Yang G et al. |
Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism. |
2012 |
PLoS ONE |
pmid:22899986
|
Wang P et al. |
The antagonistic actions of endogenous interleukin-1β and 15-deoxy-Δ12,14-prostaglandin J2 regulate the temporal synthesis of matrix metalloproteinase-9 in sheared chondrocytes. |
2012 |
J. Biol. Chem. |
pmid:22829602
|
Nicholson JD et al. |
PGJ(2) provides prolonged CNS stroke protection by reducing white matter edema. |
2012 |
PLoS ONE |
pmid:23284631
|
Xiao L et al. |
Lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 mediates late-phase PGE2 production in bone marrow derived macrophages. |
2012 |
PLoS ONE |
pmid:23226252
|
Sykes L et al. |
Chemoattractant receptor homologous to the T helper 2 cell (CRTH2) is not expressed in human amniocytes and myocytes. |
2012 |
PLoS ONE |
pmid:23226366
|
Yamaura K et al. |
Repeated application of glucocorticoids exacerbate pruritus via inhibition of prostaglandin D2 production of mast cells in a murine model of allergic contact dermatitis. |
2012 |
J Toxicol Sci |
pmid:23208428
|
Wang Y et al. |
Optimization of phenylacetic acid derivatives for CRTH2 and DP selective antagonism. |
2012 |
Bioorg. Med. Chem. Lett. |
pmid:22119474
|
Hossain MS et al. |
Stable expression of lipocalin-type prostaglandin D synthase in cultured preadipocytes impairs adipogenesis program independently of endogenous prostanoids. |
2012 |
Exp. Cell Res. |
pmid:22100987
|
Paulitschke V et al. |
Proteome analysis identified the PPARγ ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction. |
2012 |
PLoS ONE |
pmid:23049949
|
Syeda PK et al. |
A monoclonal antibody specific for Δ12-prostaglandin J2 and its utilization in the immunological assay in cell culture system of adipocytes. |
2012 |
Hybridoma (Larchmt) |
pmid:23098304
|
Weng Y et al. |
Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception. |
2012 |
Mol Pain |
pmid:23013719
|
Bardelli C et al. |
Autocrine activation of human monocyte/macrophages by monocyte-derived microparticles and modulation by PPARγ ligands. |
2012 |
Br. J. Pharmacol. |
pmid:21745193
|
Chae HS and Chin YW |
Anti-allergic effect of lambertianic acid from Thuja orientalis in mouse bone marrow-derived mast cells. |
2012 |
Immunopharmacol Immunotoxicol |
pmid:21854102
|
Miyawaki T et al. |
Combination of midazolam and a cyclooxygenase-2 inhibitor inhibits lipopolysaccharide-induced interleukin-6 production in human peripheral blood mononuclear cells. |
2012 |
Immunopharmacol Immunotoxicol |
pmid:21854184
|
Maicas N et al. |
Prostaglandin D2 regulates joint inflammation and destruction in murine collagen-induced arthritis. |
2012 |
Arthritis Rheum. |
pmid:21898357
|
Kanakasabai S et al. |
PPARγ agonists promote oligodendrocyte differentiation of neural stem cells by modulating stemness and differentiation genes. |
2012 |
PLoS ONE |
pmid:23185633
|
Sedej M et al. |
D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells. |
2012 |
J. Allergy Clin. Immunol. |
pmid:21930295
|
Xue L et al. |
Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2. |
2012 |
J. Immunol. |
pmid:22174450
|
He S et al. |
Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella). |
2012 |
Comp. Biochem. Physiol. C Toxicol. Pharmacol. |
pmid:22079418
|
Hogrefe C et al. |
Single impact cartilage trauma and TNF-α: interactive effects do not increase early cell death and indicate the need for bi-/multidirectional therapeutic approaches. |
