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PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes. |
2003 |
Hypertension |
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Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts. |
2003 |
Gastroenterology |
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Structural requirements of cyclopentenone prostaglandins to induce endothelial cell apoptosis. |
2003 |
Biochem. Biophys. Res. Commun. |
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J. Huazhong Univ. Sci. Technol. Med. Sci. |
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Cloning, expression, crystallization, and preliminary X-ray analysis of recombinant mouse lipocalin-type prostaglandin D synthase, a somnogen-producing enzyme. |
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Loss of microglial ramification in microglia-astrocyte cocultures: involvement of adenylate cyclase, calcium, phosphatase, and Gi-protein systems. |
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Glia |
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Peroxisome proliferator-activated receptor gamma activators inhibit MMP-1 production in human synovial fibroblasts likely by reducing the binding of the activator protein 1. |
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Cold temperatures reduce the sensitivity of stored platelets to disaggregating agents. |
2002 |
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PPAR-gamma ligands modulate effects of LPS in stimulated rat synovial fibroblasts. |
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Phospholipase C inhibitors and prostaglandins differentially regulate phosphatidylcholine synthesis in rat renal papilla. Evidence of compartmental regulation of CTP:phosphocholine cytidylyltransferase and CDP-choline:1,2-diacylglycerol cholinephosphotransferase. |
2002 |
Biochim. Biophys. Acta |
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Cytokine |
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PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells. |
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Inhibition of human chondrosarcoma cell growth via apoptosis by peroxisome proliferator-activated receptor-gamma. |
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Br. J. Cancer |
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Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha. |
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Am. J. Physiol. Regul. Integr. Comp. Physiol. |
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Eur. Respir. J. |
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Selective inhibition of cyclooxygenase-2 expression by 15-deoxy-Delta(12,14)(12,14)-prostaglandin J(2) in activated human astrocytes, but not in human brain macrophages. |
2002 |
J. Immunol. |
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Peroxisome-proliferator-activated-receptor gamma (PPARgamma) independent induction of CD36 in THP-1 monocytes by retinoic acid. |
2002 |
Immunology |
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Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase. |
2002 |
Free Radic. Biol. Med. |
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[The roles of the prostanoids played in the body]. |
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Conjugated linoleic acid decreases production of pro-inflammatory products in macrophages: evidence for a PPAR gamma-dependent mechanism. |
2002 |
Biochim. Biophys. Acta |
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In vitro pharmacological characterization of the prostanoid receptor population in the non-pregnant porcine myometrium. |
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Proc. Natl. Acad. Sci. U.S.A. |
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Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism. |
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Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. |
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MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive oxygenated species. |
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Regulation of proinflammatory cytokines in human gestational tissues by peroxisome proliferator-activated receptor-gamma: effect of 15-deoxy-Delta(12,14)-PGJ(2) and troglitazone. |
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Stimulation of peroxisome proliferator-activated receptors alpha and gamma blocks HIV-1 replication and TNFalpha production in acutely infected primary blood cells, chronically infected U1 cells, and alveolar macrophages from HIV-infected subjects. |
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J. Acquir. Immune Defic. Syndr. |
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15-deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial cells: evidence for ERK1/2 signaling pathway blockade. |
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Thromb. Haemost. |
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Biosci. Biotechnol. Biochem. |
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Cultured human intestinal mast cells express functional IL-3 receptors and respond to IL-3 by enhancing growth and IgE receptor-dependent mediator release. |
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Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J(2), to glutathione. |
2002 |
Biochim. Biophys. Acta |
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PPARgamma and vascular inflammation: adding another piece to the puzzle. |
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Circ. Res. |
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Sox-4 is a positive regulator of Hep3B and HepG2 cells' apoptosis induced by prostaglandin (PG)A(2) and delta(12)-PGJ(2). |
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Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation. |
2002 |
Am. J. Physiol., Cell Physiol. |
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Prostaglandin D2 generation by rat peritoneal mast cells stimulated with Datura stramonium agglutinin and its inhibition by haptenic sugar and wheat germ agglutinin. |
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Jpn. J. Pharmacol. |
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Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells. |
2002 |
Int J Gastrointest Cancer |
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The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. |
2002 |
Int J Gastrointest Cancer |
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[Cyclopentenone prostaglandin derivatives as neuroprotective compounds]. |
2002 |
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Decreased antigen-induced eicosanoid release in conjugated linoleic acid-fed guinea pigs. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
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Hypoxic induction of cox-2 regulates proliferation of human pulmonary artery smooth muscle cells. |
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Am. J. Respir. Cell Mol. Biol. |
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15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells. |
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Br. J. Cancer |
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15d-PGJ(2) is acting as a 'dual agent' on the regulation of COX-2 expression in human osteoarthritic chondrocytes. |
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Osteoarthr. Cartil. |
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Gene expression of prostanoid forming enzymes along the rat nephron. |
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A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma. |
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Clin. Exp. Allergy |
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15-Deoxy-prostaglandin J(2) inhibits PDGF-A and -B chain expression in human vascular endothelial cells independent of PPAR gamma. |
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Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion. |
2002 |
Clin. Exp. Metastasis |
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