Matsuo T et al. |
15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-kappaB. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:14741709
|
Józkowicz A et al. |
Opposite effects of prostaglandin-J2 on VEGF in normoxia and hypoxia: role of HIF-1. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:14715242
|
Odani N et al. |
Induction of protein disulfide isomerase mRNA by delta 12-prostaglandin J2. |
1996 |
Biochem. Biophys. Res. Commun. |
pmid:8645293
|
Matsumoto H et al. |
Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat peritoneal macrophages. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9020023
|
Soares AF et al. |
Covalent binding of 15-deoxy-delta12,14-prostaglandin J2 to PPARgamma. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:16198309
|
Asami-Miyagishi R et al. |
Expression and function of PPARgamma in rat placental development. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:14766236
|
Wong GW et al. |
Ancient origin of mast cells. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:25094046
|
Satoh H et al. |
Thiazolidinediones suppress endothelin-1 secretion from bovine vascular endothelial cells: a new possible role of PPARgamma on vascular endothelial function. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:9920814
|
Ohtani-Fujita N et al. |
p53-Independent activation of the gadd45 promoter by Delta12-prostaglandin J2. |
1998 |
Biochem. Biophys. Res. Commun. |
pmid:9792828
|
Narumiya S and Fukushima M |
delta 12-Prostaglandin J2, an ultimate metabolite of prostaglandin D2 exerting cell growth inhibition. |
1985 |
Biochem. Biophys. Res. Commun. |
pmid:3857041
|
Iijima K et al. |
Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in rat aortic smooth muscle cells. |
1998 |
Biochem. Biophys. Res. Commun. |
pmid:9642130
|
Baregamian N et al. |
PPAR-gamma agonist protects against intestinal injury during necrotizing enterocolitis. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19114032
|
Pelton PD et al. |
PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes. |
1999 |
Biochem. Biophys. Res. Commun. |
pmid:10425206
|
Ichiki T et al. |
15-Deoxy-Delta12,14-prostaglandin J2 and thiazolidinediones transactivate epidermal growth factor and platelet-derived growth factor receptors in vascular smooth muscle cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15369766
|
Kuesap J et al. |
Prostaglandin D2 induces heme oxygenase-1 in human retinal pigment epithelial cells. |
2008 |
Biochem. Biophys. Res. Commun. |
pmid:18174022
|
Miwa Y et al. |
Involvement of clusterin in 15-deoxy-delta12,14-prostaglandin J2-induced vascular smooth muscle cell differentiation. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15158456
|
Andersen NH and Hartzell CJ |
High-field 1H NMR studies of prostaglandin H2 and its decomposition pathways. |
1984 |
Biochem. Biophys. Res. Commun. |
pmid:6587849
|
Kinoshita T et al. |
Predominance of prostaglandin D2 and I2 in the rat gastric mucosa--analysis by high-performance liquid chromatography. |
1987 |
Biochem. Int. |
pmid:3555501
|
Diers AR et al. |
Modulation of mammary cancer cell migration by 15-deoxy-delta(12,14)-prostaglandin J(2): implications for anti-metastatic therapy. |
2010 |
Biochem. J. |
pmid:20536428
|
Sanchez-Rodriguez J et al. |
The spot 14 protein inhibits growth and induces differentiation and cell death of human MCF-7 breast cancer cells. |
2005 |
Biochem. J. |
pmid:15819613
|
GarcÃa-Sáinz JA et al. |
Melittin stimulates liver glycogenolysis and the release of prostaglandin D2 and thromboxane B2. |
