Kim S et al. |
Synthesis of 15R-PGD2: a potential DP2 receptor agonist. |
2005 |
Bioorg. Med. Chem. Lett. |
pmid:15780624
|
Marshall JC |
Modeling MODS: what can be learned from animal models of the multiple-organ dysfunction syndrome? |
2005 |
Intensive Care Med |
pmid:15782317
|
Gazi L et al. |
Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes. |
2005 |
Prostaglandins Other Lipid Mediat. |
pmid:15789622
|
Fowler CJ and Tiger G |
Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro. |
2005 |
Biochem. Pharmacol. |
pmid:15794945
|
Dore-Duffy P et al. |
The CNS pericyte response to low oxygen: early synthesis of cyclopentenone prostaglandins of the J-series. |
2005 |
Microvasc. Res. |
pmid:15797264
|
Liu J et al. |
Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells. |
2005 |
Cancer Chemother. Pharmacol. |
pmid:15838654
|
Ji JD et al. |
Inhibition of IL-10-induced STAT3 activation by 15-deoxy-Delta12,14-prostaglandin J2. |
2005 |
Rheumatology (Oxford) |
pmid:15840591
|
Mitchell MD et al. |
Identification of 9alpha,11beta-prostaglandin F2 in human amniotic fluid and characterization of its production by human gestational tissues. |
2005 |
J. Clin. Endocrinol. Metab. |
pmid:15840748
|
Usui S et al. |
Design, synthesis, and biological activity of novel PPARgamma ligands based on rosiglitazone and 15d-PGJ2. |
2005 |
Bioorg. Med. Chem. Lett. |
pmid:15745794
|
Storer PD et al. |
Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis. |
2005 |
J. Neuroimmunol. |
pmid:15748950
|
Spik I et al. |
Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouse. |
2005 |
J. Immunol. |
pmid:15749909
|
Mochizuki M et al. |
Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury. |
2005 |
Am. J. Respir. Crit. Care Med. |
pmid:15750045
|
Moulin D et al. |
Rosiglitazone induces interleukin-1 receptor antagonist in interleukin-1beta-stimulated rat synovial fibroblasts via a peroxisome proliferator-activated receptor beta/delta-dependent mechanism. |
2005 |
Arthritis Rheum. |
pmid:15751073
|
Viñals M et al. |
Aspirin increases CD36, SR-BI, and ABCA1 expression in human THP-1 macrophages. |
2005 |
Cardiovasc. Res. |
pmid:15769457
|
Yuan Z et al. |
Cardioprotective effects of peroxisome proliferator activated receptor gamma activators on acute myocarditis: anti-inflammatory actions associated with nuclear factor kappaB blockade. |
2005 |
Heart |
pmid:15774612
|
Wu CC et al. |
2-(2-Br-phenyl)-8-methoxy-benzoxazinone (HPW-RX2), a direct thrombin inhibitor with a suppressive effect on thromboxane formation in platelets. |
2005 |
Eur. J. Pharmacol. |
pmid:16313903
|
Son JK et al. |
Ginkgetin, a Biflavone from Ginko biloba leaves, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. |
2005 |
Biol. Pharm. Bull. |
pmid:16327145
|
Nakajima N et al. |
[Alternation of ion transport of airway epithelium by eicosanoids]. |
2005 |
Arerugi |
pmid:16407682
|
Benyó Z et al. |
GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing. |
2005 |
J. Clin. Invest. |
pmid:16322797
|
Coyle AT et al. |
15-deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells. |
2005 |
FEBS J. |
pmid:16156795
|
Chen WC et al. |
Induction of apoptosis in colorectal cancer cells by peroxisome proliferators-activated receptor gamma activation up-regulating PTEN and inhibiting PI3K activity. |
2005 |
Chin. Med. J. |
pmid:16157051
|
Uehara Y |
[Prostaglandin D2]. |
2005 |
Nippon Rinsho |
pmid:16149440
|
Zamuner SR et al. |
Predisposition to colorectal cancer in rats with resolved colitis: role of cyclooxygenase-2-derived prostaglandin d2. |
2005 |
Am. J. Pathol. |
pmid:16251413
|
Negoro H et al. |
Endogenous prostaglandin D(2) synthesis decreases vascular cell adhesion molecule-1 expression in human umbilical vein endothelial cells. |
2005 |
Life Sci. |
pmid:16154157
|
O'Flaherty JT et al. |
5-Oxo-ETE analogs and the proliferation of cancer cells. |
2005 |
Biochim. Biophys. Acta |
pmid:16154383
|
Schmidt R et al. |
LC-MS/MS-analysis of prostaglandin E2 and D2 in microdialysis samples of rats. |
2005 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:16172029
|
Wilhelm D et al. |
Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. |
2005 |
Dev. Biol. |
pmid:16185683
|
Jawerbaum A et al. |
Peroxynitrites and impaired modulation of nitric oxide concentrations in embryos from diabetic rats during early organogenesis. |
2005 |
Reproduction |
pmid:16264098
|
Armer RE et al. |
Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2. |
2005 |
J. Med. Chem. |
pmid:16190744
|
Bianchi A et al. |
Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2. |
2005 |
Arthritis Res. Ther. |
pmid:16277686
|
Shibata T and Uchida K |
[Current opinions on prostaglandin J2]. |
2005 |
Seikagaku |
pmid:16241007
|
Shiraishi Y et al. |
Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15528449
|
Chen HH et al. |
Effects of trichloroethylene and perchloroethylene on muscle contractile responses and epithelial prostaglandin release and acetylcholinesterase activity in swine trachea. |
2005 |
Toxicol. Sci. |
pmid:15496499
|
Piva R et al. |
15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins. |
2005 |
Blood |
pmid:15498850
|
Appel S et al. |
PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways. |
2005 |
Blood |
pmid:16105976
|
Boyce JA |
Eicosanoid mediators of mast cells: receptors, regulation of synthesis, and pathobiologic implications. |
2005 |
Chem Immunol Allergy |
pmid:16107763
|
Hata AN et al. |
Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2. |
2005 |
J. Biol. Chem. |
pmid:16030019
|
Motilva V et al. |
COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions. |
2005 |
Int. Immunopharmacol. |
pmid:15652766
|
MartÃnez B et al. |
The mitochondrial respiratory complex I is a target for 15-deoxy-delta12,14-prostaglandin J2 action. |
2005 |
J. Lipid Res. |
pmid:15654126
|
Liang X et al. |
Prostaglandin D2 mediates neuronal protection via the DP1 receptor. |
2005 |
J. Neurochem. |
pmid:15659218
|
Shen ZN et al. |
Suppression of chondrosarcoma cells by 15-deoxy-Delta 12,14-prostaglandin J2 is associated with altered expression of Bax/Bcl-xL and p21. |
2005 |
Biochem. Biophys. Res. Commun. |
pmid:15694358
|
Shiraki T et al. |
Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma. |
2005 |
J. Biol. Chem. |
pmid:15695504
|
Bulló M et al. |
Stimulation of NGF expression and secretion in 3T3-L1 adipocytes by prostaglandins PGD2, PGJ2, and Delta12-PGJ2. |
2005 |
Am. J. Physiol. Endocrinol. Metab. |
pmid:15713689
|
GarcÃa-Bueno B et al. |
The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in rats. |
2005 |
Psychopharmacology (Berl.) |
pmid:15719215
|
Storer PD et al. |
Cyclopentenone prostaglandins PGA2 and 15-deoxy-delta12,14 PGJ2 suppress activation of murine microglia and astrocytes: implications for multiple sclerosis. |
2005 |
J. Neurosci. Res. |
pmid:15723383
|
Migita H and Morser J |
15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) signals through retinoic acid receptor-related orphan receptor-alpha but not peroxisome proliferator-activated receptor-gamma in human vascular endothelial cells: the effect of 15d-PGJ2 on tumor necrosis factor-alpha-induced gene expression. |
2005 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15662020
|
Andrews WJ et al. |
Aromatase inhibition by 15-deoxy-prostaglandin J(2) (15-dPGJ(2)) and N-(4-hydroxyphenyl)-retinamide (4HPR) is associated with enhanced ceramide production. |
2005 |
J. Steroid Biochem. Mol. Biol. |
pmid:15862961
|
Allred CD and Kilgore MW |
Selective activation of PPARgamma in breast, colon, and lung cancer cell lines. |
2005 |
Mol. Cell. Endocrinol. |
pmid:15866424
|
Marzocco S et al. |
The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock. |
2005 |
Intensive Care Med |
pmid:15868139
|
Yoshida M et al. |
Methotrexate suppresses inflammatory agonist induced interleukin 6 synthesis in osteoblasts. |
2005 |
J. Rheumatol. |
pmid:15868610
|
Li X et al. |
Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes. |
2005 |
J. Rheumatol. |
pmid:15868626
|
De Oliveira C et al. |
Insulin alters nuclear factor-lambdaB and peroxisome proliferator-activated receptor-gamma protein expression induced by glycated bovine serum albumin in vascular smooth-muscle cells. |
2005 |
J. Lab. Clin. Med. |
pmid:15871306
