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Leukemia |
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Lipid metabolite levels of prostaglandin D2 and eicosapentaenoic acid recovered from bronchoalveolar lavage fluid correlate with lung function of chronic obstructive pulmonary disease patients and controls. |
2009 |
Electrophoresis |
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The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse. |
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Endocrinology |
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Inhibition of prostaglandin D synthase suppresses muscular necrosis. |
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Clin. Exp. Allergy |
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Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase. |
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Oncogene |
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Reproduction |
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PLoS ONE |
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Endocrinology |
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Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. |
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J Clin Pharmacol |
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Cancer Res. |
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Neoplasia |
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Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia. |
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PLoS ONE |
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Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators. |
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Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, PPARgamma agonists, differentially regulate cigarette smoke-mediated pro-inflammatory cytokine release in monocytes/macrophages. |
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An improved LC-MS/MS method for the quantification of prostaglandins E(2) and D(2) production in biological fluids. |
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Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain. |
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AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells. |
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Molecular characterization of peroxisome proliferator-activated receptors (PPARs) and their gene expression in the differentiating adipocytes of red sea bream Pagrus major. |
2008 |
Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |
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15-deoxy-Delta12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferase. |
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15-deoxy-delta 12,14-prostaglandin J(2) inhibits the synthesis of the acute phase protein SIP24 in cartilage: Involvement of COX-2 in resolution of inflammation. |
2008 |
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Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways. |
2008 |
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Lipopolysaccharide induces macrophage migration via prostaglandin D(2) and prostaglandin E(2). |
2008 |
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Constitutive Smad signaling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferator-activated receptor-gamma. |
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Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury. |
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Shock |
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Heme oxygenase-1 expression is down-regulated by angiotensin II and under hypertension in human neutrophils. |
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Regulation of TLR2 expression by prostaglandins in brain glia. |
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PGJ2 antagonizes NF-kappaB-induced HIV-1 LTR activation in colonic epithelial cells. |
2008 |
Virology |
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15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes. |
2008 |
Blood |
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Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation. |
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Anti-allergic activity of an ethanol extract from Salviae miltiorrhiza. |
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Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway. |
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Opposite roles of STAT and PPARgamma in the induction of p21WAF1 expression by IL-13 in human peripheral blood monocytes. |
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Carbon monoxide-prostaglandin E2 interaction in the hypothalamic circulation. |
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Neuroreport |
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Gene |
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The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury. |
2008 |
Glia |
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Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages. |
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Antiplatelet activity of epigallocatechin gallate is mediated by the inhibition of PLCgamma2 phosphorylation, elevation of PGD2 production, and maintaining calcium-ATPase activity. |
2008 |
J. Cardiovasc. Pharmacol. |
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PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo. |
2008 |
Invest New Drugs |
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Activation of peroxisome proliferator-activated receptor gamma inhibits TNF-alpha-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocyte chemoattractant protein-1 expression. |
2008 |
Bone |
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Rubimetide (Met-Arg-Trp) derived from Rubisco exhibits anxiolytic-like activity via the DP1 receptor in male ddY mice. |
2008 |
Peptides |
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Central prostaglandin D(2) stimulates food intake via the neuropeptide Y system in mice. |
2008 |
FEBS Lett. |
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[Structure and function of prostaglandin D synthase]. |
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Human liver dihydrodiol dehydrogenase 1-catalyzed reaction generating 9alpha,11beta-prostaglandin F2 from prostaglandin D2 followed by micellar electrokinetic chromatography. |
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J Sep Sci |
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Effects of laropiprant on nicotinic acid-induced flushing in patients with dyslipidemia. |
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Am. J. Cardiol. |
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BAG-1 inhibits PPARgamma-induced cell death, but not PPARgamma-induced transcription, cell cycle arrest or differentiation in breast cancer cells. |
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Up-regulation of heme oxygenase-1 expression through the Rac1/NADPH oxidase/ROS/p38 signaling cascade mediates the anti-inflammatory effect of 15-deoxy-delta 12,14-prostaglandin J2 in murine macrophages. |
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Activation of cannabinoid receptors prevents antigen-induced asthma-like reaction in guinea pigs. |
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[Prostaglandin D2: new roles in the embryonic and pathological gonad]. |
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Salicylamide-induced anaphylaxis: increased urinary leukotriene E4 and prostaglandin D2 metabolite. |
2008 |
Allergy |
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