PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Stroke D020521 32 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Fetal Weight D020567 12 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Coronary Restenosis D023903 10 associated lipids
Tauopathies D024801 6 associated lipids
Mastocytosis, Systemic D034721 1 associated lipids
Decapitation D049248 2 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Atherosclerosis D050197 85 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PGD2

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Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Jović N et al. Do prostaglandins E2, F2 alpha and D2 have a role in the development of idiopathic trigeminal neuralgia? 1996 May-Jun Vojnosanit Pregl pmid:9174396
Reddy ST et al. Analysis of the secretory phospholipase A2 that mediates prostaglandin production in mast cells. 1997 J. Biol. Chem. pmid:9153207
Teixeira MM et al. Characterization of the prostanoid receptors mediating inhibition of PAF-induced aggregation of guinea-pig eosinophils. 1997 Br. J. Pharmacol. pmid:9146890
AL-Hader AA et al. Novel expression of functional luteinizing hormone/chorionic gonadotropin receptors in cultured glial cells from neonatal rat brains. 1997 Biol. Reprod. pmid:9116153
Minami T et al. Absence of prostaglandin E2-induced hyperalgesia in NMDA receptor epsilon subunit knockout mice. 1997 Br. J. Pharmacol. pmid:9113374
Taber DF et al. A nomenclature system for the isoprostanes. 1997 Prostaglandins pmid:9112285
Ram A et al. CSF levels of prostaglandins, especially the level of prostaglandin D2, are correlated with increasing propensity towards sleep in rats. 1997 Brain Res. pmid:9098570
Kanamori Y et al. Migration of neutrophils from blood to tissue: alteration of modulatory effects of prostanoid on superoxide generation in rabbits and humans. 1997 Life Sci. pmid:9096262
Franzese O et al. Functional antagonism between IL-2 and PGA1 or PGJ2 in the control of proliferation of human cord blood-derived mononuclear cells. 1996 Int. J. Immunopharmacol. pmid:9089005
Abran D et al. Regulation of prostanoid vasomotor effects and receptors in choroidal vessels of newborn pigs. 1997 Am. J. Physiol. pmid:9087666