| MeSH term | MeSH ID | Detail |
|---|---|---|
| Brain Damage, Chronic | D001925 | 6 associated lipids |
| Leukodystrophy, Globoid Cell | D007965 | 6 associated lipids |
| Fetal Alcohol Spectrum Disorders | D063647 | 6 associated lipids |
| Sneezing | D012912 | 6 associated lipids |
| Xeroderma Pigmentosum | D014983 | 6 associated lipids |
| Hyperlipoproteinemia Type IV | D006953 | 6 associated lipids |
| Leukemia, Megakaryoblastic, Acute | D007947 | 7 associated lipids |
| Folliculitis | D005499 | 7 associated lipids |
| Multiple Sclerosis, Relapsing-Remitting | D020529 | 7 associated lipids |
| Carotid Artery Thrombosis | D002341 | 7 associated lipids |
PGD2
Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.
Cross Reference
Introduction
To understand associated biological information of PGD2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PGD2?
PGD2 is suspected in Asthma, Dehydration, Allergic rhinitis NOS, Rhinitis, Infertility, Pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PGD2
PubChem Associated disorders and diseases
What pathways are associated with PGD2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PGD2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PGD2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PGD2?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PGD2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PGD2?
Knock-out
Knock-out are used in the study 'Multiple roles of the prostaglandin D2 signaling pathway in reproduction.' (Rossitto M et al., 2015).
Rodent Model
Rodent Model are used in the study 'PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation.' (Kong D et al., 2016).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PGD2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hayaishi O | [The brain and prostaglandins]. | 1983 | Rinsho Shinkeigaku | pmid:6587956 |
| Ji JD et al. | Inhibition of IL-10-induced STAT3 activation by 15-deoxy-Delta12,14-prostaglandin J2. | 2005 | Rheumatology (Oxford) | pmid:15840591 |
| Jakob M et al. | Chondrogenesis of expanded adult human articular chondrocytes is enhanced by specific prostaglandins. | 2004 | Rheumatology (Oxford) | pmid:15113997 |
| Nicolaidis S et al. | [Variations of hypothalamic and cortical prostaglandins and monoamines reveal transitions in arousal states: microdialysis study in the rat]. | 2001 | Rev. Neurol. (Paris) | pmid:11924034 |
| Dorta-Contreras AJ et al. | [Beta trace protein in the cerebrospinal fluid and serum in meningoencephalitis]. | 1998 | Rev Neurol | pmid:9585948 |
| Carsin A et al. | [Physiopathology of aspirin intolerant asthma]. | 2012 | Rev Mal Respir | pmid:22405107 |
| Mendoza Magaña MJ et al. | [Anaphylaxis and anaphylactic shock]. | 2007 Mar-Apr | Rev Alerg Mex | pmid:17542244 |
| Qiu Z et al. | Cough reflex sensitivity and airway inflammation in patients with chronic cough due to non-acid gastro-oesophageal reflux. | 2011 | Respirology | pmid:21342332 |
| Miadonna A et al. | Mediators and allergic inflammation of human airways. | 1988 | Respiration | pmid:2466314 |
| Peters SP et al. | The pharmacologic control of mediator release from human basophils and mast cells. | 1986 | Respiration | pmid:3494282 |
| Honma S et al. | Effects of naturally-occurring acid fog on inflammatory mediators in airway and pulmonary functions in asthmatic patients. | 2000 | Respir Med | pmid:11059945 |
| Rossitto M et al. | Multiple roles of the prostaglandin D2 signaling pathway in reproduction. | 2015 | Reproduction | pmid:25269616 |
| Jawerbaum A et al. | Peroxynitrites and impaired modulation of nitric oxide concentrations in embryos from diabetic rats during early organogenesis. | 2005 | Reproduction | pmid:16264098 |
| Tinfo N and Komar C | Potential role for peroxisome proliferator-activated receptor gamma in regulating luteal lifespan in the rat. | 2007 | Reproduction | pmid:17244745 |
| Jawerbaum A et al. | Modulation of nitric oxide concentration and lipid metabolism by 15-deoxy Delta12,14prostaglandin J2 in embryos from control and diabetic rats during early organogenesis. | 2002 | Reproduction | pmid:12417000 |
| Ulbrich SE et al. | Quantitative characterization of prostaglandins in the uterus of early pregnant cattle. | 2009 | Reproduction | pmid:19470711 |
| Capobianco E et al. | 15-Deoxy-Delta12,14-prostaglandin J2 and peroxisome proliferator-activated receptor gamma (PPARgamma) levels in term placental tissues from control and diabetic rats: modulatory effects of a PPARgamma agonist on nitridergic and lipid placental metabolism. | 2005 | Reprod. Fertil. Dev. | pmid:15899154 |
| Bogacka I et al. | The involvement of peroxisome proliferator activated receptors (PPARs) in prostaglandin F2α production by porcine endometrium. | 2013 | Reprod Biol | pmid:24287039 |
| Higashihara H et al. | Hypoxia-reoxygenation enhances interleukin-8 production from U937 human monocytic cells. | 2004 | Redox Rep. | pmid:15720834 |
| Takagi T et al. | A PPAR-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J(2), inhibited gastric mucosal injury induced by ischemia-reperfusion in rats. | 2004 | Redox Rep. | pmid:15720836 |