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Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants: elevation of prostaglandin D2 levels. |
2007 |
Arthritis Res. Ther. |
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The anti-pruritic efficacy of TS-022, a prostanoid DP1 receptor agonist, is dependent on the endogenous prostaglandin D2 level in the skin of NC/Nga mice. |
2007 |
Eur. J. Pharmacol. |
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Family-based and case-control studies reveal no association of lipocalin-type prostaglandin D2 synthase with schizophrenia. |
2007 |
Am. J. Med. Genet. B Neuropsychiatr. Genet. |
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15-deoxy-Delta 12,14-ProstaglandinJ2 regulates dedifferentiation through peroxisome proliferator-activated receptor-gamma-dependent pathway but not COX-2 expression in articular chondrocytes. |
2007 |
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[Effect of peroxisome proliferators-activated receptor gamma ligands on cytotrophoblast invasion in first trimester pregnancy]. |
2007 |
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PGJ2 inhibition of LPS-induced inflammatory mediator expression from rat alveolar macrophages. |
2007 |
J. Toxicol. Environ. Health Part A |
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Quantitative analysis of eosinophil chemotaxis tracked using a novel optical device -- TAXIScan. |
2007 |
J. Immunol. Methods |
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Possible novel receptor for PGD2 on human bronchial epithelial cells. |
2007 |
Int. Arch. Allergy Immunol. |
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15-Deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) mediates repression of TNF-alpha by decreasing levels of acetylated histone H3 and H4 at its promoter. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17532302
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Lin MS et al. |
Activation of peroxisome proliferator-activated receptor gamma inhibits cell growth via apoptosis and arrest of the cell cycle in human colorectal cancer. |
2007 |
J Dig Dis |
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Role of prostaglandins on mechanical scratching-induced cutaneous barrier disruption in mice. |
2007 |
Exp. Dermatol. |
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Functional characteristics of the porcine colonic epithelium following transportation stress and Salmonella infection. |
2007 |
Scand. J. Gastroenterol. |
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Wang XS et al. |
PGE suppresses excessive anti-IgE induced cysteinyl leucotrienes production in mast cells of patients with aspirin exacerbated respiratory disease. |
2007 |
Allergy |
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Monroy MA et al. |
THE PPARgamma ligand 15d-PGJ2 modulates macrophage activation after injury in a murine trauma model. |
2007 |
Shock |
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[The role of lipid mediators in allergic diseases]. |
2007 |
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Peroxisome proliferator-activated receptor gamma is required for the inhibitory effect of ciglitazone but not 15-deoxy-Delta 12,14-prostaglandin J2 on the NFkappaB pathway in human endothelial cells. |
2007 |
Shock |
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Deficiency of cyclooxygenases transcripts in cultured primary bronchial epithelial cells of aspirin-sensitive asthmatics. |
2007 |
J. Physiol. Pharmacol. |
pmid:17622692
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PPARgamma inhibits osteogenesis via the down-regulation of the expression of COX-2 and iNOS in rats. |
2007 |
Bone |
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Inhibition of trail gene expression by cyclopentenonic prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in T lymphocytes. |
2007 |
Mol. Pharmacol. |
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Induction and function of lipocalin prostaglandin D synthase in host immunity. |
2007 |
J. Immunol. |
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[Cysteine-mediated signaling pathway by a novel electrophilic compound, NEPP11]. |
2007 |
Seikagaku |
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PPAR-gamma agonists induce the expression of VEGF and its receptors in cultured cardiac myofibroblasts. |
2007 |
Cardiovasc. Res. |
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ERK-1/-2 and p38 kinase oppositely regulate 15-deoxy-delta(12,14)-prostaglandinJ(2)-Induced PPAR-gamma activation that mediates dedifferentiation but not cyclooxygenase-2 expression in articular chondrocytes. |
2007 |
J. Korean Med. Sci. |
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Nicotinic acid induces secretion of prostaglandin D2 in human macrophages: an in vitro model of the niacin flush. |
2007 |
Atherosclerosis |
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Anti-inflammatory effects of PPAR-gamma agonists directly correlate with PPAR-gamma expression during acute pancreatitis. |
