Kim HY and Kim HS |
Upregulation of MIP-2 (CXCL2) expression by 15-deoxy-Delta(12,14)-prostaglandin J(2) in mouse peritoneal macrophages. |
2007 |
Immunol. Cell Biol. |
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Hepatic ischemia-reperfusion induces renal heme oxygenase-1 via NF-E2-related factor 2 in rats and mice. |
2007 |
Mol. Pharmacol. |
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Rahman A et al. |
Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats. |
2007 |
Eur. J. Pharmacol. |
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Haack M et al. |
Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers. |
2007 |
Sleep |
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Antiplatelet effect of NQ12: a possible mechanism through the arachidonic acid cascade. |
2007 |
J. Pharmacol. Sci. |
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15-deoxy-Delta12,14-prostaglandin J2 inhibits transcriptional activity of estrogen receptor-alpha via covalent modification of DNA-binding domain. |
2007 |
Cancer Res. |
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Nose-to-brain delivery of TS-002, prostaglandin D2 analogue. |
2007 |
J Drug Target |
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15-deoxy-Delta12,14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors. |
2007 |
J. Immunol. |
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PGD(2) DP1 receptor protects brain from ischemia-reperfusion injury. |
2007 |
Eur. J. Neurosci. |
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Divergent effects of prostaglandin receptor signaling on neuronal survival. |
2007 |
Neurosci. Lett. |
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IL-13 induces expression of CD36 in human monocytes through PPARgamma activation. |
2007 |
Eur. J. Immunol. |
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Neuroendocrine functions of melanocytes: beyond the skin-deep melanin maker. |
2007 |
Tohoku J. Exp. Med. |
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Development of enzyme-linked immunosorbent assay for prostaglandin D2 using the stable isosteric analogue as a hapten mimic and its application. |
2007 |
Prostaglandins Other Lipid Mediat. |
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15d-PGJ2 stimulates HO-1 expression through p38 MAP kinase and Nrf-2 pathway in rat vascular smooth muscle cells. |
2007 |
Toxicol. Appl. Pharmacol. |
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Accumulation of hypoxia-inducible factor-1alpha through a novel electrophilic, thiol antioxidant-sensitive mechanism. |
2007 |
Cell. Signal. |
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15d-PGJ2 induces apoptosis of mouse oligodendrocyte precursor cells. |
2007 |
J Neuroinflammation |
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Inhibition of adhesive interaction between multiple myeloma and bone marrow stromal cells by PPARgamma cross talk with NF-kappaB and C/EBP. |
2007 |
Blood |
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15-Deoxy-delta 12,14-prostaglandin J2 (15d-PGJ 2) sensitizes human leukemic HL-60 cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through Akt downregulation. |
2007 |
Apoptosis |
pmid:17786557
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Iikura M et al. |
IL-33 can promote survival, adhesion and cytokine production in human mast cells. |
2007 |
Lab. Invest. |
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Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells. |
2007 |
Exp. Cell Res. |
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15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways. |
2007 |
Exp. Cell Res. |
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Prostaglandin D2 suppresses human NK cell function via signaling through D prostanoid receptor. |
2007 |
J. Immunol. |
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Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist. |
2007 |
J. Am. Chem. Soc. |
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Modulation of human airway smooth muscle migration by lipid mediators and Th-2 cytokines. |
2007 |
Am. J. Respir. Cell Mol. Biol. |
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Anti-inflammatory effects of PPAR-gamma agonists directly correlate with PPAR-gamma expression during acute pancreatitis. |
2006 Sep-Oct |
J. Gastrointest. Surg. |
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The thiazolidinedione drug troglitazone up-regulates nitric oxide synthase expression in vascular endothelial cells. |
2006 Sep-Oct |
J. Diabetes Complicat. |
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Rat basophilic leukemia cells (RBL-2H3) generate prostaglandin D2 (PGD2) after regulated upon activation, normal T-cell expressed and secreted (RANTES) activation. |
2006 Oct-Dec |
Int. J. Biol. Markers |
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Lappas M et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) and troglitazone regulation of the release of phospholipid metabolites, inflammatory cytokines and proteases from human gestational tissues. |
2006 Nov-Dec |
Placenta |
pmid:16434095
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Urade Y |
