PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Stroke D020521 32 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Fetal Weight D020567 12 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Coronary Restenosis D023903 10 associated lipids
Tauopathies D024801 6 associated lipids
Mastocytosis, Systemic D034721 1 associated lipids
Decapitation D049248 2 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Atherosclerosis D050197 85 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PGD2

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Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Akarsu ES et al. Inhibition of pentylenetetrazol-induced seizures in rats by prostaglandin D2. 1998 Epilepsy Res. pmid:9551845
Fukushima S et al. [Pharmaceutical and pharmacological development of antitumor prostaglandins]. 1998 Nippon Rinsho pmid:9549353
Austin S et al. Induction of the nuclear orphan receptor RORgamma during adipocyte differentiation of D1 and 3T3-L1 cells. 1998 Cell Growth Differ. pmid:9543393
Liao CH et al. Effect of PP1D-1, a synthetic antiplatelet compound, on rabbit platelets. 1998 Jpn. J. Pharmacol. pmid:9541276
Boie Y et al. Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. 1997 Eur. J. Pharmacol. pmid:9537820
Rossi AG et al. Regulation of macrophage phagocytosis of apoptotic cells by cAMP. 1998 J. Immunol. pmid:9531319
Mezei Z et al. Platelet eicosanoids and the effect of captopril in blood pressure regulation. 1997 Eur. J. Pharmacol. pmid:9527508
Ward PE et al. Niacin skin flush in schizophrenia: a preliminary report. 1998 Schizophr. Res. pmid:9516668
Giardiello FM et al. Prostaglandin levels in human colorectal mucosa: effects of sulindac in patients with familial adenomatous polyposis. 1998 Dig. Dis. Sci. pmid:9512123
Kimura K et al. Modulation of platelet activating factor-induced glycogenolysis in the perfused rat liver after administration of endotoxin in vivo. 1998 J. Biochem. pmid:9504421