PGD2
Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.
Cross Reference
Introduction
To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PGD2?
PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PGD2
PubChem Associated disorders and diseases
What pathways are associated with PGD2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PGD2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with PGD2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PGD2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with PGD2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PGD2?
Knock-out
Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).
Rodent Model
Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with PGD2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mutalithas K et al. | CRTH2 expression on T cells in asthma. | 2010 | Clin. Exp. Immunol. | pmid:20491797 |
| Koharudin LM et al. | Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20231490 |
| Norman P | DP(2) receptor antagonists in development. | 2010 | Expert Opin Investig Drugs | pmid:20615077 |
| Pedersen PJ et al. | Prostaglandin phospholipid conjugates with unusual biophysical and cytotoxic properties. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20591667 |
| Bai YJ et al. | A LC-MS-based method for quantification of biomarkers from serum of allergic rats. | 2010 | Molecules | pmid:20657485 |
| Vong L et al. | A pro-resolution mediator, prostaglandin D(2), is specifically up-regulated in individuals in long-term remission from ulcerative colitis. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20547854 |
| Lehmann GM et al. | Novel anti-adipogenic activity produced by human fibroblasts. | 2010 | Am. J. Physiol., Cell Physiol. | pmid:20554910 |
| Schuligoi R et al. | CRTH2 and D-type prostanoid receptor antagonists as novel therapeutic agents for inflammatory diseases. | 2010 | Pharmacology | pmid:20559016 |
| Kaur S et al. | Induction of prostaglandin D2 through the p38 MAPK pathway is responsible for the antipruritic activity of sertaconazole nitrate. | 2010 | J. Invest. Dermatol. | pmid:20505747 |
| Rodrigues WF et al. | 15d-PGJ(2) modulates acute immune responses to Trypanosoma cruzi infection. | 2010 | Mem. Inst. Oswaldo Cruz | pmid:20428671 |
| Blancou P and Anegon I | Editorial: Heme oxygenase-1 and dendritic cells: what else? | 2010 | J. Leukoc. Biol. | pmid:20123679 |
| Nørregaard R et al. | Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20147610 |
| Dionne S et al. | PPARgamma ligand 15-deoxy-delta 12,14-prostaglandin J2 sensitizes human colon carcinoma cells to TWEAK-induced apoptosis. | 2010 | Anticancer Res. | pmid:20150631 |
| Zhu F et al. | Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases. | 2010 | Cell Death Differ. | pmid:20150912 |
| Orlichenko LS et al. | Transcriptional regulation of CXC-ELR chemokines KC and MIP-2 in mouse pancreatic acini. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20671197 |
| Fujitani Y et al. | Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo. | 2010 | FEBS J. | pmid:20136655 |
| Syed MA et al. | Expression of TREM-1 is inhibited by PGD2 and PGJ2 in macrophages. | 2010 | Exp. Cell Res. | pmid:20797396 |
| Lou HQ et al. | [CRTH2 antagonist ameliorates airway inflammation in rats with asthma]. | 2010 | Zhejiang Da Xue Xue Bao Yi Xue Ban | pmid:20175238 |
| He R et al. | The prostaglandin Dâ‚‚ receptor CRTH2 is important for allergic skin inflammation after epicutaneous antigen challenge. | 2010 | J. Allergy Clin. Immunol. | pmid:20713302 |
| Schell C et al. | 15-Deoxy-delta 12-14-prostaglandin-J2 induces hypertrophy and loss of contractility in human testicular peritubular cells: implications for human male fertility. | 2010 | Endocrinology | pmid:20133451 |
| Poncin S et al. | Oxidative stress: a required condition for thyroid cell proliferation. | 2010 | Am. J. Pathol. | pmid:20093493 |
| Wang Y et al. | Role of cyclooxygenase-2 signaling pathway dysfunction in unexplained recurrent spontaneous abortion. | 2010 | Chin. Med. J. | pmid:20819509 |
| Xiao Y et al. | 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-gamma-dependent and mediated by the caspase-3-dependent apoptotic pathway. | 2010 | FEBS J. | pmid:20050918 |