Twenty-fifth anniversary of the discovery of somnogenic activity of prostaglandin D2: sleep research directed by Osamu Hayaishi. |
2006 May-Jun |
IUBMB Life |
pmid:16754308
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Okano M et al. |
Presence and characterization of prostaglandin D2-related molecules in nasal mucosa of patients with allergic rhinitis. |
2006 May-Jun |
Am J Rhinol |
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Mast cell inhibitor R112 is well tolerated and affects prostaglandin D2 but not other mediators, symptoms, or nasal volumes in a nasal challenge model of allergic rhinitis. |
2006 May-Jun |
Allergy Asthma Proc |
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Kim SJ et al. |
Effects of methyl gallate on arachidonic acid metabolizing enzymes: Cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. |
2006 |
Arch. Pharm. Res. |
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Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity. |
2006 |
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15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis. |
2006 |
Mol. Cancer Ther. |
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Wang XS and Lau HY |
Beta-adrenoceptor-mediated inhibition of mediator release from human peripheral blood-derived mast cells. |
2006 |
Clin. Exp. Pharmacol. Physiol. |
pmid:16895550
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Prostaglandin D2 inhibits TGF-beta1-induced epithelial-to-mesenchymal transition in MDCK cells. |
2006 |
Am. J. Physiol. Renal Physiol. |
pmid:16896186
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Chaffer CL et al. |
PPARgamma-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma. |
2006 |
BMC Cancer |
pmid:16519808
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Pérez S et al. |
The 2-series prostaglandins suppress VLDL secretion in an inflammatory condition-dependent manner in primary rat hepatocytes. |
2006 |
Biochim. Biophys. Acta |
pmid:16545597
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Wise H |
Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells. |
2006 |
Eur. J. Pharmacol. |
pmid:16545798
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Functional characterization of human mast cells cultured from adult peripheral blood. |
2006 |
Int. Immunopharmacol. |
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Activation of peroxisome proliferator-activated receptor-gamma decreases pancreatic cancer cell invasion through modulation of the plasminogen activator system. |
2006 |
Mol. Cancer Res. |
pmid:16547153
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Fu YG et al. |
Inhibition of gastric cancer cells associated angiogenesis by 15d-prostaglandin J2 through the downregulation of angiopoietin-1. |
2006 |
Cancer Lett. |
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Wung BS et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) suppresses IL-6-induced STAT3 phosphorylation via electrophilic reactivity in endothelial cells. |
2006 |
Life Sci. |
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On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2. |
2006 |
Mol. Pharmacol. |
pmid:16418339
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High levels of filamentous actin and apoptosis correlate with mast cell refractoriness under alloxan-evoked diabetes. |
2006 |
Life Sci. |
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Effects of 15d-PGJ(2) on VEGF-induced angiogenic activities and expression of VEGF receptors in endothelial cells. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16647637
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Jin MH et al. |
Anti-inflammatory activity of Ailanthus altissima in ovalbumin-induced lung inflammation. |
2006 |
Biol. Pharm. Bull. |
pmid:16651713
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Herlong JL and Scott TR |
Positioning prostanoids of the D and J series in the immunopathogenic scheme. |
2006 |
Immunol. Lett. |
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Merwald H et al. |
Induction of the 72-kilodalton heat shock protein and protection from ultraviolet B-induced cell death in human keratinocytes by repetitive exposure to heat shock or 15-deoxy-delta(12,14)-prostaglandin J2. |
2006 |
Cell Stress Chaperones |
pmid:16572732
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Sato TA and Mitchell MD |
Preferential production of prostaglandin D2 by lipopolysaccharide stimulated human choriodecidual explants. |
2006 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:16380246
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Arnold R and König W |
Peroxisome-proliferator-activated receptor-gamma agonists inhibit the release of proinflammatory cytokines from RSV-infected epithelial cells. |
2006 |
Virology |
pmid:16330064
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Kohno S et al. |
Inhibition of skin sclerosis by 15deoxy delta12,14-prostaglandin J2 and retrovirally transfected prostaglandin D synthase in a mouse model of bleomycin-induced scleroderma. |
2006 |
Biomed. Pharmacother. |
pmid:16337105
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Xie Y et al. |
