Am. Chem. Soc. |
pmid:20014793
|
VanderEnde DS and Morrow JD |
Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans after the application of cinnamic aldehyde. |
2001 |
J. Am. Acad. Dermatol. |
pmid:11423836
|
Reddy PH |
Inhibitors of mitochondrial fission as a therapeutic strategy for diseases with oxidative stress and mitochondrial dysfunction. |
2014 |
J. Alzheimers Dis. |
pmid:24413616
|
Ahluwalia P et al. |
Nedocromil sodium and levocabastine reduce the symptoms of conjunctival allergen challenge by different mechanisms. |
2001 |
J. Allergy Clin. Immunol. |
pmid:11544467
|
van der Linden PW et al. |
Insect-sting challenge in 138 patients: relation between clinical severity of anaphylaxis and mast cell activation. |
1992 |
J. Allergy Clin. Immunol. |
pmid:1629497
|
Pienkowski MM et al. |
Prostaglandin D2 and histamine during the immediate and the late-phase components of allergic cutaneous responses. |
1988 |
J. Allergy Clin. Immunol. |
pmid:3292634
|
Gervais FG et al. |
Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP. |
2001 |
J. Allergy Clin. Immunol. |
pmid:11742277
|
Ruzicka T et al. |
Inhibition of rat mast cell arachidonic acid cyclooxygenase by dapsone. |
1983 |
J. Allergy Clin. Immunol. |
pmid:6413566
|
Johnston SL et al. |
The effect of BAY u 3405, a thromboxane receptor antagonist, on prostaglandin D2-induced nasal blockage. |
1993 |
J. Allergy Clin. Immunol. |
pmid:8473679
|
Schleimer RP et al. |
Role of human basophils and mast cells in the pathogenesis of allergic diseases. |
1985 |
J. Allergy Clin. Immunol. |
pmid:2410478
|
Emery BE et al. |
The effect of IL-4 on human nasal mucosal responses. |
1992 |
J. Allergy Clin. Immunol. |
pmid:1430703
|
Fajt ML et al. |
Prostaglandin Dâ‚‚ pathway upregulation: relation to asthma severity, control, and TH2 inflammation. |
2013 |
J. Allergy Clin. Immunol. |
pmid:23506843
|
Schulman ES et al. |
Density heterogeneity of human lung mast cells. |
1988 |
J. Allergy Clin. Immunol. |
pmid:2455745
|
Shichijo M et al. |
Role of cyclic 3',5'-adenosine monophosphate in the regulation of chemical mediator release and cytokine production from cultured human mast cells. |
1999 |
J. Allergy Clin. Immunol. |
pmid:10329844
|
Bochner BS et al. |
Interleukin-1 is released at sites of human cutaneous allergic reactions. |
1990 |
J. Allergy Clin. Immunol. |
pmid:2262641
|
Doyle WJ et al. |
Physiologic responses to intranasal dose-response challenges with histamine, methacholine, bradykinin, and prostaglandin in adult volunteers with and without nasal allergy. |
1990 |
J. Allergy Clin. Immunol. |
pmid:2262647
|
Xue L et al. |
Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells. |
2014 |
J. Allergy Clin. Immunol. |
pmid:24388011
|
Norman PS |
The John Sheldon memorial lecture. Review of nasal therapy: update. |
1983 |
J. Allergy Clin. Immunol. |
pmid:6195204
|
Bochenek G et al. |
A controlled study of 9alpha,11beta-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge. |
2003 |
J. Allergy Clin. Immunol. |
pmid:12704352
|
Szczeklik W et al. |
Functional effects and gender association of COX-2 gene polymorphism G-765C in bronchial asthma. |
2004 |
J. Allergy Clin. Immunol. |
pmid:15316498
|
Schleimer RP et al. |
Inflammatory mediators and mechanisms of release from purified human basophils and mast cells. |
1984 |
J. Allergy Clin. Immunol. |
pmid:6208229
|
Nakahigashi K et al. |
PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis. |
2012 |
J. Allergy Clin. Immunol. |
pmid:22206772
|
Raphael GD et al. |
The pathophysiology of rhinitis. V. Sources of protein in allergen-induced nasal secretions. |
1991 |
J. Allergy Clin. Immunol. |
pmid:1712803
|
Awad JA et al. |
Detection of the major urinary metabolite of prostaglandin D2 in the circulation: demonstration of elevated levels in patients with disorders of systemic mast cell activation. |
1994 |
J. Allergy Clin. Immunol. |
pmid:8182221
|
Salari H et al. |
Involvement of immunologic mechanisms in a guinea pig model of western red cedar asthma. |
1994 |
J. Allergy Clin. Immunol. |
pmid:8182231
|
Proud D et al. |
Inflammatory mediator release on conjunctival provocation of allergic subjects with allergen. |
1990 |
J. Allergy Clin. Immunol. |
pmid:1692049
|
Miadonna A et al. |
Mediator release after endobronchial antigen challenge in patients with respiratory allergy. |
1990 |
J. Allergy Clin. Immunol. |
pmid:1692050
|