Kang DS et al. |
15-deoxy-Delta12,14-prostaglandin J2 induces renal epithelial cell death through NF-kappaB-dependent and MAPK-independent mechanism. |
2006 |
Toxicol. Appl. Pharmacol. |
pmid:16890972
|
Nakata S et al. |
15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis. |
2006 |
Mol. Cancer Ther. |
pmid:16891469
|
Wang XS and Lau HY |
Beta-adrenoceptor-mediated inhibition of mediator release from human peripheral blood-derived mast cells. |
2006 |
Clin. Exp. Pharmacol. Physiol. |
pmid:16895550
|
Zhang A et al. |
Prostaglandin D2 inhibits TGF-beta1-induced epithelial-to-mesenchymal transition in MDCK cells. |
2006 |
Am. J. Physiol. Renal Physiol. |
pmid:16896186
|
Broide DH et al. |
Airway levels of mast cell-derived mediators in exercise-induced asthma. |
1990 |
Am. Rev. Respir. Dis. |
pmid:1689974
|
Schratl P et al. |
Hierarchy of eosinophil chemoattractants: role of p38 mitogen-activated protein kinase. |
2006 |
Eur. J. Immunol. |
pmid:16906532
|
Ciucci A et al. |
Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway. |
2006 |
Mol. Pharmacol. |
pmid:16908599
|
Undem BJ et al. |
Inhibition by adenosine 3':5'-monophosphate of eicosanoid and platelet-activating factor biosynthesis in the mouse PT-18 mast cell. |
1990 |
J. Biol. Chem. |
pmid:1691175
|
Moulin D et al. |
Effect of peroxisome proliferator activated receptor (PPAR)gamma agonists on prostaglandins cascade in joint cells. |
2006 |
Biorheology |
pmid:16912428
|
Yeh CH et al. |
Cardiomyocytic apoptosis following global cardiac ischemia and reperfusion can be attenuated by peroxisome proliferator-activated receptor alpha but not gamma activators. |
2006 |
Shock |
pmid:16912651
|
Guyer BJ et al. |
Mast cell inhibitor R112 is well tolerated and affects prostaglandin D2 but not other mediators, symptoms, or nasal volumes in a nasal challenge model of allergic rhinitis. |
2006 May-Jun |
Allergy Asthma Proc |
pmid:16913263
|
Ye F et al. |
Quantitative characterization of 15-deoxy-delta(12,14)-prostaglandin J2 in regulating EGFPSmad2 translocation in CHO cells through PPARgamma/TGFbeta/Smad2 pathway. |
2006 |
Cell. Physiol. Biochem. |
pmid:16914899
|
Eggleston PA et al. |
Disassociation of the release of histamine and arachidonic acid metabolites from osmotically activated basophils and human lung mast cells. |
1990 |
Am. Rev. Respir. Dis. |
pmid:1691604
|
Lee JJ et al. |
Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization. |
2006 |
Vascul. Pharmacol. |
pmid:16916624
|
Ulven T and Kostenis E |
Targeting the prostaglandin D2 receptors DP and CRTH2 for treatment of inflammation. |
2006 |
Curr Top Med Chem |
pmid:16918458
|
Theiner G et al. |
The mast cell mediator PGD2 suppresses IL-12 release by dendritic cells leading to Th2 polarized immune responses in vivo. |
2006 |
Immunobiology |
pmid:16920486
|
Proud D et al. |
Inflammatory mediator release on conjunctival provocation of allergic subjects with allergen. |
1990 |
J. Allergy Clin. Immunol. |
pmid:1692049
|
Miadonna A et al. |
Mediator release after endobronchial antigen challenge in patients with respiratory allergy. |
1990 |
J. Allergy Clin. Immunol. |
pmid:1692050
|
Peeraully MR et al. |
Prostaglandin D2 and J2-series (PGJ2, Delta12-PGJ2) prostaglandins stimulate IL-6 and MCP-1, but inhibit leptin, expression and secretion by 3T3-L1 adipocytes. |
2006 |
Pflugers Arch. |
pmid:16924534
|
Eucker J et al. |
Peroxisome proliferator-activated receptor-gamma ligands inhibit proliferation and induce apoptosis in mantle cell lymphoma. |
