Armoni M et al. |
Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect. |
2003 |
J. Biol. Chem. |
pmid:12777391
|
Smith SA et al. |
Effects of peroxisome proliferator-activated receptor gamma ligands ciglitazone and 15-deoxy-delta 12,14-prostaglandin J2 on rat cultured cerebellar granule neuronal viability. |
2003 |
J. Neurosci. Res. |
pmid:12774315
|
Mitsumori S et al. |
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane derivatives. |
2003 |
J. Med. Chem. |
pmid:12773048
|
Mitsumori S et al. |
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 1. Bicyclo[2.2.1]heptane derivatives. |
2003 |
J. Med. Chem. |
pmid:12773047
|
Irikura D et al. |
Cloning, expression, crystallization, and preliminary X-ray analysis of recombinant mouse lipocalin-type prostaglandin D synthase, a somnogen-producing enzyme. |
2003 |
J. Biochem. |
pmid:12761195
|
Sommer A et al. |
A dominant role for extracellular glutathione S-transferase from Onchocerca volvulus is the production of prostaglandin D2. |
2003 |
Infect. Immun. |
pmid:12761146
|
Imaizumi T et al. |
15-deoxy-delta(12,14)-prostaglandin J2 inhibits IFN-gamma-induced galectin-9 expression in cultured human umbilical vein endothelial cells. |
2003 |
Int. Arch. Allergy Immunol. |
pmid:12759491
|
Lu S et al. |
Specific gene expression of isoforms in cyclooxygenase pathway to generate PGJ2 derivatives during the differentiation of 3T3-L1 adipocytes. |
2003 |
Adv. Exp. Med. Biol. |
pmid:12751756
|
Gao L et al. |
Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase. |
2003 |
J. Biol. Chem. |
pmid:12746435
|
Pierzchalska M et al. |
Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. |
2003 |
J. Allergy Clin. Immunol. |
pmid:12743569
|
Gosset P et al. |
Prostaglandin D2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. |
2003 |
J. Immunol. |
pmid:12734337
|
Paumi CM et al. |
Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. |
2003 |
Biochemistry |
pmid:12731885
|
Yee LD et al. |
The antiproliferative effects of PPARgamma ligands in normal human mammary epithelial cells. |
2003 |
Breast Cancer Res. Treat. |
pmid:12725418
|
Hata AN et al. |
Expression and molecular pharmacology of the mouse CRTH2 receptor. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12721327
|
Liu JD et al. |
Involvement of c-jun N-terminal kinase activation in 15-deoxy-delta12,14-prostaglandin J2-and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells. |
2003 |
Mol. Carcinog. |
pmid:12720296
|
Takata K et al. |
Possible involvement of small oligomers of amyloid-beta peptides in 15-deoxy-delta 12,14 prostaglandin J2-sensitive microglial activation. |
2003 |
J. Pharmacol. Sci. |
pmid:12719662
|
Tautenhahn A et al. |
Activation-induced PPARgamma expression sensitizes primary human T cells toward apoptosis. |
2003 |
J. Leukoc. Biol. |
pmid:12714582
|
Brown JR et al. |
Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD). |
2003 |
J. Leukoc. Biol. |
pmid:12714573
|
Kämpfer H et al. |
Cyclooxygenase-1-coupled prostaglandin biosynthesis constitutes an essential prerequisite for skin repair. |
2003 |
J. Invest. Dermatol. |
pmid:12713596
|
Zhuang H et al. |
Regulation of heme oxygenase expression by cyclopentenone prostaglandins. |
2003 |
Exp. Biol. Med. (Maywood) |
pmid:12709576
|
Shibata T et al. |
Thioredoxin as a molecular target of cyclopentenone prostaglandins. |
2003 |
J. Biol. Chem. |
pmid:12709421
|
Heinemann A et al. |
Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis. |
2003 |
J. Immunol. |
pmid:12707356
|
Cippitelli M et al. |
The cyclopentenone-type prostaglandin 15-deoxy-delta 12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms. |
2003 |
J. Immunol. |
pmid:12707336
|
Ando M et al. |
Retrovirally introduced prostaglandin D2 synthase suppresses lung injury induced by bleomycin. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12707014
|
Castaño E and Gil J |
15-deoxy-delta12,14 prostaglandin J2 synergizes with phorbol ester to induce proliferation in Swiss 3T3 cells independently of peroxisome proliferator-activated receptor gamma and PGD2 receptors. |
