PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Trigeminal Neuralgia D014277 1 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
Respiratory Sounds D012135 3 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Choroid Diseases D015862 2 associated lipids
Wounds, Stab D014951 3 associated lipids
Tauopathies D024801 6 associated lipids
Mastocytosis, Systemic D034721 1 associated lipids
Coronavirus Infections D018352 4 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PGD2

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Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Hardy E et al. Magnesium modifies the responses of platelets to inhibitory agents which act via cAMP. 1995 Thromb. Haemost. pmid:8560425
Osaka T and Hayaishi O Prostaglandin D2 modulates sleep-related and noradrenaline-induced activity of preoptic and basal forebrain neurons in the rat. 1995 Neurosci. Res. pmid:8545074
Daugschies A Oesophagostomum dentatum: population dynamics and synthesis of prostanoids by histotropic stages cultured in vitro. 1995 Exp. Parasitol. pmid:8542999
Kliewer SA et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. 1995 Cell pmid:8521498
Forman BM et al. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. 1995 Cell pmid:8521497
Itabashi S et al. Late asthmatic response causes peripheral airway hyperresponsiveness in dogs treated with metopirone. 1993 Int. Arch. Allergy Immunol. pmid:8508057
Rangachari PK and Betti PA Biological activity of metabolites of PGD2 on canine proximal colon. 1993 Am. J. Physiol. pmid:8498516
Xu L et al. Effect of culture conditions on mast cell eicosanoid synthesis. 1993 Prostaglandins pmid:8493360
Fredberg JJ et al. Tissue resistance and the contractile state of lung parenchyma. 1993 J. Appl. Physiol. pmid:8482682
Kim IK et al. Prostaglandin A2 and delta 12-prostaglandin J2 induce apoptosis in L1210 cells. 1993 FEBS Lett. pmid:8477853