Souza SC et al. |
TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes. |
2003 |
J. Cell. Biochem. |
pmid:12898507
|
Zhuang H et al. |
Prostaglandins of J series control heme oxygenase expression: potential significance in modulating neuroinflammation. |
2003 |
Ann. N. Y. Acad. Sci. |
pmid:12853315
|
Pestel S et al. |
Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. |
2003 |
Biochem. Pharmacol. |
pmid:12906929
|
Pritts EA et al. |
Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element. |
2003 |
Fertil. Steril. |
pmid:12909507
|
Nencioni A et al. |
Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling. |
2003 |
J. Immunol. |
pmid:14607914
|
Date M et al. |
15-Deoxy-delta12,14-prostaglandin J2, a ligand for peroxisome proliferators-activated receptor-gamma, induces apoptosis in human hepatoma cells. |
2003 |
Liver Int. |
pmid:14986820
|
Liu H et al. |
PPARgamma ligands and ATRA inhibit the invasion of human breast cancer cells in vitro. |
2003 |
Breast Cancer Res. Treat. |
pmid:12779083
|
Mitsumori S et al. |
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 1. Bicyclo[2.2.1]heptane derivatives. |
2003 |
J. Med. Chem. |
pmid:12773047
|
Mitsumori S et al. |
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane derivatives. |
2003 |
J. Med. Chem. |
pmid:12773048
|
Ide T et al. |
Activation of nuclear receptors by prostaglandins. |
2003 |
Thromb. Res. |
pmid:14592554
|
Yagami T et al. |
Novel binding sites of 15-deoxy-Delta12,14-prostaglandin J2 in plasma membranes from primary rat cortical neurons. |
2003 |
Exp. Cell Res. |
pmid:14597421
|
Caivano M et al. |
15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide. |
2003 |
J. Biol. Chem. |
pmid:14557273
|
Oliva JL et al. |
The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12684535
|
Paumi CM et al. |
Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. |
2003 |
Biochemistry |
pmid:12731885
|
Monneret G et al. |
15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12490611
|
Takano H and Komuro I |
Roles of peroxisome proliferator-activated receptor gamma in cardiovascular disease. |
2002 Jan-Feb |
J. Diabetes Complicat. |
pmid:11872377
|
Monneret G et al. |
15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils. |
2002 |
J. Immunol. |
pmid:11907120
|
Hayaishi O and Urade Y |
Prostaglandin D2 in sleep-wake regulation: recent progress and perspectives. |
2002 |
Neuroscientist |
pmid:11843094
|
Harris SG and Phipps RP |
Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells. |
2002 |
Immunology |
pmid:11849312
|
Masamune A et al. |
Ligands of peroxisome proliferator-activated receptor-gamma induce apoptosis in AR42J cells. |
2002 |
Pancreas |
pmid:11854617
|
Diab A et al. |
Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis. |
2002 |
J. Immunol. |
pmid:11859145
|
Adams IR and McLaren A |
Sexually dimorphic development of mouse primordial germ cells: switching from oogenesis to spermatogenesis. |
2002 |
Development |
pmid:11874911
|
Mellor EA et al. |
Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists. |
2002 |
J. Exp. Med. |
pmid:11877481
|
Xie S et al. |
15 deoxy delta12,14 PGJ2 induces procoagulant activity in cultured human endothelial cells. |
2002 |
Thromb. Haemost. |
pmid:11916086
|
Rovin BH et al. |
15-Deoxy-Delta12,14-prostaglandin J2 regulates mesangial cell proliferation and death. |
2002 |
Kidney Int. |
pmid:11918736
|
Mondoro TH and Vostal JG |
Cold temperatures reduce the sensitivity of stored platelets to disaggregating agents. |
2002 |
Platelets |
pmid:11918832
|
Noverr MC et al. |
Production of prostaglandins and leukotrienes by pathogenic fungi. |
2002 |
Infect. Immun. |
pmid:11748207
|
Schoppee PD et al. |
Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells. |
2002 |
Biol. Reprod. |
