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Resident peritoneal macrophages and mast cells are important cellular sites of COX-1 and COX-2 activity during acute peritoneal inflammation. |
2009 Nov-Dec |
Arch. Immunol. Ther. Exp. (Warsz.) |
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Moreira V et al. |
Effects of Bothrops asper snake venom on the expression of cyclooxygenases and production of prostaglandins by peritoneal leukocytes in vivo, and by isolated neutrophils and macrophages in vitro. |
2009 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:19155166
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Hayden RE et al. |
Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2. |
2009 |
Leukemia |
pmid:18923439
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Csanky E et al. |
Lipid metabolite levels of prostaglandin D2 and eicosapentaenoic acid recovered from bronchoalveolar lavage fluid correlate with lung function of chronic obstructive pulmonary disease patients and controls. |
2009 |
Electrophoresis |
pmid:19294692
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Kase K et al. |
Inhibitory action of roxithromycin on histamine release and prostaglandin D2 production from beta-defensin 2-stimulated mast cells. |
2009 |
Int. J. Mol. Med. |
pmid:19212651
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Ricart KC et al. |
The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells. |
2009 |
Biochem. J. |
pmid:19161347
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Lee DR et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) induces mitochondrial-dependent apoptosis through inhibition of PKA/NF-kappaB in renal proximal epithelial cells. |
2009 |
Toxicology |
pmid:19167456
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Pirianov G et al. |
The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse. |
2009 |
Endocrinology |
pmid:18845626
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Tsuji T et al. |
Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen. |
2009 |
Neurochem. Res. |
pmid:18946735
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Waku T et al. |
Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids. |
2009 |
J. Mol. Biol. |
pmid:18977231
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Bruck R et al. |
Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor. |
2009 |
Dig. Dis. Sci. |
pmid:18594976
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O'Brien JJ et al. |
15-deoxy-Delta12,14 prostaglandin J2-induced heme oxygenase-1 in megakaryocytes regulates thrombopoiesis. |
2009 |
J. Thromb. Haemost. |
pmid:18983509
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Kalantari P et al. |
15-Deoxy-Delta12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification. |
2009 |
FASEB J. |
pmid:19299483
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Mohri I et al. |
Inhibition of prostaglandin D synthase suppresses muscular necrosis. |
2009 |
Am. J. Pathol. |
pmid:19359520
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Moriai M et al. |
Down-regulation of hTERT expression plays an important role in 15-deoxy-Delta12,14-prostaglandin J2-induced apoptosis in cancer cells. |
2009 |
Int. J. Oncol. |
pmid:19360348
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Boehme SA et al. |
Murine bone marrow-derived mast cells express chemoattractant receptor-homologous molecule expressed on T-helper class 2 cells (CRTh2). |
2009 |
Int. Immunol. |
pmid:19346259
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Iinuma K et al. |
Involvement of Propionibacterium acnes in the augmentation of lipogenesis in hamster sebaceous glands in vivo and in vitro. |
2009 |
J. Invest. Dermatol. |
pmid:19282842
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Boehme SA et al. |
A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation. |
2009 |
Int. Immunol. |
pmid:19066314
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Boehme SA et al. |
Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms. |
2009 |
Int. Immunol. |
pmid:19066315
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Ding Q et al. |
Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. |
2009 |
Endocrinology |
pmid:19074584
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Schröder R et al. |
The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation. |
2009 |
J. Biol. Chem. |
pmid:19010788
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Eichele K et al. |
R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. |
2009 |
Pharm. Res. |
pmid:19015962
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Gressner OA et al. |
Elevated concentrations of 15-deoxy-Delta12,14-prostaglandin J2 in chronic liver disease propose therapeutic trials with peroxisome proliferator activated receptor gamma-inducing drugs. |
2009 |
Liver Int. |
pmid:19018984
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Kobayashi M et al. |
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. |
2009 |
Mol. Cell. Biol. |
pmid:19001094
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Irikura D et al. |
Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase. |
2009 |
J. Biol. Chem. |
pmid:19131342
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Johansson S et al. |
