Fu Y et al. |
Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12, 14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages. |
2002 |
Atherosclerosis |
pmid:11755918
|
Suzuki R and Freed AN |
Heparin inhibits hyperventilation-induced late-phase hyperreactivity in dogs. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:11779726
|
Shibata T et al. |
15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. |
2002 |
J. Biol. Chem. |
pmid:11786541
|
Simonin MA et al. |
PPAR-gamma ligands modulate effects of LPS in stimulated rat synovial fibroblasts. |
2002 |
Am. J. Physiol., Cell Physiol. |
pmid:11742805
|
Pestel S et al. |
Inhibition by prostaglandin E(2) of anaphylatoxin C5a- but not zymosan-induced prostanoid release from rat Kupffer cells. |
2002 |
Lab. Invest. |
pmid:11950903
|
Nishida K et al. |
Inhibition of human chondrosarcoma cell growth via apoptosis by peroxisome proliferator-activated receptor-gamma. |
2002 |
Br. J. Cancer |
pmid:11953889
|
Finck BN and Johnson RW |
Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:11959686
|
Bureau F et al. |
A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-kappa B inhibition. |
2002 |
J. Immunol. |
pmid:11994490
|
Kohyama T et al. |
Prostaglandin D2 inhibits fibroblast migration. |
2002 |
Eur. Respir. J. |
pmid:11998998
|
Sharif NA and Davis TL |
Cloned human EP1 prostanoid receptor pharmacology characterized using radioligand binding techniques. |
2002 |
J. Pharm. Pharmacol. |
pmid:11999132
|
Janabi N |
Selective inhibition of cyclooxygenase-2 expression by 15-deoxy-Delta(12,14)(12,14)-prostaglandin J(2) in activated human astrocytes, but not in human brain macrophages. |
2002 |
J. Immunol. |
pmid:11971025
|
Wayman NS et al. |
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. |
2002 |
FASEB J. |
pmid:12087064
|
Lennon AM et al. |
MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive oxygenated species. |
2002 |
J. Biol. Chem. |
pmid:12052825
|
Lappas M et al. |
Regulation of proinflammatory cytokines in human gestational tissues by peroxisome proliferator-activated receptor-gamma: effect of 15-deoxy-Delta(12,14)-PGJ(2) and troglitazone. |
2002 |
J. Clin. Endocrinol. Metab. |
pmid:12364456
|
Skolnik PR et al. |
Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. |
2002 |
J. Acquir. Immune Defic. Syndr. |
pmid:12352144
|
Eligini S et al. |
15-deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial cells: evidence for ERK1/2 signaling pathway blockade. |
2002 |
Thromb. Haemost. |
pmid:12353085
|
Suzuki K and Uyeda M |
Inhibitory properties of antitumor prostaglandins against topoisomerases. |
2002 |
Biosci. Biotechnol. Biochem. |
pmid:12353631
|
Campo PA et al. |
Translational regulation of cyclin D1 by 15-deoxy-delta(12,14)-prostaglandin J(2). |
2002 |
Cell Growth Differ. |
pmid:12354750
|
Shahbazian A et al. |
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine. |
2002 |
Br. J. Pharmacol. |
pmid:12429577
|
Hashimoto K et al. |
Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells. |
2002 |
Int J Gastrointest Cancer |
pmid:12630765
|
Tzanakakis GN et al. |
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. |
2002 |
Int J Gastrointest Cancer |
pmid:12630766
|
Nithipatikom K et al. |
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion. |
2002 |
Clin. Exp. Metastasis |
pmid:12498388
|
Takano H and Komuro I |
Roles of peroxisome proliferator-activated receptor gamma in cardiovascular disease. |
2002 Jan-Feb |
J. Diabetes Complicat. |
pmid:11872377
|
Bishop-Bailey D and Warner TD |
PPARgamma ligands induce prostaglandin production in vascular smooth muscle cells: indomethacin acts as a peroxisome proliferator-activated receptor-gamma antagonist. |
2003 |
FASEB J. |
pmid:12897060
|
Souza SC et al. |
TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes. |
2003 |
J. Cell. Biochem. |
pmid:12898507
|
Zhuang H et al. |
Prostaglandins of J series control heme oxygenase expression: potential significance in modulating neuroinflammation. |
