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Resident peritoneal macrophages and mast cells are important cellular sites of COX-1 and COX-2 activity during acute peritoneal inflammation. |
2009 Nov-Dec |
Arch. Immunol. Ther. Exp. (Warsz.) |
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Effects of Bothrops asper snake venom on the expression of cyclooxygenases and production of prostaglandins by peritoneal leukocytes in vivo, and by isolated neutrophils and macrophages in vitro. |
2009 Feb-Mar |
Prostaglandins Leukot. Essent. Fatty Acids |
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Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2. |
2009 |
Leukemia |
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Lipid metabolite levels of prostaglandin D2 and eicosapentaenoic acid recovered from bronchoalveolar lavage fluid correlate with lung function of chronic obstructive pulmonary disease patients and controls. |
2009 |
Electrophoresis |
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Lipopolysaccharide-dependent interaction between PU.1 and c-Jun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages. |
2009 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
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Prostaglandin D(2) sustains the pyrogenic effect of prostaglandin E(2). |
2009 |
Eur. J. Pharmacol. |
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Peroxisome proliferator-activated receptor gamma agonists enhance lung maturation in a neonatal rat model. |
2009 |
Pediatr. Res. |
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Expression and characterization of PGD2 receptors in chronic rhinosinusitis: modulation of DP and CRTH2 by PGD2. |
2009 |
Int. Arch. Allergy Immunol. |
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The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J(2) delays lipopolysaccharide-induced preterm delivery and reduces mortality in the newborn mouse. |
2009 |
Endocrinology |
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Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen. |
2009 |
Neurochem. Res. |
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Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor. |
2009 |
Dig. Dis. Sci. |
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15-Deoxy-delta 12, 14-prostaglandin J2 induces upregulation of multidrug resistance-associated protein 1 via Nrf2 activation in human breast cancer cells. |
2009 |
Ann. N. Y. Acad. Sci. |
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15-Deoxy-delta 12, 14,-prostaglandin J2 suppresses nuclear factor-kappaB-mediated apoptosis of Helicobacter pylori-infected gastric epithelial cells. |
2009 |
Ann. N. Y. Acad. Sci. |
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Increased expression and cellular localization of lipocalin-type prostaglandin D synthase in Helicobacter pylori-induced gastritis. |
2009 |
J. Pathol. |
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2009 |
Nippon Rinsho |
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Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma. |
2009 |
World J. Gastroenterol. |
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Biomarkers in the diagnosis of anaphylaxis: making nature disclose her mysteries. |
2009 |
Clin. Exp. Allergy |
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A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation. |
2009 |
Int. Immunol. |
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Antagonism of CRTH2 ameliorates chronic epicutaneous sensitization-induced inflammation by multiple mechanisms. |
2009 |
Int. Immunol. |
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Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. |
2009 |
Endocrinology |
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The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation. |
2009 |
J. Biol. Chem. |
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R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. |
2009 |
Pharm. Res. |
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Byrns MC and Penning TM |
Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs. |
2009 |
Chem. Biol. Interact. |
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Methods for imaging and detecting modification of proteins by reactive lipid species. |
2009 |
Free Radic. Biol. Med. |
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A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells. |
2009 |
Oncogene |
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Activation of peroxisome proliferator-activated receptor-gamma inhibits transforming growth factor-beta1 induction of connective tissue growth factor and extracellular matrix in hypertrophic scar fibroblasts in vitro. |
2009 |
Arch. Dermatol. Res. |
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Quantitative characterization of prostaglandins in the uterus of early pregnant cattle. |
2009 |
Reproduction |
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A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep. |
2009 |
Clin. Exp. Allergy |
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Potential effects of peroxisome proliferator-activated receptor activator on LPS-induced lung injury in rats. |
2009 |
Pulm Pharmacol Ther |
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Glucocorticoid protects rodent hearts from ischemia/reperfusion injury by activating lipocalin-type prostaglandin D synthase-derived PGD2 biosynthesis. |
2009 |
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Eicosapentaenoic acid is more effective than docosahexaenoic acid in inhibiting proinflammatory mediator production and transcription from LPS-induced human asthmatic alveolar macrophage cells. |
2009 |
Clin Nutr |
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2009 |
J. Neurochem. |
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15-Deoxy-Delta(12,14)-prostaglandin-J(2) reveals a new pVHL-independent, lysosomal-dependent mechanism of HIF-1alpha degradation. |
2009 |
Cell. Mol. Life Sci. |
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Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport. |
2009 |
Free Radic. Biol. Med. |
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2009 |
Cardiovasc. Res. |
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Novel function of CRTH2 in preventing apoptosis of human Th2 cells through activation of the phosphatidylinositol 3-kinase pathway. |
2009 |
J. Immunol. |
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2009 |
Int. Arch. Allergy Immunol. |
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15-Deoxy-Delta(12,14)-prostaglandin J2 induces IL-8 and GM-CSF in a human airway epithelial cell line (NCI-H292). |
2009 |
Int. Arch. Allergy Immunol. |
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Prostaglandin D2 produced by hematopoietic prostaglandin D synthase contributes to LPS-induced fever. |
2009 |
J. Physiol. Pharmacol. |
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Butterfield JH |
Survey of aspirin administration in systemic mastocytosis. |
2009 |
Prostaglandins Other Lipid Mediat. |
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The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation. |
2009 |
Development |
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Genistein induces adipogenesis but inhibits leptin induction in human synovial fibroblasts. |
2009 |
Lab. Invest. |
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The 15-deoxy-Delta12,14-prostaglandin J2 inhibits LPS-stimulated AKT and NF-kappaB activation and suppresses interleukin-6 in osteoblast-like cells MC3T3E-1. |
2009 |
Life Sci. |
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In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties. |
2009 |
Br. J. Pharmacol. |
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CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages. |
2009 |
Cardiovasc. Res. |
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Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands. |
2009 |
Exp. Dermatol. |
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Prakash J et al. |
Albumin-binding and tumor vasculature determine the antitumor effect of 15-deoxy-Delta-(12,14)-prostaglandin-J(2) in vivo. |
2009 |
Neoplasia |
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Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia. |
2009 |
PLoS ONE |
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Pustovrh MC et al. |
MMP/ TIMP balance is modulated in vitro by 15dPGJ(2) in fetuses and placentas from diabetic rats. |
2009 |
Eur. J. Clin. Invest. |
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Genetic mechanisms underlying male sex determination in mammals. |
2009 |
J. Appl. Genet. |
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