Wang P et al. |
The antagonistic actions of endogenous interleukin-1β and 15-deoxy-Δ12,14-prostaglandin J2 regulate the temporal synthesis of matrix metalloproteinase-9 in sheared chondrocytes. |
2012 |
J. Biol. Chem. |
pmid:22829602
|
Casteleijn E et al. |
Endotoxin stimulates glycogenolysis in the liver by means of intercellular communication. |
1988 |
J. Biol. Chem. |
pmid:3284878
|
Kumar AP et al. |
Peroxisome proliferator-activated receptor gamma ligands regulate myeloperoxidase expression in macrophages by an estrogen-dependent mechanism involving the -463GA promoter polymorphism. |
2004 |
J. Biol. Chem. |
pmid:14668325
|
Böhm E et al. |
11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. |
2004 |
J. Biol. Chem. |
pmid:14668348
|
Tokumoto H et al. |
An NADP-linked 15-hydroxyprostaglandin dehydrogenase specific for prostaglandin D2 from swine brain. |
1982 |
J. Biol. Chem. |
pmid:6958674
|
Hayaishi O |
Sleep-wake regulation by prostaglandins D2 and E2. |
1988 |
J. Biol. Chem. |
pmid:3049580
|
Kuiper J et al. |
Induction of ornithine decarboxylase in rat liver by phorbol ester is mediated by prostanoids from Kupffer cells. |
1989 |
J. Biol. Chem. |
pmid:2708347
|
Nelson SM et al. |
Selenoprotein Expression in Macrophages Is Critical for Optimal Clearance of Parasitic Helminth Nippostrongylus brasiliensis. |
2016 |
J. Biol. Chem. |
pmid:26644468
|
Shibata T et al. |
15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes. |
2002 |
J. Biol. Chem. |
pmid:11786541
|
Mathurin K et al. |
An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production. |
2011 |
J. Biol. Chem. |
pmid:21112970
|
Urade Y et al. |
Purification and characterization of rat brain prostaglandin D synthetase. |
1985 |
J. Biol. Chem. |
pmid:3930495
|
Fournier T et al. |
Tumor necrosis factor-alpha inversely regulates prostaglandin D2 and prostaglandin E2 production in murine macrophages. Synergistic action of cyclic AMP on cyclooxygenase-2 expression and prostaglandin E2 synthesis. |
1997 |
J. Biol. Chem. |
pmid:9388257
|
Takeda K et al. |
15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells. |
2001 |
J. Biol. Chem. |
pmid:11687581
|
Bingham CO et al. |
A heparin-sensitive phospholipase A2 and prostaglandin endoperoxide synthase-2 are functionally linked in the delayed phase of prostaglandin D2 generation in mouse bone marrow-derived mast cells. |
1996 |
J. Biol. Chem. |
pmid:8824228
|
Masamune A et al. |
Ligands of peroxisome proliferator-activated receptor-gamma block activation of pancreatic stellate cells. |
2002 |
J. Biol. Chem. |
pmid:11606585
|
Inoue H et al. |
Feedback control of cyclooxygenase-2 expression through PPARgamma. |
2000 |
J. Biol. Chem. |
pmid:10827178
|
Ogburn KD and Figueiredo-Pereira ME |
Cytoskeleton/endoplasmic reticulum collapse induced by prostaglandin J2 parallels centrosomal deposition of ubiquitinated protein aggregates. |
2006 |
J. Biol. Chem. |
pmid:16774923
|
Reddy ST et al. |
Analysis of the secretory phospholipase A2 that mediates prostaglandin production in mast cells. |
1997 |
J. Biol. Chem. |
pmid:9153207
|
Relic B et al. |
Peroxisome proliferator-activated receptor-gamma1 is dephosphorylated and degraded during BAY 11-7085-induced synovial fibroblast apoptosis. |
2006 |
J. Biol. Chem. |
pmid:16766531
|
Odani N et al. |
Regulation of BiP gene expression by cyclopentenone prostaglandins through unfolded protein response element. |
1996 |
J. Biol. Chem. |
pmid:8663202
|
Jiang JG et al. |
Peroxisome proliferator-activated receptor gamma-mediated transcriptional up-regulation of the hepatocyte growth factor gene promoter via a novel composite cis-acting element. |
2001 |
J. Biol. Chem. |
pmid:11292834
|
Watanabe T et al. |
Characterization of the biosynthetic pathway of prostaglandin D2 in human platelet-rich plasma. |
1982 |
J. Biol. Chem. |
pmid:6816798
|
Cheng S et al. |
Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. |
2004 |
J. Biol. Chem. |
pmid:15023995
|
Kawamoto Y et al. |
Cyclopentenone prostaglandins as potential inducers of phase II detoxification enzymes. 15-deoxy-delta(12,14)-prostaglandin j2-induced expression of glutathione S-transferases. |