2003 |
Ann. N. Y. Acad. Sci. |
pmid:12853315
|
Pestel S et al. |
Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. |
2003 |
Biochem. Pharmacol. |
pmid:12906929
|
Pritts EA et al. |
Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element. |
2003 |
Fertil. Steril. |
pmid:12909507
|
Zanoni G et al. |
A --> J prostaglandin swap: a new tactic for cyclopentenone prostaglandin synthesis. |
2003 |
J. Org. Chem. |
pmid:12919053
|
Nencioni A et al. |
Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling. |
2003 |
J. Immunol. |
pmid:14607914
|
Zhang M et al. |
[Apoptosis of human lung cancer cells induced by activated peroxisome proliferator-activated receptor-gamma and its mechanism]. |
2003 |
Zhonghua Yi Xue Za Zhi |
pmid:12921638
|
Honda K et al. |
Prostaglandin D2 reinforces Th2 type inflammatory responses of airways to low-dose antigen through bronchial expression of macrophage-derived chemokine. |
2003 |
J. Exp. Med. |
pmid:12925672
|
Mendez M and LaPointe MC |
PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes. |
2003 |
Hypertension |
pmid:12885795
|
Li L et al. |
Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts. |
2003 |
Gastroenterology |
pmid:12891549
|
Vosseler CA et al. |
Structural requirements of cyclopentenone prostaglandins to induce endothelial cell apoptosis. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12859958
|
Aoun P et al. |
Neuroprotective effects of PPARgamma agonists against oxidative insults in HT-22 cells. |
2003 |
Eur. J. Pharmacol. |
pmid:12860474
|
Zanoni G et al. |
First total synthesis of JS isoprostane. |
2003 |
J. Org. Chem. |
pmid:12868940
|
Zahradka P et al. |
Activation of peroxisome proliferator-activated receptors alpha and gamma1 inhibits human smooth muscle cell proliferation. |
2003 |
Mol. Cell. Biochem. |
pmid:12841350
|
Yang L et al. |
Peroxisome proliferator-activated receptor gamma and ligands inhibit surfactant protein B gene expression in the lung. |
2003 |
J. Biol. Chem. |
pmid:12829715
|
Date M et al. |
15-Deoxy-delta12,14-prostaglandin J2, a ligand for peroxisome proliferators-activated receptor-gamma, induces apoptosis in human hepatoma cells. |
2003 |
Liver Int. |
pmid:14986820
|
Houston KD et al. |
Inhibition of proliferation and estrogen receptor signaling by peroxisome proliferator-activated receptor gamma ligands in uterine leiomyoma. |
2003 |
Cancer Res. |
pmid:12649180
|
Kim BE et al. |
Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2. |
2003 |
Exp. Mol. Med. |
pmid:14508070
|
Piliponsky AM et al. |
Non-IgE-dependent activation of human lung- and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor. |
2003 |
Blood |
pmid:12393403
|
Yuan Z et al. |
Peroxisome proliferation-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis. |
2003 |
Cardiovasc. Res. |
pmid:14499870
|
Aoun P et al. |
Role of PPAR-gamma ligands in neuroprotection against glutamate-induced cytotoxicity in retinal ganglion cells. |
2003 |
Invest. Ophthalmol. Vis. Sci. |
pmid:12824244
|
Sugimoto H et al. |
An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12649388
|
Urade Y and Eguchi N |
[Sleep substances]. |
2003 |
No To Shinkei |
pmid:12649899
|
Smith SA et al. |
Effects of peroxisome proliferator-activated receptor gamma ligands ciglitazone and 15-deoxy-delta 12,14-prostaglandin J2 on rat cultured cerebellar granule neuronal viability. |
2003 |
J. Neurosci. Res. |
pmid:12774315
|
Zamuner SR et al. |
Cyclooxygenase 2 mediates post-inflammatory colonic secretory and barrier dysfunction. |
2003 |
Gut |
pmid:14633948
|
Armoni M et al. |
Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect. |
2003 |
J. Biol. Chem. |
pmid:12777391
|
Shibata T et al. |
An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome. |
2003 |
Biochemistry |
pmid:14636064
|
Liu H et al. |
PPARgamma ligands and ATRA inhibit the invasion of human breast cancer cells in vitro. |
2003 |