2003 |
J. Cell. Physiol. |
pmid:12704651
|
Bochenek G et al. |
A controlled study of 9alpha,11beta-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge. |
2003 |
J. Allergy Clin. Immunol. |
pmid:12704352
|
Komar CM and Curry TE |
Inverse relationship between the expression of messenger ribonucleic acid for peroxisome proliferator-activated receptor gamma and P450 side chain cleavage in the rat ovary. |
2003 |
Biol. Reprod. |
pmid:12700202
|
Zernecke A et al. |
Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction. |
2003 |
FASEB J. |
pmid:12692090
|
Kanbe E et al. |
DR1-like element in human topoisomerase IIalpha gene involved in enhancement of etoposide-induced apoptosis by PPARgamma ligand. |
2003 |
Exp. Hematol. |
pmid:12691917
|
Oliva JL et al. |
The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12684535
|
Mohri I et al. |
Hematopoietic prostaglandin D synthase is expressed in microglia in the developing postnatal mouse brain. |
2003 |
Glia |
pmid:12673832
|
Faveeuw C et al. |
Prostaglandin D2 inhibits the production of interleukin-12 in murine dendritic cells through multiple signaling pathways. |
2003 |
Eur. J. Immunol. |
pmid:12672054
|
Ye P et al. |
Activation of peroxisome proliferator-activated receptor alpha in human endothelial cells increases plasminogen activator inhibitor type-1 expression. |
2003 |
Chin. Med. J. |
pmid:12667383
|
Hammarstrom S et al. |
Novel eicosanoid activators of PPAR gamma formed by RAW 264.7 macrophage cultures. |
2002 |
Adv. Exp. Med. Biol. |
pmid:12664608
|
Diaz BL et al. |
Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells. |
2002 |
Adv. Exp. Med. Biol. |
pmid:12664562
|
Garg TK and Chang JY |
Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2. |
2003 |
BMC Ophthalmol |
pmid:12659653
|
Urade Y and Eguchi N |
[Sleep substances]. |
2003 |
No To Shinkei |
pmid:12649899
|
Sugimoto H et al. |
An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12649388
|
Houston KD et al. |
Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma. |
2003 |
Cancer Res. |
pmid:12649180
|
Lee TS et al. |
Induction of heme oxygenase-1 expression in murine macrophages is essential for the anti-inflammatory effect of low dose 15-deoxy-Delta 12,14-prostaglandin J2. |
2003 |
J. Biol. Chem. |
pmid:12642589
|
Lee CH and Edwards AM |
Differential expression of c-fos and c-myc protooncogenes by estrogens, xenobiotics and other growth-stimulatory agents in primary rat hepatocytes. |
2003 |
Arch. Toxicol. |
pmid:12632255
|
Tzanakakis GN et al. |
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. |
2002 |
Int J Gastrointest Cancer |
pmid:12630766
|
Hashimoto K et al. |
Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells. |
2002 |
Int J Gastrointest Cancer |
pmid:12630765
|
Taba Y et al. |
15-deoxy-delta 12,14-prostaglandin J2 and laminar fluid shear stress stabilize c-IAP1 in vascular endothelial cells. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12623786
|
Wanichkul T et al. |
Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells. |
2003 |
Fertil. Steril. |
pmid:12620489
|
Kajekar R et al. |
Role of cyclooxygenase activation and prostaglandins in antigen-induced excitability changes of bronchial parasympathetic ganglia neurons. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12618420
|
Kanehara H et al. |
Thrombomodulin expression by THP-1 but not by vascular endothelial cells is upregulated by pioglitazone. |
2002 |
Thromb. Res. |
pmid:12617986
|
Qin C et al. |
Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. |
2003 |
Cancer Res. |
pmid:12615709
|
Abe M et al. |
GATA-6 is involved in PPARgamma-mediated activation of differentiated phenotype in human vascular smooth muscle cells. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12615657
|
Hirano A et al. |
Arachidonic acid-induced channel- and carrier-type ion transport across planar bilayer lipid membranes. |
2003 |
Anal Sci |
pmid:12608744
|
Jung KM et al. |
