PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Cystitis, Interstitial D018856 2 associated lipids
Asthma, Aspirin-Induced D055963 2 associated lipids
Optic Neuropathy, Ischemic D018917 2 associated lipids
Idiopathic Pulmonary Fibrosis D054990 4 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Pulmonary Aspergillosis D055732 1 associated lipids
Decapitation D049248 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PGD2

Download all related citations
Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Toda N Different responsiveness of a variety of isolated dog arteries to prostaglandin D2. 1982 Prostaglandins pmid:6950464
Watanabe T et al. Characterization of the biosynthetic pathway of prostaglandin D2 in human platelet-rich plasma. 1982 J. Biol. Chem. pmid:6816798
Kinoshita F et al. Suppressive effect of prostaglandin (PG)D2 on pulsatile luteinizing hormone release in conscious castrated rats. 1982 Endocrinology pmid:6951712
Ogino N et al. Phagocytic activity of cultured retinal pigment epithelial cells from chick embryo: inhibition by melatonin and cyclic AMP, and its reversal by taurine and cyclic GMP. 1983 Ophthalmic Res. pmid:6136017
Ruzicka T et al. Inhibition of rat mast cell arachidonic acid cyclooxygenase by dapsone. 1983 J. Allergy Clin. Immunol. pmid:6413566
Simmet T and Jaffe BM Inhibition of B-16 melanoma growth in vitro by prostaglandin D2. 1983 Prostaglandins pmid:6573723
Kondo K et al. Effects of intracerebroventricular administration of prostaglandin D2 and angiotensin II on blood pressure in conscious rats. 1983 Jpn Heart J pmid:6574266
Hensby CN et al. Prostaglandins in human skin disease. 1983 Br. J. Dermatol. pmid:6574787
Higashida H et al. Cytotoxic action of prostaglandin D2 on mouse neuroblastoma cells. 1983 Int. J. Cancer pmid:6574994
Carr BR et al. Prostaglandin secretion by the neocortex and fetal zones of the human fetal adrenal gland. 1983 J. Clin. Endocrinol. Metab. pmid:6313732