Breast Cancer Res. Treat. |
pmid:12779083
|
Villegas I et al. |
A new flavonoid derivative, dosmalfate, attenuates the development of dextran sulphate sodium-induced colitis in mice. |
2003 |
Int. Immunopharmacol. |
pmid:14636824
|
Mitsumori S et al. |
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 1. Bicyclo[2.2.1]heptane derivatives. |
2003 |
J. Med. Chem. |
pmid:12773047
|
Inoue K et al. |
Effect of 15-deoxy-delta 12,14-prostaglandin J2 on acute lung injury induced by lipopolysaccharide in mice. |
2003 |
Eur. J. Pharmacol. |
pmid:14642794
|
Mitsumori S et al. |
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane derivatives. |
2003 |
J. Med. Chem. |
pmid:12773048
|
Ide T et al. |
Activation of nuclear receptors by prostaglandins. |
2003 |
Thromb. Res. |
pmid:14592554
|
Kim EJ et al. |
Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12966153
|
Yagami T et al. |
Novel binding sites of 15-deoxy-Delta12,14-prostaglandin J2 in plasma membranes from primary rat cortical neurons. |
2003 |
Exp. Cell Res. |
pmid:14597421
|
Collin M and Thiemermann C |
The PPAR-gamma ligand 15-deoxy(delta12,14) prostaglandin J2 reduces the liver injury in endotoxic shock. |
2003 |
Eur. J. Pharmacol. |
pmid:12969773
|
Cuzzocrea S et al. |
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. |
2003 |
Br. J. Pharmacol. |
pmid:12970094
|
Caivano M et al. |
15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide. |
2003 |
J. Biol. Chem. |
pmid:14557273
|
Farrow B et al. |
Selective activation of PPARgamma inhibits pancreatic cancer invasion and decreases expression of tissue plasminogen activator. |
2003 |
Surgery |
pmid:12947319
|
Murakami Y et al. |
Inhibition of monosodium urate monohydrate crystal-induced acute inflammation by retrovirally transfected prostaglandin D synthase. |
2003 |
Arthritis Rheum. |
pmid:14558100
|
Zhang M et al. |
Peroxisome proliferator-activated receptor-gamma activated by ligands can inhibit human lung cancer cell growth through induction of apoptosis. |
2003 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:12973930
|
Niyonsaba F et al. |
Epithelial cell-derived antibacterial peptides human beta-defensins and cathelicidin: multifunctional activities on mast cells. |
2003 |
Curr Drug Targets Inflamm Allergy |
pmid:14561157
|
Powell WS |
15-Deoxy-delta12,14-PGJ2: endogenous PPARgamma ligand or minor eicosanoid degradation product? |
2003 |
J. Clin. Invest. |
pmid:12975467
|
Chen YX et al. |
15d-PGJ2 inhibits cell growth and induces apoptosis of MCG-803 human gastric cancer cell line. |
2003 |
World J. Gastroenterol. |
pmid:14562367
|
Bell-Parikh LC et al. |
Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma. |
2003 |
J. Clin. Invest. |
pmid:12975479
|
Shichijo M et al. |
Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced eosinophilia in rats. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12975488
|
Gilroy DW et al. |
Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis. |
2003 |
FASEB J. |
pmid:14563690
|
Pierzchalska M et al. |
Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. |
2003 |
J. Allergy Clin. Immunol. |
pmid:12743569
|
Okano H et al. |
15-deoxy-delta-12-14-PGJ2 regulates apoptosis induction and nuclear factor-kappaB activation via a peroxisome proliferator-activated receptor-gamma-independent mechanism in hepatocellular carcinoma. |
2003 |
Lab. Invest. |
pmid:14563954
|
Jowsey IR et al. |
Expression of the murine glutathione S-transferase alpha3 (GSTA3) subunit is markedly induced during adipocyte differentiation: activation of the GSTA3 gene promoter by the pro-adipogenic eicosanoid 15-deoxy-Delta12,14-prostaglandin J2. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14652005
|
Hammad H et al. |
Prostaglandin D2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1. |
2003 |
J. Immunol. |
pmid:14530310
|
Takata K et al. |
Possible involvement of small oligomers of amyloid-beta peptides in 15-deoxy-delta 12,14 prostaglandin J2-sensitive microglial activation. |