2006 |
Anticancer Drugs |
pmid:16926626
|
Schulman ES et al. |
Histochemical heterogeneity of dispersed human lung mast cells. |
1990 |
J. Immunol. |
pmid:1692857
|
Fox CC et al. |
Enhancement of human intestinal mast cell mediator release in active ulcerative colitis. |
1990 |
Gastroenterology |
pmid:1693122
|
Ikai K and Fukushima M |
Effects of cytotoxic prostaglandin, delta 12-PGJ2 on protein synthesis and cytoskeleton in transformed epidermal cells in culture. |
1990 |
Arch. Dermatol. Res. |
pmid:1693839
|
Willermain F et al. |
15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16939878
|
Lim HJ et al. |
PPARgamma activation induces CD36 expression and stimulates foam cell like changes in rVSMCs. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16939881
|
Chiba T et al. |
Prostaglandin D2 induces IL-8 and GM-CSF by bronchial epithelial cells in a CRTH2-independent pathway. |
2006 |
Int. Arch. Allergy Immunol. |
pmid:16940740
|
Meyers CD et al. |
Nicotinic acid induces secretion of prostaglandin D2 in human macrophages: an in vitro model of the niacin flush. |
2007 |
Atherosclerosis |
pmid:16945375
|
Goya K et al. |
The thiazolidinedione drug troglitazone up-regulates nitric oxide synthase expression in vascular endothelial cells. |
2006 Sep-Oct |
J. Diabetes Complicat. |
pmid:16949522
|
Ashby B |
Novel mechanism of heterologous desensitization of adenylate cyclase: prostaglandins bind with different affinities to both stimulatory and inhibitory receptors on platelets. |
1990 |
Mol. Pharmacol. |
pmid:1695318
|
Rollins MD et al. |
Anti-inflammatory effects of PPAR-gamma agonists directly correlate with PPAR-gamma expression during acute pancreatitis. |
2006 Sep-Oct |
J. Gastrointest. Surg. |
pmid:16966031
|
Aquila S et al. |
Peroxisome proliferator-activated receptor (PPAR)gamma is expressed by human spermatozoa: its potential role on the sperm physiology. |
2006 |
J. Cell. Physiol. |
pmid:16972250
|
Gayarre J et al. |
Addition of electrophilic lipids to actin alters filament structure. |
2006 |
Biochem. Biophys. Res. Commun. |
pmid:16979589
|
Urade Y and Mohri I |
[Sleep and brain function]. |
2006 |
No To Hattatsu |
pmid:16986732
|
Kim EH and Surh YJ |
15-deoxy-Delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors. |
2006 |
Biochem. Pharmacol. |
pmid:16987499
|
Atkins PC et al. |
In vivo antigen-induced cutaneous mediator release: simultaneous comparisons of histamine, tryptase, and prostaglandin D2 release and the effect of oral corticosteroid administration. |
1990 |
J. Allergy Clin. Immunol. |
pmid:1698845
|
Pipkorn U |
H1-antagonists as a tool in clarifying the pathophysiology of nasal allergy. |
1990 |
Clin. Exp. Allergy |
pmid:1699643
|
Egan K and FitzGerald GA |
Eicosanoids and the vascular endothelium. |
2006 |
Handb Exp Pharmacol |
pmid:16999220
|
Sugimoto M et al. |
Time course changes of scratching counts, dermatitis symptoms, and levels of cutaneous prostaglandins in NC/Nga mice. |
2006 |
Exp. Dermatol. |
pmid:17002684
|
Feldon SE et al. |
Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytes. |
2006 |
Am. J. Pathol. |
pmid:17003477
|
Cho WH et al. |
15-deoxy-(Delta12,14)-prostaglandin J2 (15d-PGJ2) induces cell death through caspase-independent mechanism in A172 human glioma cells. |
2006 |
Neurochem. Res. |
pmid:17006759
|
Payne SG et al. |
The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors. |
2007 |
Blood |
pmid:17008548
|
Maciejewski-Lenoir D et al. |