1990 |
Biochem. J. |
pmid:2375756
|
vom Dahl S et al. |
Stimulation of release of prostaglandin D2 and thromboxane B2 from perfused rat liver by extracellular adenosine. |
1990 |
Biochem. J. |
pmid:2396991
|
Rodway HA et al. |
Lysophosphatidic acid attenuates the cytotoxic effects and degree of peroxisome proliferator-activated receptor gamma activation induced by 15-deoxyDelta12,14-prostaglandin J2 in neuroblastoma cells. |
2004 |
Biochem. J. |
pmid:15171682
|
Altin JG and Bygrave FL |
Prostaglandin F2 alpha and the thromboxane A2 analogue ONO-11113 stimulate Ca2+ fluxes and other physiological responses in rat liver. Further evidence that prostanoids may be involved in the action of arachidonic acid and platelet-activating factor. |
1988 |
Biochem. J. |
pmid:3128268
|
Smith JB et al. |
Cyclic AMP does not inhibit collagen-induced platelet signal transduction. |
1992 |
Biochem. J. |
pmid:1375452
|
Ashraf M et al. |
Cross-linking of the high-affinity IgE receptor induces the expression of cyclo-oxygenase 2 and attendant prostaglandin generation requiring interleukin 10 and interleukin 1 beta in mouse cultured mast cells. |
1996 |
Biochem. J. |
pmid:9003387
|
Landar A et al. |
Induction of the permeability transition and cytochrome c release by 15-deoxy-Delta12,14-prostaglandin J2 in mitochondria. |
2006 |
Biochem. J. |
pmid:16268779
|
Shiraki T et al. |
Spectroscopic analyses of the binding kinetics of 15d-PGJ2 to the PPARgamma ligand-binding domain by multi-wavelength global fitting. |
2006 |
Biochem. J. |
pmid:16236024
|
Ricart KC et al. |
The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. |
2009 |
Biochem. J. |
pmid:19161347
|
Casteleijn E et al. |
Prostaglandin D2 mediates the stimulation of glycogenolysis in the liver by phorbol ester. |
1988 |
Biochem. J. |
pmid:3162673
|
Williams KA et al. |
Effects of activation of protein kinase C on the agonist-induced stimulation and inhibition of cyclic AMP formation in intact human platelets. |
1987 |
Biochem. J. |
pmid:2444206
|
Casteleijn E et al. |
Conditioned media of Kupffer and endothelial liver cells influence protein phosphorylation in parenchymal liver cells. Involvement of prostaglandins. |
1988 |
Biochem. J. |
pmid:3166374
|
Thomson AM et al. |
Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class Sigma glutathione S-transferase. |
1998 |
Biochem. J. |
pmid:9657971
|
Takahashi S et al. |
Localization of a cyclopentenone prostaglandin to the endoplasmic reticulum and induction of BiP mRNA. |
1998 |
Biochem. J. |
pmid:9742210
|
Levonen AL et al. |
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. |
2004 |
Biochem. J. |
pmid:14616092
|
Brass EP and Garrity MJ |
Structural specificity for prostaglandin effects on hepatocyte glycogenolysis. |
1990 |
Biochem. J. |
pmid:2158311
|
Oh JY et al. |
Accumulation of 15-deoxy-delta(12,14)-prostaglandin J2 adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction. |
2008 |
Biochem. J. |
pmid:18237271
|
Bushfield M et al. |
Inhibition of platelet-activating-factor-induced human platelet activation by prostaglandin D2. Differential sensitivity of platelet transduction processes and functional responses to inhibition by cyclic AMP. |
1985 |
Biochem. J. |
pmid:3002327
|
Diers AR et al. |
Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. |
2010 |
Biochem. J. |
pmid:19916962
|
Neuschäfer-Rube F et al. |
Identification by site-directed mutagenesis of amino acids contributing to ligand-binding specificity or signal transduction properties of the human FP prostanoid receptor. |
