Khan E and Abu-Amer Y |
Activation of peroxisome proliferator-activated receptor-gamma inhibits differentiation of preosteoblasts. |
2003 |
J. Lab. Clin. Med. |
pmid:12878983
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[Peroxisome proliferation-activated receptor-gamma ligands ameliorate autoimmune myocarditis associated with inhibition of T cell immunity]. |
2003 |
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pmid:14703419
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Ceaser EK et al. |
Oxidized low-density lipoprotein and 15-deoxy-delta 12,14-PGJ2 increase mitochondrial complex I activity in endothelial cells. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
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First enantioselective total synthesis of (8S,12R,15S)-prostaglandin J(2). |
2003 |
J. Org. Chem. |
pmid:12895084
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Genovese A et al. |
Protein Fv produced during viral hepatitis is an endogenous immunoglobulin superantigen activating human heart mast cells. |
2003 |
Int. Arch. Allergy Immunol. |
pmid:14707465
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Bishop-Bailey D and Warner TD |
PPARgamma ligands induce prostaglandin production in vascular smooth muscle cells: indomethacin acts as a peroxisome proliferator-activated receptor-gamma antagonist. |
2003 |
FASEB J. |
pmid:12897060
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Souza SC et al. |
TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes. |
2003 |
J. Cell. Biochem. |
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Prostaglandins of J series control heme oxygenase expression: potential significance in modulating neuroinflammation. |
2003 |
Ann. N. Y. Acad. Sci. |
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Pestel S et al. |
Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. |
2003 |
Biochem. Pharmacol. |
pmid:12906929
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Pritts EA et al. |
Peroxisome proliferator-activated receptor-gamma ligand inhibition of RANTES production by human endometriotic stromal cells is mediated through an upstream promoter element. |
2003 |
Fertil. Steril. |
pmid:12909507
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Nencioni A et al. |
Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling. |
2003 |
J. Immunol. |
pmid:14607914
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15-Deoxy-delta12,14-prostaglandin J2, a ligand for peroxisome proliferators-activated receptor-gamma, induces apoptosis in human hepatoma cells. |
2003 |
Liver Int. |
pmid:14986820
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Hu VY et al. |
COX-2 and prostanoid expression in micturition pathways after cyclophosphamide-induced cystitis in the rat. |
2003 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:12388444
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Kim BE et al. |
Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2. |
2003 |
Exp. Mol. Med. |
pmid:14508070
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Hashimoto K et al. |
The PPARgamma ligand, 15d-PGJ2, attenuates the severity of cerulein-induced acute pancreatitis. |
2003 |
Pancreas |
pmid:12826907
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Montuschi P et al. |
Exhaled leukotrienes and prostaglandins in COPD. |
2003 |
Thorax |
pmid:12832671
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Taba Y et al. |
15-deoxy-delta 12,14-prostaglandin J2 and laminar fluid shear stress stabilize c-IAP1 in vascular endothelial cells. |
2003 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:12623786
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Imaizumi T et al. |
15-Deoxy-delta 12,14-prostaglandin J2 inhibits the expression of granulocyte-macrophage colony-stimulating factor in endothelial cells stimulated with lipopolysaccharide. |
2003 |
Prostaglandins Other Lipid Mediat. |
pmid:14518569
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Lee CH and Edwards AM |
Differential expression of c-fos and c-myc protooncogenes by estrogens, xenobiotics and other growth-stimulatory agents in primary rat hepatocytes. |
2003 |
Arch. Toxicol. |
pmid:12632255
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Yoshimura R et al. |
The effect of peroxisome proliferator-activated receptor-gamma ligand on urological cancer cells. |
2003 |
Int. J. Mol. Med. |
pmid:14612958
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Jelson GS et al. |
Modulation of guinea pig intrinsic cardiac neurons by prostaglandins. |
2003 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
pmid:12791585
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Okano H et al. |
The PPARgamma ligand, 15-Deoxy-Delta12,14-PGJ2, regulates apoptosis-related protein expression in cholangio cell carcinoma cells. |
2003 |
Int. J. Mol. Med. |
pmid:14612959
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Rehan V and Torday J |
Hyperoxia augments pulmonary lipofibroblast-to-myofibroblast transdifferentiation. |
2003 |
Cell Biochem. Biophys. |
pmid:12794266
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Aoun P et al. |
Role of PPAR-gamma ligands in neuroprotection against glutamate-induced cytotoxicity in retinal ganglion cells. |
2003 |
Invest. Ophthalmol. Vis. Sci. |