2000 |
J. Biol. Chem. |
pmid:10753940
|
Alvarez-Maqueda M et al. |
15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes. |
2004 |
J. Biol. Chem. |
pmid:15024026
|
Liu H et al. |
Regulation of the surface expression of the platelet-activating factor receptor in IC-21 peritoneal macrophages. Effects of lipopolysaccharide. |
1992 |
J. Biol. Chem. |
pmid:1328211
|
Wang Z et al. |
Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells. |
2006 |
J. Biol. Chem. |
pmid:16737963
|
Reddy ST and Herschman HR |
Prostaglandin synthase-1 and prostaglandin synthase-2 are coupled to distinct phospholipases for the generation of prostaglandin D2 in activated mast cells. |
1997 |
J. Biol. Chem. |
pmid:9013559
|
Relic B et al. |
15-deoxy-delta12,14-prostaglandin J2 inhibits Bay 11-7085-induced sustained extracellular signal-regulated kinase phosphorylation and apoptosis in human articular chondrocytes and synovial fibroblasts. |
2004 |
J. Biol. Chem. |
pmid:15004016
|
Degousee N et al. |
Group V phospholipase A2 in bone marrow-derived myeloid cells and bronchial epithelial cells promotes bacterial clearance after Escherichia coli pneumonia. |
2011 |
J. Biol. Chem. |
pmid:21849511
|
Miyahara T et al. |
Peroxisome proliferator-activated receptors and hepatic stellate cell activation. |
2000 |
J. Biol. Chem. |
pmid:10969082
|
Kuehn HS et al. |
Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release. |
2011 |
J. Biol. Chem. |
pmid:20980255
|
Sakamoto H et al. |
Involvement of phospholipid hydroperoxide glutathione peroxidase in the modulation of prostaglandin D2 synthesis. |
2000 |
J. Biol. Chem. |
pmid:11010961
|
Kozak KR et al. |
Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2. |
2000 |
J. Biol. Chem. |
pmid:10931854
|
He P et al. |
Oxidative stress suppresses cysteinyl leukotriene generation by mouse bone marrow-derived mast cells. |
2011 |
J. Biol. Chem. |
pmid:21233206
|
Choi YH et al. |
The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling. |
2011 |
J. Biol. Chem. |
pmid:21832046
|
Nie M et al. |
Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists. |
2005 |
J. Biol. Chem. |
pmid:15531761
|
Werman A et al. |
Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgamma1 and -2 isoforms and influence of insulin. |
1997 |
J. Biol. Chem. |
pmid:9242701
|
Paik JH et al. |
Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways. |
2000 |
J. Biol. Chem. |
pmid:10866999
|
Shimizu T et al. |
Specific binding of prostaglandin D2 to rat brain synaptic membrane. Occurrence, properties, and distribution. |
1982 |
J. Biol. Chem. |
pmid:6292197
|
Eling TE et al. |
Oxidation of glutathione to its thiyl free radical metabolite by prostaglandin H synthase. A potential endogenous substrate for the hydroperoxidase. |
1986 |
J. Biol. Chem. |
pmid:3007487
|
Koizumi T et al. |
Identification of a cis-regulatory element for delta 12-prostaglandin J2-induced expression of the rat heme oxygenase gene. |
1995 |
J. Biol. Chem. |
pmid:7665598
|
Curfs DM et al. |
Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology. |
2008 |
J. Biol. Chem. |
pmid:18511424
|
Wang YL et al. |
Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival. |
2002 |
J. Biol. Chem. |
pmid:12082115
|
Hirata Y et al. |
Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine. |
1988 |
J. Biol. Chem. |
pmid:3053696
|
Wilhelm D et al. |
SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development. |
2007 |
J. Biol. Chem. |
pmid:17277314
|
Lennon AM et al. |
MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive oxygenated species. |
2002 |
J. Biol. Chem. |
pmid:12052825
|
Amir-Moazami O et al. |
Phospholipid scramblase 1 modulates a selected set of IgE receptor-mediated mast cell responses through LAT-dependent pathway. |
2008 |
J. Biol. Chem. |
pmid:18579528
|
Ma H et al. |
Estrogen-induced production of a peroxisome proliferator-activated receptor (PPAR) ligand in a PPARgamma-expressing tissue. |
1998 |
J. Biol. Chem. |
pmid:9804768
|
Hata AN et al. |
Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2. |
