| MeSH term | MeSH ID | Detail |
|---|---|---|
| Carotid Artery Thrombosis | D002341 | 7 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Cell Transformation, Viral | D002472 | 26 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Cholangitis | D002761 | 3 associated lipids |
| Chondrosarcoma | D002813 | 9 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
PGD2
Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.
Cross Reference
Introduction
To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PGD2?
PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PGD2
PubChem Associated disorders and diseases
What pathways are associated with PGD2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PGD2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PGD2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PGD2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PGD2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PGD2?
Knock-out
Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).
Rodent Model
Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PGD2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Brus R et al. | Effect of prostaglandins on morphine-induced catalepsy in mice. | 1983 Sep-Dec | Acta Physiol Pol | pmid:6679984 |
| Diener M et al. | Characterization of the antisecretory action of prostaglandin D2 in the rat colon. | 1992 | Acta Physiol. Scand. | pmid:1502910 |
| Tamaoki J et al. | Prostaglandin D2 increases Cl secretion across canine tracheal epithelium through cyclo-oxygenase stimulation and cAMP production. | 1992 | Acta Physiol. Scand. | pmid:1323920 |
| Diener M and Gabato D | Thromboxane-like actions of prostaglandin D2 on the contractility of the rat colon in vitro. | 1994 | Acta Physiol. Scand. | pmid:8135127 |
| Alving K et al. | The possible role of prostaglandin D2 in the long-lasting airways vasodilatation induced by allergen in the sensitized pig. | 1991 | Acta Physiol. Scand. | pmid:1957709 |
| Eriksson LO et al. | Prostaglandin E2 binding sites in human renal tissue: characterization and localization by radioligand binding and autoradiography. | 1990 | Acta Physiol. Scand. | pmid:2173350 |
| Drummond WH | Persistent pulmonary hypertension of the neonate (persistent fetal circulation syndrome). | 1983 | Adv Pediatr | pmid:6424420 |
| Fukushima S et al. | Preparation and evaluation of o/w type emulsions containing antitumor prostaglandin. | 2000 | Adv. Drug Deliv. Rev. | pmid:11104898 |
| Hayaishi O | Tryptophan, oxygenase, and sleep. | 1996 | Adv. Exp. Med. Biol. | pmid:8906236 |
| Whittle BJ et al. | Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin E1 and D2 on platelets. | 1985 | Adv. Exp. Med. Biol. | pmid:2871707 |