pmid:12824244
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Ajmone-Cat MA et al. |
Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis. |
2003 |
J. Neurochem. |
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Sugimoto H et al. |
An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12649388
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Chung SW et al. |
Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor. |
2003 |
Mol. Pharmacol. |
pmid:14573767
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[Sleep substances]. |
2003 |
No To Shinkei |
pmid:12649899
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15-Deoxy-Delta(12,14)-prostaglandin J2 induces apoptosis through activation of the CHOP gene in HeLa cells. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14575689
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Effects of peroxisome proliferator-activated receptor gamma ligands ciglitazone and 15-deoxy-delta 12,14-prostaglandin J2 on rat cultured cerebellar granule neuronal viability. |
2003 |
J. Neurosci. Res. |
pmid:12774315
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Zamuner SR et al. |
Cyclooxygenase 2 mediates post-inflammatory colonic secretory and barrier dysfunction. |
2003 |
Gut |
pmid:14633948
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Armoni M et al. |
Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect. |
2003 |
J. Biol. Chem. |
pmid:12777391
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An endogenous electrophile that modulates the regulatory mechanism of protein turnover: inhibitory effects of 15-deoxy-Delta 12,14-prostaglandin J2 on proteasome. |
2003 |
Biochemistry |
pmid:14636064
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Liu H et al. |
PPARgamma ligands and ATRA inhibit the invasion of human breast cancer cells in vitro. |
2003 |
Breast Cancer Res. Treat. |
pmid:12779083
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Villegas I et al. |
A new flavonoid derivative, dosmalfate, attenuates the development of dextran sulphate sodium-induced colitis in mice. |
2003 |
Int. Immunopharmacol. |
pmid:14636824
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Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 1. Bicyclo[2.2.1]heptane derivatives. |
2003 |
J. Med. Chem. |
pmid:12773047
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Inoue K et al. |
Effect of 15-deoxy-delta 12,14-prostaglandin J2 on acute lung injury induced by lipopolysaccharide in mice. |
2003 |
Eur. J. Pharmacol. |
pmid:14642794
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Mitsumori S et al. |
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane derivatives. |
2003 |
J. Med. Chem. |
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Activation of nuclear receptors by prostaglandins. |
2003 |
Thromb. Res. |
pmid:14592554
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Yagami T et al. |
Novel binding sites of 15-deoxy-Delta12,14-prostaglandin J2 in plasma membranes from primary rat cortical neurons. |
2003 |
Exp. Cell Res. |
pmid:14597421
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15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide. |
2003 |
J. Biol. Chem. |
pmid:14557273
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Komar CM and Curry TE |
Inverse relationship between the expression of messenger ribonucleic acid for peroxisome proliferator-activated receptor gamma and P450 side chain cleavage in the rat ovary. |
2003 |
Biol. Reprod. |
pmid:12700202
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Bochenek G et al. |
A controlled study of 9alpha,11beta-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge. |
2003 |
J. Allergy Clin. Immunol. |
pmid:12704352
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Castaño E and Gil J |
15-deoxy-delta12,14 prostaglandin J2 synergizes with phorbol ester to induce proliferation in Swiss 3T3 cells independently of peroxisome proliferator-activated receptor gamma and PGD2 receptors. |
2003 |
J. Cell. Physiol. |
pmid:12704651
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Retrovirally introduced prostaglandin D2 synthase suppresses lung injury induced by bleomycin. |
2003 |
Am. J. Respir. Cell Mol. Biol. |
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Effect of 15-deoxy-delta12,14-prostaglandin J2 on IL-1beta-induced expression of epithelial neutrophil-activating protein-78 in human endothelial cells. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:14580366
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Cippitelli M et al. |
The cyclopentenone-type prostaglandin 15-deoxy-delta 12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with promoter activation via peroxisome proliferator-activated receptor-gamma-independent mechanisms. |
2003 |
J. Immunol. |
pmid:12707336
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Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis. |
2003 |
J. Immunol. |
pmid:12707356
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Activation of peroxisome proliferator-activated receptor alpha in human endothelial cells increases plasminogen activator inhibitor type-1 expression. |
2003 |
Chin. Med. J. |
pmid:12667383
