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Adipophilin is a sensitive marker for lipid loading in human blood monocytes. |
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Biochim. Biophys. Acta |
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Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans after the application of cinnamic aldehyde. |
2001 |
J. Am. Acad. Dermatol. |
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Comparative actions of insulin sensitizers on ion channels in vascular smooth muscle. |
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15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways. |
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Cyclopentenone prostaglandins inhibit cytokine-induced nf-kappab activation and chemokine production by human mesangial cells. |
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15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit. |
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Peroxisome proliferator-activated receptor gamma ligands differentially modulate muscle cell differentiation and MyoD gene expression via peroxisome proliferator-activated receptor gamma -dependent and -independent pathways. |
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15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors. |
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Mechanism of prostaglandin D(2)-stimulated heat shock protein 27 induction in osteoblasts. |
2001 |
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Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells. |
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Profile of eicosanoids produced by human saphenous vein endothelial cells and the effect of dietary fatty acids. |
2001 |
Prostaglandins Leukot. Essent. Fatty Acids |
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PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity. |
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Potential role of antioxidants during ethanol-induced changes in the fatty acid composition and arachidonic acid metabolites in male Wistar rats. |
2001 |
Cell Biol. Toxicol. |
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PPARgamma ligands inhibit TNF-alpha-induced LOX-1 expression in cultured endothelial cells. |
2001 |
Biochem. Biophys. Res. Commun. |
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Acute effects of prostaglandin D2 to induce airflow obstruction and airway microvascular leakage in guinea pigs: role of thromboxane A2 receptors. |
2001 |
Prostaglandins Other Lipid Mediat. |
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Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells. |
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J. Investig. Med. |
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Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor. |
2001 |
Blood |
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Control of cell cycle by metabolites of prostaglandin D2 through a non-cAMP mediated mechanism. |
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Life Sci Adv Exp Clin Endocrinol |
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Nedocromil sodium and levocabastine reduce the symptoms of conjunctival allergen challenge by different mechanisms. |
2001 |
J. Allergy Clin. Immunol. |
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Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
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Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists. |
2001 |
Biochem. Biophys. Res. Commun. |
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Prostaglandin-J2 induces synthesis of interleukin-8 by endothelial cells in a PPAR-gamma-independent manner. |
2001 |
Prostaglandins Other Lipid Mediat. |
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Peroxisome proliferator-activated receptor gamma activators inhibit cardiac hypertrophy in cardiac myocytes. |
2001 |
Circulation |
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Cetirizine inhibits skin reactions but not mediator release in immediate and developing late-phase allergic cutaneous reactions. A double-blind, placebo-controlled study. |
2001 |
Clin. Exp. Allergy |
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Lipid peroxidation end products-responded induction of a preneoplastic marker enzyme glutathione S-transferase P-form (GST-P) in rat liver on admistration via the portal vein. |
2001 |
Mutat. Res. |
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Ligands of peroxisome proliferator-activated receptor-gamma block activation of pancreatic stellate cells. |
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Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells. |
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15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells. |
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Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet. |
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Life Sci. |
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Ceramide accelerates dephosphorylation of extracellular signal-regulated kinase 1/2 to decrease prostaglandin D(2) production in RBL-2H3 cells. |
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Arch. Biochem. Biophys. |
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Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells. |
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Arterioscler. Thromb. Vasc. Biol. |
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Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature. |
2001 |
Am. J. Physiol. Renal Physiol. |
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Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. |
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FEBS Lett. |
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15-Deoxy-delta(12,14)-prostaglandin J2 is a negative regulator of macrophage functions. |
2001 |
Int. Immunopharmacol. |
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Increased levels of prostaglandin D(2) suggest macrophage activation in patients with primary pulmonary hypertension. |
2001 |
Chest |
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Expression of adipogenesis markers in a murine stromal cell line treated with 15-deoxy Delta(12,14)-prostaglandin J2, interleukin-11, 9-cis retinoic acid and vitamin K2. |