2012 |
Int. J. Mol. Med. |
pmid:22922824
|
Lee E et al. |
15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes. |
2012 |
Free Radic. Biol. Med. |
pmid:22245093
|
Lee S et al. |
Lipocalin-type prostaglandin D2 synthase protein regulates glial cell migration and morphology through myristoylated alanine-rich C-kinase substrate: prostaglandin D2-independent effects. |
2012 |
J. Biol. Chem. |
pmid:22275363
|
Ledwidge MT et al. |
In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin? |
2012 |
Atherosclerosis |
pmid:22326030
|
Baek K et al. |
Myeloid Elf-1-like factor stimulates adipogenic differentiation through the induction of peroxisome proliferator-activated receptor γ expression in bone marrow. |
2012 |
J. Cell. Physiol. |
pmid:22307523
|
MartÃnez AE et al. |
15-Deoxy-Δ(12,14)-prostaglandin J2 exerts pro- and anti-inflammatory effects in mesangial cells in a concentration-dependent manner. |
2012 |
Inflamm Allergy Drug Targets |
pmid:22309084
|
Fujita M et al. |
Cytotoxicity of 15-deoxy-Δ(12,14)-prostaglandin J(2) through PPARγ-independent pathway and the involvement of the JNK and Akt pathway in renal cell carcinoma. |
2012 |
Int J Med Sci |
pmid:22991494
|
Ito H et al. |
PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis. |
2012 |
J. Am. Soc. Nephrol. |
pmid:22997255
|
Wu CC et al. |
Involvement of the prostaglandin D2 signal pathway in retinoid-inducible gene 1 (RIG1)-mediated suppression of cell invasion in testis cancer cells. |
2012 |
Biochim. Biophys. Acta |
pmid:22960220
|
Song HH et al. |
Anti-inflammatory and anti-allergic effect of Agaricus blazei extract in bone marrow-derived mast cells. |
2012 |
Am. J. Chin. Med. |
pmid:22928836
|
Tachikawa M et al. |
A clearance system for prostaglandin D2, a sleep-promoting factor, in cerebrospinal fluid: role of the blood-cerebrospinal barrier transporters. |
2012 |
J. Pharmacol. Exp. Ther. |
pmid:22931759
|
Fredman G et al. |
Self-limited versus delayed resolution of acute inflammation: temporal regulation of pro-resolving mediators and microRNA. |
2012 |
Sci Rep |
pmid:22957142
|
Yang K et al. |
[Changes of prostaglandin D2,carboxypeptidase A3 and platelet activating factor in guinea pig in anaphylactic shock]. |
2012 |
Fa Yi Xue Za Zhi |
pmid:22812216
|
Komoda T and Nishikawa M |
6'-Hydroxyoxosorbicillinol, a new lipoxygenase inhibitor and PGD2/LTB4 release suppressor from Penicillium sp. |
2012 |
Biosci. Biotechnol. Biochem. |
pmid:22785490
|
Joo M and Sadikot RT |
PGD synthase and PGD2 in immune resposne. |
2012 |
Mediators Inflamm. |
pmid:22791937
|
Baudouin-Legros M et al. |
Long-term CFTR inhibition modulates 15d-prostaglandin J2 in human pulmonary cells. |
2012 |
Int. J. Biochem. Cell Biol. |
pmid:22481026
|
Weng Z et al. |
Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans. |
2012 |
PLoS ONE |
pmid:22470478
|
Takahashi G et al. |
The potential role of prostaglandin D2 in nasal congestion observed in a guinea pig model of allergic rhinitis. |
2012 |
Int. Arch. Allergy Immunol. |
pmid:22472859
|
Abdo H et al. |
The omega-6 fatty acid derivative 15-deoxy-Δ¹²,¹â´-prostaglandin J2 is involved in neuroprotection by enteric glial cells against oxidative stress. |
2012 |
J. Physiol. (Lond.) |
pmid:22473776
|
Ji Y et al. |
Activation of rat intestinal mucosal mast cells by fat absorption. |
2012 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:22461027
|
Kim SE et al. |
