Sanchez-Rodriguez J et al. |
The spot 14 protein inhibits growth and induces differentiation and cell death of human MCF-7 breast cancer cells. |
2005 |
Biochem. J. |
pmid:15819613
|
Kim YS et al. |
Distinct protective mechanisms of HO-1 and HO-2 against hydroperoxide-induced cytotoxicity. |
2005 |
Free Radic. Biol. Med. |
pmid:15589375
|
Almishri W et al. |
Effects of prostaglandin D2, 15-deoxy-Delta12,14-prostaglandin J2, and selective DP1 and DP2 receptor agonists on pulmonary infiltration of eosinophils in Brown Norway rats. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15590767
|
Soares AF et al. |
Covalent binding of 15-deoxy-delta12,14-prostaglandin J2 to PPARgamma. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:16198309
|
Xue L et al. |
Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells. |
2005 |
J. Immunol. |
pmid:16272307
|
Yuhas Y et al. |
Involvement of prostaglandins in an animal model of Shigella-related seizures. |
2005 |
J. Neuroimmunol. |
pmid:16139898
|
Gayarre J et al. |
Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Delta12,14-PGJ2: role of glutathione. |
2005 |
FEBS Lett. |
pmid:16223487
|
Hatoum OA et al. |
Novel mechanism of vasodilation in inflammatory bowel disease. |
2005 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:16141408
|
Muñoz U et al. |
The cyclopentenone 15-deoxy-delta(12,14)-prostaglandin J2 inhibits G1/S transition and retinoblastoma protein phosphorylation in immortalized lymphocytes from Alzheimer's disease patients. |
2005 |
Exp. Neurol. |
pmid:16061222
|
Chen ZY and Tseng CC |
15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal transduction pathway in HT-29 colon cancer cells. |
2005 |
Mol. Pharmacol. |
pmid:16077033
|
Chevalier E et al. |
Cutting edge: chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment. |
2005 |
J. Immunol. |
pmid:16081770
|
Jerde TJ et al. |
Celecoxib inhibits ureteral contractility and prostanoid release. |
2005 |
Urology |
pmid:15667901
|
Figarella K et al. |
Prostaglandin D2 induces programmed cell death in Trypanosoma brucei bloodstream form. |
2005 |
Cell Death Differ. |
pmid:15678148
|
Capobianco E et al. |
15-Deoxy-Delta12,14-prostaglandin J2 and peroxisome proliferator-activated receptor gamma (PPARgamma) levels in term placental tissues from control and diabetic rats: modulatory effects of a PPARgamma agonist on nitridergic and lipid placental metabolism. |
2005 |
Reprod. Fertil. Dev. |
pmid:15899154
|
Avis I et al. |
Inhibitors of the arachidonic acid pathway and peroxisome proliferator-activated receptor ligands have superadditive effects on lung cancer growth inhibition. |
2005 |
Cancer Res. |
pmid:15899809
|
Lappas M et al. |
Effect of nuclear factor-kappa B inhibitors and peroxisome proliferator-activated receptor-gamma ligands on PTHrP release from human fetal membranes. |
2004 Sep-Oct |
Placenta |
pmid:15450387
|
Dong YG et al. |
Effects of 15-deoxy-delta12,14-prostaglandin J2 on cell proliferation and apoptosis in ECV304 endothelial cells. |
2004 |
Acta Pharmacol. Sin. |
pmid:14704122
|
|
PPAR activators and gastroenterology. |
2004 |
Drug News Perspect. |
pmid:15801147
|
Kumar AP et al. |
Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism. |
2004 |
J. Biol. Chem. |
pmid:14668325
|
Böhm E et al. |
11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. |
2004 |
J. Biol. Chem. |
pmid:14668348
|
Itoh K et al. |
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2). |
2004 |
Mol. Cell. Biol. |
pmid:14673141
|
Abdelrahman M et al. |
The peroxisome proliferator-activated receptor-gamma ligand 15-deoxyDelta12,14 prostaglandin J2 reduces the organ injury in hemorrhagic shock. |
2004 |
Shock |
pmid:15545828
|
Chen F |
Endogenous inhibitors of nuclear factor-kappaB, an opportunity for cancer control. |
2004 |
Cancer Res. |
pmid:15548674
|
Inoue K et al. |
Effects of 15-deoxy-delta12,14-prostaglandin J2 on the cyclooxygenase-2 expression in the murine lung in the presence of lipopolysaccharide. |
2004 |
Arzneimittelforschung |
pmid:15612612
|
Mitsumori S |
Recent progress in work on PGD2 antagonists for drugs targeting allergic diseases. |
2004 |
Curr. Pharm. Des. |
pmid:15579050
|
Arai I et al. |
Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis. |