|
Planagumà A et al. |
The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation. |
2005 |
FASEB J. |
pmid:15876570
|
Kim HY et al. |
Upregulation of LPS-induced chemokine KC expression by 15-deoxy-delta12,14-prostaglandin J2 in mouse peritoneal macrophages. |
2005 |
Immunol. Cell Biol. |
pmid:15877607
|
Blanco M et al. |
Increased plasma levels of 15-deoxyDelta prostaglandin J2 are associated with good outcome in acute atherothrombotic ischemic stroke. |
2005 |
Stroke |
pmid:15879329
|
Hashimoto Y et al. |
Prostaglandin D2 inhibits IgE-mediated scratching by suppressing histamine release from mast cells. |
2005 |
J. Pharmacol. Sci. |
pmid:15879676
|
MartÃn AR et al. |
The COX-2 inhibitor, rofecoxib, ameliorates dextran sulphate sodium induced colitis in mice. |
2005 |
Inflamm. Res. |
pmid:15883736
|
Chen YC et al. |
Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species. |
2005 |
Biochim. Biophys. Acta |
pmid:15843042
|
Ackerman WE et al. |
Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkappaB signal disruption in human WISH and amnion cells. |
2005 |
Biol. Reprod. |
pmid:15843495
|
Drew PD et al. |
Hormone regulation of microglial cell activation: relevance to multiple sclerosis. |
2005 |
Brain Res. Brain Res. Rev. |
pmid:15850670
|
Gallant MA et al. |
Production of prostaglandin D(2) by human osteoblasts and modulation of osteoprotegerin, RANKL, and cellular migration by DP and CRTH2 receptors. |
2005 |
J. Bone Miner. Res. |
pmid:15765187
|
Kämpfer H et al. |
Wound inflammation in diabetic ob/ob mice: functional coupling of prostaglandin biosynthesis to cyclooxygenase-1 activity in diabetes-impaired wound healing. |
2005 |
Diabetes |
pmid:15855344
|
Saito H |
[Mast cells]. |
2005 |
Nippon Rinsho |
pmid:15861652
|
Kaplan JM et al. |
15-Deoxy-delta(12,14)-prostaglandin J(2) (15D-PGJ(2)), a peroxisome proliferator activated receptor gamma ligand, reduces tissue leukosequestration and mortality in endotoxic shock. |
2005 |
Shock |
pmid:15988322
|
Tomita H et al. |
Troglitazone and 15-deoxy-delta(12,14)-prostaglandin J2 inhibit shear-induced coupling factor 6 release in endothelial cells. |
2005 |
Cardiovasc. Res. |
pmid:15949477
|
Marchini C et al. |
Aspirin modulates LPS-induced nitric oxide release in rat glial cells. |
2005 Jun 10-17 |
Neurosci. Lett. |
pmid:15882795
|
Calabrò P et al. |
Inhibition of tumor-necrosis-factor-alpha induced endothelial cell activation by a new class of PPAR-gamma agonists. An in vitro study showing receptor-independent effects. |
2005 Nov-Dec |
J. Vasc. Res. |
pmid:16155367
|
Kang DS et al. |
15-deoxy-Delta12,14-prostaglandin J2 induces renal epithelial cell death through NF-kappaB-dependent and MAPK-independent mechanism. |
2006 |
Toxicol. Appl. Pharmacol. |
pmid:16890972
|
Nakata S et al. |
15-Deoxy-Delta12,14-prostaglandin J(2) induces death receptor 5 expression through mRNA stabilization independently of PPARgamma and potentiates TRAIL-induced apoptosis. |
2006 |
Mol. Cancer Ther. |
pmid:16891469
|
Wang XS and Lau HY |
Beta-adrenoceptor-mediated inhibition of mediator release from human peripheral blood-derived mast cells. |
2006 |
Clin. Exp. Pharmacol. Physiol. |
pmid:16895550
|
Zhang A et al. |
Prostaglandin D2 inhibits TGF-beta1-induced epithelial-to-mesenchymal transition in MDCK cells. |
2006 |
Am. J. Physiol. Renal Physiol. |
pmid:16896186
|
Chaffer CL et al. |
PPARgamma-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma. |
2006 |
BMC Cancer |
pmid:16519808
|
Pérez S et al. |
The 2-series prostaglandins suppress VLDL secretion in an inflammatory condition-dependent manner in primary rat hepatocytes. |
2006 |
Biochim. Biophys. Acta |
pmid:16545597
|
Wise H |
Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells. |
2006 |
Eur. J. Pharmacol. |
pmid:16545798
|
Wang XS et al. |
Functional characterization of human mast cells cultured from adult peripheral blood. |
2006 |
Int. Immunopharmacol. |
pmid:16546715
|
Shimizu T et al. |
A role of PPAR-gamma in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage. |
2006 |
Ann. Surg. |
pmid:16794398
|
Chen Y et al. |