15-deoxy-Δ¹²,¹ⴠ-prostaglandin J₂ inhibits human immunodeficiency virus-1 tat-induced monocyte chemoattractant protein-1/CCL2 production by blocking the extracellular signal-regulated kinase-1/2 signaling pathway independently of peroxisome proliferator-activated receptor-γ and heme oxygenase-1 in rat hippocampal slices. |
2012 |
J. Neurosci. Res. |
pmid:22487967
|
Garza LA et al. |
Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. |
2012 |
Sci Transl Med |
pmid:22440736
|
Cloutier A et al. |
The prostanoid 15-deoxy-Δ12,14-prostaglandin-j2 reduces lung inflammation and protects mice against lethal influenza infection. |
2012 |
J. Infect. Dis. |
pmid:22219346
|
Sykes L et al. |
Changes in the Th1:Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-Δ(12,14)-prostaglandin J2. |
2012 |
Mediators Inflamm. |
pmid:22690041
|
Quinteiro MS et al. |
The indirect antinociceptive mechanism of 15d-PGJ2 on rheumatoid arthritis-induced TMJ inflammatory pain in rats. |
2012 |
Eur J Pain |
pmid:22354681
|
Prage EB et al. |
Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2). |
2012 |
Biochemistry |
pmid:22356188
|
Numazawa S et al. |
Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells. |
2012 |
Biol. Pharm. Bull. |
pmid:22382320
|
Lin YC et al. |
The glutathionylation of p65 modulates NF-κB activity in 15-deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚-treated endothelial cells. |
2012 |
Free Radic. Biol. Med. |
pmid:22387200
|
Carsin A et al. |
[Physiopathology of aspirin intolerant asthma]. |
2012 |
Rev Mal Respir |
pmid:22405107
|
Song WL et al. |
Niacin and biosynthesis of PGDâ‚‚by platelet COX-1 in mice and humans. |
2012 |
J. Clin. Invest. |
pmid:22406532
|
Nagata N and Urade Y |
[Endogenous sleep-promoting substance]. |
2012 |
Nippon Rinsho |
pmid:22844810
|
Philipose S et al. |
Laropiprant attenuates EP3 and TP prostanoid receptor-mediated thrombus formation. |
2012 |
PLoS ONE |
pmid:22870195
|
Mor A et al. |
Inhibitory effect of farnesylthiosalicylic acid on mediators release by mast cells: preferential inhibition of prostaglandin D(2) and tumor necrosis factor-α release. |
2011 |
Inflammation |
pmid:20706780
|
Balzar S et al. |
Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program. |
2011 |
Am. J. Respir. Crit. Care Med. |
pmid:20813890
|
Mathurin K et al. |
An interaction between L-prostaglandin D synthase and arrestin increases PGD2 production. |
2011 |
J. Biol. Chem. |
pmid:21112970
|
Wingard CJ et al. |
Mast cells contribute to altered vascular reactivity and ischemia-reperfusion injury following cerium oxide nanoparticle instillation. |
2011 |
Nanotoxicology |
pmid:21043986
|
Joachim A and Ruttkowski B |
Prostaglandin D(2) synthesis in Oesophagostomum dentatum is mediated by cytosolic glutathione S-transferase. |
2011 |
Exp. Parasitol. |
pmid:21056037
|
Lotz C et al. |
Peroxisome-proliferator-activated receptor γ mediates the second window of anaesthetic-induced preconditioning. |
2011 |
Exp. Physiol. |
pmid:21123361
|
Tsujita T et al. |
Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish. |
2011 |
Genes Cells |
pmid:21143560
|
Cha B et al. |
15-deoxy-D12,14-prostaglandin J2 suppresses RANTES expression by inhibiting NADPH oxidase activation in Helicobacter pylori-infected gastric epithelial cells. |
2011 |
J. Physiol. Pharmacol. |
pmid:21673364
|
Maekawa N et al. |
