PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

Cross Reference

Introduction

To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PGD2?

PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PGD2

MeSH term MeSH ID Detail
Choroid Diseases D015862 2 associated lipids
Nasal Obstruction D015508 4 associated lipids
HTLV-I Infections D015490 3 associated lipids
Leukemia, Basophilic, Acute D015471 9 associated lipids
Leukemia, T-Cell D015458 23 associated lipids
Leukemia, B-Cell D015448 3 associated lipids
Weight Loss D015431 56 associated lipids
Reperfusion Injury D015427 65 associated lipids
Zollinger-Ellison Syndrome D015043 1 associated lipids
Xeroderma Pigmentosum D014983 6 associated lipids
Wounds, Stab D014951 3 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Urticaria Pigmentosa D014582 4 associated lipids
Urticaria D014581 13 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Uremia D014511 33 associated lipids
Trigeminal Neuralgia D014277 1 associated lipids
Translocation, Genetic D014178 20 associated lipids
Thyroiditis, Autoimmune D013967 9 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Per page 10 20 50 100 | Total 189

PubChem Associated disorders and diseases

What pathways are associated with PGD2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PGD2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PGD2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PGD2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PGD2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PGD2?

Knock-out

Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).

Rodent Model

Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PGD2

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Per page 10 20 50 100 | Total 3138
Authors Title Published Journal PubMed Link
Kase K et al. Inhibitory action of roxithromycin on histamine release and prostaglandin D2 production from beta-defensin 2-stimulated mast cells. 2009 Int. J. Mol. Med. pmid:19212651
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Quarello E and Trabbia A High-definition flow combined with spatiotemporal image correlation in the diagnosis of fetal coarctation of the aorta. 2009 Ultrasound Obstet Gynecol pmid:19194864
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Kolaczkowska E et al. Increased cyclooxygenase activity impairs apoptosis of inflammatory neutrophils in mice lacking gelatinase B/matrix metalloproteinase-9. 2009 Immunology pmid:19175797
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Cocca C et al. 15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest. 2009 Biochem. Pharmacol. pmid:19576185
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Comabella M et al. Plasma levels of 15d-PGJ are not altered in multiple sclerosis. 2009 Eur. J. Neurol. pmid:19538219
Qin HD et al. Upregulation of peroxisome proliferator-activated receptor-gamma and NADPH oxidases are involved in restenosis after balloon injury. 2009 J. Cell. Physiol. pmid:19562688
Leduc M et al. Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands. 2009 J. Pharmacol. Exp. Ther. pmid:19584306
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