Differentiation-dependent regulation of the cyclooxygenase cascade during adipogenesis suggests a complex role for prostaglandins. |
2006 |
Diabetes Obes Metab |
pmid:16367886
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Ogburn KD et al. |
Prostaglandin J2 reduces catechol-O-methyltransferase activity and enhances dopamine toxicity in neuronal cells. |
2006 |
Neurobiol. Dis. |
pmid:16406650
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15d-prostaglandin J2 protects brain from ischemia-reperfusion injury. |
2006 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:16385084
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Yucel-Lindberg T et al. |
Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts. |
2006 |
Cell. Signal. |
pmid:16766159
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Peroxisome proliferator-activated receptor-gamma1 is dephosphorylated and degraded during BAY 11-7085-induced synovial fibroblast apoptosis. |
2006 |
J. Biol. Chem. |
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Sugimoto M et al. |
Role of COX-1 and COX-2 on skin PGs biosynthesis by mechanical scratching in mice. |
2006 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:16815697
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Schwartz MS et al. |
Determination of a prostaglandin D2 antagonist and its acyl glucuronide metabolite in human plasma by high performance liquid chromatography with tandem mass spectrometric detection--a lack of MS/MS selectivity between a glucuronide conjugate and a phase I metabolite. |
2006 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:16716772
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Na HK and Surh YJ |
Transcriptional regulation via cysteine thiol modification: a novel molecular strategy for chemoprevention and cytoprotection. |
2006 |
Mol. Carcinog. |
pmid:16673384
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BrazÃs P et al. |
Dermal microdialysis in the dog: in vivo assessment of the effect of cyclosporin A on cutaneous histamine and prostaglandin D2 release. |
2006 |
Vet. Dermatol. |
pmid:16674731
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Hickson-Bick DL et al. |
The response of neonatal rat ventricular myocytes to lipopolysaccharide-induced stress. |
2006 |
Shock |
pmid:16680021
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Son MJ et al. |
Naturally occurring biflavonoid, ochnaflavone, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. |
2006 |
Arch. Pharm. Res. |
pmid:16681032
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Wang WM et al. |
[Effects of peroxisome proliferators-activated receptor gamma agonists on transforming growth factor-beta1 and Smads signal pathway: experiment with rat renal fibroblasts]. |
2006 |
Zhonghua Yi Xue Za Zhi |
pmid:16681946
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Sun K et al. |
PPAR gamma inhibits growth of rat hepatic stellate cells and TGF beta-induced connective tissue growth factor expression. |
2006 |
Acta Pharmacol. Sin. |
pmid:16723090
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Neuronal expression of peroxisome proliferator-activated receptor-gamma (PPARgamma) and 15d-prostaglandin J2--mediated protection of brain after experimental cerebral ischemia in rat. |
2006 |
Brain Res. |
pmid:16725118
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Lee S et al. |
Rosiglitazone ameliorates cisplatin-induced renal injury in mice. |
2006 |
Nephrol. Dial. Transplant. |
pmid:16728429
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Rajasingh J and Bright JJ |
15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells. |
2006 |
Exp. Cell Res. |
pmid:16737695
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Bate C et al. |
Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells. |
2006 |
Neuropharmacology |
pmid:16289250
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Bellows CF et al. |
Modulation of macrophage nitric oxide production by prostaglandin D2. |
2006 |
J. Surg. Res. |
pmid:16289592
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Helliwell RJ et al. |
Gestational age-dependent up-regulation of prostaglandin D synthase (PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta. |
2006 |
J. Clin. Endocrinol. Metab. |
pmid:16291703
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Stamatakis K et al. |
Identification of novel protein targets for modification by 15-deoxy-Delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton. |
2006 |
J. Am. Soc. Nephrol. |
pmid:16291835
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Benkirane K et al. |
PPAR-gamma inhibits ANG II-induced cell growth via SHIP2 and 4E-BP1. |
2006 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:16155101
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Zhang YF et al. |
Peroxisome proliferator-activated receptor-gamma is expressed by rat peritoneal mesothelial cells: its potential role in peritoneal cavity local defense. |
2006 |
Am. J. Nephrol. |
pmid:17183189
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Fernández PL |
[Stress and inflammatory bowell disease (I.B.D). Therapeutic strategies]. |
2006 |
An R Acad Nac Med (Madr) |
pmid:17172222
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Pereira MP et al. |