2004 |
Eur. J. Pharmacol. |
pmid:15556157
|
Chen Q et al. |
A yeast two-hybrid technology-based system for the discovery of PPARgamma agonist and antagonist. |
2004 |
Anal. Biochem. |
pmid:15556564
|
Kim BE et al. |
Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by Delta12-prostaglandin J2. |
2004 |
Exp. Mol. Med. |
pmid:15557816
|
Józkowicz A et al. |
15-deoxy-delta12,14-prostaglandin-J2 inhibits expression of eNOS in human endothelial cells. |
2004 |
Prostaglandins Other Lipid Mediat. |
pmid:15560113
|
Diab A et al. |
Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis. |
2004 |
J. Neuroimmunol. |
pmid:14975592
|
Paumi CM et al. |
Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2). |
2004 |
Biochemistry |
pmid:14979731
|
Fogel-Petrovic M et al. |
Activated human dendritic cells express inducible cyclo-oxygenase and synthesize prostaglandin E2 but not prostaglandin D2. |
2004 |
Immunol. Cell Biol. |
pmid:14984594
|
Cheng S et al. |
Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. |
2004 |
J. Biol. Chem. |
pmid:15023995
|
Alvarez-Maqueda M et al. |
15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes. |
2004 |
J. Biol. Chem. |
pmid:15024026
|
Marone G et al. |
The human heart as a shock organ in anaphylaxis. |
2004 |
Novartis Found. Symp. |
pmid:15025396
|
Qin C et al. |
A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes. |
2004 |
Mol. Cancer Ther. |
pmid:15026545
|
Hashimoto K et al. |
Activation and role of MAP kinases in 15d-PGJ2-induced apoptosis in the human pancreatic cancer cell line MIA PaCa-2. |
2004 |
Pancreas |
pmid:15028947
|
Toyomoto M et al. |
Prostaglandins are powerful inducers of NGF and BDNF production in mouse astrocyte cultures. |
2004 |
FEBS Lett. |
pmid:15044028
|
Tanaka K et al. |
Effects of prostaglandin D2 on helper T cell functions. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15044085
|
Onozaki A et al. |
Rapid change of glucose concentration promotes mesangial cell proliferation via VEGF: inhibitory effects of thiazolidinedione. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15047143
|
Koda N et al. |
Synthesis of prostaglandin F ethanolamide by prostaglandin F synthase and identification of Bimatoprost as a potent inhibitor of the enzyme: new enzyme assay method using LC/ESI/MS. |
2004 |
Arch. Biochem. Biophys. |
pmid:15047184
|
Saydam O et al. |
Transactivator protein BICP0 of bovine herpesvirus 1 (BHV-1) is blocked by prostaglandin D2 (PGD2), which points to a mechanism for PGD2-mediated inhibition of BHV-1 replication. |
2004 |
J. Virol. |
pmid:15047795
|
Woolhiser MR et al. |
Activation of human mast cells by aggregated IgG through FcgammaRI: additive effects of C3a. |
2004 |
Clin. Immunol. |
pmid:15003814
|
Relic B et al. |
15-deoxy-delta12,14-prostaglandin J2 inhibits Bay 11-7085-induced sustained extracellular signal-regulated kinase phosphorylation and apoptosis in human articular chondrocytes and synovial fibroblasts. |
2004 |
J. Biol. Chem. |
pmid:15004016
|
Angeli V et al. |
Activation of the D prostanoid receptor 1 regulates immune and skin allergic responses. |
2004 |
J. Immunol. |
pmid:15004188
|
Lupi R et al. |
Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion. |
2004 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:14625208
|
Tsuji T et al. |
Differential effects of beta2-adrenoceptor desensitization on the IgE-dependent release of chemical mediators from cultured human mast cells. |
2004 |
Biol. Pharm. Bull. |
pmid:15467193
|
Konopleva M et al. |
Peroxisome proliferator-activated receptor gamma and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias. |
2004 |
Mol. Cancer Ther. |
pmid:15486192
|
Ishii T and Uchida K |
Induction of reversible cysteine-targeted protein oxidation by an endogenous electrophile 15-deoxy-delta12,14-prostaglandin J2. |
2004 |
Chem. Res. Toxicol. |
pmid:15487891
|
Li Z et al. |
Neurotoxic prostaglandin J2 enhances cyclooxygenase-2 expression in neuronal cells through the p38MAPK pathway: a death wish? |
2004 |
J. Neurosci. Res. |
pmid:15523637
|
Liu JD et al. |
Thiol antioxidant and thiol-reducing agents attenuate 15-deoxy-delta 12,14-prostaglandin J2-induced heme oxygenase-1 expression. |