pmid:11751282
|
Fujitani Y et al. |
Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice. |
2002 |
J. Immunol. |
pmid:11751991
|
Yagami T et al. |
Human group IIA secretory phospholipase A2 induces neuronal cell death via apoptosis. |
2002 |
Mol. Pharmacol. |
pmid:11752212
|
Fu Y et al. |
Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12, 14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages. |
2002 |
Atherosclerosis |
pmid:11755918
|
Chen GG et al. |
Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer. |
2002 |
Life Sci. |
pmid:12269390
|
Suzuki R and Freed AN |
Heparin inhibits hyperventilation-induced late-phase hyperreactivity in dogs. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:11779726
|
Shibata T et al. |
15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. |
2002 |
J. Biol. Chem. |
pmid:11786541
|
Masamune A et al. |
Ligands of peroxisome proliferator-activated receptor-gamma block activation of pancreatic stellate cells. |
2002 |
J. Biol. Chem. |
pmid:11606585
|
Chen SY et al. |
15-Deoxy-delta12,14-prostaglandin J2 induces apoptosis of a thyroid papillary cancer cell line (CG3 cells) through increasing intracellular iron and oxidative stress. |
2002 |
Anticancer Drugs |
pmid:12187333
|
Yamamoto S et al. |
Agents that elevate cyclic AMP induce receptor phosphorylation primarily at serine 331 in HEK 293 cells overexpressing human thromboxane receptor alpha. |
2002 |
Biochem. Pharmacol. |
pmid:12147288
|
Sakurai S et al. |
Retinal capillary pericyte proliferation and c-Fos mRNA induction by prostaglandin D2 through the cAMP response element. |
2002 |
Invest. Ophthalmol. Vis. Sci. |
pmid:12147615
|
Saito S et al. |
Prostaglandin D2 and reproduction. |
2002 |
Am. J. Reprod. Immunol. |
pmid:12148545
|
Miyazaki Y et al. |
Inhibitory effect of peroxisome proliferator-activated receptor-gamma ligands on the expression of IgE heavy chain germline transcripts in the human B cell line DND39. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12150985
|
Fernández-Tomé Mdel C et al. |
Phospholipase C inhibitors and prostaglandins differentially regulate phosphatidylcholine synthesis in rat renal papilla. Evidence of compartmental regulation of CTP:phosphocholine cytidylyltransferase and CDP-choline:1,2-diacylglycerol cholinephosphotransferase. |
2002 |
Biochim. Biophys. Acta |
pmid:12117562
|
Kohyama T et al. |
PGD(2) modulates fibroblast-mediated native collagen gel contraction. |
2002 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12204901
|
Nencioni A et al. |
Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor gamma. |
2002 |
J. Immunol. |
pmid:12133943
|
Kudoh I et al. |
[Prostanoids and acute lung injury]. |
2002 |
Masui |
pmid:12134647
|
Meier CA et al. |
Regulation of the interleukin-1 receptor antagonist in THP-1 cells by ligands of the peroxisome proliferator-activated receptor gamma. |
2002 |
Cytokine |
pmid:12160520
|
Kwak BR et al. |
PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells. |
2002 |
Circ. Res. |
pmid:11861426
|
Shimada T et al. |
Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. |
2002 |
Gut |
pmid:11950812
|
Pestel S et al. |
Inhibition by prostaglandin E(2) of anaphylatoxin C5a- but not zymosan-induced prostanoid release from rat Kupffer cells. |
2002 |
Lab. Invest. |
pmid:11950903
|
Nishida K et al. |
Inhibition of human chondrosarcoma cell growth via apoptosis by peroxisome proliferator-activated receptor-gamma. |
2002 |
Br. J. Cancer |
pmid:11953889
|
Finck BN and Johnson RW |
Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11959686
|
Bureau F et al. |
A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-kappa B inhibition. |
2002 |
J. Immunol. |
pmid:11994490
|
Nosjean O and Boutin JA |