Langerhans cells release prostaglandin D2 in response to nicotinic acid. |
2006 |
J. Invest. Dermatol. |
pmid:17008871
|
Knapp HR |
Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor. |
1990 |
N. Engl. J. Med. |
pmid:1701029
|
Ray DM et al. |
The peroxisome proliferator-activated receptor gamma (PPARgamma) ligands 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms. |
2006 |
J. Immunol. |
pmid:17015690
|
Marriott DR et al. |
Substance P-induced release of prostaglandins from astrocytes: regional specialisation and correlation with phosphoinositol metabolism. |
1991 |
J. Neurochem. |
pmid:1702831
|
Kamagata C et al. |
15-deoxy-Delta(12,14)-prostaglandin J2 inhibits G2-M phase progression in human breast cancer cells via the down-regulation of cyclin B1 and survivin expression. |
2007 |
Breast Cancer Res. Treat. |
pmid:17028981
|
Fox CC et al. |
Modulation of mediator release from human intestinal mast cells by sulfasalazine and 5-aminosalicylic acid. |
1991 |
Dig. Dis. Sci. |
pmid:1703070
|
Cossette C et al. |
Agonist and antagonist effects of 15R-prostaglandin (PG) D2 and 11-methylene-PGD2 on human eosinophils and basophils. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17041009
|
Sandig H et al. |
Contrary prostaglandins: the opposing roles of PGD2 and its metabolites in leukocyte function. |
2007 |
J. Leukoc. Biol. |
pmid:17043246
|
Okuda-Ashitaka E et al. |
Cyclic AMP-mediated inhibition of cell growth by prostaglandin D2 in a fibroblastic cell line (EBTr). |
1990 |
Eicosanoids |
pmid:1705811
|
Diaz BL et al. |
Group V secretory phospholipase A2 amplifies the induction of cyclooxygenase 2 and delayed prostaglandin D2 generation in mouse bone marrow culture-derived mast cells in a strain-dependent manner. |
2006 |
Biochim. Biophys. Acta |
pmid:17064958
|
Qin S et al. |
Protection of RPE cells from oxidative injury by 15-deoxy-delta12,14-prostaglandin J2 by augmenting GSH and activating MAPK. |
2006 |
Invest. Ophthalmol. Vis. Sci. |
pmid:17065531
|
Gyles SL et al. |
A dominant role for chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants. |
2006 |
Immunology |
pmid:17067313
|
Gulliksson M et al. |
Release of prostaglandin D2 and leukotriene C4 in response to hyperosmolar stimulation of mast cells. |
2006 |
Allergy |
pmid:17073880
|
Phulwani NK et al. |
15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway. |
2006 |
J. Neurochem. |
pmid:17074064
|
Liu JJ et al. |
Downregulation of cyclooxygenase-2 expression and activation of caspase-3 are involved in peroxisome proliferator-activated receptor-gamma agonists induced apoptosis in human monocyte leukemia cells in vitro. |
2007 |
Ann. Hematol. |
pmid:17089125
|
Jin YR et al. |
Antiplatelet activity of hesperetin, a bioflavonoid, is mainly mediated by inhibition of PLC-gamma2 phosphorylation and cyclooxygenase-1 activity. |
2007 |
Atherosclerosis |
pmid:17092506
|
Qu WM et al. |
Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:17093043
|
Nicoll-Griffith DA et al. |
In vitro biotransformations of the prostaglandin D2 (DP) antagonist MK-0524 and synthesis of metabolites. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17095220
|
Rahman A et al. |
Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats. |
2007 |
Eur. J. Pharmacol. |
pmid:17112500
|
GarcÃa-Bueno B et al. |
Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats. |
2007 |
Neuropsychopharmacology |
pmid:17119541
|
Kim SJ et al. |