2003 |
Biochem. J. |
pmid:12519077
|
Kuiper J et al. |
Cellular communication inside the liver. Binding, conversion and metabolic effect of prostaglandin D2 on parenchymal liver cells. |
1989 |
Biochem. J. |
pmid:2818563
|
Pandey HP et al. |
Concentration of prostaglandin D2 in cerebrospinal fluid exhibits a circadian alteration in conscious rats. |
1995 |
Biochem. Mol. Biol. Int. |
pmid:8595382
|
Fowler CJ and Tiger G |
Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro. |
2005 |
Biochem. Pharmacol. |
pmid:15794945
|
Jacobsen S et al. |
Synergism between thapsigargin and the phorbol ester 12-O-tetradecanoylphorbol 13-acetate on the release of [14C]arachidonic acid and histamine from rat peritoneal mast cells. |
1987 |
Biochem. Pharmacol. |
pmid:2435291
|
Fernández-Tome M et al. |
COX-2-mediated PGD2 synthesis regulates phosphatidylcholine biosynthesis in rat renal papillary tissue. |
2004 |
Biochem. Pharmacol. |
pmid:14698037
|
Pestel S et al. |
Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. |
2003 |
Biochem. Pharmacol. |
pmid:12906929
|
Koyani CN et al. |
Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death. |
2016 |
Biochem. Pharmacol. |
pmid:26801686
|
Ko FN et al. |
Inhibition of collagen-induced platelet aggregation and adhesion by a pseudocyanide derivative of avicine isolated from Zanthoxylum integrifoliolum Merr. |
1993 |
Biochem. Pharmacol. |
pmid:8216367
|
Gresele P et al. |
Serum albumin enhances the impairment of platelet aggregation with thromboxane synthase inhibition by increasing the formation of prostaglandin D2. |
1984 |
Biochem. Pharmacol. |
pmid:6430299
|
Cossette C et al. |
Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes. |
2015 |
Biochem. Pharmacol. |
pmid:26032638
|
Emi M and Maeyama K |
The biphasic effects of cyclopentenone prostaglandins, prostaglandin J(2) and 15-deoxy-Delta(12,14)-prostaglandin J(2) on proliferation and apoptosis in rat basophilic leukemia (RBL-2H3) cells. |
2004 |
Biochem. Pharmacol. |
pmid:15013841
|
Chbicheb S et al. |
EGR1 expression: a calcium and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12,14-prostaglandin J2 and thiazolidinediones in breast cancer cells. |
2011 |
Biochem. Pharmacol. |
pmid:21338579
|
Yu SM et al. |
Dicentrine, a novel antiplatelet agent inhibiting thromboxane formation and increasing the cyclic AMP level of rabbit platelets. |
1992 |
Biochem. Pharmacol. |
pmid:1310852
|
Ikai K et al. |
Inhibitory effect of tranilast on prostaglandin D synthetase. |
1989 |
Biochem. Pharmacol. |
pmid:2475113
|
MacDermot J |
Desensitization of prostacyclin responsiveness in platelets. Apparent differences in the mechanism in vitro or in vivo. |
1986 |
Biochem. Pharmacol. |
pmid:2427086
|
Yamamoto S et al. |
Agents that elevate cyclic AMP induce receptor phosphorylation primarily at serine 331 in HEK 293 cells overexpressing human thromboxane receptor alpha. |
2002 |
Biochem. Pharmacol. |
pmid:12147288
|
Surh YJ et al. |
15-Deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚, an electrophilic lipid mediator of anti-inflammatory and pro-resolving signaling. |
2011 |
Biochem. Pharmacol. |
pmid:21843512
|
Lu Y et al. |
Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation. |
2011 |
Biochem. Pharmacol. |
pmid:21907188
|
Liu C et al. |
15d-PGJâ‚‚ decreases PGEâ‚‚ synthesis in HBx-positive liver cells by interfering EGR1 binding to mPGES-1 promoter. |
2014 |
Biochem. Pharmacol. |
pmid:25108236
|
Tao H and Hajri T |