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms. |
2006 |
J. Cereb. Blood Flow Metab. |
pmid:16034372
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Tanaka H et al. |
Polymer-assisted solution-phase synthesis and neurite-outgrowth-promoting activity of 15-deoxy-delta(12,14)-PGJ2 derivatives. |
2006 |
Chem Asian J |
pmid:17441107
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PPAR-gamma ligands and amino acid deprivation promote apoptosis of melanoma, prostate, and breast cancer cells. |
2006 |
Cancer Lett. |
pmid:15979236
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Chiba T et al. |
Prostaglandin D2 induces IL-8 and GM-CSF by bronchial epithelial cells in a CRTH2-independent pathway. |
2006 |
Int. Arch. Allergy Immunol. |
pmid:16940740
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Yu X et al. |
Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-Delta12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase. |
2006 |
J. Biol. Chem. |
pmid:16857669
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Chen ZH et al. |
Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. |
2006 |
J. Biol. Chem. |
pmid:16565077
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Horiguchi T et al. |
Cyclooxygenase-2 mediates the development of cortical spreading depression-induced tolerance to transient focal cerebral ischemia in rats. |
2006 |
Neuroscience |
pmid:16567054
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Siddhivarn C et al. |
Prostaglandin D2 pathway and peroxisome proliferator-activated receptor gamma-1 expression are induced by mechanical loading in an osteoblastic cell line. |
2006 |
J. Periodont. Res. |
pmid:16499711
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Coyle AT and Kinsella BT |
Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells. |
2006 |
Biochem. Pharmacol. |
pmid:16499875
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Makino N et al. |
Peroxisome proliferator-activated receptor-gamma ligands attenuate brain natriuretic peptide production and affect remodeling in cardiac fibroblasts in reoxygenation after hypoxia. |
2006 |
Cell Biochem. Biophys. |
pmid:16456235
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Figarella K et al. |
Prostaglandin-induced programmed cell death in Trypanosoma brucei involves oxidative stress. |
2006 |
Cell Death Differ. |
pmid:16456581
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Belvisi MG et al. |
Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation. |
2006 |
Eur. J. Pharmacol. |
pmid:16458290
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Rolin S et al. |
Prostanoids as pharmacological targets in COPD and asthma. |
2006 |
Eur. J. Pharmacol. |
pmid:16458293
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Masuda H et al. |
15-deoxy-Delta12,14-prostaglandin J2 attenuates development of cyclophosphamide-induced cystitis in rats. |
2006 |
Urology |
pmid:16461118
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Lee E et al. |
Anti-asthmatic activity of an ethanol extract from Saururus chinensis. |
2006 |
Biol. Pharm. Bull. |
pmid:16462020
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Raetz CR et al. |
Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. |
2006 |
J. Lipid Res. |
pmid:16479018
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Nakahata Y et al. |
The in vitro real-time oscillation monitoring system identifies potential entrainment factors for circadian clocks. |
2006 |
BMC Mol. Biol. |
pmid:16483373
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Lee JJ et al. |
Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization. |
2006 |
Vascul. Pharmacol. |
pmid:16916624
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Ulven T and Kostenis E |
Targeting the prostaglandin D2 receptors DP and CRTH2 for treatment of inflammation. |
2006 |
Curr Top Med Chem |
pmid:16918458
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Theiner G et al. |
The mast cell mediator PGD2 suppresses IL-12 release by dendritic cells leading to Th2 polarized immune responses in vivo. |
2006 |
Immunobiology |
pmid:16920486
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Urade Y and Mohri I |
[Sleep and brain function]. |
2006 |
No To Hattatsu |
pmid:16986732
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Kim EH and Surh YJ |
15-deoxy-Delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors. |
2006 |
Biochem. Pharmacol. |
pmid:16987499
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Diaz BL et al. |
Group V secretory phospholipase A2 amplifies the induction of cyclooxygenase 2 and delayed prostaglandin D2 generation in mouse bone marrow culture-derived mast cells in a strain-dependent manner. |
2006 |
Biochim. Biophys. Acta |
pmid:17064958
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Qin S et al. |
Protection of RPE cells from oxidative injury by 15-deoxy-delta12,14-prostaglandin J2 by augmenting GSH and activating MAPK. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:17065531
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Gyles SL et al. |
A dominant role for chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants. |
2006 |
Immunology |
pmid:17067313
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