Effects of methyl gallate on arachidonic acid metabolizing enzymes: Cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. |
2006 |
Arch. Pharm. Res. |
pmid:17121182
|
Raphael GD et al. |
The pathophysiology of rhinitis. V. Sources of protein in allergen-induced nasal secretions. |
1991 |
J. Allergy Clin. Immunol. |
pmid:1712803
|
White MV et al. |
Hydrocortisone inhibits rat basophilic leukemia cell mediator release induced by neutrophil-derived histamine releasing activity as well as by anti-IgE. |
1991 |
J. Immunol. |
pmid:1712816
|
Huang ZL et al. |
Prostaglandins and adenosine in the regulation of sleep and wakefulness. |
2007 |
Curr Opin Pharmacol |
pmid:17129762
|
Akabane H et al. |
Effects of salmeterol xinafoate and fluticasone propionate on immunological activation of human cultured mast cells. |
2006 |
Allergol Int |
pmid:17130681
|
Ishimura M et al. |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea. |
2006 |
Allergol Int |
pmid:17130683
|
Kim HY and Kim HS |
Upregulation of MIP-2 (CXCL2) expression by 15-deoxy-Delta(12,14)-prostaglandin J(2) in mouse peritoneal macrophages. |
2007 |
Immunol. Cell Biol. |
pmid:17130903
|
Arai I et al. |
Effects of TS-022, a newly developed prostanoid DP1 receptor agonist, on experimental pruritus, cutaneous barrier disruptions and atopic dermatitis in mice. |
2007 |
Eur. J. Pharmacol. |
pmid:17141215
|
Berruyer C et al. |
Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity. |
2006 |
J. Exp. Med. |
pmid:17145956
|
Chambers KT et al. |
PGJ2-stimulated beta-cell apoptosis is associated with prolonged UPR activation. |
2007 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:17148750
|
Mazid MA et al. |
Endogenous 15-deoxy-Delta(12,14)-prostaglandin J(2) synthesized by adipocytes during maturation phase contributes to upregulation of fat storage. |
2006 |
FEBS Lett. |
pmid:17150216
|
Tanaka Y et al. |
Hepatic ischemia-reperfusion induces renal heme oxygenase-1 via NF-E2-related factor 2 in rats and mice. |
2007 |
Mol. Pharmacol. |
pmid:17151289
|
Rousseaux C and Desreumaux P |
[The peroxisome-proliferator-activated gamma receptor and chronic inflammatory bowel disease (PPARgamma and IBD)]. |
2006 |
J. Soc. Biol. |
pmid:17151549
|
Massey WA et al. |
Human uterine mast cells. Isolation, purification, characterization, ultrastructure, and pharmacology. |
1991 |
J. Immunol. |
pmid:1715365
|
Fulzele SV et al. |
15-Deoxy-Delta12,14-prostaglandin J2 enhances docetaxel anti-tumor activity against A549 and H460 non-small-cell lung cancer cell lines and xenograft tumors. |
2007 |
Anticancer Drugs |
pmid:17159504
|
Hortobágyi L et al. |
Adaptation of the hypothalamic blood flow to chronic nitric oxide deficiency is independent of vasodilator prostanoids. |
2007 |
Brain Res. |
pmid:17161389
|
Kang MA et al. |
Up-regulation of skeletal muscle LIM protein 1 gene by 25-hydroxycholesterol may mediate morphological changes of rat aortic smooth muscle cells. |
2007 |
Life Sci. |
pmid:17161435
|
Arai I |
[Role of cutaneous prostaglandin D2 production on scratching dermatitis in mice]. |
2006 |
Nippon Yakurigaku Zasshi |
pmid:17167214
|
Sánchez-Gómez FJ et al. |
Direct evidence for the covalent modification of glutathione-S-transferase P1-1 by electrophilic prostaglandins: implications for enzyme inactivation and cell survival. |
2007 |
Arch. Biochem. Biophys. |
pmid:17169324
|
Fernández PL |
[Stress and inflammatory bowell disease (I.B.D). Therapeutic strategies]. |
2006 |
An R Acad Nac Med (Madr) |
pmid:17172222
|