2006 Sep-Oct |
J. Gastrointest. Surg. |
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The thiazolidinedione drug troglitazone up-regulates nitric oxide synthase expression in vascular endothelial cells. |
2006 Sep-Oct |
J. Diabetes Complicat. |
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Rat basophilic leukemia cells (RBL-2H3) generate prostaglandin D2 (PGD2) after regulated upon activation, normal T-cell expressed and secreted (RANTES) activation. |
2006 Oct-Dec |
Int. J. Biol. Markers |
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15-Deoxy-Delta(12,14)-prostaglandin J(2) and troglitazone regulation of the release of phospholipid metabolites, inflammatory cytokines and proteases from human gestational tissues. |
2006 Nov-Dec |
Placenta |
pmid:16434095
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Twenty-fifth anniversary of the discovery of somnogenic activity of prostaglandin D2: sleep research directed by Osamu Hayaishi. |
2006 May-Jun |
IUBMB Life |
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Presence and characterization of prostaglandin D2-related molecules in nasal mucosa of patients with allergic rhinitis. |
2006 May-Jun |
Am J Rhinol |
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Mast cell inhibitor R112 is well tolerated and affects prostaglandin D2 but not other mediators, symptoms, or nasal volumes in a nasal challenge model of allergic rhinitis. |
2006 May-Jun |
Allergy Asthma Proc |
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Kim SJ et al. |
Effects of methyl gallate on arachidonic acid metabolizing enzymes: Cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. |
2006 |
Arch. Pharm. Res. |
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Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity. |
2006 |
J. Exp. Med. |
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Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:17093043
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[Role of cutaneous prostaglandin D2 production on scratching dermatitis in mice]. |
2006 |
Nippon Yakurigaku Zasshi |
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Akabane H et al. |
Effects of salmeterol xinafoate and fluticasone propionate on immunological activation of human cultured mast cells. |
2006 |
Allergol Int |
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Ishimura M et al. |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea. |
2006 |
Allergol Int |
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On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2. |
2006 |
Mol. Pharmacol. |
pmid:16418339
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High levels of filamentous actin and apoptosis correlate with mast cell refractoriness under alloxan-evoked diabetes. |
2006 |
Life Sci. |
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Effects of 15d-PGJ(2) on VEGF-induced angiogenic activities and expression of VEGF receptors in endothelial cells. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16647637
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Anti-inflammatory activity of Ailanthus altissima in ovalbumin-induced lung inflammation. |
2006 |
Biol. Pharm. Bull. |
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Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher. |
2006 |
J. Neurosci. |
pmid:16624958
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Effects of 15-deoxy-Delta12,14-prostaglandin-J2 during hyperdynamic porcine endotoxemia. |
2006 |
Intensive Care Med |
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Peroxisome proliferator-activated receptor-gamma and retinoic acid X receptor alpha represses the TGFbeta1 gene via PTEN-mediated p70 ribosomal S6 kinase-1 inhibition: role for Zf9 dephosphorylation. |
2006 |
Mol. Pharmacol. |
pmid:16611854
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Rockwell CE et al. |
Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor gamma independently of cannabinoid receptors 1 and 2. |
2006 |
Mol. Pharmacol. |
pmid:16611855
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Arnold R and König W |
Peroxisome proliferator-activated receptor-gamma agonists inhibit the replication of respiratory syncytial virus (RSV) in human lung epithelial cells. |
2006 |
Virology |
pmid:16616290
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Cheng K et al. |
Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16617107
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Sheddan NA and Mulzer J |
Cross metathesis as a general strategy for the synthesis of prostacyclin and prostaglandin analogues. |
2006 |
Org. Lett. |
pmid:16805562
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Chiang PC et al. |
Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells. |
2006 |
Eur. J. Pharmacol. |
pmid:16806159
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Ogburn KD et al. |
Prostaglandin J2 reduces catechol-O-methyltransferase activity and enhances dopamine toxicity in neuronal cells. |
2006 |
Neurobiol. Dis. |
pmid:16406650