Very low density lipoprotein receptor promotes adipocyte differentiation and mediates the proadipogenic effect of peroxisome proliferator-activated receptor gamma agonists. |
2011 |
Biochem. Pharmacol. |
pmid:21924248
|
Faili A et al. |
Reduction by arachidonic acid of prostaglandin I2-induced cyclic AMP formation. Involvement of prostaglandins E2 and F2 alpha. |
1993 |
Biochem. Pharmacol. |
pmid:8388209
|
Koizumi T et al. |
Inhibitory effect of an intracellular glutathione on delta 12-prostaglandin J2-induced protein syntheses in porcine aortic endothelial cells. |
1992 |
Biochem. Pharmacol. |
pmid:1417983
|
Endo S et al. |
Rabbit 3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin Dâ‚‚, and other endogenous and xenobiotic carbonyl compounds. |
2013 |
Biochem. Pharmacol. |
pmid:23994167
|
Xue L et al. |
Inhibition of PI3K and calcineurin suppresses chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)-dependent responses of Th2 lymphocytes to prostaglandin D(2). |
2007 |
Biochem. Pharmacol. |
pmid:17196174
|
Quraishi O et al. |
Inhibition of inducible prostaglandin E(2) synthase by 15-deoxy-Delta(12,14)-prostaglandin J(2) and polyunsaturated fatty acids. |
2002 |
Biochem. Pharmacol. |
pmid:11931852
|
Casali CI et al. |
Coordinate regulation between the nuclear receptor peroxisome proliferator-activated receptor-γ and cyclooxygenase-2 in renal epithelial cells. |
2014 |
Biochem. Pharmacol. |
pmid:24915420
|
Woodward DF and Lawrence RA |
Identification of a single (FP) receptor associated with prostanoid-induced Ca2+ signals in Swiss 3T3 cells. |
1994 |
Biochem. Pharmacol. |
pmid:8185669
|
Robinson C et al. |
The metabolism of prostaglandin D2. Evidence for the sequential conversion by NADPH and NAD+ dependent pathways. |
1989 |
Biochem. Pharmacol. |
pmid:2818626
|
Koizumi T et al. |
Activation of heat shock transcription factors by delta 12-prostaglandin J2 and its inhibition by intracellular glutathione. |
1993 |
Biochem. Pharmacol. |
pmid:8328983
|
Hoult JR et al. |
Organ selective conversion of prostaglandin D2 to 9 alpha, 11 beta-prostaglandin F2 and its subsequent metabolism in rat, rabbit and guinea pig. |
1988 |
Biochem. Pharmacol. |
pmid:3178873
|
Schuligoi R et al. |
PGD2 metabolism in plasma: kinetics and relationship with bioactivity on DP1 and CRTH2 receptors. |
2007 |
Biochem. Pharmacol. |
pmid:17452035
|
Kim EH and Surh YJ |
The role of 15-deoxy-delta(12,14)-prostaglandin J(2), an endogenous ligand of peroxisome proliferator-activated receptor gamma, in tumor angiogenesis. |
2008 |
Biochem. Pharmacol. |
pmid:18771658
|
Kim JW et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) rescues PC12 cells from H2O2-induced apoptosis through Nrf2-mediated upregulation of heme oxygenase-1: potential roles of Akt and ERK1/2. |
2008 |
Biochem. Pharmacol. |
pmid:18775681
|
Gebicke-Haerter PJ et al. |
Pertussis and cholera toxins inhibit prostaglandin synthesis in rat astrocyte cultures at distinct metabolic steps. |
1991 |
Biochem. Pharmacol. |
pmid:1909527
|
Cocca C et al. |
15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest. |
2009 |
Biochem. Pharmacol. |
pmid:19576185
|
Rajtar G et al. |
Prostaglandins and human platelet aggregation. Implications for the anti-aggregating activity of thromboxane-synthase inhibitors. |
1985 |
Biochem. Pharmacol. |
pmid:3918536
|
Richelsen B |
Relationship between binding and action of different prostaglandins in rat adipocytes with special reference to PGE2 and PGI2. |
1987 |
Biochem. Pharmacol. |
pmid:2825710
|
Koizumi T et al. |
