| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ureteral Obstruction | D014517 | 10 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Liver Cirrhosis, Experimental | D008106 | 36 associated lipids |
| Hypersensitivity | D006967 | 22 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Rhinitis | D012220 | 10 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
PGD2
Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.
Cross Reference
Introduction
To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PGD2?
PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PGD2
PubChem Associated disorders and diseases
What pathways are associated with PGD2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PGD2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with PGD2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PGD2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with PGD2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PGD2?
Knock-out
Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).
Rodent Model
Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with PGD2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wise H | Characterization of chimeric prostacyclin/prostaglandin D(2) receptors. | 1999 | Eur. J. Pharmacol. | pmid:10611468 |
| Galli A et al. | Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells. | 2000 | Hepatology | pmid:10613734 |
| Uehara Y | [Prostaglandin D2]. | 1999 | Nippon Rinsho | pmid:10635955 |
| Rossi A et al. | Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. | 2000 | Nature | pmid:10638762 |
| Clark RB et al. | The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. | 2000 | J. Immunol. | pmid:10640751 |
| Reilly CM et al. | Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists. | 2000 | J. Immunol. | pmid:10640767 |
| Dumont I et al. | Regulation of endothelial nitric oxide synthase by PGD(2) in the developing choroid. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10644584 |
| Kuwamoto K et al. | Possible involvement of enhanced prostaglandin E2 production in the photosensitivity in xeroderma pigmentosum group A model mice. | 2000 | J. Invest. Dermatol. | pmid:10651981 |
| Nojima H et al. | Arachidonic acid and prostaglandin D2 cooperatively accelerate desensitization of nicotinic acetylcholine receptor channel in mouse skeletal muscles. | 2000 | Brain Res. | pmid:10661520 |
| Herschman HR | Function and regulation of prostaglandin synthase 2. | 1999 | Adv. Exp. Med. Biol. | pmid:10667302 |
| Murakami M et al. | Regulation of prostaglandin, leukotriene, and platelet-activating factor metabolism in mast cells. | 1999 | Adv. Exp. Med. Biol. | pmid:10667307 |
| Urade Y and Hayaishi O | Prostaglandin D synthase: structure and function. | 2000 | Vitam. Horm. | pmid:10668396 |
| Castrillo A et al. | Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-Delta(12,14)-prostaglandin J(2) in activated murine macrophages. | 2000 | Mol. Cell. Biol. | pmid:10669746 |
| Butler R et al. | Nonapoptotic cell death associated with S-phase arrest of prostate cancer cells via the peroxisome proliferator-activated receptor gamma ligand, 15-deoxy-delta12,14-prostaglandin J2. | 2000 | Cell Growth Differ. | pmid:10672903 |
| Liu JH | Circadian variations of prostaglandins in the rabbit aqueous humor. | 2000 | J Ocul Pharmacol Ther | pmid:10673131 |
| Kowalski ML et al. | Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:10673176 |
| Sugiyama H et al. | Peroxisome proliferator-activated receptors are expressed in mouse bone marrow-derived mast cells. | 2000 | FEBS Lett. | pmid:10675550 |
| Tanaka K et al. | Cutting edge: differential production of prostaglandin D2 by human helper T cell subsets. | 2000 | J. Immunol. | pmid:10679060 |
| Charpigny G et al. | Correlation of increased concentration of ovine endometrial cyclooxygenase 2 with the increase in PGE2 and PGD2 in the late luteal phase. | 1999 | J. Reprod. Fertil. | pmid:10690199 |
| Yamashita M et al. | Inhibition by troglitazone of the antigen-induced production of leukotrienes in immunoglobulin E-sensitized RBL-2H3 cells. | 2000 | Br. J. Pharmacol. | pmid:10694244 |