| van den Brule S et al. | The D prostanoid receptor agonist BW245C [(4S)-(3-[(3R,S)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxo)-4-imidazolidineheptanoic acid] inhibits fibroblast proliferation and bleomycin-induced lung fibrosis in mice. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20719937 |
| Watanabe K et al. | 15-deoxy-delta 12,14-prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis. | 2010 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:20056897 |
| Kar R et al. | Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20678484 |
| Satoh T et al. | Indomethacin-induced reduction in CRTH2 in eosinophilic pustular folliculitis (Ofuji's disease): a proposed mechanism of action. | 2010 | Acta Derm. Venereol. | pmid:20107720 |
| Akin C et al. | Mast cell activation syndrome: Proposed diagnostic criteria. | 2010 | J. Allergy Clin. Immunol. | pmid:21035176 |
| Veliça P et al. | Prostaglandin D2 inhibits C2C12 myogenesis. | 2010 | Mol. Cell. Endocrinol. | pmid:20109525 |
| Gallant MA et al. | Increased concentrations of prostaglandin D2 during post-fracture bone remodeling. | 2010 | J. Rheumatol. | pmid:20080921 |
| Zhang HX et al. | Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2). | 2010 | Exp. Neurol. | pmid:20083106 |
| Katura T et al. | 15-Deoxy-delta 12,14-prostaglandin J2 biphasically regulates the proliferation of mouse hippocampal neural progenitor cells by modulating the redox state. | 2010 | Mol. Pharmacol. | pmid:20086036 |
| Buga GM et al. | L-4F alters hyperlipidemic (but not healthy) mouse plasma to reduce platelet aggregation. | 2010 | Arterioscler. Thromb. Vasc. Biol. | pmid:19965777 |
| Roy SJ et al. | Characterization of C-terminal tail determinants involved in CRTH2 receptor trafficking: identification of a recycling motif. | 2010 | Eur. J. Pharmacol. | pmid:20035740 |
| Lin TY and London CA | Characterization and modulation of canine mast cell derived eicosanoids. | 2010 | Vet. Immunol. Immunopathol. | pmid:20036014 |
| Byrns MC et al. | Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer. | 2010 | J. Steroid Biochem. Mol. Biol. | pmid:20036328 |
| Moraes LA et al. | Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation. | 2010 | J. Thromb. Haemost. | pmid:20040043 |
| Subra C et al. | Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. | 2010 | J. Lipid Res. | pmid:20424270 |
| Zhang F et al. | Peroxisome proliferator-activated receptor-gamma agonists suppress iNOS expression induced by LPS in rat primary Schwann cells. | 2010 | J. Neuroimmunol. | pmid:19942298 |
| Zorrilla S et al. | Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization. | 2010 | Anal. Biochem. | pmid:20025845 |
| Kim NJ et al. | Concise and enantioselective total synthesis of 15-deoxy-Δ-(12,14)-prostaglandin J(2). | 2010 | J. Org. Chem. | pmid:20929274 |
| Pérez-Nievas BG et al. | Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated. | 2010 | J Neuroinflammation | pmid:20929574 |
| Li H et al. | Serum amyloid A activates peroxisome proliferator-activated receptor γ through extracellularly regulated kinase 1/2 and COX-2 expression in hepatocytes. | 2010 | Biochemistry | pmid:20853849 |
| Bancos S et al. | Induction of heme oxygenase-1 in normal and malignant B lymphocytes by 15-deoxy-Delta(12,14)-prostaglandin J(2) requires Nrf2. | 2010 | Cell. Immunol. | pmid:20064636 |
| Pacienza N et al. | 15-deoxy-Delta(12,14)-PGJ(2) induces cell cycle arrest and apoptosis of haematopoietic progenitors. | 2010 | Br. J. Haematol. | pmid:19764987 |
| Oh YC et al. | Anti-allergic activity of a platycodon root ethanol extract. | 2010 | Int J Mol Sci | pmid:20717534 |
| Lee CM et al. | Prostaglandin expression profile in hypoxic osteoblastic cells. | 2010 | J. Bone Miner. Metab. | pmid:19471853 |
| Cerrato S et al. | Effects of palmitoylethanolamide on immunologically induced histamine, PGD2 and TNFalpha release from canine skin mast cells. | 2010 | Vet. Immunol. Immunopathol. | pmid:19625089 |
| Kim SH et al. | Toluene diisocyanate (TDI) regulates haem oxygenase-1/ferritin expression: implications for toluene diisocyanate-induced asthma. | 2010 | Clin. Exp. Immunol. | pmid:20345975 |
| Zimmer M et al. | The connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin J2. | 2010 | Cancer Res. | pmid:20354189 |
| Koyama M et al. | Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis. | 2010 | Clin. Cancer Res. | pmid:20371690 |