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Effects of indomethacin and dexamethasone on mechanical scratching-induced cutaneous barrier disruption in mice. |
2006 |
Exp. Dermatol. |
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15d-prostaglandin J2 protects brain from ischemia-reperfusion injury. |
2006 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:16385084
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Ding J et al. |
Cyclooxygenase isozymes are expressed in human myeloma cells but not involved in anti-proliferative effect of cyclooxygenase inhibitors. |
2006 |
Mol. Carcinog. |
pmid:16385588
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Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species. |
2006 |
Am. J. Physiol. Heart Circ. Physiol. |
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Neuronal expression of peroxisome proliferator-activated receptor-gamma (PPARgamma) and 15d-prostaglandin J2--mediated protection of brain after experimental cerebral ischemia in rat. |
2006 |
Brain Res. |
pmid:16725118
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Lee S et al. |
Rosiglitazone ameliorates cisplatin-induced renal injury in mice. |
2006 |
Nephrol. Dial. Transplant. |
pmid:16728429
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Rajasingh J and Bright JJ |
15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells. |
2006 |
Exp. Cell Res. |
pmid:16737695
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Wang Z et al. |
Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells. |
2006 |
J. Biol. Chem. |
pmid:16737963
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Yasugi E et al. |
Peroxisome proliferator-activated receptor gamma ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells. |
2006 |
Dev. Growth Differ. |
pmid:16573735
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Peroxisome proliferator-activated receptors and acute lung injury. |
2006 |
Curr Opin Pharmacol |
pmid:16580256
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Brannan JD et al. |
Inhibition of mast cell PGD2 release protects against mannitol-induced airway narrowing. |
2006 |
Eur. Respir. J. |
pmid:16707393
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Suzuki T et al. |
Peroxisome proliferator-activated receptor gamma in human breast carcinoma: a modulator of estrogenic actions. |
2006 |
Endocr. Relat. Cancer |
pmid:16601291
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Bellows CF et al. |
Modulation of macrophage nitric oxide production by prostaglandin D2. |
2006 |
J. Surg. Res. |
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Helliwell RJ et al. |
Gestational age-dependent up-regulation of prostaglandin D synthase (PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta. |
2006 |
J. Clin. Endocrinol. Metab. |
pmid:16291703
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Stamatakis K et al. |
Identification of novel protein targets for modification by 15-deoxy-Delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton. |
2006 |
J. Am. Soc. Nephrol. |
pmid:16291835
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Induction of the permeability transition and cytochrome c release by 15-deoxy-Delta12,14-prostaglandin J2 in mitochondria. |
2006 |
Biochem. J. |
pmid:16268779
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Differentiation and growth inhibition mediated via the RXR:PPARgamma heterodimer in colon cancer. |
2006 |
Cancer Lett. |
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[The role of peroxisome proliferator-activated receptor gamma in proliferation of cardiac non myocytes]. |
2006 |
Zhongguo Ying Yong Sheng Li Xue Za Zhi |
pmid:21162229
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Garg TK and Chang JY |
Methylmercury causes oxidative stress and cytotoxicity in microglia: attenuation by 15-deoxy-delta 12, 14-prostaglandin J2. |
2006 |
J. Neuroimmunol. |
pmid:16225932
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Shiraki T et al. |
Spectroscopic analyses of the binding kinetics of 15d-PGJ2 to the PPARgamma ligand-binding domain by multi-wavelength global fitting. |
2006 |
Biochem. J. |
pmid:16236024
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[Stress and inflammatory bowell disease (I.B.D). Therapeutic strategies]. |
2006 |
An R Acad Nac Med (Madr) |
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15-deoxy-(Delta12,14)-prostaglandin J2 (15d-PGJ2) induces cell death through caspase-independent mechanism in A172 human glioma cells. |
2006 |
Neurochem. Res. |
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Maciejewski-Lenoir D et al. |
Langerhans cells release prostaglandin D2 in response to nicotinic acid. |
2006 |
J. Invest. Dermatol. |
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GW627368X ((N-{2-[4-(4,9-diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)phenyl]acetyl} benzene sulphonamide): a novel, potent and selective prostanoid EP4 receptor antagonist. |
2006 |
Br. J. Pharmacol. |
pmid:16604093
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Millán O et al. |
Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis. |
2006 |
Carcinogenesis |
pmid:16113051
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Tanaka H et al. |
Polymer-assisted solution-phase synthesis and neurite-outgrowth-promoting activity of 15-deoxy-delta(12,14)-PGJ2 derivatives. |
2006 |
Chem Asian J |
pmid:17441107
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Gulliksson M et al. |
Release of prostaglandin D2 and leukotriene C4 in response to hyperosmolar stimulation of mast cells. |
2006 |
Allergy |
pmid:17073880
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Phulwani NK et al. |
15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway. |
2006 |
J. Neurochem. |
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Kim EH et al. |
Upregulation of VEGF by 15-deoxy-Delta12,14-prostaglandin J2 via heme oxygenase-1 and ERK1/2 signaling in MCF-7 cells. |
2006 |
Ann. N. Y. Acad. Sci. |
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Aquila S et al. |
Peroxisome proliferator-activated receptor (PPAR)gamma is expressed by human spermatozoa: its potential role on the sperm physiology. |
2006 |
J. Cell. Physiol. |
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Addition of electrophilic lipids to actin alters filament structure. |
2006 |
Biochem. Biophys. Res. Commun. |
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Effect of 15d-PGJ2 on the expression of CD40 and RANTES induced by IFN-gamma and TNF-alpha on renal tubular epithelial cells (HK-2). |
2006 |
Am. J. Nephrol. |
pmid:16864989
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Schratl P et al. |
Hierarchy of eosinophil chemoattractants: role of p38 mitogen-activated protein kinase. |
2006 |
Eur. J. Immunol. |
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Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway. |
2006 |
Mol. Pharmacol. |
pmid:16908599
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Egan K and FitzGerald GA |
Eicosanoids and the vascular endothelium. |
2006 |
Handb Exp Pharmacol |
pmid:16999220
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Sugimoto M et al. |
Time course changes of scratching counts, dermatitis symptoms, and levels of cutaneous prostaglandins in NC/Nga mice. |
2006 |
Exp. Dermatol. |
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Feldon SE et al. |
Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytes. |
2006 |
Am. J. Pathol. |
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Prostaglandin D2 and J2-series (PGJ2, Delta12-PGJ2) prostaglandins stimulate IL-6 and MCP-1, but inhibit leptin, expression and secretion by 3T3-L1 adipocytes. |
2006 |
Pflugers Arch. |
pmid:16924534
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Peroxisome proliferator-activated receptor-gamma ligands inhibit proliferation and induce apoptosis in mantle cell lymphoma. |
2006 |
Anticancer Drugs |
pmid:16926626
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Masuda H et al. |
15-deoxy-Delta12,14-prostaglandin J2 attenuates development of cyclophosphamide-induced cystitis in rats. |
2006 |
Urology |
pmid:16461118
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Anti-asthmatic activity of an ethanol extract from Saururus chinensis. |
2006 |
Biol. Pharm. Bull. |
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Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. |
2006 |
J. Lipid Res. |
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The in vitro real-time oscillation monitoring system identifies potential entrainment factors for circadian clocks. |
2006 |
BMC Mol. Biol. |
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Damrongsri D et al. |
Effects of Delta12-prostaglandin J2 on bone regeneration and growth factor expression in rats. |
2006 |
Clin Oral Implants Res |
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Mesquita-Santos FP et al. |
Cutting edge: prostaglandin D2 enhances leukotriene C4 synthesis by eosinophils during allergic inflammation: synergistic in vivo role of endogenous eotaxin. |
2006 |
J. Immunol. |
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The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model. |
2006 |
Br. J. Pharmacol. |
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Kang HY et al. |
Peroxisome proliferator-activated receptors-gamma activator, ciglitazone, inhibits human melanocyte growth through induction of apoptosis. |
2006 |
Arch. Dermatol. Res. |
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15-deoxy-Delta12,14-prostaglandin J2 inhibits the expression of microsomal prostaglandin E synthase type 2 in colon cancer cells. |
2006 |
J. Lipid Res. |
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Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice. |
2006 |
Arterioscler. Thromb. Vasc. Biol. |
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The peroxisome proliferator-activated receptor gamma (PPARgamma) ligands 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms. |
2006 |
J. Immunol. |
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