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Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2. |
2009 |
Leukemia |
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Evidence that 13-14 di-hydro, 15-keto prostaglandin D(2)-induced airway eosinophilia in guinea-pigs is independent of interleukin-5. |
2009 |
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2009 |
Shock |
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2009 |
Immunology |
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The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse. |
2009 |
Endocrinology |
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Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen. |
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J Neuroinflammation |
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Clin. Exp. Allergy |
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A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation. |
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Int. Immunol. |
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Int. Immunol. |
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Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. |
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Endocrinology |
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Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs. |
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Quantitative characterization of prostaglandins in the uterus of early pregnant cattle. |
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Reproduction |
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A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep. |
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Clin. Exp. Allergy |
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Neuroscience |
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Prostaglandins Leukot. Essent. Fatty Acids |
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Prostaglandin D2 produced by hematopoietic prostaglandin D synthase contributes to LPS-induced fever. |
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Prostaglandins Other Lipid Mediat. |
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The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation. |
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Cancer Res. |
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Neoplasia |
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PLoS ONE |
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Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators. |
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Oxidative stress in the thyroid gland: from harmlessness to hazard depending on the iodine content. |
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Endocrinology |
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Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, PPARgamma agonists, differentially regulate cigarette smoke-mediated pro-inflammatory cytokine release in monocytes/macrophages. |
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Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}. |
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Blood |
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Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis. |
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Am. J. Nephrol. |
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Comparison of short term in vitro cultured human mast cells from different progenitors - Peripheral blood-derived progenitors generate highly mature and functional mast cells. |
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15-Deoxy-delta12,14-prostaglandin-J(2) up-regulates cyclooxygenase-2 but inhibits prostaglandin-E(2) production through a thiol antioxidant-sensitive mechanism. |
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J. Gastroenterol. Hepatol. |
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15-deoxy-Delta12,14-prostaglandin J2 inhibits INF-gamma-induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells. |
2008 |
Nephrol. Dial. Transplant. |
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Cancer Detect. Prev. |
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Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthma. |
2008 |
Allergol Int |
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TGF-beta1 attenuates mediator release and de novo Kit expression by human skin mast cells through a Smad-dependent pathway. |
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Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2. |
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Arthritis Rheum. |
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Secretory phospholipases A(2) isolated from Bothrops asper and from Crotalus durissus terrificus snake venoms induce distinct mechanisms for biosynthesis of prostaglandins E2 and D2 and expression of cyclooxygenases. |
2008 |
Toxicon |
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Effects of natural ligands of PPARgamma on lipid metabolism in placental tissues from healthy and diabetic rats. |
2008 |
Mol. Hum. Reprod. |
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Prevention of mast cell activation disorder-associated clinical sequelae of excessive prostaglandin D(2) production. |
2008 |
Int. Arch. Allergy Immunol. |
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Clinical and biochemical effects of a combination botanical product (ClearGuard) for allergy: a pilot randomized double-blind placebo-controlled trial. |
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Nutr J |
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Enhancement of axonal regeneration by in vitro conditioning and its inhibition by cyclopentenone prostaglandins. |
2008 |
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A negative regulator of delayed prostaglandin D2 production in mouse mast cells. |
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Biochim. Biophys. Acta |
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Niacin-induced "flush" involves release of prostaglandin D2 from mast cells and serotonin from platelets: evidence from human cells in vitro and an animal model. |
2008 |
J. Pharmacol. Exp. Ther. |
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Ciglitazone and 15d-PGJ2 induced suicidal erythrocyte death. |
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Cell. Physiol. Biochem. |
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PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells. |
2008 |
Br. J. Cancer |
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The 15-deoxy-delta 12,14-prostaglandin J2 suppresses monocyte chemoattractant protein-1 expression in IFN-gamma-stimulated astrocytes through induction of MAPK phosphatase-1. |
2008 |
J. Immunol. |
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Prostaglandin D2 induces heme oxygenase-1 mRNA expression through the DP2 receptor. |
2008 |
Biochem. Biophys. Res. Commun. |
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The flavonoid luteolin inhibits niacin-induced flush. |
2008 |
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15-Deoxy-Delta12,14-prostaglandin J2 induces chemokine expression, oxidative stress and microfilament reorganization in bovine mammary epithelial cells. |
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J. Dairy Res. |
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Prostaglandin D2 inhibits the production of IFN-gamma by invariant NK T cells: consequences in the control of B16 melanoma. |
2008 |
J. Immunol. |
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Met-Arg-Trp derived from Rubisco lowers blood pressure via prostaglandin D(2)-dependent vasorelaxation in spontaneously hypertensive rats. |
2008 |
Peptides |
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Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
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The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. |
2008 |
Glia |
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Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages. |
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Antiplatelet activity of epigallocatechin gallate is mediated by the inhibition of PLCgamma2 phosphorylation, elevation of PGD2 production, and maintaining calcium-ATPase activity. |
2008 |
J. Cardiovasc. Pharmacol. |
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[Structure and function of prostaglandin D synthase]. |
2008 |
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Human liver dihydrodiol dehydrogenase 1-catalyzed reaction generating 9alpha,11beta-prostaglandin F2 from prostaglandin D2 followed by micellar electrokinetic chromatography. |
2008 |
J Sep Sci |
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