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Prostaglandin D2 inhibits the production of interleukin-12 in murine dendritic cells through multiple signaling pathways. |
2003 |
Eur. J. Immunol. |
pmid:12672054
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Hematopoietic prostaglandin D synthase is expressed in microglia in the developing postnatal mouse brain. |
2003 |
Glia |
pmid:12673832
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Possible involvement of small oligomers of amyloid-beta peptides in 15-deoxy-delta 12,14 prostaglandin J2-sensitive microglial activation. |
2003 |
J. Pharmacol. Sci. |
pmid:12719662
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Involvement of c-jun N-terminal kinase activation in 15-deoxy-delta12,14-prostaglandin J2-and prostaglandin A1-induced apoptosis in AGS gastric epithelial cells. |
2003 |
Mol. Carcinog. |
pmid:12720296
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Expression and molecular pharmacology of the mouse CRTH2 receptor. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12721327
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The antiproliferative effects of PPARgamma ligands in normal human mammary epithelial cells. |
2003 |
Breast Cancer Res. Treat. |
pmid:12725418
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The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12684535
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Paumi CM et al. |
Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. |
2003 |
Biochemistry |
pmid:12731885
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Cuzzocrea S et al. |
The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat. |
2003 |
Br. J. Pharmacol. |
pmid:12598422
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Castrillo A et al. |
Potentiation of protein kinase C zeta activity by 15-deoxy-delta(12,14)-prostaglandin J(2) induces an imbalance between mitogen-activated protein kinases and NF-kappa B that promotes apoptosis in macrophages. |
2003 |
Mol. Cell. Biol. |
pmid:12556480
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Farrow B and Evers BM |
Activation of PPARgamma increases PTEN expression in pancreatic cancer cells. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12535639
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Park EJ et al. |
15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia. |
2003 |
J. Biol. Chem. |
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15-Deoxy-Delta(12,14)-prostaglandin J2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-gamma-independent mechanism. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12604364
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Jung KM et al. |
Activation of p38 mitogen-activated protein kinase and activator protein-1 during the promotion of neurite extension of PC-12 cells by 15-deoxy-delta12,14-prostaglandin J2. |
2003 |
Mol. Pharmacol. |
pmid:12606768
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Abe M et al. |
GATA-6 is involved in PPARgamma-mediated activation of differentiated phenotype in human vascular smooth muscle cells. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12615657
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Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. |
2003 |
Cancer Res. |
pmid:12615709
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Kajekar R et al. |
Role of cyclooxygenase activation and prostaglandins in antigen-induced excitability changes of bronchial parasympathetic ganglia neurons. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12618420
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Wanichkul T et al. |
Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells. |
2003 |
Fertil. Steril. |
pmid:12620489
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Monneret G et al. |
15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils. |
2003 |
J. Pharmacol. Exp. Ther. |
pmid:12490611
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Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors. |
2003 |
J. Immunol. |
pmid:12517972
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Identification by site-directed mutagenesis of amino acids contributing to ligand-binding specificity or signal transduction properties of the human FP prostanoid receptor. |
2003 |
Biochem. J. |
pmid:12519077
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Hirano A et al. |
Arachidonic acid-induced channel- and carrier-type ion transport across planar bilayer lipid membranes. |
2003 |
Anal Sci |
pmid:12608744
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Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells. |
2003 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12524224
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Gene structure and functional properties of mouse CRTH2, a prostaglandin D2 receptor. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12878180
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Zhang X et al. |
Unexpected sensitivity of synthetic Renilla luciferase control vectors to treatment with a cyclopentenone prostaglandin. |
2003 |
BioTechniques |
pmid:14682047
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Kanaoka Y and Urade Y |
Hematopoietic prostaglandin D synthase. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12895599