| Kim DH et al. | 15-Deoxy-Delta(12,14)-prostaglandin J(2) stabilizes, but functionally inactivates p53 by binding to the cysteine 277 residue. | 2010 | Oncogene | pmid:20208557 |
| Cho HY et al. | Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice. | 2010 | Am. J. Respir. Crit. Care Med. | pmid:20224069 |
| Krall CM et al. | Food deprivation alters thermoregulatory responses to lipopolysaccharide by enhancing cryogenic inflammatory signaling via prostaglandin D2. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20393159 |
| Lee JJ et al. | The protective effects of paclitaxel on platelet aggregation through the inhibition of thromboxane A2 synthase. | 2010 | Arch. Pharm. Res. | pmid:20361303 |
| Pérez-Novo CA et al. | CRTH2 mediates the activation of human Th2 cells in response to PGD(2) released from IgE/anti-IgE treated nasal polyp tissue. | 2010 | Allergy | pmid:19839971 |
| Mo C et al. | PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway. | 2010 | Cell. Signal. | pmid:19922793 |
| Kanda N et al. | Prostaglandin D2 induces the production of human beta-defensin-3 in human keratinocytes. | 2010 | Biochem. Pharmacol. | pmid:19925780 |
| Diers AR et al. | Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. | 2010 | Biochem. J. | pmid:19916962 |
| Morgenweck J et al. | Activation of peroxisome proliferator-activated receptor gamma in brain inhibits inflammatory pain, dorsal horn expression of Fos, and local edema. | 2010 | Neuropharmacology | pmid:19891980 |
| Liu JY et al. | Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model. | 2010 | Biochem. Pharmacol. | pmid:19896470 |
| Shimura C et al. | Dendritic cells express hematopoietic prostaglandin D synthase and function as a source of prostaglandin D2 in the skin. | 2010 | Am. J. Pathol. | pmid:20008150 |
| Yamaguchi S et al. | Delta12-prostaglandin J2 as a product and ligand of human serum albumin: formation of an unusual covalent adduct at His146. | 2010 | J. Am. Chem. Soc. | pmid:20014793 |
| Lin TH et al. | Upregulation of heme oxygenase-1 inhibits the maturation and mineralization of osteoblasts. | 2010 | J. Cell. Physiol. | pmid:20020468 |
| Hovsepian E et al. | 15-deoxy-Delta12,14 prostaglandin GJ2 but not rosiglitazone regulates metalloproteinase 9, NOS-2, and cyclooxygenase 2 expression and functions by peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms in cardiac cells. | 2010 | Shock | pmid:19997048 |
| Théoleyre S et al. | HtrA3 is regulated by 15-deoxy-Delta12,14-prostaglandin J2 independently of PPARgamma in clear cell renal cell carcinomas. | 2010 | Biochem. Biophys. Res. Commun. | pmid:19951697 |
| Shim J et al. | The peroxisome proliferator-activated receptor gamma ligands, pioglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2), have antineoplastic effects against hepatitis B virus-associated hepatocellular carcinoma cells. | 2010 | Int. J. Oncol. | pmid:19956851 |
| Bach-Ngohou K et al. | Enteric glia modulate epithelial cell proliferation and differentiation through 15-deoxy-12,14-prostaglandin J2. | 2010 | J. Physiol. (Lond.) | pmid:20478974 |
| Masoodi M et al. | Prostaglandin D production in FM55 melanoma cells is regulated by alpha-melanocyte-stimulating hormone and is not related to melanin production. | 2010 | Exp. Dermatol. | pmid:20482620 |
| Hilliard M et al. | The anti-inflammatory prostaglandin 15-deoxy-delta(12,14)-PGJ2 inhibits CRM1-dependent nuclear protein export. | 2010 | J. Biol. Chem. | pmid:20457605 |
| Yokoyama Y et al. | 15-Deoxy-Delta12,14-prostaglandin J2 inhibits angiotensin II-induced fibronectin expression via hepatocyte growth factor induction in human peritoneal mesothelial cells. | 2010 | Ther Apher Dial | pmid:20438519 |
| Romanovsky AA and Garami A | Prostaglandin riddles in energy metabolism: E is for excess, D is for depletion. Focus on "Food deprivation alters thermoregulatory responses to lipopolysaccharide by enhancing cryogenic inflammatory signaling via prostaglandin D2". | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20410482 |
| Shiraya K et al. | A novel transporter of SLC22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules. | 2010 | J. Biol. Chem. | pmid:20448048 |
| Mishra N et al. | Inhibition of mitochondrial division through covalent modification of Drp1 protein by 15 deoxy-Delta(12,14)-prostaglandin J2. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20307494 |