Activation of p38 mitogen-activated protein kinase and activator protein-1 during the promotion of neurite extension of PC-12 cells by 15-deoxy-delta12,14-prostaglandin J2. |
2003 |
Mol. Pharmacol. |
pmid:12606768
|
Hinz B et al. |
15-Deoxy-Delta(12,14)-prostaglandin J2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-gamma-independent mechanism. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12604364
|
Cuzzocrea S et al. |
The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat. |
2003 |
Br. J. Pharmacol. |
pmid:12598422
|
Ruan XZ et al. |
PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway. |
2003 |
J. Am. Soc. Nephrol. |
pmid:12595494
|
Patel HJ et al. |
Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy. |
2003 |
J. Immunol. |
pmid:12594295
|
Park EJ et al. |
15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia. |
2003 |
J. Biol. Chem. |
pmid:12584205
|
Gibbons H et al. |
Hypothermia suppresses inducible nitric oxide synthase and stimulates cyclooxygenase-2 in lipopolysaccharide stimulated BV-2 cells. |
2003 |
Brain Res. Mol. Brain Res. |
pmid:12573534
|
Söderström M et al. |
Novel prostaglandin D(2)-derived activators of peroxisome proliferator-activated receptor-gamma are formed in macrophage cell cultures. |
2003 |
Biochim. Biophys. Acta |
pmid:12573447
|
Tanaka H et al. |
Possible involvement of prostaglandins F(2alpha) and D(2) in acetylcholine-induced positive inotropy in isolated mouse left atria. |
2003 |
Pharmacology |
pmid:12571412
|
Moore RM et al. |
Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells. |
2003 Feb-Mar |
Placenta |
pmid:12566244
|
Castrillo A et al. |
Potentiation of protein kinase C zeta activity by 15-deoxy-delta(12,14)-prostaglandin J(2) induces an imbalance between mitogen-activated protein kinases and NF-kappa B that promotes apoptosis in macrophages. |
2003 |
Mol. Cell. Biol. |
pmid:12556480
|
Desmond JC et al. |
The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs. |
2003 |
Cancer Res. |
pmid:12543809
|
Farrow B and Evers BM |
Activation of PPARgamma increases PTEN expression in pancreatic cancer cells. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12535639
|
Li LH and Ku BS |
[Regulation of SWS by hormones and cytokines]. |
2000 |
Sheng Li Ke Xue Jin Zhan |
pmid:12532764
|
Calnek DS et al. |
Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12524224
|
Neuschäfer-Rube F et al. |
Identification by site-directed mutagenesis of amino acids contributing to ligand-binding specificity or signal transduction properties of the human FP prostanoid receptor. |
2003 |
Biochem. J. |
pmid:12519077
|
Pang L et al. |
Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors. |
2003 |
J. Immunol. |
pmid:12517972
|
Weber SM et al. |
Inhibition of IFN-gamma -induced STAT1 activation by 15- deoxy-Delta 12,14-prostaglandin J2. |
2003 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:12517740
|
Arici M et al. |
Stimulation of proximal tubular cell apoptosis by albumin-bound fatty acids mediated by peroxisome proliferator activated receptor-gamma. |
2003 |
J. Am. Soc. Nephrol. |
pmid:12506134
|
Nithipatikom K et al. |
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion. |
2002 |
Clin. Exp. Metastasis |
pmid:12498388
|
Winnett G et al. |
Prostaglandin J2 metabolites inhibit aromatase activity by redox-sensitive mechanisms: potential implications for breast cancer therapy. |
2003 |
Int. J. Cancer |
pmid:12494466
|
Li L et al. |
RasGRP4 regulates the expression of prostaglandin D2 in human and rat mast cell lines. |
2003 |
J. Biol. Chem. |
pmid:12493770
|
Satoh T |
[Neurotrophin-like low molecular weight compounds]. |
2002 |
Nippon Yakurigaku Zasshi |
pmid:12491808
|
Monneret G et al. |
15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12490611
|
Larsen P et al. |
Calcium-stimulated short-circuit currents in the canine proximal colonic epithelium: effects of DK-PGD2, a metabolite of prostaglandin D2. |
2002 |
Can. J. Physiol. Pharmacol. |
pmid:12489928
|
Satoh T and Watanabe Y |
[Cyclopentenone prostaglandin derivatives as neuroprotective compounds]. |
2002 |
Tanpakushitsu Kakusan Koso |