Natural ligands of PPARgamma: are prostaglandin J(2) derivatives really playing the part? |
2002 |
Cell. Signal. |
pmid:11955950
|
Yu Y et al. |
Conjugated linoleic acid decreases production of pro-inflammatory products in macrophages: evidence for a PPAR gamma-dependent mechanism. |
2002 |
Biochim. Biophys. Acta |
pmid:12020636
|
Mujumdar VS et al. |
Mechanism of constrictive vascular remodeling by homocysteine: role of PPAR. |
2002 |
Am. J. Physiol., Cell Physiol. |
pmid:11940516
|
Padilla J et al. |
Human B lymphocytes and B lymphomas express PPAR-gamma and are killed by PPAR-gamma agonists. |
2002 |
Clin. Immunol. |
pmid:11987982
|
Natarajan C and Bright JJ |
Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. |
2002 |
Genes Immun. |
pmid:11960303
|
Cuzzocrea S et al. |
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation. |
2002 |
Mol. Pharmacol. |
pmid:11961117
|
Kojima K et al. |
Effect of PPARgamma ligands on the viability of gastric epithelial cells. |
2002 |
Aliment. Pharmacol. Ther. |
pmid:11966526
|
Lee B et al. |
Prostaglandin D synthase in the prenatal ovine brain and effects of its inhibition with selenium chloride on fetal sleep/wake activity in utero. |
2002 |
J. Neurosci. |
pmid:12097519
|
Wang YL et al. |
Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival. |
2002 |
J. Biol. Chem. |
pmid:12082115
|
Huang WC et al. |
Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929. |
2002 |
Exp. Cell Res. |
pmid:12083801
|
Kondo M et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12032289
|
Krishnaswamy G et al. |
Regulation of eosinophil-active cytokine production from human cord blood-derived mast cells. |
2002 |
J. Interferon Cytokine Res. |
pmid:12034046
|
Sawano H et al. |
15-Deoxy-Delta12,14-prostaglandin J2 inhibits IL-1beta-induced cyclooxygenase-2 expression in mesangial cells. |
2002 |
Kidney Int. |
pmid:12028436
|
Zander T et al. |
Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma. |
2002 |
J. Neurochem. |
pmid:12065618
|
Yagami T et al. |
Group IB secretory phospholipase A2 induces neuronal cell death via apoptosis. |
2002 |
J. Neurochem. |
pmid:12065654
|
Fujino T et al. |
Effects of the prostanoids on the proliferation or hypertrophy of cultured murine aortic smooth muscle cells. |
2002 |
Br. J. Pharmacol. |
pmid:12055131
|
Ward C et al. |
Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism. |
2002 |
J. Immunol. |
pmid:12055237
|
Wayman NS et al. |
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. |
2002 |
FASEB J. |
pmid:12087064
|
Lennon AM et al. |
MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive oxygenated species. |
2002 |
J. Biol. Chem. |
pmid:12052825
|
Lappas M et al. |
Regulation of proinflammatory cytokines in human gestational tissues by peroxisome proliferator-activated receptor-gamma: effect of 15-deoxy-Delta(12,14)-PGJ(2) and troglitazone. |
2002 |
J. Clin. Endocrinol. Metab. |
pmid:12364456
|
Skolnik PR et al. |
Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. |
2002 |
J. Acquir. Immune Defic. Syndr. |
pmid:12352144
|
Eligini S et al. |
15-deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial cells: evidence for ERK1/2 signaling pathway blockade. |
2002 |
Thromb. Haemost. |
pmid:12353085
|
Suzuki K and Uyeda M |
Inhibitory properties of antitumor prostaglandins against topoisomerases. |
2002 |
Biosci. Biotechnol. Biochem. |
pmid:12353631
|
Haslmayer P et al. |
The peroxisome proliferator-activated receptor gamma ligand 15-deoxy-Delta12,14-prostaglandin J2 induces vascular endothelial growth factor in the hormone-independent prostate cancer cell line PC 3 and the urinary bladder carcinoma cell line 5637. |
2002 |
Int. J. Oncol. |
pmid:12239635
|
Clay CE et al. |
15-Deoxy-delta12,14-prostaglandin J2-induced apoptosis does not require PPARgamma in breast cancer cells. |