CC16 inhibits the migration of eosinophils towards the formyl peptide fMLF but not towards PGD2. |
2009 |
Inflammation |
pmid:19132521
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Kim DH et al. |
15-Deoxy-Delta12,14-prostaglandin J2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS. |
2009 |
Carcinogenesis |
pmid:19136476
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Di Francesco L et al. |
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells. |
2009 |
Circ. Res. |
pmid:19122175
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Wang WM et al. |
PPAR-gamma agonists inhibit TGF-beta1-induced chemokine expression in human tubular epithelial cells. |
2009 |
Acta Pharmacol. Sin. |
pmid:19098936
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Tokudome S et al. |
Glucocorticoid protects rodent hearts from ischemia/reperfusion injury by activating lipocalin-type prostaglandin D synthase-derived PGD2 biosynthesis. |
2009 |
J. Clin. Invest. |
pmid:19451694
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Mickleborough TD et al. |
Eicosapentaenoic acid is more effective than docosahexaenoic acid in inhibiting proinflammatory mediator production and transcription from LPS-induced human asthmatic alveolar macrophage cells. |
2009 |
Clin Nutr |
pmid:19054597
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Arnaud LT et al. |
Proteasome-caspase-cathepsin sequence leading to tau pathology induced by prostaglandin J2 in neuronal cells. |
2009 |
J. Neurochem. |
pmid:19457109
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Olmos G et al. |
15-Deoxy-Delta(12,14)-prostaglandin-J(2) reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1alpha degradation. |
2009 |
Cell. Mol. Life Sci. |
pmid:19458911
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Brechbuhl HM et al. |
Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport. |
2009 |
Free Radic. Biol. Med. |
pmid:19520157
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Ramji DP |
Growth hormone-releasing peptides, CD36, and stimulation of cholesterol efflux: cyclooxygenase-2 is the link. |
2009 |
Cardiovasc. Res. |
pmid:19520704
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Xue L et al. |
Novel function of CRTH2 in preventing apoptosis of human Th2 cells through activation of the phosphatidylinositol 3-kinase pathway. |
2009 |
J. Immunol. |
pmid:19494281
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Intracellular protein phosphorylation in eosinophils and the functional relevance in cytokine production. |
2009 |
Int. Arch. Allergy Immunol. |
pmid:19494504
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Chiba T et al. |
15-Deoxy-Delta(12,14)-prostaglandin J2 induces IL-8 and GM-CSF in a human airway epithelial cell line (NCI-H292). |
2009 |
Int. Arch. Allergy Immunol. |
pmid:19494510
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Niki E |
Lipid peroxidation: physiological levels and dual biological effects. |
2009 |
Free Radic. Biol. Med. |
pmid:19500666
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Suk FM et al. |
15-deoxy-Delta(12,14)-prostaglandin J(2) inhibits fibrogenic response in human hepatoma cells. |
2009 |
Toxicol. Lett. |
pmid:19429239
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Kansanen E et al. |
Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2. |
2009 |
Free Radic. Biol. Med. |
pmid:19573595
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Cocca C et al. |
15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest. |
2009 |
Biochem. Pharmacol. |
pmid:19576185
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Thura M et al. |
GIF-0173 protects against cerebral infarction through DP1 receptor activation. |
2009 |
Exp. Neurol. |
pmid:19576888
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Bernardo A et al. |
Peroxisome proliferator-activated receptor-gamma agonists promote differentiation and antioxidant defenses of oligodendrocyte progenitor cells. |
2009 |
J. Neuropathol. Exp. Neurol. |
pmid:19535992
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Comabella M et al. |
Plasma levels of 15d-PGJ are not altered in multiple sclerosis. |
2009 |
Eur. J. Neurol. |
pmid:19538219
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Li H and Pauza CD |
Effects of 15-deoxy-delta12,14-prostaglandin J2 (15d-PGJ2) and rosiglitazone on human gammadelta2 T cells. |
2009 |
PLoS ONE |
pmid:19888466
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Landrier JF et al. |
Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism. |
2009 |
Endocrinology |
pmid:19833717
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Lauring B et al. |
Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. |
2009 |
J Clin Pharmacol |
pmid:19833861
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Hironaka A et al. |
15-Deoxy-Delta(12,14)-prostaglandin J(2) impairs the functions of histone acetyltransferases through their insolubilization in cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19799872
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Davies NJ et al. |
AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects. |
2009 |
Cancer Res. |
pmid:19487289
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