2004 |
Life Sci. |
pmid:14998722
|
Sabichi AL et al. |
Peroxisome proliferator-activated receptor-gamma suppresses cyclooxygenase-2 expression in human prostate cells. |
2004 |
Cancer Epidemiol. Biomarkers Prev. |
pmid:15533896
|
Subbarayan V et al. |
Differential peroxisome proliferator-activated receptor-gamma isoform expression and agonist effects in normal and malignant prostate cells. |
2004 |
Cancer Epidemiol. Biomarkers Prev. |
pmid:15533897
|
Mix KS et al. |
Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling. |
2004 |
Mol. Pharmacol. |
pmid:14742672
|
Yuan Z et al. |
Peroxisome proliferator-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis associated with inhibition of self-sensitive T cells. |
2004 |
J. Cardiovasc. Pharmacol. |
pmid:15167281
|
Dahlén SE and Kumlin M |
Monitoring mast cell activation by prostaglandin D2 in vivo. |
2004 |
Thorax |
pmid:15170020
|
Bochenek G et al. |
Plasma 9alpha,11beta-PGF2, a PGD2 metabolite, as a sensitive marker of mast cell activation by allergen in bronchial asthma. |
2004 |
Thorax |
pmid:15170023
|
Cheron A et al. |
15-deoxy-Delta12,14-prostaglandin J2 inhibits glucocorticoid binding and signaling in macrophages through a peroxisome proliferator-activated receptor gamma-independent process. |
2004 |
J. Immunol. |
pmid:15187150
|
Maddox JF et al. |
15-deoxy prostaglandin J2 enhances allyl alcohol-induced toxicity in rat hepatocytes. |
2004 |
Toxicol. Sci. |
pmid:14657518
|
Baek SJ et al. |
Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. |
2004 |
J. Biol. Chem. |
pmid:14662774
|
Zhang X et al. |
Stress protein activation by the cyclopentenone prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in human mesangial cells. |
2004 |
Kidney Int. |
pmid:14871400
|
Ueta M et al. |
PPARgamma ligands attenuate mesangial contractile dysfunction in high glucose. |
2004 |
Kidney Int. |
pmid:14871416
|
Badawi AF et al. |
Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma. |
2004 |
Cancer Res. |
pmid:14871855
|
Levonen AL et al. |
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. |
2004 |
Biochem. J. |
pmid:14616092
|
Reddy RC et al. |
Deactivation of murine alveolar macrophages by peroxisome proliferator-activated receptor-gamma ligands. |
2004 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:14617516
|
Reddy PS et al. |
The synthesis and effects of prostaglandins on the ovary of the crab Oziotelphusa senex senex. |
2004 |
Gen. Comp. Endocrinol. |
pmid:14644642
|
Ehara N et al. |
Activators of PPARgamma antagonize protection of cardiac myocytes by endothelin-1. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15358182
|
Yuan ZY et al. |
PPAR-gamma ligands inhibit the expression of inflammatory cytokines and attenuate autoimmune myocarditis. |
2004 |
Chin. Med. J. |
pmid:15361304
|
Dugo L et al. |
15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria. |
2004 |
Eur. J. Pharmacol. |
pmid:15364008
|
Li L et al. |
Molecular mechanisms regulating the antifibrogenic protein heme-oxygenase-1 in human hepatic myofibroblasts. |
2004 |
J. Hepatol. |
pmid:15336443
|
Hirata Y et al. |
Anti-apoptotic and pro-apoptotic effect of NEPP11 on manganese-induced apoptosis and JNK pathway activation in PC12 cells. |
2004 |
Brain Res. |
pmid:15342272
|
Grau R et al. |
Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism. |
2004 |
Cancer Res. |
pmid:15289320
|
Yoshimura-Uchiyama C et al. |
Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2. |
2004 |
Clin. Exp. Allergy |
pmid:15298571
|
Cheng J et al. |
Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15325252
|
Luster AD and Tager AM |
T-cell trafficking in asthma: lipid mediators grease the way. |
2004 |
Nat. Rev. Immunol. |
pmid:15343370
|
Fernández-Tome M et al. |
p44/42(ERK1/2) MAPK and PLD activation by PGD2 preserves papillary phosphatidylcholine homeostasis. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15249196
|
Kanunfre CC et al. |
Ciglitizone and 15d PGJ2 induce apoptosis in Jurkat and Raji cells. |
2004 |
Int. Immunopharmacol. |
pmid:15251113
|
Berry EB et al. |
Differential effects of serum constituents on apoptosis induced by the cyclopentenone prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in WISH epithelial cells. |