| Guo N et al. | Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease. | 2010 | J. Biol. Chem. | pmid:20308056 |
| Poncin S et al. | N-acetylcysteine and 15 deoxy-{delta}12,14-prostaglandin J2 exert a protective effect against autoimmune thyroid destruction in vivo but not against interleukin-1{alpha}/interferon {gamma}-induced inhibitory effects in thyrocytes in vitro. | 2010 | Am. J. Pathol. | pmid:20489149 |
| Galvão Nascimento N et al. | Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators involved. | 2010 Feb-Mar | Toxicon | pmid:19703484 |
| Higuchi S et al. | IL-4 mediates dicloxacillin-induced liver injury in mice. | 2011 | Toxicol. Lett. | pmid:21094227 |
| Afrin LB | Polycythemia from mast cell activation syndrome: lessons learned. | 2011 | Am. J. Med. Sci. | pmid:21642812 |
| Kajiwara D et al. | Role of hematopoietic prostaglandin D synthase in biphasic nasal obstruction in guinea pig model of experimental allergic rhinitis. | 2011 | Eur. J. Pharmacol. | pmid:21645503 |
| Erttmann SF et al. | PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2. | 2011 | Free Radic. Biol. Med. | pmid:21651978 |
| Chiba T et al. | The opposing role of two prostaglandin D2 receptors, DP and CRTH2, in human eosinophil migration. | 2011 | Ann. Allergy Asthma Immunol. | pmid:21624751 |
| Liu TY et al. | [Advances in the study of histaminergic systems and sleep-wake regulation]. | 2011 | Yao Xue Xue Bao | pmid:21626776 |
| Zhang Y et al. | Simultaneous and high-throughput quantitation of urinary tetranor PGDM and tetranor PGEM by online SPE-LC-MS/MS as inflammatory biomarkers. | 2011 | J Mass Spectrom | pmid:21706677 |
| Ugajin T et al. | FcεRI, but not FcγR, signals induce prostaglandin D2 and E2 production from basophils. | 2011 | Am. J. Pathol. | pmid:21712025 |
| Tobiasova Z et al. | Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. | 2011 | Circulation | pmid:21690493 |
| Menon R et al. | Amniotic fluid eicosanoids in preterm and term births: effects of risk factors for spontaneous preterm labor. | 2011 | Obstet Gynecol | pmid:21691170 |
| Ebersberger A et al. | Effects of prostaglandin D2 on tetrodotoxin-resistant Na+ currents in DRG neurons of adult rat. | 2011 | Pain | pmid:21345590 |
| Lalier L et al. | Prostaglandins antagonistically control Bax activation during apoptosis. | 2011 | Cell Death Differ. | pmid:20966963 |
| Sharma I et al. | In vitro effects of peroxisome proliferator-activated receptor-γ ligands on gene expression in lipopolysaccharide-induced endometrial and endometriotic stromal cells. | 2011 | Fertil. Steril. | pmid:20970133 |
| Larsson AK et al. | Prostaglandin Dâ‚‚ induces contractions through activation of TP receptors in peripheral lung tissue from the guinea pig. | 2011 | Eur. J. Pharmacol. | pmid:21872585 |
| Degousee N et al. | Group V phospholipase A2 in bone marrow-derived myeloid cells and bronchial epithelial cells promotes bacterial clearance after Escherichia coli pneumonia. | 2011 | J. Biol. Chem. | pmid:21849511 |
| Mesquita-Santos FP et al. | Co-operative signalling through DP(1) and DP(2) prostanoid receptors is required to enhance leukotriene C(4) synthesis induced by prostaglandin D(2) in eosinophils. | 2011 | Br. J. Pharmacol. | pmid:20973774 |
| Wienecke T et al. | Discrepancy between strong cephalic arterial dilatation and mild headache caused by prostaglandin Dâ‚‚ (PGDâ‚‚). | 2011 | Cephalalgia | pmid:20974593 |
| El-Shazly AE et al. | IFN-γ and TNF-α potentiate prostaglandin D2-induced human eosinophil chemotaxis through up-regulation of CRTH2 surface receptor. | 2011 | Int. Immunopharmacol. | pmid:21835268 |
| Kuehn HS et al. | Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release. | 2011 | J. Biol. Chem. | pmid:20980255 |
| Surh YJ et al. | 15-Deoxy-Δ¹²,¹â´-prostaglandin Jâ‚‚, an electrophilic lipid mediator of anti-inflammatory and pro-resolving signaling. | 2011 | Biochem. Pharmacol. | pmid:21843512 |
| Lu Y et al. | Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation. | 2011 | Biochem. Pharmacol. | pmid:21907188 |
| Burke SJ and Collier JJ | The gene encoding cyclooxygenase-2 is regulated by IL-1β and prostaglandins in 832/13 rat insulinoma cells. | 2011 | Cell. Immunol. | pmid:21885043 |
| Crosignani S et al. | Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases. | 2011 | J. Med. Chem. | pmid:21916510 |