| MeSH term | MeSH ID | Detail |
|---|---|---|
| Angioedemas, Hereditary | D054179 | 2 associated lipids |
| Idiopathic Pulmonary Fibrosis | D054990 | 4 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
| Pulmonary Aspergillosis | D055732 | 1 associated lipids |
| Asthma, Aspirin-Induced | D055963 | 2 associated lipids |
| Airway Remodeling | D056151 | 3 associated lipids |
| Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
| Plaque, Atherosclerotic | D058226 | 7 associated lipids |
| Fetal Alcohol Spectrum Disorders | D063647 | 6 associated lipids |
PGD2
Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.
Cross Reference
Introduction
To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PGD2?
PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PGD2
PubChem Associated disorders and diseases
What pathways are associated with PGD2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PGD2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with PGD2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PGD2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with PGD2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PGD2?
Knock-out
Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).
Rodent Model
Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with PGD2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kanamori S et al. | Effects of dietary fibre on dimethylhydrazine-induced changes in prostanoid concentrations in rat colonic mucosa. | 1995 | Clin. Exp. Pharmacol. Physiol. | pmid:8575110 |
| Radziszewski W et al. | Nitric oxide donors induce extrusion of cyclic GMP from isolated human blood platelets by a mechanism which may be modulated by prostaglandins. | 1995 | Int. J. Cardiol. | pmid:8586470 |
| Kane GC et al. | Insights into IgE-mediated lung inflammation derived from a study employing a 5-lipoxygenase inhibitor. | 1995 | Prostaglandins | pmid:8588068 |
| Sato T et al. | Decreased hypothalamic prostaglandin D2 and prostaglandin E2 contents during isoflurane anaesthesia in rats. | 1995 | Can J Anaesth | pmid:8590493 |
| Usatiuk PV et al. | [Content of prostaglandins E2 and F1alpha in small intestine epithelium in cattle as a function of age and pathology in non-infectious diarrhea]. | 1995 Mar-Apr | Ukr. Biokhim. Zh. | pmid:8592776 |
| Pandey HP et al. | Concentration of prostaglandin D2 in cerebrospinal fluid exhibits a circadian alteration in conscious rats. | 1995 | Biochem. Mol. Biol. Int. | pmid:8595382 |
| Vesin MF et al. | Biosynthesis of prostaglandin D2 by motoneurons and dorsal horn microneurons: a biochemical and high resolution immunocytochemical study in chick spinal cord. | 1995 | Neuroscience | pmid:8596663 |
| Small P and Barrett D | Evaluation of dust and dust mite nasal provocation. | 1995 | Ann. Allergy Asthma Immunol. | pmid:8603280 |
| Rozera C et al. | Inhibition of HIV-1 replication by cyclopentenone prostaglandins in acutely infected human cells. Evidence for a transcriptional block. | 1996 | J. Clin. Invest. | pmid:8621762 |
| Seghaye MC et al. | Histamine liberation related to cardiopulmonary bypass in children: possible relation to transient postoperative arrhythmias. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8622322 |
| Longphre M et al. | PAF-induced airways hyperreactivity is modulated by mast cells in mice. | 1996 | Am. J. Respir. Cell Mol. Biol. | pmid:8624251 |
| Chilton FH et al. | Antigen-induced generation of lyso-phospholipids in human airways. | 1996 | J. Exp. Med. | pmid:8642333 |
| Odani N et al. | Induction of protein disulfide isomerase mRNA by delta 12-prostaglandin J2. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8645293 |
| Genovese A et al. | Role of mast cells, basophils and their mediators in adverse reactions to general anesthetics and radiocontrast media. | 1996 | Int. Arch. Allergy Immunol. | pmid:8645973 |
| Weidenbach H et al. | Reduction of bile secretion by prostaglandins in the rat in vivo. | 1996 | Life Sci. | pmid:8649182 |
| Satoh S et al. | Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8650205 |
| Kawamoto K | [Flow cytometric analysis of cell cycle for the action mechanism of antineoplastic agents]. | 1995 | Hum. Cell | pmid:8652450 |
| Odani N et al. | Regulation of BiP gene expression by cyclopentenone prostaglandins through unfolded protein response element. | 1996 | J. Biol. Chem. | pmid:8663202 |
| Shalev A and Meier CA | Peroxisome proliferator-activated receptors: a nuclear hormone receptor involved in adipocyte differentiation and lipid homeostasis. | 1996 | Eur. J. Endocrinol. | pmid:8664970 |
| de Paulis A et al. | Human synovial mast cells. I. Ultrastructural in situ and in vitro immunologic characterization. | 1996 | Arthritis Rheum. | pmid:8670335 |