High-performance affinity purification for identification of 15-deoxy-Δ 12,14 -PGJ₂ interacting factors using magnetic nanobeads. |
2011 |
Biomed. Chromatogr. |
pmid:21374648
|
Kane CJ et al. |
Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. |
2011 |
Brain Behav. Immun. |
pmid:21376806
|
Arima M and Fukuda T |
Prostaglandin Dâ‚‚ and T(H)2 inflammation in the pathogenesis of bronchial asthma. |
2011 |
Korean J. Intern. Med. |
pmid:21437156
|
Luna-Gomes T et al. |
Eosinophils as a novel cell source of prostaglandin D2: autocrine role in allergic inflammation. |
2011 |
J. Immunol. |
pmid:22102725
|
MartÃnez-Gras I et al. |
The anti-inflammatory prostaglandin 15d-PGJ2 and its nuclear receptor PPARgamma are decreased in schizophrenia. |
2011 |
Schizophr. Res. |
pmid:21334179
|
Zhao J et al. |
Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice. |
2011 |
J. Clin. Invest. |
pmid:22105170
|
Chbicheb S et al. |
EGR1 expression: a calcium and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12,14-prostaglandin J2 and thiazolidinediones in breast cancer cells. |
2011 |
Biochem. Pharmacol. |
pmid:21338579
|
Braciale TJ and Kim TS |
Slowing down with age: lung DCs do it too. |
2011 |
J. Clin. Invest. |
pmid:22105176
|
Qiu Z et al. |
Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux. |
2011 |
Respirology |
pmid:21342332
|
Wang JJ and Mak OT |
Induction of apoptosis by 15d-PGJ2 via ROS formation: an alternative pathway without PPARγ activation in non-small cell lung carcinoma A549 cells. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21396480
|
Murata T et al. |
Prostagladin D2 is a mast cell-derived antiangiogenic factor in lung carcinoma. |
2011 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:22106279
|
Yamamoto Y et al. |
Proteomic identification of protein targets for 15-deoxy-Δ(12,14)-prostaglandin J2 in neuronal plasma membrane. |
2011 |
PLoS ONE |
pmid:21445266
|
Mackay GA and Stewart AG |
R2D(2) for C(4)Eo: an 'alliance' of PGD(2) receptors is required for LTC(4) production by human eosinophils. |
2011 |
Br. J. Pharmacol. |
pmid:21426314
|
Huang ZL et al. |
The role of adenosine in the regulation of sleep. |
2011 |
Curr Top Med Chem |
pmid:21401496
|
Osanai T and Okumura K |
Lipocalin-type PGD synthase as a novel biomarker for coronary vasospasm. |
2011 |
Circ. J. |
pmid:21378446
|
Du H et al. |
Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ. |
2011 |
Br. J. Pharmacol. |
pmid:21501147
|
Varma D et al. |
Comparison of UHPLC and HPLC methods for the assay of prostanoids: "are the methods equivalent in terms of accuracy and precision?". |
2011 |
Bioanalysis |
pmid:21510759
|
Kamauchi S and Urade Y |
[Hematopoietic prostaglandin D synthase inhibitors for the treatment of duchenne muscular dystrophy]. |
2011 |
Brain Nerve |
pmid:22068479
|
Leamy AW et al. |
Curcumin ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) activates and desensitizes the nociceptor ion channel TRPA1. |
2011 |
Neurosci. Lett. |
pmid:21855605
|
Zheng S et al. |
Novel biphasic role of LipoxinA(4) on expression of cyclooxygenase-2 in lipopolysaccharide-stimulated lung fibroblasts. |
2011 |
Mediators Inflamm. |
pmid:21765620
|
Hernandez JM and Janssen LJ |
Thromboxane prostanoid receptor activation amplifies airway stretch-activated contractions assessed in perfused intact bovine bronchial segments. |
2011 |
J. Pharmacol. Exp. Ther. |
pmid:21768224
|
He P et al. |
Oxidative stress suppresses cysteinyl leukotriene generation by mouse bone marrow-derived mast cells. |