2001 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:11728175
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Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors. |
2001 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:11728177
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Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells. |
2001 |
FEBS Lett. |
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The peroxisome proliferator-activated receptor gamma is an inhibitor of ErbBs activity in human breast cancer cells. |
2001 |
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Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP. |
2001 |
J. Allergy Clin. Immunol. |
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PPAR-gamma ligands modulate effects of LPS in stimulated rat synovial fibroblasts. |
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Am. J. Physiol., Cell Physiol. |
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A protective role for cyclooxygenase-2 in drug-induced liver injury in mice. |
2001 |
Chem. Res. Toxicol. |
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Production of prostaglandins and leukotrienes by pathogenic fungi. |
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Infect. Immun. |
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Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells. |
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Biol. Reprod. |
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Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice. |
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Human group IIA secretory phospholipase A2 induces neuronal cell death via apoptosis. |
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Mol. Pharmacol. |
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Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12, 14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages. |
2002 |
Atherosclerosis |
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Heparin inhibits hyperventilation-induced late-phase hyperreactivity in dogs. |
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Am. J. Respir. Crit. Care Med. |
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15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells. |
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Prostaglandins Other Lipid Mediat. |
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15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. |
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Molecular genetic studies on sleep-wake regulation, with special emphasis on the prostaglandin D(2) system. |
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Cutting edge: agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2. |
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15-deoxy-Delta 12,14-PGJ2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway. |
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J. Immunol. |
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Regulation of prostaglandin endoperoxide synthase-2 and IL-6 expression in mouse bone marrow-derived mast cells by exogenous but not endogenous prostanoids. |
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J. Immunol. |
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Cyclooxygenase-2 regulates apoptosis in rat epididymis through prostaglandin D2. |
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Biol. Reprod. |
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Lipopolysaccharide-induced release of arachidonic acid and prostaglandins in liver macrophages: regulation by Group IV cytosolic phospholipase A2, but not by Group V and Group IIA secretory phospholipase A2. |
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Cell. Signal. |
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Accumulation of CRTH2-positive T-helper 2 and T-cytotoxic 2 cells at implantation sites of human decidua in a prostaglandin D(2)-mediated manner. |
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Mol. Hum. Reprod. |
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Synergistic effect of 4-hydroxynonenal and PPAR ligands in controlling human leukemic cell growth and differentiation. |
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Free Radic. Biol. Med. |
pmid:11827749
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Prostaglandin D2 in sleep-wake regulation: recent progress and perspectives. |
2002 |
Neuroscientist |
pmid:11843094
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Prostaglandin D(2), its metabolite 15-d-PGJ(2), and peroxisome proliferator activated receptor-gamma agonists induce apoptosis in transformed, but not normal, human T lineage cells. |
2002 |
Immunology |
pmid:11849312
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Ligands of peroxisome proliferator-activated receptor-gamma induce apoptosis in AR42J cells. |
2002 |
Pancreas |
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Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis. |
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J. Immunol. |
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PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells. |
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Circ. Res. |
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Prostaglandins as modulators of immunity. |
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Trends Immunol. |
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Peroxisome proliferator-activated receptor gamma activators inhibit MMP-1 production in human synovial fibroblasts likely by reducing the binding of the activator protein 1. |
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Osteoarthr. Cartil. |
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Roles of peroxisome proliferator-activated receptor gamma in cardiovascular disease. |
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J. Diabetes Complicat. |
pmid:11872377
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Sexually dimorphic development of mouse primordial germ cells: switching from oogenesis to spermatogenesis. |
2002 |
Development |
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Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists. |
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Prostaglandin biosynthesis by midgut tissue isolated from the tobacco hornworm, Manduca sexta. |
2002 |