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Nagata K and Hirai H |
The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12895600
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Powell WS |
A novel PGD(2) receptor expressed in eosinophils. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12895601
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Kabashima K and Narumiya S |
The DP receptor, allergic inflammation and asthma. |
2003 Aug-Sep |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12895602
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Moore RM et al. |
Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells. |
2003 Feb-Mar |
Placenta |
pmid:12566244
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Human multiple myeloma cells express peroxisome proliferator-activated receptor gamma and undergo apoptosis upon exposure to PPARgamma ligands. |
2004 |
Clin. Immunol. |
pmid:15451478
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Endogenous inhibitors of nuclear factor-kappaB, an opportunity for cancer control. |
2004 |
Cancer Res. |
pmid:15548674
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Inoue K et al. |
Effects of 15-deoxy-delta12,14-prostaglandin J2 on the cyclooxygenase-2 expression in the murine lung in the presence of lipopolysaccharide. |
2004 |
Arzneimittelforschung |
pmid:15612612
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Mitsumori S |
Recent progress in work on PGD2 antagonists for drugs targeting allergic diseases. |
2004 |
Curr. Pharm. Des. |
pmid:15579050
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Cheng S et al. |
Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. |
2004 |
J. Biol. Chem. |
pmid:15023995
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15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes. |
2004 |
J. Biol. Chem. |
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The human heart as a shock organ in anaphylaxis. |
2004 |
Novartis Found. Symp. |
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A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes. |
2004 |
Mol. Cancer Ther. |
pmid:15026545
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Hashimoto K et al. |
Activation and role of MAP kinases in 15d-PGJ2-induced apoptosis in the human pancreatic cancer cell line MIA PaCa-2. |
2004 |
Pancreas |
pmid:15028947
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Badawi AF et al. |
Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma. |
2004 |
Cancer Res. |
pmid:14871855
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Asada K et al. |
Antiinflammatory roles of peroxisome proliferator-activated receptor gamma in human alveolar macrophages. |
2004 |
Am. J. Respir. Crit. Care Med. |
pmid:14563653
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Boyault S et al. |
15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-1beta-induced IKK enzymatic activity and IkappaBalpha degradation in rat chondrocytes through a PPARgamma-independent pathway. |
2004 |
FEBS Lett. |
pmid:15304320
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Ichiki T et al. |
15-Deoxy-Delta12,14-prostaglandin J2 and thiazolidinediones transactivate epidermal growth factor and platelet-derived growth factor receptors in vascular smooth muscle cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15369766
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Schlezinger JJ et al. |
Environmental and endogenous peroxisome proliferator-activated receptor gamma agonists induce bone marrow B cell growth arrest and apoptosis: interactions between mono(2-ethylhexyl)phthalate, 9-cis-retinoic acid, and 15-deoxy-Delta12,14-prostaglandin J2. |
2004 |
J. Immunol. |
pmid:15322177
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15-deoxy-Delta12,14-prostaglandin J2 inhibits IFN-inducible protein 10/CXC chemokine ligand 10 expression in human microglia: mechanisms and implications. |
2004 |
J. Immunol. |
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Cheng J et al. |
Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15325252
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Chana RS et al. |
Differential effects of peroxisome proliferator activated receptor-gamma (PPAR gamma) ligands in proximal tubular cells: thiazolidinediones are partial PPAR gamma agonists. |
2004 |
Kidney Int. |
pmid:15149321
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Garg TK and Chang JY |
15-deoxy-delta 12, 14-Prostaglandin J2 prevents reactive oxygen species generation and mitochondrial membrane depolarization induced by oxidative stress. |
2004 |
BMC Pharmacol. |
pmid:15149553
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Park EY et al. |
Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-gamma and retinoid X receptor heterodimer. |
2004 |
Cancer Res. |
pmid:15150131
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Akbiyik F et al. |
Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. |
2004 |
Blood |
pmid:15130939
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Han S et al. |
Ligands of peroxisome proliferator-activated receptor gamma inhibit lung cancer cell growth and induce apoptosis by stimulation of P21 expression. |
2004 |
Chest |
pmid:15136464
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