2011 |
J. Biol. Chem. |
pmid:21233206
|
Kitz K et al. |
15-Deoxy-Δ12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species. |
2011 |
Free Radic. Biol. Med. |
pmid:21236332
|
Hossain MS et al. |
Development of enzyme-linked immunosorbent assay for Δ12-prostaglandin J2 and its application to the measurement of the endogenous product generated by cultured adipocytes during the maturation phase. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21237281
|
Aung G et al. |
Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines. |
2011 |
Immunology |
pmid:21214543
|
Chowdhury AA et al. |
Sustained expression of lipocalin-type prostaglandin D synthase in the antisense direction positively regulates adipogenesis in cloned cultured preadipocytes. |
2011 |
Biochem. Biophys. Res. Commun. |
pmid:21726533
|
Hovsepian E et al. |
Modulation of inflammatory response and parasitism by 15-Deoxy-Δ(12,14) prostaglandin J(2) in Trypanosoma cruzi-infected cardiomyocytes. |
2011 |
Int. J. Parasitol. |
pmid:21215746
|
Song NY et al. |
Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells. |
2011 |
Chem. Res. Toxicol. |
pmid:21728338
|
Lotz C et al. |
Activation of peroxisome-proliferator-activated receptors α and γ mediates remote ischemic preconditioning against myocardial infarction in vivo. |
2011 |
Exp. Biol. Med. (Maywood) |
pmid:21163821
|
Charles RL et al. |
Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation. |
2011 |
Circ. Res. |
pmid:21164107
|
Eguchi M et al. |
Lipopolysaccharide induces proinflammatory cytokines and chemokines in experimental otitis media through the prostaglandin D2 receptor (DP)-dependent pathway. |
2011 |
Clin. Exp. Immunol. |
pmid:21166666
|
Oh YC et al. |
Anti-allergic effects of sinomenine by inhibition of prostaglandin Dâ‚‚ and leukotriene Câ‚„ in mouse bone marrow-derived mast cells. |
2011 |
Immunopharmacol Immunotoxicol |
pmid:21080779
|
Cichocka-Jarosz E et al. |
Serum tryptase level is a better predictor of systemic side effects than prostaglandin D2 metabolites during venom immunotherapy in children. |
2011 |
J Investig Allergol Clin Immunol |
pmid:21721371
|
Nabe T et al. |
Inhibition of hematopoietic prostaglandin D synthase improves allergic nasal blockage in guinea pigs. |
2011 |
Prostaglandins Other Lipid Mediat. |
pmid:21601002
|
Joos H et al. |
Single impact trauma in human early-stage osteoarthritic cartilage: implication of prostaglandin D2 but no additive effect of IL-1β on cell survival. |
2011 |
Int. J. Mol. Med. |
pmid:21567074
|
Shao Z et al. |
Choroidal involution is a key component of oxygen-induced retinopathy. |
2011 |
Invest. Ophthalmol. Vis. Sci. |
pmid:21546530
|
Ji Y et al. |
Nutrient-induced inflammation in the intestine. |
2011 |
Curr Opin Clin Nutr Metab Care |
pmid:21587069
|
Jakob S and Lovell-Badge R |
Sex determination and the control of Sox9 expression in mammals. |
2011 |
FEBS J. |
pmid:21281448
|
Wang JJ and Mak OT |
Induction of apoptosis in non-small cell lung carcinoma A549 cells by PGDâ‚‚ metabolite, 15d-PGJâ‚‚. |
2011 |
Cell Biol. Int. |
pmid:21999315
|
Seno T et al. |
15-Deoxy-Δ¹²,¹ⴠprostaglandin J₂ reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice. |
2011 |
PLoS ONE |
pmid:22003398
|
Birbian N et al. |
No association of PTGDR -441C/T polymorphism with asthma in a North Indian population. |
2011 |
Dis. Markers |
pmid:22182808
|