Induction of a 31,000-dalton stress protein by prostaglandins D2 and J2 in porcine aortic endothelial cells. |
1991 |
Biochem. Pharmacol. |
pmid:1867634
|
Coyle AT and Kinsella BT |
Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells. |
2006 |
Biochem. Pharmacol. |
pmid:16499875
|
Kanda N et al. |
Prostaglandin D2 induces the production of human beta-defensin-3 in human keratinocytes. |
2010 |
Biochem. Pharmacol. |
pmid:19925780
|
Crivellari MT et al. |
Eicosanoid release and mepyramine, LTC4 and LTD4 binding in passively sensitized human lung parenchyma in vitro. |
1991 |
Biochem. Pharmacol. |
pmid:1859453
|
Liu JY et al. |
Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model. |
2010 |
Biochem. Pharmacol. |
pmid:19896470
|
Kim EH and Surh YJ |
15-deoxy-Delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors. |
2006 |
Biochem. Pharmacol. |
pmid:16987499
|
Harbige LS et al. |
Cytokine secretion by human T cell clones is differentially regulated by eicosanoids. |
1997 |
Biochem. Soc. Trans. |
pmid:9191392
|
Emmans VC et al. |
Regulation of cellular processes by PPARgamma ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression. |
2004 |
Biochem. Soc. Trans. |
pmid:15494029
|
Ward C et al. |
Regulation of granulocyte apoptosis by NF-kappaB. |
2004 |
Biochem. Soc. Trans. |
pmid:15157161
|
Atsmon J et al. |
Formation of thiol conjugates of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 and delta 12(E)-prostaglandin D2. |
1990 |
Biochemistry |
pmid:2340271
|
Lin Q et al. |
Ligand selectivity of the peroxisome proliferator-activated receptor alpha. |
1999 |
Biochemistry |
pmid:9890897
|
Paumi CM et al. |
Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2). |
2004 |
Biochemistry |
pmid:14979731
|
Boutaud O et al. |
Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid. |
2001 |
Biochemistry |
pmid:11389610
|
Li H et al. |
Serum amyloid A activates peroxisome proliferator-activated receptor γ through extracellularly regulated kinase 1/2 and COX-2 expression in hepatocytes. |
2010 |
Biochemistry |
pmid:20853849
|
Aldini G et al. |
Identification of actin as a 15-deoxy-Delta12,14-prostaglandin J2 target in neuroblastoma cells: mass spectrometric, computational, and functional approaches to investigate the effect on cytoskeletal derangement. |
2007 |
Biochemistry |
pmid:17297918
|
Carrier EJ et al. |
Levuglandin forms adducts with histone h4 in a cyclooxygenase-2-dependent manner, altering its interaction with DNA. |
2014 |
Biochemistry |
pmid:24684440
|
Renedo M et al. |
Modification and activation of Ras proteins by electrophilic prostanoids with different structure are site-selective. |
2007 |
Biochemistry |
pmid:17489560
|
Shibata T et al. |
An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome. |
2003 |
Biochemistry |
pmid:14636064
|
Paumi CM et al. |
Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. |
2003 |
Biochemistry |
pmid:12731885
|
Reich EE et al. |
Formation of novel D-ring and E-ring isoprostane-like compounds (D4/E4-neuroprostanes) in vivo from docosahexaenoic acid. |
2000 |
Biochemistry |
pmid:10694406
|
Prage EB et al. |
Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2). |
2012 |
Biochemistry |
pmid:22356188
|
Penas F et al. |
Treatment in vitro with PPARα and PPARγ ligands drives M1-to-M2 polarization of macrophages from T. cruzi-infected mice. |
2015 |
Biochim. Biophys. Acta |
pmid:25557389
|
Urade Y and Hayaishi O |
Prostaglandin D2 and sleep regulation. |
1999 |
Biochim. Biophys. Acta |
pmid:9989291
|