2003 |
J. Pharmacol. Sci. |
pmid:12719662
|
Liu JD et al. |
Involvement of c-jun N-terminal kinase activation in 15-deoxy-delta12,14-prostaglandin J2-and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells. |
2003 |
Mol. Carcinog. |
pmid:12720296
|
Hata AN et al. |
Expression and molecular pharmacology of the mouse CRTH2 receptor. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12721327
|
Yee LD et al. |
The antiproliferative effects of PPARgamma ligands in normal human mammary epithelial cells. |
2003 |
Breast Cancer Res. Treat. |
pmid:12725418
|
Oliva JL et al. |
The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12684535
|
Paumi CM et al. |
Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. |
2003 |
Biochemistry |
pmid:12731885
|
Gosset P et al. |
Prostaglandin D2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. |
2003 |
J. Immunol. |
pmid:12734337
|
Lu S et al. |
Specific gene expression of isoforms in cyclooxygenase pathway to generate PGJ2 derivatives during the differentiation of 3T3-L1 adipocytes. |
2003 |
Adv. Exp. Med. Biol. |
pmid:12751756
|
Imaizumi T et al. |
15-deoxy-delta(12,14)-prostaglandin J2 inhibits IFN-gamma-induced galectin-9 expression in cultured human umbilical vein endothelial cells. |
2003 |
Int. Arch. Allergy Immunol. |
pmid:12759491
|
Sommer A et al. |
A dominant role for extracellular glutathione S-transferase from Onchocerca volvulus is the production of prostaglandin D2. |
2003 |
Infect. Immun. |
pmid:12761146
|
Irikura D et al. |
Cloning, expression, crystallization, and preliminary X-ray analysis of recombinant mouse lipocalin-type prostaglandin D synthase, a somnogen-producing enzyme. |
2003 |
J. Biochem. |
pmid:12761195
|
Shibata T et al. |
Thioredoxin as a molecular target of cyclopentenone prostaglandins. |
2003 |
J. Biol. Chem. |
pmid:12709421
|
Zhuang H et al. |
Regulation of heme oxygenase expression by cyclopentenone prostaglandins. |
2003 |
Exp. Biol. Med. (Maywood) |
pmid:12709576
|
Kämpfer H et al. |
Cyclooxygenase-1-coupled prostaglandin biosynthesis constitutes an essential prerequisite for skin repair. |
2003 |
J. Invest. Dermatol. |
pmid:12713596
|
Brown JR et al. |
Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD). |
2003 |
J. Leukoc. Biol. |
pmid:12714573
|
Abe M et al. |
GATA-6 is involved in PPARgamma-mediated activation of differentiated phenotype in human vascular smooth muscle cells. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12615657
|
Qin C et al. |
Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. |
2003 |
Cancer Res. |
pmid:12615709
|
Kajekar R et al. |
Role of cyclooxygenase activation and prostaglandins in antigen-induced excitability changes of bronchial parasympathetic ganglia neurons. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12618420
|
Wanichkul T et al. |
Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells. |
2003 |
Fertil. Steril. |
pmid:12620489
|
Monneret G et al. |
15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12490611
|
Li L et al. |
RasGRP4 regulates the expression of prostaglandin D2 in human and rat mast cell lines. |
2003 |
J. Biol. Chem. |
pmid:12493770
|
Winnett G et al. |
Prostaglandin J2 metabolites inhibit aromatase activity by redox-sensitive mechanisms: potential implications for breast cancer therapy. |
2003 |
Int. J. Cancer |
pmid:12494466
|
Kalla R et al. |
Loss of microglial ramification in microglia-astrocyte cocultures: involvement of adenylate cyclase, calcium, phosphatase, and Gi-protein systems. |
2003 |
Glia |
pmid:12465045
|
Arici M et al. |
Stimulation of proximal tubular cell apoptosis by albumin-bound fatty acids mediated by peroxisome proliferator activated receptor-gamma. |
2003 |
J. Am. Soc. Nephrol. |
pmid:12506134
|
Hirano A et al. |
Arachidonic acid-induced channel- and carrier-type ion transport across planar bilayer lipid membranes. |
2003 |
Anal Sci |
pmid:12608744
|