PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Translocation, Genetic D014178 20 associated lipids
Catalepsy D002375 30 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Leiomyoma D007889 8 associated lipids
Leukemia, T-Cell D015458 23 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Urticaria D014581 13 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
HIV Seropositivity D006679 15 associated lipids
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Chondrosarcoma D002813 9 associated lipids
Dirofilariasis D004184 3 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hypothermia D007035 19 associated lipids
Retinopathy of Prematurity D012178 9 associated lipids
Parkinson Disease D010300 53 associated lipids
Down Syndrome D004314 18 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Headache D006261 4 associated lipids
Drug Eruptions D003875 30 associated lipids
Folliculitis D005499 7 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Muscular Dystrophy, Animal D009137 5 associated lipids
Actinobacillus Infections D000189 4 associated lipids
Atherosclerosis D050197 85 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Cryptorchidism D003456 2 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Dehydration D003681 11 associated lipids
Encephalitis D004660 15 associated lipids
Cholangitis D002761 3 associated lipids
Meningoencephalitis D008590 4 associated lipids
Thyroiditis, Autoimmune D013967 9 associated lipids
Weight Loss D015431 56 associated lipids
Endotoxemia D019446 27 associated lipids
Blister D001768 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Acute Lung Injury D055371 33 associated lipids
Vasculitis, Leukocytoclastic, Cutaneous D018366 5 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
Sleep Disorders, Circadian Rhythm D020178 3 associated lipids
Sneezing D012912 6 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Helicobacter Infections D016481 21 associated lipids
Coronary Restenosis D023903 10 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Lymphoma, T-Cell D016399 11 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Goiter D006042 4 associated lipids
Leukemia, Megakaryoblastic, Acute D007947 7 associated lipids
Angioedemas, Hereditary D054179 2 associated lipids
Thrombophilia D019851 6 associated lipids
HTLV-I Infections D015490 3 associated lipids
Nasal Obstruction D015508 4 associated lipids
Persistent Fetal Circulation Syndrome D010547 1 associated lipids
Zollinger-Ellison Syndrome D015043 1 associated lipids
Cryptococcosis D003453 3 associated lipids
Anal Gland Neoplasms D000694 1 associated lipids
Trigeminal Neuralgia D014277 1 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
Respiratory Sounds D012135 3 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Choroid Diseases D015862 2 associated lipids
Wounds, Stab D014951 3 associated lipids
Tauopathies D024801 6 associated lipids
Mastocytosis, Systemic D034721 1 associated lipids
Coronavirus Infections D018352 4 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Cystitis, Interstitial D018856 2 associated lipids
Asthma, Aspirin-Induced D055963 2 associated lipids
Optic Neuropathy, Ischemic D018917 2 associated lipids
Idiopathic Pulmonary Fibrosis D054990 4 associated lipids
Graves Ophthalmopathy D049970 3 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Airway Remodeling D056151 3 associated lipids
Pulmonary Aspergillosis D055732 1 associated lipids
Decapitation D049248 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PGD2

Download all related citations
Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
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