| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cystitis, Interstitial | D018856 | 2 associated lipids |
| Asthma, Aspirin-Induced | D055963 | 2 associated lipids |
| Optic Neuropathy, Ischemic | D018917 | 2 associated lipids |
| Idiopathic Pulmonary Fibrosis | D054990 | 4 associated lipids |
| Graves Ophthalmopathy | D049970 | 3 associated lipids |
| Leukemia, B-Cell | D015448 | 3 associated lipids |
| Airway Remodeling | D056151 | 3 associated lipids |
| Pulmonary Aspergillosis | D055732 | 1 associated lipids |
| Decapitation | D049248 | 2 associated lipids |
PGD2
Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.
Cross Reference
Introduction
To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PGD2?
PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PGD2
PubChem Associated disorders and diseases
What pathways are associated with PGD2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PGD2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with PGD2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PGD2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with PGD2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PGD2?
Knock-out
Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).
Rodent Model
Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with PGD2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Madhu C et al. | Penetration of natural prostaglandins and their ester prodrugs and analogs across human ocular tissues in vitro. | 1998 | J Ocul Pharmacol Ther | pmid:9811228 |
| Arakida Y et al. | In vitro pharmacologic profile of YM158, a new dual antagonist for LTD4 and TXA2 receptors. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808690 |
| Ma H et al. | Estrogen-induced production of a peroxisome proliferator-activated receptor (PPAR) ligand in a PPARgamma-expressing tissue. | 1998 | J. Biol. Chem. | pmid:9804768 |
| Matsushita N et al. | Pharmacological studies on the novel antiallergic drug HQL-79: II. Elucidation of mechanisms for antiallergic and antiasthmatic effects. | 1998 | Jpn. J. Pharmacol. | pmid:9804057 |
| Huszár E et al. | Elevated circulating adenosine level potentiates antigen-induced immediate bronchospasm and bronchoconstrictor mediator release in sensitized guinea pigs. | 1998 | J. Allergy Clin. Immunol. | pmid:9802380 |
| Tada K et al. | Induction of cyclooxygenase-2 by secretory phospholipases A2 in nerve growth factor-stimulated rat serosal mast cells is facilitated by interaction with fibroblasts and mediated by a mechanism independent of their enzymatic functions. | 1998 | J. Immunol. | pmid:9794438 |
| Ohtani-Fujita N et al. | p53-Independent activation of the gadd45 promoter by Delta12-prostaglandin J2. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9792828 |
| Szczeklik A et al. | Salmeterol prevents aspirin-induced attacks of asthma and interferes with eicosanoid metabolism. | 1998 | Am. J. Respir. Crit. Care Med. | pmid:9769277 |
| Crider JY et al. | Use of a semi-automated, robotic radioimmunoassay to measure cAMP generated by activation of DP-, EP2-, and IP-prostaglandin receptors in human ocular and other cell types. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9758211 |
| Kilunga Kubata B et al. | Plasmodium falciparum produces prostaglandins that are pyrogenic, somnogenic, and immunosuppressive substances in humans. | 1998 | J. Exp. Med. | pmid:9743538 |