2004 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:15253890
|
Morosetti R et al. |
The PPARgamma ligands PGJ2 and rosiglitazone show a differential ability to inhibit proliferation and to induce apoptosis and differentiation of human glioblastoma cell lines. |
2004 |
Int. J. Oncol. |
pmid:15254749
|
Hofnagel O et al. |
Proinflammatory cytokines regulate LOX-1 expression in vascular smooth muscle cells. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15271788
|
Park KS et al. |
Neuronal differentiation of embryonic midbrain cells by upregulation of peroxisome proliferator-activated receptor-gamma via the JNK-dependent pathway. |
2004 |
Exp. Cell Res. |
pmid:15212945
|
Shan ZZ et al. |
A potential role of 15-deoxy-delta(12,14)-prostaglandin J2 for induction of human articular chondrocyte apoptosis in arthritis. |
2004 |
J. Biol. Chem. |
pmid:15213234
|
Tanaka Y et al. |
Enhanced release of prostaglandin D2 during re-incubation of RAW 264.7 macrophage-like cells after treatment of both lipopolysaccharide and non-steroidal anti-inflammatory drugs. |
2004 |
Biol. Pharm. Bull. |
pmid:15256727
|
Jawerbaum A et al. |
Influence of peroxisome proliferator-activated receptor gamma activation by its endogenous ligand 15-deoxy Delta12,14 prostaglandin J2 on nitric oxide production in term placental tissues from diabetic women. |
2004 |
Mol. Hum. Reprod. |
pmid:15258247
|
Zhao ML et al. |
15-deoxy-delta (12,14)-PGJ2 inhibits astrocyte IL-1 signaling: inhibition of NF-kappaB and MAP kinase pathways and suppression of cytokine and chemokine expression. |
2004 |
J. Neuroimmunol. |
pmid:15265671
|
Zhang X et al. |
Peroxisome proliferator-activated receptor-gamma and its ligands attenuate biologic functions of human natural killer cells. |
2004 |
Blood |
pmid:15265789
|
Azuma Y et al. |
Induction of proliferation by 15-deoxy-delta12,14-prostaglandin J2 and the precursors in monocytic leukemia U937. |
2004 |
Pharmacology |
pmid:15240994
|
Zhang C et al. |
The novel synthetic oleanane triterpenoid CDDO (2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid) induces apoptosis in Mycosis fungoides/Sézary syndrome cells. |
2004 |
J. Invest. Dermatol. |
pmid:15245439
|
Siavash H et al. |
Targeting of epidermal growth factor receptor by cyclopentenone prostaglandin 15-Deoxy-Delta12,14-prostaglandin J2 in human oral squamous carcinoma cells. |
2004 |
Cancer Lett. |
pmid:15194221
|
Li Z et al. |
Delta12-Prostaglandin J2 inhibits the ubiquitin hydrolase UCH-L1 and elicits ubiquitin-protein aggregation without proteasome inhibition. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15194490
|
Han S et al. |
Ligands of peroxisome proliferator-activated receptor gamma inhibit lung cancer cell growth and induce apoptosis by stimulation of P21 expression. |
2004 |
Chest |
pmid:15136464
|
Collin M et al. |
Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15-deoxydelta12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin. |
2004 |
Crit. Care Med. |
pmid:15090969
|
Baolin L et al. |
Resveratrol inhibits the release of mediators from bone marrow-derived mouse mast cells in vitro. |
2004 |
Planta Med. |
pmid:15095144
|
Zang C et al. |
Peroxisome proliferator-activated receptor gamma ligands induce growth inhibition and apoptosis of human B lymphocytic leukemia. |
2004 |
Leuk. Res. |
pmid:15109539
|
Jakob M et al. |
Chondrogenesis of expanded adult human articular chondrocytes is enhanced by specific prostaglandins. |
2004 |
Rheumatology (Oxford) |
pmid:15113997
|
Verrier E et al. |
PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: role of diacylglycerol kinase. |
2004 |
Circ. Res. |
pmid:15117825
|
Leung WK et al. |
Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells. |
2004 |
Gut |
pmid:14960510
|
Mouihate A et al. |
A novel antipyretic action of 15-deoxy-Delta12,14-prostaglandin J2 in the rat brain. |
2004 |
J. Neurosci. |
pmid:14960602
|
Chatterjee PK et al. |
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure. |
2004 |
Cardiovasc. Res. |
pmid:14962493
|
Brummond KM et al. |
The first total synthesis of 15-deoxy-Delta12,14-prostaglandin J2 and the unambiguous assignment of the C14 stereochemistry. |
2004 |
Org. Lett. |
pmid:14723515
|