Insect Biochem. Mol. Biol. |
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Streptozotocin-pancreatic damage in the rat: modulatory effect of 15-deoxy delta12,14-prostaglandin j(2) on nitridergic and prostanoid pathway. |
2002 |
Nitric Oxide |
pmid:11890746
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Decreased antigen-induced eicosanoid release in conjugated linoleic acid-fed guinea pigs. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11893615
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15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils. |
2002 |
J. Immunol. |
pmid:11907120
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15 deoxy delta12,14 PGJ2 induces procoagulant activity in cultured human endothelial cells. |
2002 |
Thromb. Haemost. |
pmid:11916086
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15-Deoxy-Delta12,14-prostaglandin J2 regulates mesangial cell proliferation and death. |
2002 |
Kidney Int. |
pmid:11918736
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Mondoro TH and Vostal JG |
Cold temperatures reduce the sensitivity of stored platelets to disaggregating agents. |
2002 |
Platelets |
pmid:11918832
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Nicolaidis S et al. |
[Variations of hypothalamic and cortical prostaglandins and monoamines reveal transitions in arousal states: microdialysis study in the rat]. |
2001 |
Rev. Neurol. (Paris) |
pmid:11924034
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[Prostaglandin D2: biosynthesis, biological properties and participation in bronchial asthma]. |
2001 |
Pol. Arch. Med. Wewn. |
pmid:11928572
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Inhibition of inducible prostaglandin E(2) synthase by 15-deoxy-Delta(12,14)-prostaglandin J(2) and polyunsaturated fatty acids. |
2002 |
Biochem. Pharmacol. |
pmid:11931852
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Hong JT et al. |
Inhibitory effect of peroxisome proliferator-activated receptor gamma agonist on ochratoxin A-induced cytotoxicity and activation of transcription factors in cultured rat embryonic midbrain cells. |
2002 |
J. Toxicol. Environ. Health Part A |
pmid:11936221
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Mujumdar VS et al. |
Mechanism of constrictive vascular remodeling by homocysteine: role of PPAR. |
2002 |
Am. J. Physiol., Cell Physiol. |
pmid:11940516
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Shimada T et al. |
Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. |
2002 |
Gut |
pmid:11950812
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Pestel S et al. |
Inhibition by prostaglandin E(2) of anaphylatoxin C5a- but not zymosan-induced prostanoid release from rat Kupffer cells. |
2002 |
Lab. Invest. |
pmid:11950903
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Nishida K et al. |
Inhibition of human chondrosarcoma cell growth via apoptosis by peroxisome proliferator-activated receptor-gamma. |
2002 |
Br. J. Cancer |
pmid:11953889
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Natural ligands of PPARgamma: are prostaglandin J(2) derivatives really playing the part? |
2002 |
Cell. Signal. |
pmid:11955950
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Finck BN and Johnson RW |
Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11959686
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Natarajan C and Bright JJ |
Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. |
2002 |
Genes Immun. |
pmid:11960303
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The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation. |
2002 |
Mol. Pharmacol. |
pmid:11961117
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Kojima K et al. |
Effect of PPARgamma ligands on the viability of gastric epithelial cells. |
2002 |
Aliment. Pharmacol. Ther. |
pmid:11966526
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Kershenovich A et al. |
Angiotensin II does not mediate the pressor response to PGD2 (icv). |
2000 |
J Renin Angiotensin Aldosterone Syst |
pmid:11967813
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Selective inhibition of cyclooxygenase-2 expression by 15-deoxy-Delta(12,14)(12,14)-prostaglandin J(2) in activated human astrocytes, but not in human brain macrophages. |
2002 |
J. Immunol. |
pmid:11971025
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Han S and Sidell N |
Peroxisome-proliferator-activated-receptor gamma (PPARgamma) independent induction of CD36 in THP-1 monocytes by retinoic acid. |
2002 |
Immunology |
pmid:11972632
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Jeng JH et al. |
Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase. |
2002 |
Free Radic. Biol. Med. |
pmid:11978487
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Ushikubi F and Narumiya S |
[The roles of the prostanoids played in the body]. |
2002 |
Nippon Yakurigaku Zasshi |
pmid:11979724
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Stubbs VE et al. |
Indomethacin causes prostaglandin D(2)-like and eotaxin-like selective responses in eosinophils and basophils. |
2002 |
J. Biol. Chem. |
pmid:11980903
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Padilla J et al. |
Human B lymphocytes and B lymphomas express PPAR-gamma and are killed by PPAR-gamma agonists. |
2002 |
Clin. Immunol. |
pmid:11987982
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A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-kappa B inhibition. |
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J. Immunol. |
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Jozkowicz A et al. |
Ligands of peroxisome proliferator-activated receptor-gamma increase the generation of vascular endothelial growth factor in vascular smooth muscle cells and in macrophages. |
2000 |
Acta Biochim. Pol. |
pmid:11996104
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Kohyama T et al. |
Prostaglandin D2 inhibits fibroblast migration. |
2002 |
Eur. Respir. J. |
pmid:11998998
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Cloned human EP1 prostanoid receptor pharmacology characterized using radioligand binding techniques. |
2002 |
J. Pharm. Pharmacol. |
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Activation of the mouse heme oxygenase-1 gene by 15-deoxy-Delta(12,14)-prostaglandin J(2) is mediated by the stress response elements and transcription factor Nrf2. |
2002 |
Antioxid. Redox Signal. |
pmid:12006176
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