Effects of PPARgamma agonists on cell survival and focal adhesions in a Chinese thyroid carcinoma cell line. |
2006 |
J. Cell. Biochem. |
pmid:16795079
|
Yucel-Lindberg T et al. |
Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts. |
2006 |
Cell. Signal. |
pmid:16766159
|
Relic B et al. |
Peroxisome proliferator-activated receptor-gamma1 is dephosphorylated and degraded during BAY 11-7085-induced synovial fibroblast apoptosis. |
2006 |
J. Biol. Chem. |
pmid:16766531
|
Sugimoto M et al. |
Role of COX-1 and COX-2 on skin PGs biosynthesis by mechanical scratching in mice. |
2006 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:16815697
|
Schwartz MS et al. |
Determination of a prostaglandin D2 antagonist and its acyl glucuronide metabolite in human plasma by high performance liquid chromatography with tandem mass spectrometric detection--a lack of MS/MS selectivity between a glucuronide conjugate and a phase I metabolite. |
2006 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:16716772
|
Na HK and Surh YJ |
Transcriptional regulation via cysteine thiol modification: a novel molecular strategy for chemoprevention and cytoprotection. |
2006 |
Mol. Carcinog. |
pmid:16673384
|
BrazÃs P et al. |
Dermal microdialysis in the dog: in vivo assessment of the effect of cyclosporin A on cutaneous histamine and prostaglandin D2 release. |
2006 |
Vet. Dermatol. |
pmid:16674731
|
Ye P et al. |
[The role of peroxisome proliferator-activated receptor gamma in proliferation of cardiac non myocytes]. |
2006 |
Zhongguo Ying Yong Sheng Li Xue Za Zhi |
pmid:21162229
|
Garg TK and Chang JY |
Methylmercury causes oxidative stress and cytotoxicity in microglia: attenuation by 15-deoxy-delta 12, 14-prostaglandin J2. |
2006 |
J. Neuroimmunol. |
pmid:16225932
|
Shiraki T et al. |
Spectroscopic analyses of the binding kinetics of 15d-PGJ2 to the PPARgamma ligand-binding domain by multi-wavelength global fitting. |
2006 |
Biochem. J. |
pmid:16236024
|
Millán O et al. |
Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis. |
2006 |
Carcinogenesis |
pmid:16113051
|
Willermain F et al. |
15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16939878
|
Lim HJ et al. |
PPARgamma activation induces CD36 expression and stimulates foam cell like changes in rVSMCs. |
2006 |
Prostaglandins Other Lipid Mediat. |
pmid:16939881
|
Chiba T et al. |
Prostaglandin D2 induces IL-8 and GM-CSF by bronchial epithelial cells in a CRTH2-independent pathway. |
2006 |
Int. Arch. Allergy Immunol. |
pmid:16940740
|
Yu X et al. |
Nrf2-mediated induction of cytoprotective enzymes by 15-deoxy-Delta12,14-prostaglandin J2 is attenuated by alkenal/one oxidoreductase. |
2006 |
J. Biol. Chem. |
pmid:16857669
|
Chen ZH et al. |
Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms. |
2006 |
J. Biol. Chem. |
pmid:16565077
|
Horiguchi T et al. |
Cyclooxygenase-2 mediates the development of cortical spreading depression-induced tolerance to transient focal cerebral ischemia in rats. |
2006 |
Neuroscience |
pmid:16567054
|
Siddhivarn C et al. |
Prostaglandin D2 pathway and peroxisome proliferator-activated receptor gamma-1 expression are induced by mechanical loading in an osteoblastic cell line. |
2006 |
J. Periodont. Res. |
pmid:16499711
|
Coyle AT and Kinsella BT |
Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells. |
2006 |
Biochem. Pharmacol. |
pmid:16499875
|
Ye F et al. |
Quantitative characterization of 15-deoxy-delta(12,14)-prostaglandin J2 in regulating EGFPSmad2 translocation in CHO cells through PPARgamma/TGFbeta/Smad2 pathway. |
2006 |
Cell. Physiol. Biochem. |
pmid:16914899
|
Lee JJ et al. |
Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization. |
2006 |
Vascul. Pharmacol. |
pmid:16916624
|
Ulven T and Kostenis E |
Targeting the prostaglandin D2 receptors DP and CRTH2 for treatment of inflammation. |
2006 |
Curr Top Med Chem |
pmid:16918458
|
Theiner G et al. |
The mast cell mediator PGD2 suppresses IL-12 release by dendritic cells leading to Th2 polarized immune responses in vivo. |
2006 |
Immunobiology |
pmid:16920486
|
Urade Y and Mohri I |
[Sleep and brain function]. |
2006 |
No To Hattatsu |
pmid:16986732
|