pmid:12486935
|
Sawyer N et al. |
Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2. |
2002 |
Br. J. Pharmacol. |
pmid:12466225
|
Kalla R et al. |
Loss of microglial ramification in microglia-astrocyte cocultures: involvement of adenylate cyclase, calcium, phosphatase, and Gi-protein systems. |
2003 |
Glia |
pmid:12465045
|
Gueck T et al. |
Influence of vitamin E on mast cell mediator release. |
2002 |
Vet. Dermatol. |
pmid:12464062
|
Badawi AF and Badr MZ |
Expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-gamma and levels of prostaglandin E2 and 15-deoxy-delta12,14-prostaglandin J2 in human breast cancer and metastasis. |
2003 |
Int. J. Cancer |
pmid:12455057
|
Nikitakis NG et al. |
15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells. |
2002 |
Br. J. Cancer |
pmid:12454768
|
Yang X et al. |
Hypoxic induction of cox-2 regulates proliferation of human pulmonary artery smooth muscle cells. |
2002 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12444028
|
Fahmi H et al. |
15d-PGJ(2) is acting as a 'dual agent' on the regulation of COX-2 expression in human osteoarthritic chondrocytes. |
2002 |
Osteoarthr. Cartil. |
pmid:12435328
|
Shahbazian A et al. |
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine. |
2002 |
Br. J. Pharmacol. |
pmid:12429577
|
Kubata BK et al. |
A key role for old yellow enzyme in the metabolism of drugs by Trypanosoma cruzi. |
2002 |
J. Exp. Med. |
pmid:12417633
|
Jawerbaum A et al. |
Modulation of nitric oxide concentration and lipid metabolism by 15-deoxy Delta12,14prostaglandin J2 in embryos from control and diabetic rats during early organogenesis. |
2002 |
Reproduction |
pmid:12417000
|
Kim SY et al. |
Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses. |
2002 |
Phytother Res |
pmid:12410540
|
Imaizumi T et al. |
15-Deoxy-D12,14-prostaglandin J2 inhibits CX3CL1/fractalkine expression in human endothelial cells. |
2002 |
Immunol. Cell Biol. |
pmid:12406386
|
Clay CE et al. |
15-Deoxy-delta12,14-prostaglandin J2-induced apoptosis does not require PPARgamma in breast cancer cells. |
2002 |
J. Lipid Res. |
pmid:12401880
|
Suzuki-Nishimura T and Uchida MK |
Prostaglandin D2 generation by rat peritoneal mast cells stimulated with Datura stramonium agglutinin and its inhibition by haptenic sugar and wheat germ agglutinin. |
2002 |
Jpn. J. Pharmacol. |
pmid:12396030
|
Piliponsky AM et al. |
Non-IgE-dependent activation of human lung- and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor. |
2003 |
Blood |
pmid:12393403
|
Hu VY et al. |
COX-2 and prostanoid expression in micturition pathways after cyclophosphamide-induced cystitis in the rat. |
2003 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:12388444
|
Zhang J et al. |
15-Deoxy-prostaglandin J(2) inhibits PDGF-A and -B chain expression in human vascular endothelial cells independent of PPAR gamma. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12379230
|
Higashi N et al. |
A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma. |
2002 |
Clin. Exp. Allergy |
pmid:12372129
|
Vitzthum H et al. |
Gene expression of prostanoid forming enzymes along the rat nephron. |
2002 |
Kidney Int. |
pmid:12371957
|
Lappas M et al. |
Regulation of proinflammatory cytokines in human gestational tissues by peroxisome proliferator-activated receptor-gamma: effect of 15-deoxy-Delta(12,14)-PGJ(2) and troglitazone. |
2002 |
J. Clin. Endocrinol. Metab. |
pmid:12364456
|
Campo PA et al. |
Translational regulation of cyclin D1 by 15-deoxy-delta(12,14)-prostaglandin J(2). |
2002 |
Cell Growth Differ. |
pmid:12354750
|
Suzuki K and Uyeda M |
Inhibitory properties of antitumor prostaglandins against topoisomerases. |
2002 |
Biosci. Biotechnol. Biochem. |
pmid:12353631
|
Eligini S et al. |
15-deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial cells: evidence for ERK1/2 signaling pathway blockade. |
2002 |
Thromb. Haemost. |
pmid:12353085
|
Skolnik PR et al. |
Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. |
2002 |
J. Acquir. Immune Defic. Syndr. |
pmid:12352144
|