2002 |
J. Lipid Res. |
pmid:12401880
|
Imaizumi T et al. |
15-Deoxy-D12,14-prostaglandin J2 inhibits CX3CL1/fractalkine expression in human endothelial cells. |
2002 |
Immunol. Cell Biol. |
pmid:12406386
|
Kim SY et al. |
Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses. |
2002 |
Phytother Res |
pmid:12410540
|
Jawerbaum A et al. |
Modulation of nitric oxide concentration and lipid metabolism by 15-deoxy Delta12,14prostaglandin J2 in embryos from control and diabetic rats during early organogenesis. |
2002 |
Reproduction |
pmid:12417000
|
Kubata BK et al. |
A key role for old yellow enzyme in the metabolism of drugs by Trypanosoma cruzi. |
2002 |
J. Exp. Med. |
pmid:12417633
|
Nencioni A et al. |
Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-gamma-independent mechanism: regulation by inflammatory and T cell-derived stimuli. |
2002 |
Exp. Hematol. |
pmid:12225793
|
Menè P |
Prostaglandin D2 : a Cinderella of vascular cell biology? |
2002 |
J. Hypertens. |
pmid:12131515
|
Hunt MJ and Tyagi SC |
Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation. |
2002 |
Am. J. Physiol., Cell Physiol. |
pmid:12225971
|
Negoro H et al. |
Endogenous prostaglandin D2 synthesis reduces an increase in plasminogen activator inhibitor-1 following interleukin stimulation in bovine endothelial cells. |
2002 |
J. Hypertens. |
pmid:12131531
|
Stubbs VE et al. |
Indomethacin causes prostaglandin D(2)-like and eotaxin-like selective responses in eosinophils and basophils. |
2002 |
J. Biol. Chem. |
pmid:11980903
|
Suzuki-Nishimura T and Uchida MK |
Prostaglandin D2 generation by rat peritoneal mast cells stimulated with Datura stramonium agglutinin and its inhibition by haptenic sugar and wheat germ agglutinin. |
2002 |
Jpn. J. Pharmacol. |
pmid:12396030
|
Hashimoto K et al. |
Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells. |
2002 |
Int J Gastrointest Cancer |
pmid:12630765
|
Diaz BL et al. |
Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells. |
2002 |
Adv. Exp. Med. Biol. |
pmid:12664562
|
Hammarstrom S et al. |
Novel eicosanoid activators of PPAR gamma formed by RAW 264.7 macrophage cultures. |
2002 |
Adv. Exp. Med. Biol. |
pmid:12664608
|
Whigham LD et al. |
Decreased antigen-induced eicosanoid release in conjugated linoleic acid-fed guinea pigs. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11893615
|
Satoh T |
[Neurotrophin-like low molecular weight compounds]. |
2002 |
Nippon Yakurigaku Zasshi |
pmid:12491808
|
Gueck T et al. |
Influence of vitamin E on mast cell mediator release. |
2002 |
Vet. Dermatol. |
pmid:12464062
|
Sawyer N et al. |
Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2. |
2002 |
Br. J. Pharmacol. |
pmid:12466225
|
Yang X et al. |
Hypoxic induction of cox-2 regulates proliferation of human pulmonary artery smooth muscle cells. |
2002 |
Am. J. Respir. Cell Mol. Biol. |
pmid:12444028
|
Nikitakis NG et al. |
15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells. |
2002 |
Br. J. Cancer |
pmid:12454768
|
Fahmi H et al. |
15d-PGJ(2) is acting as a 'dual agent' on the regulation of COX-2 expression in human osteoarthritic chondrocytes. |
2002 |
Osteoarthr. Cartil. |
pmid:12435328
|
Vitzthum H et al. |
Gene expression of prostanoid forming enzymes along the rat nephron. |
2002 |
Kidney Int. |
pmid:12371957
|
Higashi N et al. |
A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma. |
2002 |
Clin. Exp. Allergy |
pmid:12372129
|
Zhang J et al. |
15-Deoxy-prostaglandin J(2) inhibits PDGF-A and -B chain expression in human vascular endothelial cells independent of PPAR gamma. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12379230
|
Nithipatikom K et al. |
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion. |
2002 |
Clin. Exp. Metastasis |
pmid:12498388
|