2005 |
J. Biol. Chem. |
pmid:16030019
|
Ryan AJ et al. |
15-deoxy-Delta12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferase. |
2008 |
J. Biol. Chem. |
pmid:18614529
|
Lapointe DS and Olson MS |
Platelet-activating factor-stimulated hepatic glycogenolysis is not mediated through cyclooxygenase-derived metabolites of arachidonic acid. |
1989 |
J. Biol. Chem. |
pmid:2501299
|
Urade Y et al. |
Mast cells contain spleen-type prostaglandin D synthetase. |
1990 |
J. Biol. Chem. |
pmid:2403560
|
Bishop-Bailey D and Hla T |
Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-Delta12, 14-prostaglandin J2. |
1999 |
J. Biol. Chem. |
pmid:10358055
|
Kwon G et al. |
Tumor necrosis factor alpha-induced pancreatic beta-cell insulin resistance is mediated by nitric oxide and prevented by 15-deoxy-Delta12,14-prostaglandin J2 and aminoguanidine. A role for peroxisome proliferator-activated receptor gamma activation and inos expression. |
1999 |
J. Biol. Chem. |
pmid:10373483
|
Stubbs VE et al. |
Indomethacin causes prostaglandin D(2)-like and eotaxin-like selective responses in eosinophils and basophils. |
2002 |
J. Biol. Chem. |
pmid:11980903
|
Watanabe K et al. |
Enzymatic formation of prostaglandin F2 alpha from prostaglandin H2 and D2. Purification and properties of prostaglandin F synthetase from bovine lung. |
1985 |
J. Biol. Chem. |
pmid:3858278
|
Lee TS et al. |
Induction of heme oxygenase-1 expression in murine macrophages is essential for the anti-inflammatory effect of low dose 15-deoxy-Delta 12,14-prostaglandin J2. |
2003 |
J. Biol. Chem. |
pmid:12642589
|
Richman JG et al. |
Nicotinic acid receptor agonists differentially activate downstream effectors. |
2007 |
J. Biol. Chem. |
pmid:17452318
|
Baek SJ et al. |
Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. |
2004 |
J. Biol. Chem. |
pmid:14662774
|
Schröder R et al. |
The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation. |
2009 |
J. Biol. Chem. |
pmid:19010788
|
Ho TC et al. |
15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53. |
2008 |
J. Biol. Chem. |
pmid:18718914
|
Zavoico GB et al. |
Regulation of intracellular pH in human platelets. Effects of thrombin, A23187, and ionomycin and evidence for activation of Na+/H+ exchange and its inhibition by amiloride analogs. |
1986 |
J. Biol. Chem. |
pmid:3020026
|
Liston TE and Roberts LJ |
Metabolic fate of radiolabeled prostaglandin D2 in a normal human male volunteer. |
1985 |
J. Biol. Chem. |
pmid:3863815
|
Hosoya T et al. |
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells. |
2005 |
J. Biol. Chem. |
pmid:15917255
|
Irikura D et al. |
Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase. |
2009 |
J. Biol. Chem. |
pmid:19131342
|
Armoni M et al. |
Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect. |
2003 |
J. Biol. Chem. |
pmid:12777391
|
Chen Y et al. |
Formation of reactive cyclopentenone compounds in vivo as products of the isoprostane pathway. |
1999 |
J. Biol. Chem. |
pmid:10196163
|
Caivano M et al. |
15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide. |
2003 |
J. Biol. Chem. |
pmid:14557273
|
Murakami M et al. |
Interleukin-3 regulates development of the 5-lipoxygenase/leukotriene C4 synthase pathway in mouse mast cells. |
1995 |
J. Biol. Chem. |
pmid:7559381
|
Xin X et al. |
Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. |
1999 |
J. Biol. Chem. |
pmid:10085162
|
Song WL et al. |
Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans. |
2008 |
J. Biol. Chem. |
pmid:17993463
|
Boie Y et al. |
Molecular cloning and characterization of the human prostanoid DP receptor. |
1995 |
J. Biol. Chem. |
pmid:7642548
|
Gao L et al. |
Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase. |
2003 |
J. Biol. Chem. |
pmid:12746435
|
Pérez-Sala D et al. |
Molecular basis for the direct inhibition of AP-1 DNA binding by 15-deoxy-Delta 12,14-prostaglandin J2. |
2003 |
J. Biol. Chem. |
pmid:14532268
|
Worley JR et al. |
Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid. |
2003 |
J. Biol. Chem. |
pmid:14534304
|
Lee S et al. |
