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Oxidized low-density lipoprotein and 15-deoxy-delta 12,14-PGJ2 increase mitochondrial complex I activity in endothelial cells. |
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PPARgamma ligands induce prostaglandin production in vascular smooth muscle cells: indomethacin acts as a peroxisome proliferator-activated receptor-gamma antagonist. |
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Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element. |
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PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes. |
2003 |
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Molecular characterization of human and rat organic anion transporter OATP-D. |
2003 |
Am. J. Physiol. Renal Physiol. |
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Arch. Biochem. Biophys. |
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Am. J. Physiol. Regul. Integr. Comp. Physiol. |
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Exp. Mol. Med. |
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Differential expression of c-fos and c-myc protooncogenes by estrogens, xenobiotics and other growth-stimulatory agents in primary rat hepatocytes. |
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Arch. Toxicol. |
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Am. J. Physiol. Regul. Integr. Comp. Physiol. |
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Cell Biochem. Biophys. |
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Invest. Ophthalmol. Vis. Sci. |
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An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro. |
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Mol. Pharmacol. |
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Gut |
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Biochemistry |
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PPARgamma ligands and ATRA inhibit the invasion of human breast cancer cells in vitro. |
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Breast Cancer Res. Treat. |
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The PPAR-gamma ligand 15-deoxy(delta12,14) prostaglandin J2 reduces the liver injury in endotoxic shock. |
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Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. |
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Br. J. Pharmacol. |
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Selective activation of PPARgamma inhibits pancreatic cancer invasion and decreases expression of tissue plasminogen activator. |
2003 |
Surgery |
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Arthritis Rheum. |
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Curr Drug Targets Inflamm Allergy |
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15d-PGJ2 inhibits cell growth and induces apoptosis of MCG-803 human gastric cancer cell line. |
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World J. Gastroenterol. |
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J. Immunol. |
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Eur. J. Immunol. |
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Hematopoietic prostaglandin D synthase is expressed in microglia in the developing postnatal mouse brain. |
2003 |
Glia |
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Breast Cancer Res. Treat. |
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The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras. |
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Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. |
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Biochemistry |
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15-deoxy-delta(12,14)-prostaglandin J2 inhibits IFN-gamma-induced galectin-9 expression in cultured human umbilical vein endothelial cells. |
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Activation of PPARgamma increases PTEN expression in pancreatic cancer cells. |
2003 |
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15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia. |
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15-Deoxy-Delta(12,14)-prostaglandin J2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-gamma-independent mechanism. |
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Biochem. Biophys. Res. Commun. |
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Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. |
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Am. J. Physiol. Lung Cell Mol. Physiol. |
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Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells. |
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Fertil. Steril. |
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15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils. |
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Prostaglandin J2 metabolites inhibit aromatase activity by redox-sensitive mechanisms: potential implications for breast cancer therapy. |
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Gene structure and functional properties of mouse CRTH2, a prostaglandin D2 receptor. |
2003 |
Biochem. Biophys. Res. Commun. |
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Hematopoietic prostaglandin D synthase. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
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The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12895600
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A novel PGD(2) receptor expressed in eosinophils. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12895601
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The DP receptor, allergic inflammation and asthma. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
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Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells. |
2003 Feb-Mar |
Placenta |
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The peroxisome proliferator-activated receptor-gamma ligand 15-deoxyDelta12,14 prostaglandin J2 reduces the organ injury in hemorrhagic shock. |
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Endogenous inhibitors of nuclear factor-kappaB, an opportunity for cancer control. |
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Cancer Res. |
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Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis. |
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Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2). |
2004 |
Biochemistry |
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Activated human dendritic cells express inducible cyclo-oxygenase and synthesize prostaglandin E2 but not prostaglandin D2. |
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Immunol. Cell Biol. |
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Peroxisome proliferator-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis associated with inhibition of self-sensitive T cells. |
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Monitoring mast cell activation by prostaglandin D2 in vivo. |
2004 |
Thorax |
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Plasma 9alpha,11beta-PGF2, a PGD2 metabolite, as a sensitive marker of mast cell activation by allergen in bronchial asthma. |
2004 |
Thorax |
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Stress protein activation by the cyclopentenone prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in human mesangial cells. |
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Kidney Int. |
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PPARgamma ligands attenuate mesangial contractile dysfunction in high glucose. |
2004 |
Kidney Int. |
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Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma. |
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Cancer Res. |
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The synthesis and effects of prostaglandins on the ovary of the crab Oziotelphusa senex senex. |
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Gen. Comp. Endocrinol. |
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Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells. |
2004 |
Biochem. Biophys. Res. Commun. |
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T-cell trafficking in asthma: lipid mediators grease the way. |
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p44/42(ERK1/2) MAPK and PLD activation by PGD2 preserves papillary phosphatidylcholine homeostasis. |
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Ciglitizone and 15d PGJ2 induce apoptosis in Jurkat and Raji cells. |
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Int. Immunopharmacol. |
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Ligands of peroxisome proliferator-activated receptor gamma inhibit lung cancer cell growth and induce apoptosis by stimulation of P21 expression. |
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Chest |
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Role of peroxisome proliferator-activated receptor-gamma in the protection afforded by 15-deoxydelta12,14 prostaglandin J2 against the multiple organ failure caused by endotoxin. |
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Crit. Care Med. |
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Resveratrol inhibits the release of mediators from bone marrow-derived mouse mast cells in vitro. |
2004 |
Planta Med. |
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Peroxisome proliferator-activated receptor gamma ligands induce growth inhibition and apoptosis of human B lymphocytic leukemia. |
2004 |
Leuk. Res. |
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Chondrogenesis of expanded adult human articular chondrocytes is enhanced by specific prostaglandins. |
2004 |
Rheumatology (Oxford) |
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