Castellani ML et al. |
Rat basophilic leukemia cells (RBL-2H3) generate prostaglandin D2 (PGD2) after regulated upon activation, normal T-cell expressed and secreted (RANTES) activation. |
2006 Oct-Dec |
Int. J. Biol. Markers |
pmid:17177158
|
Zhang YF et al. |
Peroxisome proliferator-activated receptor-gamma is expressed by rat peritoneal mesothelial cells: its potential role in peritoneal cavity local defense. |
2006 |
Am. J. Nephrol. |
pmid:17183189
|
Watanabe T et al. |
Characterization of prostaglandin and thromboxane receptors expressed on a megakaryoblastic leukemia cell line, MEG-01s. |
1991 |
Blood |
pmid:1718495
|
Perreault T and De Marte J |
Endothelin-1 has a dilator effect on neonatal pig pulmonary vasculature. |
1991 |
J. Cardiovasc. Pharmacol. |
pmid:1719291
|
van der Donk EM et al. |
Leukotriene C4 formation by enriched human basophil preparations from normal and asthmatic subjects. |
1991 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:1719566
|
Xue L et al. |
Inhibition of PI3K and calcineurin suppresses chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)-dependent responses of Th2 lymphocytes to prostaglandin D(2). |
2007 |
Biochem. Pharmacol. |
pmid:17196174
|
Van Hecken A et al. |
The effect of MK-0524, a prostaglandin D(2) receptor antagonist, on prostaglandin D (2)-induced nasal airway obstruction in healthy volunteers. |
2007 |
Eur. J. Clin. Pharmacol. |
pmid:17200838
|
Mathew B et al. |
Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages. |
2007 |
Am. J. Respir. Cell Mol. Biol. |
pmid:17204585
|
Gallant MA et al. |
Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2. |
2007 |
Eur. J. Pharmacol. |
pmid:17207480
|
Rehan VK et al. |
In utero nicotine exposure alters fetal rat lung alveolar type II cell proliferation, differentiation, and metabolism. |
2007 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:17215434
|
Murakami M et al. |
Group II phospholipase A2 inhibitors suppressed lysophosphatidylserine-dependent degranulation of rat peritoneal mast cells. |
1991 |
Biochem. Biophys. Res. Commun. |
pmid:1721808
|
Myers AC et al. |
Influence of antigen on membrane properties of guinea pig bronchial ganglion neurons. |
1991 |
J. Appl. Physiol. |
pmid:1721906
|
Stellato C et al. |
General anaesthetics induce only histamine release selectively from human mast cells. |
1991 |
Br J Anaesth |
pmid:1722691
|
Ruano D et al. |
Family-based and case-control studies reveal no association of lipocalin-type prostaglandin D2 synthase with schizophrenia. |
2007 |
Am. J. Med. Genet. B Neuropsychiatr. Genet. |
pmid:17230501
|
Walmrath D et al. |
Intravascular anti-IgE challenge in perfused lungs: mediator release and vascular pressor response. |
1991 |
J. Appl. Physiol. |
pmid:1723406
|
Moreira V et al. |
Bothrops jararaca and Crotalus durissus terrificus venoms elicit distinct responses regarding to production of prostaglandins E2 and D2, and expression of cyclooxygenases. |
2007 |
Toxicon |
pmid:17241651
|
Liu M et al. |
Focal cerebral ischemia/reperfusion injury in mice induces hematopoietic prostaglandin D synthase in microglia and macrophages. |
2007 |
Neuroscience |
pmid:17241746
|
Tinfo N and Komar C |
Potential role for peroxisome proliferator-activated receptor gamma in regulating luteal lifespan in the rat. |
2007 |
Reproduction |
pmid:17244745
|
Hagens WI et al. |
Targeting 15d-prostaglandin J2 to hepatic stellate cells: two options evaluated. |
2007 |
Pharm. Res. |
pmid:17245650
|