Lipocalin-type prostaglandin D2 synthase protein regulates glial cell migration and morphology through myristoylated alanine-rich C-kinase substrate: prostaglandin D2-independent effects. |
2012 |
J. Biol. Chem. |
pmid:22275363
|
Nelson CA and Seamon KB |
Binding of [3H]forskolin to human platelet membranes. Regulation by guanyl-5'-yl imidodiphosphate, NaF, and prostaglandins E1 and D2. |
1986 |
J. Biol. Chem. |
pmid:3463564
|
Taketa K et al. |
Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages. |
2008 |
J. Biol. Chem. |
pmid:18208815
|
Lim SY et al. |
15-Deoxy-Delta12,14-prostaglandin J(2) protects against nitrosative PC12 cell death through up-regulation of intracellular glutathione synthesis. |
2004 |
J. Biol. Chem. |
pmid:15319433
|
Shibata T et al. |
Thioredoxin as a molecular target of cyclopentenone prostaglandins. |
2003 |
J. Biol. Chem. |
pmid:12709421
|
Murakami M et al. |
Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells. |
1994 |
J. Biol. Chem. |
pmid:8071353
|
Yu X et al. |
Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-Delta12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase. |
2006 |
J. Biol. Chem. |
pmid:16857669
|
Chen ZH et al. |
Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. |
2006 |
J. Biol. Chem. |
pmid:16565077
|
Feinstein MB et al. |
Reversal of thrombin-induced myosin phosphorylation and the assembly of cytoskeletal structures in platelets by the adenylate cyclase stimulants prostaglandin D2 and forskolin. |
1983 |
J. Biol. Chem. |
pmid:6571835
|
Shan ZZ et al. |
A potential role of 15-deoxy-delta(12,14)-prostaglandin J2 for induction of human articular chondrocyte apoptosis in arthritis. |
2004 |
J. Biol. Chem. |
pmid:15213234
|
Park EJ et al. |
15d-PGJ2 and rosiglitazone suppress Janus kinase-STAT inflammatory signaling through induction of suppressor of cytokine signaling 1 (SOCS1) and SOCS3 in glia. |
2003 |
J. Biol. Chem. |
pmid:12584205
|
Ruiz PA et al. |
15-deoxy-delta12,14-prostaglandin J2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through modulation of protein phosphatase 2A activity. |
2004 |
J. Biol. Chem. |
pmid:15199053
|
Fitzpatrick FA and Wynalda MA |
Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro. |
1983 |
J. Biol. Chem. |
pmid:6578214
|
Pugliese G et al. |
Hepatic transformation of prostaglandin D2 to a new prostanoid, 9 alpha,11 beta-prostaglandin F2, that inhibits platelet aggregation and constricts blood vessels. |
1985 |
J. Biol. Chem. |
pmid:3863819
|
Li L et al. |
RasGRP4 regulates the expression of prostaglandin D2 in human and rat mast cell lines. |
2003 |
J. Biol. Chem. |
pmid:12493770
|
Clay CE et al. |
Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells. |
2001 |
J. Biol. Chem. |
pmid:11668172
|
Manna JD et al. |
Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells. |
2014 |
J. Biol. Chem. |
pmid:25301951
|
Hilliard M et al. |
The anti-inflammatory prostaglandin 15-deoxy-delta(12,14)-PGJ2 inhibits CRM1-dependent nuclear protein export. |
2010 |
J. Biol. Chem. |
pmid:20457605
|
Paruchuri S et al. |
Leukotriene E4 activates peroxisome proliferator-activated receptor gamma and induces prostaglandin D2 generation by human mast cells. |
2008 |
J. Biol. Chem. |
pmid:18411276
|
Undem BJ et al. |
Inhibition by adenosine 3':5'-monophosphate of eicosanoid and platelet-activating factor biosynthesis in the mouse PT-18 mast cell. |
1990 |
J. Biol. Chem. |
pmid:1691175
|
Cernuda-Morollón E et al. |
15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit. |
2001 |
J. Biol. Chem. |
pmid:11466314
|
Shiraya K et al. |
A novel transporter of SLC22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules. |
2010 |
J. Biol. Chem. |
pmid:20448048
|
Guo N et al. |
Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease. |
2010 |
J. Biol. Chem. |
pmid:20308056
|
Hunter JG et al. |
Peroxisome proliferator-activated receptor gamma ligands differentially modulate muscle cell differentiation and MyoD gene expression via peroxisome proliferator-activated receptor gamma -dependent and -independent pathways. |
2001 |
J. Biol. Chem. |
pmid:11477074
|